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Computed Tomography (Basics)

Siemens Medical Systems

Source: CTC/CTM
© Siemens AG, 1998
Medical Engineering Group, Computed Tomography
CT Basics 1
The Discovery of X-Rays...

100 years ago,

Wilhelm Conrad Roentgen,

a German scientist,

discovered x-rays...

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Medical Engineering Group, Computed Tomography
CT Basics 2
Look Inside The Human Body...

This allowed people for the


first time to be able to view
the anatomy of the human
body noninvasively

« But anatomic structures were superimposed


« And soft tissue couldn’t be differentiated

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Medical Engineering Group, Computed Tomography
CT Basics 3
CT Broke the Barrier...

In 1972,

two scientists -
Hounsfield and Ambrose-
presented the first
clinical CT image ...

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Medical Engineering Group, Computed Tomography
CT Basics 4
The Human Body Slice by Slice...

So we could
see
tomographic anatomy
&
density differences

♠ But it was time consuming (10 min. / image)

♠ And the resolution needed to be improved


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Medical Engineering Group, Computed Tomography
CT Basics 5
What Does a CT Look Like?

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Medical Engineering Group, Computed Tomography
CT Basics 6
The First Siemens CT Scanner...

SIRETOM (in 1974)


Acquisition time 7 min., image matrix 80x80 pixels,
scan field 25 cm , spatial resolution 1,3 mm (4LP/cm)
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Medical Engineering Group, Computed Tomography
CT Basics 7
The Progress in Image Quality...

SIRETOM SOMATOM Plus 4 UFC


(1974) (1996)
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Medical Engineering Group, Computed Tomography
CT Basics 8
What Does a CT Look Like?
From the outside... Gantry
♣ Gantry
♣ Table
♣ Generator Generator
♣ Console
♣ Computer
Table

Console

Computer

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 9
What Does a CT Look Like?
From the inside...
Tube

♣ Tube
♣ Detector
♣ DAS*

DAS
Detector

* Data Acquisition System


Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 10
How Does CT Work?
X-ray
X-ray generation
generation

Data
Data acquisition
acquisition

Recon
Recon && postprocessing
postprocessing

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 11
Image Generation - The “Slice”
X-rays pass through a collimator therefore only
penetrating an axial layer of the object, called
a "slice"

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CT Basics 12
Image Generation - The “Voxel”
The slice is artificially
divided into small volume
elements called "voxels"
with a square base,
inside which the
attenuation is measured
as a constant value.
And in plane, the picture
elements are called “pixels”
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 13
Image Generation - The “Matrix”
The attenuation of radiation values is measured,
encoded and transferred to a computer.

35 36 34 39 33
31 34 33 35 32
31 78 80 85 90

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 14
CT Image Generation - A/D/A*
The numerical matrix is converted into a black and
white image in a corresponding gray scale.
35 36 34 39 33
31 34 33 35 32
31 78 80 85 90

*Analog - Digital - Analog


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Medical Engineering Group, Computed Tomography
CT Basics 15
Criteria for CT Image Quality

CT Image Quality

Spatial resolution Artifacts

Contrast Detectability

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Medical Engineering Group, Computed Tomography
CT Basics 16
Spatial Resolution...
The ability to resolve High Contrast Objects,
(also called “High Contrast Resolution”)

This is influenced by system geometry,


and determines image definition
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Medical Engineering Group, Computed Tomography
CT Basics 17
Definition...
Image definition means the sharpness of an
object relative to surrounding tissue. It
depends on:
Definition

Image display
Scan time
Operating mode
Algorithm
Slice thickness
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Medical Engineering Group, Computed Tomography
CT Basics 18
Contrast Detectability...
When Small Contrast Differences are crucial
(also called “Low Contrast Resolution”)

This is influenced by image definition & noise

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Medical Engineering Group, Computed Tomography
CT Basics 19
Noise?
Noise is superimposed on the image and results in
a "grainy" impression, as is the case with poor TV
reception.
206 mA 60 mA

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Medical Engineering Group, Computed Tomography
CT Basics 20
Noise...
Image “noise” is determined by the number of
x-ray quanta that reach the detector and then
contribute to the image. It depends on:

Noise

Image display
mAs
Operating mode
kV

Algorithm Patient size

Slice thickness
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Medical Engineering Group, Computed Tomography
CT Basics 21
Artifacts...
The various structures or patterns that appear in a
CT image, but are not found in the original object.

