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\pard\sb0\sl-240{\bkmkstart Pg1}{\bkmkend Pg1}\par\pard\ql \li8139\sb0\sl-184\sl
mult0 \par\pard\ql\li8139\sb0\sl-184\slmult0 \par\pard\ql\li8139\sb0\sl-184\slmu
lt0 \par\pard\ql\li8139\sb115\sl-184\slmult0 \up0 \expndtw-2\charscalex100 \ul0\
nosupersub\cf1\f2\fs16 PESTE PORCINA CLSICA \par\pard\ql \li1701\sb0\sl-276\slmul
t0 \par\pard\ql\li1701\sb64\sl-276\slmult0 \up0 \expndtw0\charscalex108 \ul0\nos
upersub\cf3\f4\fs24 PESTE PORCINA CLSICA \par\pard\qj \li1701\sb0\sl-240\slmult0
\par\pard\qj\li1701\sb0\sl-240\slmult0 \par\pard\qj\li1701\ri1474\sb34\sl-240\sl
mult0 \up0 \expndtw-3\charscalex100 \ul0\nosupersub\cf4\f5\fs20 La peste por
cina clsica es una enfermedad causada por un virus ARN \up0 \ex
pndtw0\charscalex100 perteneciente al gnero Pestivirus de la familia Flavi
viridae, del que existen \up0 \expndtw-3\charscalex100 variantes (cepas) de d
istinta virulencia. \par\pard\qj \li1701\ri1524\sb224\sl-260\slmult0 \up0 \expnd
tw0\charscalex106 Afecta a los cerdos de todas las edades, tanto domsticos como s
alvajes, y se \up0 \expndtw-3\charscalex100 encuentra muy difundida en el mundo.

\par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb15\sl-230\slmult0

\up0 \expndtw-3\charscalex100 Es una enfermedad muy contagiosa y de declaracin o
bligatoria urgente. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\
sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb
60\sl-230\slmult0 \up0 \expndtw0\charscalex110 PATOGENIA \par\pard\qj \li1701\sb
0\sl-240\slmult0 \par\pard\qj\li1701\ri1527\sb2\sl-240\slmult0 \up0 \expndtw0\ch
arscalex100 El nico hospedador natural del virus es el cerdo, tanto domstico como
silvestre, \up0 \expndtw0\charscalex105 aunque el virus es capaz de replicarse e
n otras especies animales. Los jabales \up0 \expndtw-3\charscalex100 pueden actua
r como reservorios. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\
sb19\sl-230\slmult0 \up0 \expndtw-3\charscalex100 Existen diversas vas de infeccin
: \par\pard\ql \li2061\sb0\sl-230\slmult0 \par\pard\ql\li2061\sb40\sl-230\slmult
0 \up0 \expndtw0\charscalex104 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersu
b\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Ingestin. \par\pard\ql \li2061\sb10\
sl-230\slmult0 \up0 \expndtw-2\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?
\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Contacto con la conju
ntiva (mucosas). \par\pard\ql \li2061\sb10\sl-230\slmult0 \up0 \expndtw0\charsca
lex102 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosu
persub\cf4\f5\fs20 Inhalacin. \par\pard\ql \li2061\sb10\sl-230\slmult0 \up0 \ex
pndtw-1\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\
fs20 \ul0\nosupersub\cf4\f5\fs20 Abrasiones de la piel. \par\pard\ql \li2061\
sb10\sl-230\slmult0 \up0 \expndtw-1\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u
8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Inseminacin (seme
n). \par\pard\qj \li1701\sb0\sl-240\slmult0 \par\pard\qj\li1701\ri1532\sb2\sl-24
0\slmult0 \up0 \expndtw-2\charscalex100 Una vez en el animal, el virus se reprod
uce en las amgdalas (infeccin oral o nasal) \line \up0 \expndtw-1\charscalex100 o
en los ganglios linfticos regionales (vaginal, piel). Posteriormente el virus pas
a a \line \up0 \expndtw-2\charscalex100 la sangre. \par\pard\qj \li1701\sb0\sl-2
40\slmult0 \par\pard\qj\li1701\ri1531\sb20\sl-240\slmult0 \up0 \expndtw0\charsca
lex105 Finalmente, se disemina por los rganos diana (bazo, ganglios, rin, pulmn, \up
