Master of Science in Nutrition and Integrative Health Tai Sophia Institute NUTR 612: Human Nutrition II: Micronutrients

Fall 2012 3 credits Faculty: Lead Faculty: Bryan Walsh, ND Email: bwalsh@tai.edu or bryanpwalsh@gmail.com Phone: 410.888.9048 x6670 Purpose: This course covers structure, function, and food sources of the micronutrients (vitamins, minerals, trace minerals, and various phytochemicals). The complex function of each nutrient is reviewed, along with interactions, excesses, deficiencies, supplementation, and nutrient synergy. The effects of food processing and agricultural practices on micronutrient density of whole foods will be explored. Students use a variety of methods to compare the micronutrient content of diets. Objectives: To successfully pass this course, the student shall: 1. Recognize the general chemical structure(s)/characteristics of nutritionally significant vitamins and minerals. 2. Describe the functional role(s) performed by specific vitamins and minerals in cellular metabolism/tissue function. 3. Identify factors influencing the physiological requirements for specific vitamins and minerals. 4. Identify the scientific basis for establishing quantitative dietary recommendations for specific vitamins and minerals and appropriate supplementation 5. Identify the metabolic/physiologic/nutritional consequences of a) inadequate amounts of specific vitamins and minerals and b) excessive amounts of specific vitamins and minerals. 6. Identify significant examples of nutrient interactions as illustrated by specific vitamins and minerals. Outcomes: At the end of this course the student will: 1. Have a solid theoretical understanding of the role and relevance of vitamins, minerals, and various trace minerals, accessory nutrients and phytochemicals in human health and disease.

2. Understand the digestion, absorption and metabolism of nutritionally significant vitamins and minerals. 3. Have a broader understanding of the relationship between food intake patterns and micronutrient status in human health. 4. Understand important drug-nutrient interactions and the toxicology of specific nutrients 5. Develop a basic understanding of specific signs and symptoms related to certain nutrient deficiencies Schedule: CLASS SCHEDULE
Date 10/5/12 10/5/12 10/5/12 10/6/12 10/6/12 10/6/12 10/7/12 10/7/12 10/7/12 11/16/12 11/16/12 11/16/12 11/17/12 11/17/12 11/17/12 11/18/12 11/18/12 11/18/12 12/14/12 12/14/12 12/14/12 12/15/12 12/15/12 12/15/12 12/16/12 12/16/12 12/16/12 Time 4:00-5:15pm 5:20-6:35pm 6:45-8:00pm 1:25-2:40pm 2:50-4:05pm 4:15-5:30pm 1:25-2:40pm 2:50-4:05pm 4:15-5:30pm 4:00-5:15pm 5:20-6:35pm 6:45-8:00pm 1:25-2:40pm 2:50-4:05pm 4:15-5:30pm 1:25-2:40pm 2:50-4:05pm 4:15-5:30pm 4:00-5:15pm 5:20-6:35pm 6:45-8:00pm 1:25-2:40pm 2:50-4:05pm 4:15-5:30pm 1:25-2:40pm 2:50-4:05pm 4:15-5:30pm Lecture Course overview and introduction; Review of macronutrient and biochemical principles Review of macronutrient and biochemical principles Overview of micronutrients B1 (Thiamin), B2 (Riboflavin) B3 (Niacin), B5 (Pantothenic Acid) B6 (pyridoxine), B12 (Cobalamin) Folate, choline Biotin, CoQ10, ALA, selective accessory nutrients Vitamin C Review Calcium, Phosphorus, Magnesium Sodium, Potassium, Chloride Zinc, copper, manganese Selenium, Fluoride Iron, Iodine Vitamin A, Vitamin D Vitamin E, Vitamin K Ultratrace Elements, Molybdenum Review Overview of Pharmacology Drug-Nutrient Interactions Drug-Nutrient Interactions Dietary supplement overview claims, regulations, legalities Review Review Final Exam Final Exam Corresponding Reading & Assignments Faculty Walsh Walsh VN: pp 200-208; 265-267 Stipanuk: pp 548-560 Stipanuk: pp 540-547; 620-624 Stipanuk: pp 597-603; 588-596 Stipanuk: pp 565-588 Stipanuk: pp 610-619 Reader Stipanuk: pp 626-648 Stipanuk: pp 721-756 Stipanuk: pp 759-774 Stipanuk: pp 828-845 Stipanuk: pp 867-896 Stipanuk: pp 801-821; 849-864 Stipanuk: pp 683-714 Stipanuk: pp 655-680 Stipanuk: pp 899-909 Reader Reader Reader Reader Walsh Walsh Walsh Walsh Walsh Walsh Walsh Walsh Walsh Walsh TBD TBD Walsh Walsh Walsh Walsh Walsh Walsh Walsh TBD TBD Walsh TBD TBD Walsh

*For all classes, you are encouraged to also read the related information in Visualizing Nutrition.

Prerequisites: None Reading list: Required Reading: 1. Stipanuk, M., Caudill, M. (2012). Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 3rd ed. St Louis: Elsevier Saunders. 2. Grosvenor, M., Smolin, L. (2012). Visualizing Nutrition: Everyday Choices, 2nd ed. Hoboken: Wiley. Reader: TBA Materials: Students should bring textbooks and assigned articles to class for reference. Assignments Students are expected to read all assignments prior to class so they can participate in class discussions. Students are expected to read/work on assignments for a total of 30-60 hours outside of class. These numbers are estimates and will vary based on personal experience and work habits. AT-HOME COURSEWORK - TBA MICRONUTRIENT ANALYSIS PAPER Select a specific system of the body (e.g. cardiovascular, nervous, endocrine, digestive, reproductive, urinary, respiratory, lymphatic, etc.) and write a 5 page paper (minimum) describing all the micronutrients necessary for that system to function optimally. Include specific mechanisms of action of the micronutrients and explain how each mechanism contributes to the proper functioning of the system you choose. Please submit paper electronically to Bryan Walsh, bwalsh@tai.edu by November 18th. *All papers must be submitted with APA referencing style. Evaluation Course Grade: A passing grade is 80 or above. Quizzes (5) Micronutrient Analysis Paper Final Exam 20% 30% 50%

Attendance & Tardiness Policy: Attendance and participation in class are essential for meeting the outcomes and objectives of this course and the program as a whole. Arriving late to class is a disturbance to your classmates and your instructor. It is the students responsibility to stay up-to-date on any missed coursework, regularly checking the course website for updates. If you miss a class, you are encouraged to contact a classmate so they can collect handouts for you. Absences may require that students do extra work to make up for missed material. Plagiarism, Information Literacy & Appropriate Referencing of Sources: Plagiarism: Plagiarism, defined as using the published or unpublished works or ideas of another without properly citing the material used and its source, or presenting another persons work as your own, is an infraction of Tai Sophia Institutes academic honesty policy. Please carefully note all reference sources on your assignments. Information Literacy: Students who are unable to complete homework because of challenges with information literacy skills are asked to seek assistance in the library. The library offers training sessions and support for development of these skills. In some cases, students may be required to complete training sessions in order to pass a course if they demonstrate an inability to meet the demands of the assigned coursework.