Brand name: Cyklokapron

Generic name: Tranexamic acid

Indication: This medication is used for short-term control of bleeding in hemophiliacs,
including dental extraction procedures.
Drug classification: Hemostatic, systemic; anti-fibrimolytic agent
Mechanism of Action: This acts against breakdown of clots (by inhibiting or stopping
plasminogen activation and fibrinolysis), and so it is useful in stopping severe
blood loss as it increases clot formation.
Dosage: IV, Immediately before surgery, 10 mg/kg; then, after surgery, PO, 25 mg/kg
t.i.d.-q.i.d. for 2-8 days. Alternative regimen: PO, 25 mg/kg t.i.d.-q.i.d. one day
prior to surgery.
Special Precautions: Before using this drug, tell your doctor your medical history,
including: any allergies, history of blood clots or bleeding, eye problems
(retina/color vision), kidney disease, head injury (subarachnoid hemorrhage).
Tell your doctor if you are pregnant before using this drug. This drug is excreted
into human milk. Consult your doctor before breast-feeding.
Pregnancy risk category: C
Adverse reaction: Nausea, vomiting, diarrhea might occur. If these persist or worsen,
notify your doctor promptly. Very unlikely but report promptly: vision changes,
dizziness.
Contraindications: Subarachnoid hemorrhage, acquired defective color vision.
Form: Tablets; syrup (for pediatric use)
Nursing Responsibilities:
 Assess baseline BP and pulse before starting IV, patient frequently for
hypotension during IV infusion which may indicate the infusion is to fast. Slow
the IV and repot to the physician.
 Observe patient for signs and symptoms of thrombosis, such as leg pain,
respiratory distress, o chest pain and report.
 Anticipate reduced dosage in patients with impaired renal function.
 Stress the importance of opthalmological examinations at regular intervals
during therapy.