Artifacts
They depend on: ...
Scan time Patient

Slice thickness Operating mode

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Medical Engineering Group, Computed Tomography
CT Basics 22
Influences on CT Image Quality?

CT Image Quality
Patient
System

User

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Medical Engineering Group, Computed Tomography
CT Basics 23
System Efficiency...
100 mAs 100 mAs

The complete system design determines how


efficiently x-rays are finally converted to
electrical signal as the detector output, after
passing through the patient.

The generator, tube, geometry, filtration,


collimation and detector design all play a role.

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Medical Engineering Group, Computed Tomography
CT Basics 24
mAs...
Tube current and scan time, determine dose.

Noise

high Rule
Ruleofofthumb:
thumb:
The noise 1
Thehigher
higherthe
thedose,
dose,
the dose
thelower
lowerthe
thenoise.
noise.

* Noise reduced by factor 1.4


while dose is doubled.

low
mAs
low high
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Medical Engineering Group, Computed Tomography
CT Basics 25
mAs...
Low mAs High mAs

Image 1: Image 2:
Low mAs value - 4 times the mAs value-
high noise level half the noise level
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Medical Engineering Group, Computed Tomography
CT Basics 26
Recommendations for mAs...

In the case of a soft tissue study, it is


most important to keep noise to a minimum
by using higher mAs. The lower the noise
level, the easier it is to recognize structures
with minute differences in density. But for
bone or lung studies, higher mAs is not
necessary.

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 27
Tube Voltage - kV
The dose level, depends very strongly on the
voltage applied to the tube.

kV
kV Relative
Relativedose
dose
Water
140
140 100%
100%
20 cm 120
120 58%
58%
80
80 12%
12%

Source: CTC/CTM
© Siemens AG, 1998
Medical Engineering Group, Computed Tomography
CT Basics 28
Tube Voltage - kV
The higher the voltage, the more the radiation
spectrum is shifted to a higher energy level,
resulting in decreased radiation attenuation. This
is most noticeable in bone and contrast media.
140 kV 80 kV

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 29
Algorithms...
... provide the recipe for mathematical image
calculation
Image definition
Sharp ULTRA HIGH

HIGH

STANDARD

SOFT

Smooth SOFT DETAIL


Noise
low High
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 30
Algorithms

An edge-enhancing (HighRes) algorithm


produces good edge definition, but also a
high noise level, while a smoothing
algorithm produces a low noise level, but
also poorer edge definition. For routine
studies, a standard algorithm is normally
recommended.

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 31
Algorithms
Soft Algorithm HighRes Algorithm

Soft algorithms provide better contrast


detectability with less noise.
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Medical Engineering Group, Computed Tomography
CT Basics 32
Algorithms
Standard Algorithm HighRes Algorithm

HighRes algorithms provide better spatial


resolution, but with more noise.
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Medical Engineering Group, Computed Tomography
CT Basics 33
Selecting Slice Thickness
Selecting a suitable slice thickness is a balance
between edge definition and noise because of
their mutually offsetting effects.
low noise
AA thick
thick slice
slice better contrast resolution
means:
means: poorer edge definition
partial volume artifacts

high noise
AA thin
thin slice
slice poorer contrast resolution
means:
means: better edge definition
no partial volume artifacts
Source: CTC/CTM
© Siemens AG, 1998
Medical Engineering Group, Computed Tomography
CT Basics 34
Slice Thickness...
slice thickness 1/2 no. of x-ray quanta 50% noise level 1.4

Noise Image definition = spatial resolution

High
High

Low Low
1 2 3 5 10 mm 1 2 3 5 10 mm
Slice thickness Slice thickness

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 35
Slice Thickness...
3 mm Slice 10 mm Slice

Thicker slices give less noise & better


contrast detectability for soft tissue
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Medical Engineering Group, Computed Tomography
CT Basics 36
Slice Thickness
5 mm Slice 1 mm Slice

Thinner slices give better spatial resolution


for bony structures.
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Medical Engineering Group, Computed Tomography
CT Basics 37
Patient Size...
Noise

