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  • Methylation Diagram

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    pkdo2003
    381 visualizações1 página
    This document outlines several metabolic cycles and pathways related to oxidative stress and inflammation, including the folate cycle, methionine cycle, urea cycle, arginine pathway, transsulfuration pathway, cobalamin cycle, and neurotransmitter pathways. Key molecules involved include methionine, homocysteine, cysteine, glutathione, dopamine, serotonin, nitric oxide, and ammonia. Imbalances or deficiencies in these cycles and pathways can lead to oxidative damage, microglial activation, and neuronal damage.

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    Methylation

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    This document outlines several metabolic cycles and pathways related to oxidative stress and inflammation, including the folate cycle, methionine cycle, urea cycle, arginine pathway, transsulfuration pathway, cobalamin cycle, and neurotransmitter pathways. Key molecules involved include methionine, homocysteine, cysteine, glutathione, dopamine, serotonin, nitric oxide, and ammonia. Imbalances or deficiencies in these cycles and pathways can lead to oxidative damage, microglial activation, and neuronal damage.

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    © All Rights Reserved
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    Sinalizar o conteúdo como inadequado
    381 visualizações1 página

    Methylation Diagram

    Enviado por

    pkdo2003
    This document outlines several metabolic cycles and pathways related to oxidative stress and inflammation, including the folate cycle, methionine cycle, urea cycle, arginine pathway, transsulfuration pathway, cobalamin cycle, and neurotransmitter pathways. Key molecules involved include methionine, homocysteine, cysteine, glutathione, dopamine, serotonin, nitric oxide, and ammonia. Imbalances or deficiencies in these cycles and pathways can lead to oxidative damage, microglial activation, and neuronal damage.

    Direitos autorais:

    © All Rights Reserved
    Baixe no formato PDF, TXT ou leia online no Scribd
    Sinalizar o conteúdo como inadequado
    de 1

    Methionine Cycle

    Folate Cycle
    Urea
    Arginine

    MAT

    Neurotransmitter

    THF

    Tryptophan

    Thymidine
    synthesis

    Tyrosine
    BH4

    dUMP

    Methionine

    DMG
    BHMT
    MS

    ammonia

    Microglial
    Activation

    Dopamine
    MAO B

    HIAA

    COMT

    Homocysteine
    B6,
    CBS
    P5P
    Cystathionine

    HVA
    Peroxynitrate
    Super Oxide

    Oxidative-Inflammatory Disease

    Creatine
    Creatinine
    adenosine

    Transsulfuration

    Ammonia
    Cysteine + KG
    MAO B
    Taurine

    0 BH4

    Neuronal
    Damage

    Serotonin
    MAO A

    Cobalamin
    Cycle

    NorEp
    1 BH4

    Citrulline + NO

    SAHH
    5 Methyl
    THF

    BH2
    2 BH4

    Urea

    SAH

    MTHFR
    MSR

    NOS

    Methylation
    Guanido Ac

    TMG

    Ornithine
    DHPR

    SAMe

    DNA, RNA,
    Protein,
    Lipids

    COMT

    Sulfite
    Moly

    Glutathione
    SUOX

    Sulfate
    VMA

    Adapted from
    Dr. Amy Yasko
    2012 The Institute for Functional Medicine

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