0 \expndtw0\charscalex100 mdula sea), donde se produce una nueva replicacin viral y
lesiones de carcter \up0 \expndtw-2\charscalex100 hemorrgico. \par\pard\qj \li170
1\ri1516\sb232\sl-250\slmult0 \up0 \expndtw-2\charscalex100 Las principales vas
de eliminacin del virus son las secreciones oronasales y \up0 \expndtw0
\charscalex100 lacrimales, orina y heces. Una vez eliminado el virus, el animal
puede convertirse \up0 \expndtw-2\charscalex100 en portador. \par\pard\ql \li170
1\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\
sb0\sl-230\slmult0 \par\pard\ql\li1701\sb37\sl-230\slmult0 \up0 \expndtw0\charsc
alex107 CONTAGIO \par\pard\qj \li1701\ri1529\sb234\sl-250\slmult0 \up0 \expndtw1\charscalex100 La forma ms comn de transmisin es mediante el contacto directo entr
e animales \up0 \expndtw-1\charscalex100 infectados (en la fase aguda o portador
es) y animales sanos, a travs de exudados \up0 \expndtw-3\charscalex100 (secrecio
nes, excreciones, semen, sangre). \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\p
ard\ql\li1701\sb17\sl-230\slmult0 \up0 \expndtw-3\charscalex100 El movimiento de
animales es la principal forma de diseminacin. \par\pard\ql \li1701\sb0\sl-230\s
lmult0 \par\pard\ql\li1701\sb20\sl-230\slmult0 \up0 \expndtw-2\charscalex100 Exi
sten otras importantes vas de contagio indirecto de esta enfermedad: \par\pard\qj
\li2061\sb0\sl-240\slmult0 \par\pard\qj\li2061\ri1533\sb22\sl-240\slmult0\tx242
1 \up0 \expndtw0\charscalex103 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersu
b\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Personas que entran en las explotac
iones: veterinarios, comerciantes de \line\tab \up0 \expndtw-3\charscalex100 por
cinos, etc. \par\pard\qj \li2061\ri1523\sb0\sl-240\slmult0\tx2421 \up0 \expndtw1\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20
\ul0\nosupersub\cf4\f5\fs20 Contacto indirecto a travs de materiales cont
aminados: herramientas, \line\tab \up0 \expndtw-2\charscalex100 vehculos, ropa,
calzado, instrumentos, equipo quirrgico, etc. \par\pard\ql \li2061\sb9\sl-230\slm
ult0 \up0 \expndtw-1\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosup
ersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Insectos y roedores. \par\pard\
sect\sectd\fs24\paperw11900\paperh16840{\shp
{\*\shpinst\shpleft5320\shptop15800\shpright6580\shpbottom16140\shpwr3\shpfblwtx

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\pard\sb0\sl-240{\bkmkstart Pg2}{\bkmkend Pg2}\par\pard\ql \li8139\sb0\sl-184\sl
mult0 \par\pard\ql\li8139\sb0\sl-184\slmult0 \par\pard\ql\li8139\sb0\sl-184\slmu
lt0 \par\pard\ql\li8139\sb115\sl-184\slmult0 \up0 \expndtw-2\charscalex100 \ul0\
nosupersub\cf1\f2\fs16 PESTE PORCINA CLSICA \par\pard\ql \li2061\sb0\sl-230\slmul
t0 \par\pard\ql\li2061\sb88\sl-230\slmult0 \up0 \expndtw-3\charscalex100 \ul0\no
supersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\
fs20 Inseminacin artificial con semen contaminado. \par\pard\ql \li2061\sb30\sl
-230\slmult0 \up0 \expndtw-2\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\u
l0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Alimentos para los cerd
os a base de desechos insuficientemente cocidos. \par\pard\ql \li2061\sb10\sl-23
0\slmult0 \up0 \expndtw-1\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\
nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Purines contaminados. \par
\pard\qj \li2061\ri1523\sb2\sl-240\slmult0\tx2421 \up0 \expndtw0\charscalex100 \
ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\c