400%
Rule
Ruleofofthumb:
thumb:
300% The
Thenoise
noiselevel
leveldoubles
doublesfor
forevery
every88cm
cm
increase
increaseininpatient
patientdiameter.
diameter.
200%

100%

30 34 38 42 46 cm
Patient diameter
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 38
Patient Size...
An attenuation by a factor of 2 results from
each 4 cm increase in patient thickness, thus
increasing the pixel noise.
45 cm 28.8 cm

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 39
Image Display - Windowing
3000
Blood Liver
60 Tumor
Spleen Kidneys Heart
Bone Pancreas Bladder
40 Adrenal
Intestine
Gland

Water
0

Rule
Ruleofofthumb:
thumb:
-100
Mamma The
TheCT CTvalue
valueof
ofwater
waterisis00and
and
air
air-1000.
-1000.The
Therelative
relativevalues
valuesofof
-200
Fat
the
theother
othertissues
tissuesare
arecalculated
calculated
-900 Air Lung relative
relativeto
tothat
thatof
ofwater
water
-1000

This is the so-called CT number in Hounsfield unit (HU)


Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 40
Image Display - Windowing
The range of CT density values is defined from -1000 to
+3000, but the human eye can distinguish only 30 - 40 gray
scales at best.
Lung Window Mediastinum Window

So, the window settings must be in accordance


with the structures to be visualized
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Medical Engineering Group, Computed Tomography
CT Basics 41
Image Display - Windowing
Hounsfield
Gray scale
unit
+3000 display
White

Window Window
width W center C

0
Black

-1000 CT Windowing
Window width (W): the density range represented within the gray scale.

Window center (C): the center of the density range.


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Medical Engineering Group, Computed Tomography
CT Basics 42
Image Display - Windowing
Narrow Window Width Broad Window Width

Narrow window width: Broad window width:


High-contrast image, but Minor density differences
structures outside that window
appear homogeneous and
range may be inadequately
may be masked.
represented or overlooked.
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Medical Engineering Group, Computed Tomography
CT Basics 43
Double Window Technique
Hounsfield
Gray scale
unit
+3000 display
White

Window 1

0
Black
Window 2
-1000 CT Windowing
This is used for the display of two tissue types
differing greatly in their density values, such as
the lung & the mediastinum.
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 44
Double Window Technique*

To see both
lungs and
mediastinum
within image
simutanously

*Double window is not recommended for diagnosis.


Source: CTC/CTM
© Siemens AG, 1998
Medical Engineering Group, Computed Tomography
CT Basics 45
Image Display - Windowing

Double Window Lung Window Mediastinum Window

Image 1: Image 2: Image 3:


Both lung, Only lung Only thorax wall
thorax wall & visible & mediastinum
mediastinum visible
visible
Source: CTC/CTM
© Siemens AG, 1998
Medical Engineering Group, Computed Tomography
CT Basics 46
Extended CT Scale
Normally, CT values can be measured from -1024 to +3071,
but with SOMATOM Plus 4, this can be extended from -10240
to +30710 to visualize metals of high attenuation. Therefore,
it is always possible to measure the real CT value no matter
where and how the window is positioned.

Post operative femoral


head replacement - the
CT value is 6000 HU

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 47
Review vs. Magnification
Reviewed Magnified

Review: Magnification:
A zoom reconstruction from a purely optical
raw data to enhance magnification of image
sharpness of details data which may result in
blurred appearance
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 48
Image Artifacts - Origins

Image Artifacts
...
Operator
Motion error

Metal Technical
defects

Partial volume Beam hardening

Source: CTC/CTM
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CT Basics 49
Image Artifacts - Appearance

Image artifacts

Streak Cupping

Dark bar Ring

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Medical Engineering Group, Computed Tomography
CT Basics 50
Motion Artifact & Scan Time
Motion artifacts
Severe

Rule
Ruleof ofthumb:
thumb:
The
Theshorter
shorterthe
thescan
scantime,
time,the
the
less
lesslikely
likelymotion
motionartifacts
artifactsare
are
occur.
occur.
Moderate
Scan time (s)
Short Long

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 51
Motion Artifact & Correction
Motion artifacts can be compensated for by
the Motion Correction Algorithm (MCA)

w/o correction w/ correction


Source: CTC/CTM
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CT Basics 52
Metal Artifact

Metals, such as gold, absorb


x-radiation almost completely,
thus producing
“radiation shadows”,
leading to pronounced streak
artifacts over the entire
reconstructed image

This can only be avoided via a gantry tilt that excludes


the disturbing metallic objects from the slice plane.
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 53
Partial Volume Effect
Streak-like artifacts, also called partial volume artifact,
occur most frequently in the bony structures
at the base of the skull and the petrous bone region.

