Week 5 - Quiz 1

Question 1
The ancestor of modern corn is
maize
Bacillus thuringiensis
rice
teosinte

Question 2
True or false: A transgenic organism is an organism that has received a gene or genes from another
organism.
True
False

Question 3
How do scientists convince bacteria to synthesize transgenic genes?
By including a strong bacterial promoter on the recombinant plasmid
By inserting many genes into a bacteria
By using only bacterial proteins for transgenics
By choosing only bacteria which replicate quickly

Question 4
True or false: Restriction enzymes (restriction endonucleases) that are used to create recombinant
DNA cut the DNA in random locations.
True
False

Question 5

A tumor inducing (Ti) plasmid would likely have been used to create which of the following?
A transgenic mouse
Humulin
DNA ligase
A variety of corn expressing Bacillus thuringiensis toxin

Week 5 - Quiz 2
Question 1
Transgenic animals are:
Widely used as commercial products today
Less healthy than normal animals
Easier to create than transgenic plants or bacteria
Able to produce human proteins such as blood clotting factors

Question 2
True of false: Transgenic animals have genomes that have been permanently altered through
recombinant DNA technology.
True
False

Question 3
The most time consuming part of creating a transgenic animal is:
Creating a line of animals that are homozygous for the specific gene of interest
Maintaining a homozygous line
Picking a gene to insert into an animal
Finding a compatible gene to insert into the animal

Question 4

Gene therapy has been approved for:

Production of Human Growth Hormone
Lipoprotein lipase deficiency
Depression
Huntingtons Disease

Question 5
True or false: Gene therapy could not cure Nicholas Volker of his X-linked inhibitor-of-apoptosis
deficiency.
True
False

Week 5 - Quiz 3
Question 1
DNA fingerprinting CANNOT be used to do which of the following?
Study ancient fragments of DNA
Distinguish between identical twins
Identify murder victims
Find alleles for specific diseases like Huntingtons and cystic fibrosis

Question 2
True or false: Juries crave more forensic DNA evidence because criminals cannot fake DNA
evidence.
True
False

Question 3
Polymerase chain reaction (PCR):
Produces too little DNA for a full fingerprinting analysis

Clones small samples of DNA quickly

Clones all loci in a genome
Requires large samples of DNA

Question 4
True of false: DNA fingerprinting to determine paternity requires only the DNA fingerprints of the
potential fathers and the child.
True
False

Question 5
True of false: The high murder rate in Europe is due to 30% of Europeans having the warrior gene.
True
False

Week 5 - Quiz 4
Question 1
True of false: Cancer is the second major cause of death in the US.
True
False

Question 2
Cancer cells do NOT:
Work as a team player with your other cells
Divide excessively
Have an accumulation of DNA mutations
Have their own unique genome

Question 3

Telomerase contributes to what aspect of malignant tumors?

Immortality
Shorter telomeres
Movement around the body
Increased accumulation of mutations

Question 4
True or false: Mutations in proto-oncogenes are recessive mutations and mutations in tumor
suppressor genes are dominant mutations.
True
False

Question 5
BRCA1 and BRCA2 predispose women to what types of cancer?
All kinds of cancer
Breast cancer
Colon cancer
Skin cancer

Week 5 - Quiz 5
Question 1
All of the following are traditional treatments for cancer EXCEPT:
Surgery
Oncolytic viruses
Radiation
Chemotherapy

Question 2
Treatment of cancer using oncolytic viruses requires:

Mice
An injection only into the tumor
Transport by macrophages
An aggressive immune system to kill the virus

Question 3
True of false: The FDA has approved using gene therapy for the treatment of estrogen receptor
positive breast cancer.
True
False

Question 4
Ras is a __(1)__ and p53 is a __(2)__.
1- tumor suppressor gene, 2- proto-oncogene
1- proto-oncogene; 2- tumor suppressor gene
1- oncogene; 2- oncogene
1- proto-oncogene; 2- oncogene

Question 5
Which of the following decreases the rate of colon cancer:
A diet low in animal fat or red meat
Ultraviolet (UV) radiation
Smoking
Viral Infections

Week 5 - Summary Quiz

Question 1
True or false: Transfer of DNA across different species is called horizontal gene transfer.
True

False

Question 2
People with two versions of the delta 32 version of CCR5 are highly resistant to which disease?
Sickle cell anemia
HIV
Cancer
Cystic fibrosis

Question 3
True or false: People have successfully used their genes for certain diseases, such as Huntington's
disease, as part of their defense in court.
True
False

Question 4
Programmed cell death is called:
Apoptosis
Cancer
Telomerase
An oncolytic virus

Question 5
The single biggest cause of cancer that is preventable is:
Stress
Smoking
Sunshine
Poor diet