f4\f5\fs20 Transmisin de madres portadoras inaparentes a sus lechones (a travs d
e \line\tab \up0 \expndtw-3\charscalex100 la barrera placentaria) o a otros anim
ales adultos susceptibles. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\
li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li
1701\sb59\sl-230\slmult0 \up0 \expndtw0\charscalex107 SNTOMAS Y LESIONES \par\par
d\qj \li1701\sb0\sl-240\slmult0 \par\pard\qj\li1701\ri1474\sb2\sl-240\slmult0 \u
p0 \expndtw-2\charscalex100 Periodo de incubacin entre 2-14 das y cuadro h
emorrgico generalizado que \line \up0 \expndtw-2\charscalex100 depende del esta
do inmune, la edad del animal afectado y la virulencia de la cepa. \par\pard\li2
061\sb0\sl-230\slmult0\par\pard\li2061\sb37\sl-230\slmult0\fi0\tx2421 \up0 \expn
dtw0\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\tab \up0 \expndtw0\charsc
alex100 \ul0\nosupersub\cf4\f5\fs20 Forma sobreaguda o hiperaguda\par\pard\li206
1\sb0\sl-230\slmult0\par\pard\li2061\sb26\sl-230\slmult0\fi720\tx3141 \up0 \expn
dtw0\charscalex100 \ul0\nosupersub\cf6\f7\fs20 -\tab \up0 \expndtw0\charscalex10
0 \ul0\nosupersub\cf4\f5\fs20 Sntomas: morbilidad y mortalidad muy elevadas, leta
rgia y muerte\par\pard\li2061\sb14\sl-230\slmult0\fi1080 \up0 \expndtw0\charscal
ex100 entre 24-48 horas tras la infeccin.\par\pard\li2061\sb12\sl-230\slmult0\fi7
20\tx3141 \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf6\f7\fs20 -\tab \up0 \e
xpndtw0\charscalex100 \ul0\nosupersub\cf4\f5\fs20 Lesiones: inespecficas, conge
stin de pulmones, hgado y tracto\par\pard\li2061\sb14\sl-230\slmult0\fi1080 \
up0 \expndtw0\charscalex100 gastrointestinal.\par\pard\li2061\sb0\sl-230\slmult0
\par\pard\li2061\sb26\sl-230\slmult0\fi0\tx2421 \up0 \expndtw0\charscalex100 \ul
0\nosupersub\cf5\f6\fs20 \u8226?\tab \up0 \expndtw0\charscalex100 \ul0\nosupersu

b\cf4\f5\fs20 Forma aguda\par\pard\li2061\sb0\sl-230\slmult0\par\pard\li2061\sb2

6\sl-230\slmult0\fi720\tx3141 \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf6\f
7\fs20 -\tab \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf4\f5\fs20 Sntomas: fi
ebre, anorexia, letargia, hemorragias y cianosis en la\par\pard\li2061\sb12\sl-2
30\slmult0\fi1080 \up0 \expndtw0\charscalex100 piel, conjuntivitis, estreimie
nto transitorio seguido de diarrea,\par\pard\li2061\sb14\sl-230\slmult0\
fi1080 \up0 \expndtw0\charscalex100 vmitos ocasionales, disnea, tos, ataxia,
convulsiones. Mortalidad\par\pard\li2061\sb13\sl-230\slmult0\fi1080 \up0 \expn
dtw0\charscalex100 prxima al 100 %.\par\pard\li2061\sb13\sl-230\slmult0\fi720\tx3
141 \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf6\f7\fs20 -\tab \up0 \expndtw
0\charscalex100 \ul0\nosupersub\cf4\f5\fs20 Lesiones: petequias en rganos (riones,
vejiga urinaria, ganglios\par\pard\li2061\sb13\sl-230\slmult0\fi1080 \up0 \expn
dtw0\charscalex100 linfticos, bazo, laringe, etc.), infecciones bacterianas secun
darias.\par\pard\li2061\sb0\sl-230\slmult0\par\pard\li2061\sb26\sl-230\slmult0\f
i0\tx2421 \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\tab \
up0 \expndtw0\charscalex100 \ul0\nosupersub\cf4\f5\fs20 Forma subaguda\par\pard\
li2061\sb0\sl-230\slmult0\par\pard\li2061\sb26\sl-230\slmult0\fi720\tx3141 \up0
\expndtw0\charscalex100 \ul0\nosupersub\cf6\f7\fs20 -\tab \up0 \expndtw0\charsca
lex100 \ul0\nosupersub\cf4\f5\fs20 Sntomas: similares a la forma aguda pero de m
enor intensidad,\par\pard\li2061\sb13\sl-230\slmult0\fi1080 \up0 \expndtw0\chars
calex100 curso ms lento, periodo de incubacin ms prolongado, tasa de\par\pard\li206
