 Pathophysiology

o A. schematic diagram (book based)

Modifiable factors:
• Inadequate access to toilet facilities
Non-modifiable factors:
• Avoidance of the urge to void
• AGE – UTI is a prevalent • Urinary catheterization
disease among children and
• Fistula between the intestine and
elderly
bladder
• SEX – it has a higher • Inadequate fluid intake
incidence rate with the • Pregnancy, and DM
female gender

Bacterial invasion (i.e. E.coli)

Multiplication of the bacteria – causing

UTI in any part of the urinary tract

Interruption in the normal homeostatic

environment of the urinary tract

Immune response by the body (defense Increased

mechanism of the body to foreign bodies) WBC subsequent to Change in urine
pus formation color

Cytokine and
prostaglandin release

Body induces the

action of the cytokines
and prostaglandins

A
 The body responds by Inflammation of the lining of Irritation of the lining of the
producing physiologic the urinary tract urinary tract
changes aimed at elevating
body temperature.
Narrowed urine passage Urethritis and Spasm of the
dysuria bladder
Fever
Poor emptying of the
bladder
Urinary
incontinence
Frequent urination
and urgency, and
nocturia
 Pathophysiology (Client Centered)

Non-modifiable factor:
• Age – UTI is a prevalent Modifiable factors:
disease among children • Avoidance of the urge to void
• Inadequate fluid intake

Bacterial invasion (i.e. E.coli)

Multiplication of the bacteria – causing

UTI in any part of the urinary tract

Interruption in the normal homeostatic

environment of the urinary tract

Immune response by the body (defense Increased

mechanism of the body to foreign bodies) WBC subsequent to Change in urine
pus formation color
Cytokine and Dec.12
Body induces the
action of the cytokines prostaglandin release
and prostaglandins

The body responds by

producing physiologic Fever
changes aimed at elevating Dec.7
body temperature.