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  • Pathophys BURN

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    paupaulala
    6K visualizações2 páginas
    Cell lysis Hemolysis Hyperkalemia Major Burns > 30% BSA Capillary permeability Sodium, Water and Protein shift from IVS to ITS Loss of skin barrier Possible inhalation injury Thermoregulation problems Inflammatory response Hemoglobin / myoglobin in urine Concentration of blood cells Impaired immune response Hyponatremia blood viscosity Circulating blood volume (up to 50%) shock (hypovol) Massive stress response, sympathetic nervous system

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    Cell lysis Hemolysis Hyperkalemia Major Burns > 30% BSA Capillary permeability Sodium, Water and Protein shift from IVS to ITS Loss of skin barrier Possible inhalation injury Thermoregulation problems Inflammatory response Hemoglobin / myoglobin in urine Concentration of blood cells Impaired immune response Hyponatremia blood viscosity Circulating blood volume (up to 50%) shock (hypovol) Massive stress response, sympathetic nervous system

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    Attribution Non-Commercial (BY-NC)
    Baixe no formato DOC, PDF, TXT ou leia online no Scribd
    Sinalizar o conteúdo como inadequado
    6K visualizações2 páginas

    Pathophys BURN

    Enviado por

    paupaulala
    Cell lysis Hemolysis Hyperkalemia Major Burns > 30% BSA Capillary permeability Sodium, Water and Protein shift from IVS to ITS Loss of skin barrier Possible inhalation injury Thermoregulation problems Inflammatory response Hemoglobin / myoglobin in urine Concentration of blood cells Impaired immune response Hyponatremia blood viscosity Circulating blood volume (up to 50%) shock (hypovol) Massive stress response, sympathetic nervous system

    Direitos autorais:

    Attribution Non-Commercial (BY-NC)
    Baixe no formato DOC, PDF, TXT ou leia online no Scribd
    Sinalizar o conteúdo como inadequado
    de 2

    PATHOPHYSIOLOGY OF BURN INJURY

    Major Burns Loss of skin


    barrier
    Cell lysis > 30% BSA
    Possible
    inhalation
    Hemolysis Hyperkalemia injury Thermo-
    ↑ Capillary regulation
    Inflammatory
    permeability response
    problems
    Hemoglobin/
    myoglobin in Sodium, Water
    urine & Protein shift Impaired
    ↑Concentration immune
    from IVS to ITS
    of blood cells response
    Hyponatremia
    ↓ Circulating
    blood volume Hypoxemia
    ↑ Blood (up to 50%)
    viscosity
    Shock (hypovol)

    ↑ Myocardial Massive stress response, sympathetic ↓ Blood


    depressant factor nervous system activation
    pressure

    Adrenal corticoid hormones &


    catecholamine release

    Hyperglycemia;↑Catabolism; Risk for


    Peripheral
    vasoconstriction Tachycardia Curlin’s ulcer; ↑ Metabolism (after burn
    shock resolves)
    Afterload

    Dec.
    Cardiac
    output

    Dec. Tissue
    perfusion

    Dec. Renal Dec. GI Anaerobic Tissue Cellular


    blood flow blood flow metabolism damage dysfunction

    Risk of acute Risk of Metabolic Potential tissue Cell


    renal failure ileus acidosis necrosis swelling

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