1\sb13\sl-230\slmult0\fi1080 \up0 \expndtw0\charscalex100 mortalidad menor del 3
0 %.\par\pard\li2061\sb14\sl-230\slmult0\fi720\tx3141 \up0 \expndtw0\charscalex1
00 \ul0\nosupersub\cf6\f7\fs20 -\tab \up0 \expndtw0\charscalex100 \ul0\nosupersu
b\cf4\f5\fs20 Lesiones: similares a las de la forma aguda. Son caractersticas las
\par\pard\li2061\sb12\sl-230\slmult0\fi1080 \up0 \expndtw0\charscalex100 lceras b
otonosas o botones pestosos en intestino, reas de necrosis\par\pard\li2061\sb14\s
l-230\slmult0\fi1080 \up0 \expndtw0\charscalex100 circulares y concntricas muy
bien delimitadas, de unos pocos\par\pard\li2061\sb12\sl-230\slmult0\fi1080
\up0 \expndtw0\charscalex100 milmetros a varios centmetros de dimetro.\par\pard\li
2061\sb0\sl-230\slmult0\par\pard\li2061\sb26\sl-230\slmult0\fi0\tx2421 \up0 \exp
ndtw0\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\tab \up0 \expndtw0\chars
calex100 \ul0\nosupersub\cf4\f5\fs20 Forma crnica\par\pard\li2061\sb0\sl-230\slmu
lt0\par\pard\li2061\sb26\sl-230\slmult0\fi720\tx3141 \up0 \expndtw0\charscalex10
0 \ul0\nosupersub\cf6\f7\fs20 -\tab \up0 \expndtw0\charscalex100 \ul0\nosupersub
\cf4\f5\fs20 Sntomas: curso muy lento, periodos prolongados e intermitentes de\pa
r\pard\li2061\sb14\sl-230\slmult0\fi1080 \up0 \expndtw0\charscalex100 fiebre y
viremia, postracin, apetito irregular, retraso del\par\pard\li2061\s
b14\sl-230\slmult0\fi1080 \up0 \expndtw0\charscalex100 crecimiento,
tos,
d
iarrea,
aborto,
infecciones
bacterianas\par\pard\li2061\sb12\sl-230\slm
ult0\fi1080 \up0 \expndtw0\charscalex100 secundarias, aparente recuperacin con re
cada y muerte.\par\pard\li2061\sb14\sl-230\slmult0\fi720\tx3141 \up0 \expndtw0\ch
arscalex100 \ul0\nosupersub\cf6\f7\fs20 -\tab \up0 \expndtw0\charscalex100 \ul0\
nosupersub\cf4\f5\fs20 Lesiones: enteritis difteroide difusa, lceras botonosas en
ciego e\par\pard\li2061\sb12\sl-230\slmult0\fi1079 \up0 \expndtw0\charscalex100
intestino grueso.\par\pard\li2061\sb0\sl-230\slmult0\par\pard\li2061\sb26\sl-23
0\slmult0\fi0\tx2421 \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u
8226?\tab \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf4\f5\fs20 Forma transpl
acentaria\par\pard\li2061\sb0\sl-230\slmult0\par\pard\li2061\sb26\sl-230\slmult0
\fi719\tx3141 \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf6\f7\fs20 -\tab \up
0 \expndtw0\charscalex100 \ul0\nosupersub\cf4\f5\fs20 Lechones
nacidos
mue
rtos
o
dbiles,
momificaciones
y\par\pard\qj \li3141\ri1527\sb0\sl-240
\slmult0 \up0 \expndtw0\charscalex100 malformaciones fetales, infeccin congnita pe
rsistente en lechones \up0 \expndtw-3\charscalex100 que sobreviven, convirtindose
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\pard\sb0\sl-240{\bkmkstart Pg3}{\bkmkend Pg3}\par\pard\ql \li8139\sb0\sl-184\sl
mult0 \par\pard\ql\li8139\sb0\sl-184\slmult0 \par\pard\ql\li8139\sb0\sl-184\slmu
lt0 \par\pard\ql\li8139\sb115\sl-184\slmult0 \up0 \expndtw-2\charscalex100 \ul0\
nosupersub\cf1\f2\fs16 PESTE PORCINA CLSICA \par\pard\ql \li1701\sb0\sl-230\slmul
t0 \par\pard\ql\li1701\sb88\sl-230\slmult0 \up0 \expndtw0\charscalex105 \ul0\nos
upersub\cf4\f5\fs20 EFECTOS \par\pard\qj \li1701\sb0\sl-240\slmult0 \par\pard\qj
\li1701\ri1473\sb22\sl-240\slmult0 \up0 \expndtw-2\charscalex100 Se producen pr
didas de animales como consecuencia de la alta morbilidad y \up0 \expnd
tw-3\charscalex100 mortalidad (50-90 %) y en reproductividad. \par\pard\qj \li17

01\ri1512\sb236\sl-246\slmult0 \up0 \expndtw-2\charscalex100 Produce un alto

