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TUBERCULOSIS 2. What are some of the factors which precipitate, predispose, and place Mr.

Dela Cruz at risk into acquiring tuberculosis? Discuss briefly the rationale why these factors lead to the disease.
Predisposing factors for TB infection include the following : - Close contact with large populations of people, i.e., schools, nursing homes, dormitories, prisons, etc. - Poor nutrition - iv drug use - Alcoholism - HIV infection is the #1 predisposing factor for MTB infection. 10 percent of all HIV-positive individuals harbor MTB. This is 400-times the rate associated with the general public Only 3-4% of infected individuals will develop active disease upon initial infection, 5-10% within one year. These percentages are much higher if the individual is HIV+.

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