5 mm
That is because the
very dense structures
(bones) are only
partially included in the
slice, resulting in high
contrast errors.

Source: CTC/CTM
© Siemens AG, 1998
Medical Engineering Group, Computed Tomography
CT Basics 54
Partial Volume Effect
5 mm 2 mm

Selecting a thinner slice prevents such artifacts from


occurring, since high contrast structures are less
frequently partially included, but this inherently
increases the noise level, thus degrading contrast
resolution.
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 55
VAR - Volume Artifact Reduction
5 mm 2 x 2 mm

Combines several thin slices (which reduces the partial


volume artifact) to provide a thicker slice (which reduces
the pixel noise and offers good soft tissue discrimination).

Source: CTC/CTM
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CT Basics 56
Beam Hardening Effect
The x-ray photons emitted from the x-ray tube do
not all have the same energy. As they penetrate
the irradiated object, the spectrum is shifted to
higher energies - called “beam hardening”. In the
image, streak artifacts or the so-called “cupping
effect” can be seen.

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Medical Engineering Group, Computed Tomography
CT Basics 57
Beam Hardening & Correction

w/o correction w/ correction

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CT Basics 58
Beam Hardening & Correction
The “cupping” effect can be compensated for
by means of “beam hardening correction”
w/o correction w/ correction

severe cupping homogenuous CT values


Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 59
Technical Defects
The individual detector elements of a detector
system may not produce the same signal for the
same irradiation.

When a detector element


outputs an erroneous signal,
ring artifacts appear.

This can be eliminated by


calibration, if not, call
technical service!

Source: CTC/CTM
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CT Basics 60
Adaptive Filter
For a non-circular object, x-ray attenuation is
greater along the long axis than along the short
axis, therefore directional noise is seen.
w/o A.F. w/ A.F.

Source: CTC/CTM
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CT Basics 61
Artifacts & Corrections
The reasons for artifacts are quite diverse. What
we do is to perform corresponding corrections in
order to avoid them. But sometimes artifacts can
not be compensated for completely.

Nothing is perfect...

But we keep on working to reduce


them as much as possible!
Source: CTC/CTM
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CT Basics 62
For the Clinical Routine...
Since the influence on HC resolution & LC
resolution by changing parameters can be
contradictory, it is necessary to differentiate
between:

¨ A Soft tissue study (contrast detectability)


( >90% of routine studies, normally)

¨ A Bone study (spatial resolution)


(<10% of routine studies, normally)

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Medical Engineering Group, Computed Tomography
CT Basics 63
Clinical Requirements...

CT is really great!

But there are still some problems...

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Medical Engineering Group, Computed Tomography
CT Basics 64
Conventional CT...

Standard Scan:
- Longer cycle time I.S.D* I.S.D
- but instant display

* Inter Scan Delay

Dynamic Scan:
- Fast acquisition
- but delayed display

I.S.D I.S.D I.S.D I.S.D


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Medical Engineering Group, Computed Tomography
CT Basics 65
Problems of Conventional CT...
Misregistration due to different levels of respiration

Deep inspiration Moderate inspiration


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CT Basics 66
Breathing Was the Problem...

Sorry, my dear patient, the


lesion was missed because
you did not keep the same
inspiration level for each
scan...

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 67
Problems of Conventional CT...
Partial Volume Effect and slice location cause
misregistration and/or misdiagnosis

Best
case

Worst
case

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CT Basics 68
Location Was the Problem...

Sorry, the lesion was


missed because its location
did not fit my slice
position...

One mouse...