impacto econmico en los pases afectados y causa prdidas \line \up0 \expndtw
0\charscalex100 significantes debido al sacrificio e inmovilizacin de animales, a
l cierre de fronteras \line \up0 \expndtw0\charscalex102 a cerdos vivos, carne f
resca, productos elaborados con carne porcina no tratada, \line \up0 \expndtw-2\
charscalex100 semen y embriones porcinos, y a los grandes costos de control y er
radicacin. \par\pard\qj \li1701\ri1524\sb239\sl-240\slmult0 \up0 \expndtw0\charsc
alex100 No tiene repercusin en la salud pblica, ya que no se transmite al ser huma
no. La \line \up0 \expndtw-2\charscalex100 ingestin de productos contaminados no
supone ningn riesgo para las personas. \par\pard\ql \li1701\sb0\sl-230\slmult0 \p
ar\pard\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par
\pard\ql\li1701\sb59\sl-230\slmult0 \up0 \expndtw0\charscalex107 DIAGNSTICO \par\
pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb20\sl-230\slmult0 \up0
\expndtw-3\charscalex100 Diagnstico clnico \par\pard\qj \li2409\ri1528\sb234\sl-25
0\slmult0 \up0 \expndtw0\charscalex103 Cuadro hemorrgico generalizado. Existen fo
rmas ms solapadas o poco \up0 \expndtw0\charscalex105 aparentes, y la sintomatolo
ga y lesiones pueden confundirse con las de \up0 \expndtw-3\charscalex100 otras e
nfermedades del cerdo. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li17
01\sb17\sl-230\slmult0 \up0 \expndtw-3\charscalex100 Diagnstico laboratorial \par
\pard\qj \li2407\ri1522\sb234\sl-250\slmult0 \up0 \expndtw0\charscalex100 El dia
gnstico de laboratorio es imprescindible debido a la gran variedad de \up0 \expnd
tw-2\charscalex100 sntomas y lesiones que puede presentar la enfermedad y
que pueden \up0 \expndtw-2\charscalex100 confundirse con otras enfermedades h
emorrgicas del cerdo: \par\pard\ql \li2757\ri1533\sb239\sl-240\slmult0\tx3117 \up
0 \expndtw-3\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf
6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Anlisis virolgicos: deteccin del virus
, sus antgenos o el cido \line\tab \up0 \expndtw-4\charscalex100 nucleico del
virus. \par\pard\ql \li2757\ri1526\sb232\sl-250\slmult0\tx3117\tx3117 \up0 \exp
ndtw-2\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\f
s20 \ul0\nosupersub\cf4\f5\fs20 Anlisis serolgicos: deteccin de los anticue
rpos que produce el \line\tab \up0 \expndtw-1\charscalex100 cuerpo del animal
infectado frente al virus. Es de gran utilidad para \line\tab \up0 \expndtw-3\c
harscalex100 comprobar la presencia o no de zonas libres y no vacunadas. \par\pa
rd\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\par
d\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb37\sl-230\slmult0 \up0 \exp
ndtw0\charscalex107 TRATAMIENTO \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\par
d\ql\li1701\sb40\sl-230\slmult0 \up0 \expndtw-3\charscalex100 No existe tratamie
nto. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmu
lt0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb40\sl-230\slmul
t0 \up0 \expndtw0\charscalex109 PREVENCIN \par\pard\ql \li1701\sb0\sl-230\slmult0
\par\pard\ql\li1701\sb20\sl-230\slmult0 \up0 \expndtw-3\charscalex100 En los pas
es afectados \par\pard\qj \li1701\sb0\sl-240\slmult0 \par\pard\qj\li1701\ri1523\
sb22\sl-240\slmult0 \up0 \expndtw-2\charscalex100 La eliminacin de la enfermedad
en los pases afectados se basa en un programa de \up0 \expndtw-2\charscalex100 co
ntrol con vacunacin y posterior erradicacin. \par\pard\ql \li1701\sb0\sl-230\slmul
