Allergens

Allergen
(trigger)

Antigens identify the trigger

Antibodies bind with antigens

Antigen-Antibody Reaction

Mast Cells/Basophils

Itchiness, Redness

Histamine

Cell Fluid Shifting

Edema

Swelling

Inflammation

Skin, eyes, lips

Laryngeal
edema

DOB, stridor

Bradykinin/Leukotrienes

Vasodilatation

Maldistribution of blood

Capillary permeability

Venous Return

Blood flow

Cardiac Output

Glomerular Filtration

Tissue Perfusion

Urine Output

BP

Shock
Blood vessels

Oxygen

Loss of
consciousness

Binds with IgE