Chapter 8 (part2)

Karbohidrat: oligo- dan

polisakarida

CH2OH

Glycosidic
Linkage

CH2OH
hemiacetal

OH

OH
OH

OH

OH
OH

alcohol

OH

Hydrolysis
H 2O

H 2O

Condensation
CH2OH
O

CH2OH
acetal

OH

OH

OH
O

OH
OH

OH
glycosidic linkage

OH

Disakarida
CH2OH
H

CH2OH

O H
OH

O
OH

OH

maltose

H
H

OH

O
OH

O H
OH

H
OH

lactose

CH2OH
OH
H

OH
O

sucrose

OH
OH

CH2OH
O
H
OH

CH2OH
OH

CH2OH
H

O OH
OH

O
H

H
H

OH

(b-D-glucosyl-(1->4)-b-D-glucopyranose)

CH2OH
H

OH
H

OH

(a-D-glucosyl-(1->4)-b-D-glucopyranose)

O OH
OH

OH

CH2OH

cellobiose

CH2OH

OH

OH

(b-D-galactosyl-(1->4)-b-D-glucopyranose)

(a-D-glucosyl-(1->2)-b-D-fructofuranose)

Oligosakarida yang lebih tinggi

Kelompok oligosakarida digabungkan dalam

banyak struktur obat

Polisakarida

Amilosa dan amilopektin

Yodium mengikat amilum

Glikogen

Dekstran

Selulosa

Selulosa vs Amilosa
amylose

cellulose

Glucose units rotated 180o relative to next residue

Selulosa

Kitin

Kitin vs Selulosa

Glikoprotein

O-linked Glycoproteins

Blood ABO Antigens

Structure of the ABO blood group

carbohydrates,
R merupakan hubungan untuk
protein dalam bentuk dikeluarkan,
sphingolipid dalam bentuk
permukaan sel terikat
terbuka persegi = GlcNAc, terbuka
berlian = galaktosa, diisi persegi =
fucose, diisi berlian = GalNAc, diisi
berlian = asam sialat (NANA)

N-linked Glycoproteins