t0 \par\pard\ql\li1701\sb19\sl-230\slmult0 \up0 \expndtw-2\charscalex100 En los
pases libres de la enfermedad \par\pard\qj \li1701\sb0\sl-240\slmult0 \par\pard\q
j\li1701\ri1534\sb22\sl-240\slmult0 \up0 \expndtw-1\charscalex100 En los pases li
bres de la enfermedad o en los que est progresando la erradicacin, \line \up0 \exp
ndtw-1\charscalex100 la vacunacin est generalmente prohibida. Para prevenir la ent
rada del virus se ha \line \up0 \expndtw-1\charscalex100 de realizar una estrict
a profilaxis sanitaria, con medidas de bioseguridad y sistemas \par\pard\sect\se
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\pard\sb0\sl-240{\bkmkstart Pg4}{\bkmkend Pg4}\par\pard\ql \li8139\sb0\sl-184\sl
mult0 \par\pard\ql\li8139\sb0\sl-184\slmult0 \par\pard\ql\li8139\sb0\sl-184\slmu
lt0 \par\pard\ql\li8139\sb115\sl-184\slmult0 \up0 \expndtw-2\charscalex100 \ul0\
nosupersub\cf1\f2\fs16 PESTE PORCINA CLSICA \par\pard\qj \li1701\sb0\sl-260\slmul
t0 \par\pard\qj\li1701\ri1535\sb34\sl-260\slmult0 \up0 \expndtw0\charscalex100 \
ul0\nosupersub\cf4\f5\fs20 eficaces de notificacin de enfermedades y sistemas de
registro e identificacin de \line \up0 \expndtw-2\charscalex100 cerdos. \par\pard
\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb15\sl-230\slmult0 \up0 \exp
ndtw-3\charscalex100 Medidas que deben tomarse en los focos: \par\pard\qj \li206
1\sb0\sl-240\slmult0 \par\pard\qj\li2061\ri1525\sb2\sl-240\slmult0\tx2421 \up0 \
expndtw0\charscalex102 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7
\fs20 \ul0\nosupersub\cf4\f5\fs20 Sacrificar todos los cerdos en las 24 horas
posteriores al diagnstico. Si es \line\tab \up0 \expndtw-2\charscalex100 necesar
io, crear un \u8220?colchn sanitario\u8221? (sacrificio de animales sanos). \par\
pard\ql \li2061\ri1526\sb20\sl-240\slmult0\tx2421\tx2421 \up0 \expndtw0\charscal
ex103 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosup
ersub\cf4\f5\fs20 Establecer una zona de proteccin alrededor del foco, con proh
ibicin del \line\tab \up0 \expndtw0\charscalex100 movimiento de animales, y una z
ona de vigilancia en la que se efectuarn \line\tab \up0 \expndtw-3\charscalex100
controles clnicos y serolgicos. \par\pard\ql \li2061\sb9\sl-230\slmult0 \up0 \expn
dtw-3\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs
20 \ul0\nosupersub\cf4\f5\fs20 Eliminar canales, camas, medicamentos, pienso
sobrante, etc. \par\pard\qj \li2061\ri1534\sb2\sl-240\slmult0\tx2421 \up0 \expnd
tw0\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20
\ul0\nosupersub\cf4\f5\fs20 Limpiar y desinfectar a fondo la granja, incluid
a la entrada, aparcamientos, \line\tab \up0 \expndtw-4\charscalex100 etc. \par\p
ard\ql \li2061\sb9\sl-230\slmult0 \up0 \expndtw0\charscalex102 \ul0\nosupersub\c
f5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Des
ratizar. \par\pard\ql \li2061\sb30\sl-230\slmult0 \up0 \expndtw-2\charscalex100
\ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\
cf4\f5\fs20 Cerrar ventanas y puertas. \par\pard\ql \li2061\sb10\sl-230\slmult
0 \up0 \expndtw-2\charscalex100 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupers
ub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 No sacar purines hasta pasados 45
das. \par\pard\ql \li2061\sb10\sl-230\slmult0 \up0 \expndtw-2\charscalex100 \ul0\
nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f
5\fs20 Identificar la zona infectada, con control de los desplazamientos de po
rcinos. \par\pard\ql \li2061\sb10\sl-230\slmult0 \up0 \expndtw-2\charscalex100 \
ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\c