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Medical Engineering Group, Computed Tomography
CT Basics 69
Problems of Conventional CT...
l Scan influenced by respiration
l Image can’t be reconstructed anywhere as desired

Deep inspiration Moderate inspiration


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Medical Engineering Group, Computed Tomography
CT Basics 70
How can we improve this?

l Scan influenced by respiration


Make it as fast as possible within one
breathhold

l Image can’t be reconstructed anywhere as desired

Change "slice" into "volume"

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 71
Conventional vs. Spiral CT ...
2D Slice 3D Volume

w/ I.S.D w/o I.S.D

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 72
The 4 “C”s?
Continuously rotating tube/detector system

Continuous radiation

Continuous data acquisition

Continuous table feed

Spiral CT = Volume scan

Source: CTC/CTM
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CT Basics 73
Spiral CT...
“You said that images will contain artifacts if there
is any motion during the scan, but a spiral scan is
performed during constant table movement!”

Yes, therefore we need special techniques for


image reconstruction:

Spiral Algorithms
WIDE, SLIM & SLIM 2

Source: CTC/CTM
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CT Basics 74
Wide (360°) Algorithm
2 x 360° (2 full rotations) data acquisition is used
for 1 image reconstruction. Both are measured data.

measured
data

table position
slice
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CT Basics 75
Slim/Slim 2 (180°) Algorithm
2 x 180° (2 half rotations) data acquisitions are
used for 1 image reconstruction. Measured data
are weighted for Slim, and interpolated for Slim 2.

measured
data

complementary
data

table position
slice
Source: CTC/CTM
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CT Basics 76
Different Interpolations?

♣ The in-plane resolution for a homogenous


object in Z-direction is the same for WIDE,
SLIM & SLIM 2

♣ SLIM & SLIM 2 give better Z-direction


resolution than WIDE when pitch 0.5.

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 77
Effective Slice Thickness (FWHM*)
Slice Thickness (relative) 3.5
3
2.5
WIDE
2
1.5 SLIM
1
0.5
0
0 0.5 1 1.5 2 2.5 3
Pitch
WIDE makes FWHM wider, while SLIM/SLIM 2 keep
FWHM narrow.
* Full Width Half Maximum
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 78
Noise Amplitudes
Compared with Sequence scans, WIDE gives less noise, and
SLIM/SLIM 2 give more. But for all of them, noise amplitude
does not depend on pitch.

1.2 SLIM / SLIM 2


Noise (relative)

1 SEQ.
0.8 WIDE
0.6
0.4
0.2
0
0 0.5 1 1.5 2 2.5 3
Pitch

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 79
Noise Amplitudes

WIDE SLIM SLIM 2


Image reconstructed with WIDE algorithm shows less noise
than those with SLIM & SLIM 2, but for SLIM & SLIM 2
they are about the same.

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 80
Which Algorithm to Choose?
Slim: use it with HighRes algorithm when only
spatial resolution is most important (e.g. bone and
lung study)

Slim2: use it with algorithms from smooth to


standard when the contrast detectability is most
important (e.g. soft tissue study)

Wide: use it to achieve low noise only if z-direction


resolution is not important.

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 81
Spiral Parameters
Pitch:
Table feed per rotation divided by slice thickness

Table feed / rotation


Pitch =
Slice thickness

It is physically not possible to scan a volume


with gaps because x-rays always irradiate the
whole volume.
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 82
Spiral Parameters
Increment:
Determines degree of overlap between successive
images.
*slice = 10 mm

Increment = 3 mm
Increment = 5 mm
Increment = 10 mm

The smaller the increment, the more


the images are overlapped.
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 83
Advantages of Spiral CT...

u Scan a whole volume in one breath hold


u Reduce partial volume effects
u No gaps
u Overlapping images can be reconstructed
without additional dose
u High quality data for 3D-rendering

Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 84
Why Perform Spiral CT?
u Fast scanning of large anatomical volumes
u Gapless data acquisition during one breathhold
u Optimum utilization of contrast medium
u Retrospective reconstruction with arbitrary slice
increments

Conventional CT Scan Spiral CT Scan

Overlapping reconstruction gives


better z-axis resolution
Source: CTC/CTM
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Medical Engineering Group, Computed Tomography
CT Basics 85
When to Use Spiral CT?
u Use Spiral CT for contrast studies
u Use Spiral CT for all regions of the body
u Use it for pediatrics and trauma patients, who
require quick scanning
u Use it for long anatomical ranges

Always use Spiral if you intend to


perform 3D postprocessing (e.g. CTA) !

Source: CTC/CTM
© Siemens AG, 1998
Medical Engineering Group, Computed Tomography
CT Basics 86

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