Escolar Documentos
Profissional Documentos
Cultura Documentos
:
:
C
........................................................................................................................................3
1. ............................................................................4
1.1. , , .................................4
1.2. ...........................................................................................4
2. .......................................................................5
2.1 .....................................................................................5
2.2 ...........................................................................5
3. ...................................................................6
4..................................................................................................................................7
5. ......................................................................8
6..............................................................................................................................8
6.1........................................................................................................................8
6.2. ...........................................................................................................9
7. - , .........................................11
7.1. .............................................................................11
7.2 ....................................................................12
1. .......................................12
8..............................................................................................................................13
...........................................................................................................14
10 15
..
.
.
.
: , ,
, , 3,
..
,
. 6-8%
( 8-10% 3 ).
3-4%.
, ,
.
,
,
,
.
1.
, .
, , .
.
1.1. , , 1
;
.
.
.
1.2.
,
,
, ( ).
( )
.
, , .
,, , , , ,
.
, , , .
( )
.
.
IgE.
.
1 Vandenplas Y, Koletzko S, Isolauri E, Hill D, Oranje AP, Brueton M, Staiano A,
Dupont C.Guidelines for the diagnosis and management of cow's milk protein
allergy in infants. Arch Dis
Child 2007 Oct;92(10):902-8
2.
.
,
. .
2.1
( ),
( ).
.
, .
.
2.2
, , ,
.
.
10
( ).
(, ).
, .
2.3
, , .
o
.
IgE
1-2 ,
.
.
.2
3.
. .
( )
- :
o ( 1-2 ).
o ,
.
o
.
().
o
( ) .
o 1 2
( ),
. 5
.
.
,
.
:
.
Ig
. IgA IgG
.
IgE .
-
.
e .
4.
. ;
.
.
(, ),
.
.
.
- .
5.
.
2 , 75% 3 .
6.
,
. ,
.
,
, . ,
,
.
IgA
.
6.1.
, , ,
.
.
. .
,
(, ),
() .
B12 .
., ,
,
() .
(,
, ),
.
,
.
.
6.2.
1 100
. 1:222 .
60 75% ;
.
10-
; . ,
.
Dermatitis herpetiformis 1 4 .
6.3.
:
IgA
80 95%
. 95%.
IgA
IgA .
, ( )
.
. , (Crosby
Watson ) .
.
.
,
.
.
- (2,3).
6.4.
,
, ` .
, .
.
, .
,
, , . ,
.
3 dapson.
.
1 2 . ,
dapson- 1-2 .
.
, .
3 ,
.
10
41/20094
.
.
20 mg/kg .
20-100 mg/kg
7. - ,
. ,
,
.
.
7.1.
: , , ,
, , ,
,
,
: , ,
,
(,,),
, IgG
.
.
4 Collin P, Huhtala H, Virta L, Kekkonen L, Reunala T. Diagnosis of celiac disease in
clinicalpractice: physician's alertness to the condition essential. J Clin
Gastroenterol 2007 Feb;41(2):1526. PubMed
11
7.2
()
-IgG
( )
( )
1.
(IgE)
1-2
.
( )
(IgG)
,
()
12
8.
.
.
. 5%
4% .
, .
. ,
, , , , ,
, , , .
,
.
.
,
,
.
.
.
13
1. Lack G. Clinical practice. Food allergy. N Engl J Med 2008 Sep
18;359(12):1252-60. PubMed
2. Burks AW. Peanut allergy. Lancet 2008 May 3;371(9623):1538-46. PubMed
3. McFarlane XA, Bhalla AK, Reeves DE, Morgan LM, Robertson DA.
Osteoporosis in treated adult coeliac disease. Gut 1995 May;36(5):710-4.
PubMed
4. Corazza GR, Di Sario A, Cecchetti L, Tarozzi C, Corrao G, Bernardi M,
Gasbarrini G. Bone mass and metabolism in patients with celiac disease.
Gastroenterology 1995 Jul;109(1):122-8. PubMed
5. http://doktori.mk/element/view/4e8a2a07edc54/alergija-na-hrana
6. http://zdravstvo.gov.mk/-
7. http://www.food.gov.uk/business-industry/allergy-guide -
8. http://www.nice.org.uk/guidance/cg116-
9. http://www.aafa.org/display.cfm?id=9&sub=20&cont=723
14