f4\f5\fs20 Investigar fuentes posibles y posibilidades de propagacin de la infe
ccin. \par\pard\ql \li2061\sb10\sl-230\slmult0 \up0 \expndtw-3\charscalex100 \ul0
\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\
f5\fs20 Marcar la explotacin como afectada de forma visible y clara. \par\pard\
ql \li2061\sb10\sl-230\slmult0 \up0 \expndtw-2\charscalex100 \ul0\nosupersub\cf5

\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Prohi

bir la entrada a cualquier persona. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par
\pard\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\p
ard\ql\li1701\sb60\sl-230\slmult0 \up0 \expndtw0\charscalex105 CURIOSIDADES \par
\pard\qj \li2061\sb0\sl-240\slmult0 \par\pard\qj\li2061\ri1525\sb2\sl-240\slmult
0\tx2421 \up0 \expndtw0\charscalex106 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\no
supersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 La peste porcina clsica fue d
escrita por vez primera en Ohio (EE.UU), a \line\tab \up0 \expndtw-2\charscalex1
00 principios del siglo XIX, y apareci en Europa por primera vez en 1862. \par\pa
rd\ql \li2061\sb0\sl-243\slmult0 \par\pard\ql\li2061\ri1521\sb15\sl-243\slmult0\
tx2421\tx2421\tx2421\tx2421\tx2421\tx2421 \up0 \expndtw-1\charscalex100 \ul0\nos
upersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\f
s20 Entre las mltiples medidas de bioseguridad se incluyen mantener al da un \li
ne\tab \up0 \expndtw-1\charscalex100 libro de visitas, no permitir la entrada a
la explotacin de vehculos salvo si \line\tab \up0 \expndtw0\charscalex100 estn limp
ios y desinfectados, la utilizacin de botas de goma o calzas de \line\tab \up0 \e
xpndtw-2\charscalex100 plstico, el control de los animales domsticos (insectos, pja
ros y ratas), no \line\tab \up0 \expndtw-3\charscalex100 compartir materiales o
utensilios entre granjas, la limpieza y desinfeccin de \line\tab \up0 \expndtw-1\
charscalex100 suelos y paredes, disponer de fosas de cadveres en la misma explota
cin, \line\tab \up0 \expndtw-4\charscalex100 etc. \par\pard\ql \li2061\ri1534\sb2
40\sl-240\slmult0\tx2421\tx2421 \up0 \expndtw0\charscalex100 \ul0\nosupersub\cf5
\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 El vi
rus de la peste porcina clsica conserva su carcter infeccioso durante \line\tab \u
p0 \expndtw-3\charscalex100 meses en los productos derivados del cerdo (carne cr
uda, tocino, embutidos, \line\tab \up0 \expndtw-4\charscalex100 etc.). Por eje
mplo, puede mantenerse durante \up0 \expndtw-3\charscalex100 1.500 das en l
a carne \par\pard\ql \li2421\sb9\sl-230\slmult0 \up0 \expndtw-3\charscalex100 c
ongelada. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230
\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb60\sl-230\
slmult0 \up0 \expndtw0\charscalex106 QU HACE EL CReSA ANTE LA PESTE PORCINA CLSICA
\par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0
\par\pard\ql\li1701\sb30\sl-230\slmult0 \up0 \expndtw-3\charscalex100 Unidad de
Enfermedades Vricas \par\pard\ql \li2061\sb0\sl-240\slmult0 \par\pard\ql\li2061\r
i1473\sb22\sl-240\slmult0\tx2421\tx2421\tx2421 \up0 \expndtw0\charscalex103 \ul0
\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\
f5\fs20 Servicio de diagnstico: anlisis virolgicos (confirmacin de las muestras \l
ine\tab \up0 \expndtw-1\charscalex100 positivas y/o dudosas con ELISA de deteccin
de anticuerpos y aislamiento y \line\tab \up0 \expndtw-2\charscalex100 deteccin
de virus) por encargo del servicio del Departamento de \line\t
