HEMARATE FA Hemarate FA consists of Folic Acid, Iron (Ferrous Sulfate), Vitamin B12, Vitamin B6.

Folic Acid - A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Hemarate FA (Folic Acid) is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. Indication: For treatment of Hemarate FA (Folic Acid) deficiency, megaloblastic anemia and in anemias of nutritional supplements, pregnancy, infancy, or childhood. Hemarate FA (Folic Acid), a water-soluble B-complex vitamin, is found in foods such as liver, kidneys, yeast, and leafy, green vegetables. Hemarate FA (Folic Acid) is used to diagnose folate deficiency and to treat topical sprue and megaloblastic and macrocytic anemias, hematologic complications resulting from a deficiency in folic acid. Iron (Ferrous Sulfate) - A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of Hemarate FA (Iron (Ferrous Sulfate)) stores may result in iron-deficiency anemia. Hemarate FA (Iron (Ferrous Sulfate)) is used to build up the blood in anemia. Indication: Used in preventing and treating iron-deficiency anemia. The major activity of supplemental Hemarate FA (Iron (Ferrous Sulfate)) is in the prevention and treatment of Hemarate FA (Iron (Ferrous Sulfate)) deficiency anemia. Hemarate FA (Iron (Ferrous Sulfate)) has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities. Vitamin B12 Pharmacological action Hemarate FA (Vitamin B12) refers to a group of water-soluble vitamins. It has high biological activity. Hemarate FA (Vitamin B12) is necessary for normal hematopoiesis (promotes maturation of erythrocytes). Involved in the processes of transmethylation, hydrogen transport, synthesis of methionine, nucleic acids, choline, creatine. Contributes to the accumulation in erythrocytes of compounds containing sulfhydryl groups. Has a beneficial effect on liver function and the nervous system. Activates the coagulation of blood in high doses causes an increase in the activity of thromboplastin and prothrombin. Pharmacokinetics After oral administration Hemarate FA (Vitamin B12) absorbed from the gastrointestinal tract. Metabolized in the tissues, becoming a co-enzyme form - adenosylcobalamin which is the active form of cyanocobalamin. Excreted in bile and urine. Why is Hemarate FA (Vitamin B12) prescribed? Anemia due to B12-deficiency conditions; in the complex therapy for iron and posthemorrhagic anemia; aplastic anemia caused by toxic substances and drugs; liver disease (hepatitis, cirrhosis); funicular myelosis; polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis; children cerebral palsy, Down syndrome, peripheral nerve injury; skin diseases (psoriasis, photodermatosis, herpetiformis dermatitis, neurodermatitis); to prevent and treat symptoms of deficiency of Hemarate FA (Vitamin B12) (including the application of biguanide, PASA, vitamin C in high doses); radiation sickness. Dosage and administration Hemarate FA (Vitamin B12) is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with Hemarate FA (Vitamin B12) deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute posthemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days. In diseases of the central and peripheral nervous system and

neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Hemarate FA (Vitamin B12) is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days. When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days. Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day. When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms. In radiation sickness, diabetic neuropathy, sprue by 60-100 mcg daily for 20-30 days. When deficiency of Hemarate FA (Vitamin B12) to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually. Hemarate FA (Vitamin B12) side effects, adverse reactions CNS: rarely - a state of arousal. Cardiovascular system: rarely - pain in the heart, tachycardia. Allergic reactions: rarely - urticaria. Hemarate FA (Vitamin B12) contraindications Thromboembolism, erythremia, erythrocytosis, increased sensitivity to cyanocobalamin. Hemarate FA (Vitamin B12) using during pregnancy and breastfeeding Cyanocobalamin can be used in pregnancy according to prescriptions. Special instructions When stenocardia should be used with caution in a single dose of Hemarate FA (Vitamin B12) 100 mcg. During treatment should regularly monitor the blood picture and coagulation. It is unacceptable to enter in the same syringe with cyanocobalamin solutions of thiamine and pyridoxine. Hemarate FA (Vitamin B12) drug interactions In an application of Hemarate FA (Vitamin B12) with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma. In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut. In an Hemarate FA (Vitamin B12) application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut. Cyanocobalamin may exacerbate allergic reactions caused by thiamine. When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia. Pharmaceutical incompatibility Contained in the molecule of cyanocobalamin cobalt ion contributes to the destruction of ascorbic acid, thiamine bromide, riboflavin in one solution. Pharmaceutical active ingredients containing related brand and generic drugs, medications or other health care products: Folic Acid Iron (Ferrous Sulfate) Vitamin B12 Vitamin B6 Hemarate FA available forms, composition, doses: Tablets; Oral; Folic Acid 600 mcg; Iron (Ferrous Sulfate) 60 mg; Vitamin B12 25 mcg; Vitamin B6 20 mg Hemarate FA destination | category: Human: Antianemics Vitamins and minerals (pre and post natal) Indications and usages, anatomical therapeutic chemical and diseases classification codes: B03AE02 - Iron, multivitamins and Folic Acid Pharmaceutical companies, researchers, developers, manufacturers, distributors and suppliers: BioFemme United Laboratories More: http://www.idruginfo.com/?cat=drug&s=Hemarate%20FA&ingredient=Folic%20Acid/Iron%20(Ferrous% 20Sulfate)/Vitamin%20B12/Vitamin%20B6 More: http://www.idruginfo.com/?cat=drug&s=Hemarate%20FA&ingredient=Folic%20Acid/Iron%20( Ferrous%20Sulfate)/Vitamin%20B12/Vitamin%20B6