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INTRODUCTION TO

PHARMACOLOGY AND
THERAPY
Dwi Indria Anggraini

Dept. of Pharmacology and Therapy


Faculty of Medicine Lampung University

Definition
s

Pharmacogenet
ic

Pharmacotherapeuti
Pharmacolog
c
y
Pharmacoeconomic
Pharmacokinetic

Pharmacodynami
Clinical
c
Pharmacolog
Pharmacy
y

Pharmacogno
sy

Pharmacolo
gy
The knowledge of :

Pharmacokinetics

Pharmacy :
The scientific study about preparing,
compounding and dispensing of drugs

Pharmacognosy :
The branch of pharmacology that study
about sources of drugs.

Clinical Pharmacology:
The scientific study of drugs in man

Pharmacotherpeutics
The study of the drugs use in the
prevention & treatment of disease
Some mechanism of actions of drugs :
Stimulate / depress biochemical or
physiological functions relief of symptoms
Alter the course of disease
Eliminate the pathogenic cells / organisms

Pharmacogenet
ics

Study relationship of genetics factors to


variations
in drug response (Brody, 1998)
Concerned with drugs responses that are
governed
by heredity (Laurence & Bennet,
1987)

Inherited causal factors are :


Biochemical genes govern the production
enzymes
Anatomical mydriatics induced glaucoma in
patients with a shallow anterior eye chamber

Toxicology
Aspect of pharmacology that deals with AEs
of drugs
Concerned with
- drugs used in therapy
- chemical household and industrial
intoxication

So what is
drug?

Chemical agent that effect the living process


Any substance used to modify physiological
system OR pathological condition for the
benefit of the recipient

Drugs
Essential drugs
meet the health of the majority of
population
Generic drugs
marketed by any producers under nonproprietary (=INN) / branded names
exp: paracetamol

Patent drugs (branded drug)


pharmaceutical products marketed under
branded names

Drugs in the market:


classification

a. on-ethical drugs sold without R/

Unlimited drugs (B-class) = OTC drugs


Without cautionary labeling

Limited drugs (W-class) = semi OTC drugs


With cautionary labeling
Pharmacy/licenced drug store

b. Ethical drugs sold with R/

Potent drugs (G-class)


Narcotics drugs (O-class)

Thank You.....

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