ab \up0 \expndtw-5\charscalex100 Agricultura, Alimentacin y Accin Rural \u
p0 \expndtw0\charscalex102 (DAR) de la Generalitat de \par\pard\ql \li2421\s
b9\sl-230\slmult0 \up0 \expndtw-2\charscalex100 Catalua. \par\pard\ql \li2061\sb0
\sl-240\slmult0 \par\pard\ql\li2061\ri1514\sb22\sl-240\slmult0\tx2421\tx2421 \up
0 \expndtw0\charscalex107 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6
\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Estudios virolgicos: estudios de biologa m
olecular para esclarecer la \line\tab \up0 \expndtw-2\charscalex100 interaccin
hospedador-virus, identificar nuevas dianas para su uso \line\tab \u
p0 \expndtw-3\charscalex100 teraputico o preventivo y descubrir marcadores para e
l diagnstico. \par\pard\sect\sectd\fs24\paperw11900\paperh16840{\shp
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\pard\sb0\sl-240{\bkmkstart Pg5}{\bkmkend Pg5}\par\pard\ql \li8139\sb0\sl-184\sl
mult0 \par\pard\ql\li8139\sb0\sl-184\slmult0 \par\pard\ql\li8139\sb0\sl-184\slmu
lt0 \par\pard\ql\li8139\sb115\sl-184\slmult0 \up0 \expndtw-2\charscalex100 \ul0\
nosupersub\cf1\f2\fs16 PESTE PORCINA CLSICA \par\pard\ql \li2061\sb0\sl-240\slmul
t0 \par\pard\ql\li2061\sb0\sl-240\slmult0 \par\pard\ql\li2061\ri1531\sb90\sl-240
\slmult0\tx2421\tx2421 \up0 \expndtw0\charscalex103 \ul0\nosupersub\cf5\f6\fs20
\u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20 Desarrollo de
nuevas vacunas: desarrollo de nuevas estrategias de \line\tab \up0 \expn
dtw-1\charscalex100 control, que incluyen el desarrollo de una nueva vacuna ms ef
icaz que las \line\tab \up0 \expndtw-2\charscalex100 ya existentes en el mercado
. \par\pard\ql \li2061\ri1520\sb232\sl-250\slmult0\tx2421\tx2421 \up0 \expndtw0\
charscalex107 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \u
l0\nosupersub\cf4\f5\fs20 Asesora y divulgacin cientfica: asesora cientfica al sect
or pblico y \line\tab \up0 \expndtw-2\charscalex100 privado, participacin como
autores y/o revisores en publicaciones \line\tab \up0 \expndtw-3\char
scalex100 especializadas y elaboracin de material tcnico sobre la enfermedad. \par
\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\slmult0 \par\
pard\ql\li1701\sb27\sl-230\slmult0 \up0 \expndtw-3\charscalex100 Unidad de Inmun
ologa \par\pard\ql \li2061\ri1525\sb237\sl-246\slmult0\tx2421\tx2421\tx2421 \up0
\expndtw0\charscalex111 \ul0\nosupersub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f
7\fs20 \ul0\nosupersub\cf4\f5\fs20 Desarrollo de nuevas estrategias vacunales
e inmunomoduladoras: \line\tab \up0 \expndtw-1\charscalex100 estudio de fac
tores moleculares y mecanismos de transmisin y \line\tab \up0 \expndt
w0\charscalex101 patogenicidad y mecanismos inmunolgicos para el desarrollo de nu
evas \line\tab \up0 \expndtw-3\charscalex100 estrategias vacunales e inmunomodul
adoras. \par\pard\ql \li1701\sb0\sl-230\slmult0 \par\pard\ql\li1701\sb0\sl-230\s
lmult0 \par\pard\ql\li1701\sb28\sl-230\slmult0 \up0 \expndtw-3\charscalex100 Uni
dad de Epidemiologa \par\pard\ql \li2061\sb0\sl-240\slmult0 \par\pard\ql\li2061\r
i1519\sb22\sl-240\slmult0\tx2421\tx2421 \up0 \expndtw0\charscalex102 \ul0\nosupe
rsub\cf5\f6\fs20 \u8226?\ul0\nosupersub\cf6\f7\fs20 \ul0\nosupersub\cf4\f5\fs20
Estudios epidemiolgicos: estudios descriptivos y analticos, modelizacin \line\ta
b \up0 \expndtw-1\charscalex100 y anlisis de riesgo y asesoramiento en el
diseo, implementacin y \line\tab \up0 \expndtw-2\charscalex100 evaluacin de los
programas de vigilancia y control de la enfermedad. \par\pard\sect\sectd\fs24}