Faculty of Pharmaceutical Sciences

Chulalongkorn University

FACULTY OF PHARMACEUTICAL SCIENCES

CHULALONGKORN UNIVERSITY
Department | Members | Research and Publication
Members:
Garnpimol C. Ritthidej
(Prof. Dr.)
Waraporn Suwakul
(Assoc. Prof. Dr.)
Parkpoom Tengamnuay
(Assoc. Prof. Dr.)
Pornpen Werawatganone
(Assoc. Prof. Dr.)
Nontima Vardhanabhuti
(Assist. Prof. Dr.)
Walaisiri Muangsiri
(Assist. Prof. Dr.)
Angkana Tantituvanont
(Assist. Prof. Dr.)
Vipaporn Panapisal
(Assist. Prof. Dr.)
Phanphen Wattana-Arsakit
(Dr.)
Narueporn Sutanthavibul
(Dr.)
Jittima Chatchawalsaisin
(Dr.)
Dusadee Charnvanich
(Dr.)
Prapasri Sinswat
(Dr.)
Anyarporn Tansirikongkol
(Dr.)
Jutarat Kitsongsermthon
(Dr.)
Wanchai Chongcharoen
(Dr.)
Phatsawee Jansook
(Dr.)
Weerakiat Boonkanokwong

Department of Pharmaceutics
and Industrial Pharmacy
T h e D e p a r t m e n t o f P h a r m a ce u t i c s a n d
Industrial Pharmacy is an academic unit with an
unwavering commitment to excellence in research,
education and service. The department is a part of the
Faculty of Pharmaceutical Sciences with 18 faculty
members who have advanced knowledge and expertise
in the fields of pharmaceutical technology and
pharmaceutics.
The departments areas of specialization reflect a
m u l t i d i s c i p l i n a r y s c i e n ce t h a t co n ce r n s t h e
development, production and characterization of
dosage form as well as the action and disposition of
drug in the body. Briefly, it is the study of the
relationships between drug formulation, delivery,
disposition and therapeutic response. Another aspect
of specialization deals with various pharmaceutical
te c h n o l o g y a n d r e g u l a to r y i s s u e s i n v o l v i n g
pharmaceutical/nutraceutical/cosmeceutical
production in the industry.

Department of Pharmaceutics and Industrial Pharmacy

Faculty of Pharmaceutical Sciences

Major Research Areas

Pharmaceutical/ biopharmaceutical processing technology
research utilizing process
analytical technology (PAT) and
process simulation software
Conventional and novel drug
delivery systems development
Adjuvants and vaccine delivery
development
Cosmeceutical and
nutraceutical product
development
Functionalized pharmaceutical
materials
Bioavailability and
bioequivalence studies
Development of products and
excipients based on natural
resources for pharmaceutical,
nutraceutical and cosmeceutical
uses
Pharmacokinetic research
Solid state chemistry evaluation
Pharmaceutic and drug delivery
Pharmaceutical engineering
Chemical kinetics

Chulalongkorn University
The faculty members of the department focus
on the development of novel delivery systems to
optimize drug absorption or site-specific delivery of
bioactive compounds which are unable to be
eectively delivered by conventional dosage forms.
Such novel systems include micro-/nano-particulate
carriers, liposomes, dr ug -polymer conjugates,
functionalized membranes and films as well as various
viral and non-viral vectors. These systems are utilized
t o f a c i l i t a t e m e m b r a n e u p t a ke o f d r u g s ,
m a c r o m o l e c u l e s , a n d g e n e t i c m a te r i a l s . T h e
development of advanced vaccine deliver y and
adjuvants are also emphasized.
Apart from the research in drug deliver y
systems, increasing interest has been placed on the
utilization of natural resources in Thailand for
pharmaceutical, nutraceutical, and cosmeceutical
b e n e f i t s . Ma n y n a t u r a l s u b s t a n ce s i n c l u d i n g
biopolymers form plant and animal resources have a
great potential for development into safe, eective,
and commercially viable products for local and
international markets. Research in this area is
expected to add the value to the countrys rich natural
resources and help to reduce the import of raw
materials, resulting in the stimulation of local
e co n o m y. T h e a r e a s o f s p e c i a l i z a t i o n i n t h e
department may be integrated with industrial
expertise through research collaboration with the Thai
pharmaceutical/natraceutical and cosmeceutical
manufacturers resulting in projects with high
industrial potential or technologies that can solve
industry-based limitations. Through close aliation
with Chulalongkorn University Drug and Health
Products Innovation Promotion Center (CU.D.HIP),
an up-to-date technologies and knowledge will be
eectively transferred to the Thai industry for self
reliance and the sustainable growth of Thailands own
economy.

Physical pharmacy

Department of Pharmaceutics and Industrial Pharmacy

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Publication
Jain R, Monthakantirat O, Tengamnuay P and De-Eknamkul W (2014) Avicequinone C isolated from Avicennia marina exhibits 5 reductaseType 1 inhibitory activity using an androgenic alopecia relevant cell-based assay system. Molecules 19:6809-6821.
Temeeyasen G, Srijangwad A, Tripipat T, Tipsombatboon P, Piriyapongsa J, Phoolcharoen W, Chuanasa T, Tantituvanont A and Nilubol D
(2014) Genetic diversity of ORF3 and spike genes of porcine epidemic diarrhea virus in Thailand. Infection, Genetics and Evolution
21:205-213.
Pichayakorn W, Suksaeree J, Boonme P, Amnuaikit T, Taweepreda W and Ritthidej GC (2013) Deproteinized natural rubber film forming
polymeric solutions for nicotine transdermal delivery. Pharmaceutical Development and Technology 18:1111-1121.
Pichayakorn W, Suksaeree J, Boonme P, Taweepreda W, Amnuaikit T and Ritthidej GC (2013) Deproteinised natural rubber used as a
controlling layer membrane in reservoir-type nicotine transdermal patches. Chemical Engineering Research and Design 91:520-529.
Sinsuebpol C, Chatchawalsaisin J and Kulvanich P (2013) Preparation and in vivo absorption evaluation of spray dried powders containing
salmon calcitonin loaded chitosan nanoparticles for pulmonary delivery. Drug design, development and therapy 7:861-873.
Sukhaphirom N, Vardhanabhuti N, Chirdchupunseree H, Pramyothin P and Jianmongkol S (2013) Phyllanthin and hypophyllanthin inhibit
function of P-gp but not MRP2 in Caco-2 cells. Journal of Pharmacy and Pharmacology 65:292-299.
Wongwanakul R, Vardhanabhuti N, Siripong P and Jianmongkol S (2013) Eects of rhinacanthin-C on function and expression of drug eux
transporters in Caco-2 cells. Fitoterapia 89:80-85.
Chuenkitiyanon S, Vardhanabhuti N and Jianmongkol S (2012) A potential benefit of quercetin in preserving tight junction integrity. Journal
of Epithelial Biology and Pharmacology 5:28-31.
Panapisal V, Charoensri S and Tantituvanont A (2012) Formulation of microemulsion systems for dermal delivery of silymarin. AAPS
PharmSciTech 13:389-399.
Pichayakorn W, Suksaeree J, Boonme P, Amnuaikit T, Taweepreda W and Ritthidej GC (2012) Nicotine transdermal patches using polymeric
natural rubber as the matrix controlling system: Eect of polymer and plasticizer blends. Journal of Membrane Science 411-412:81-90.
Pichayakorn W, Suksaeree J, Boonme P, Amnuaikit T, Taweepreda W and Ritthidej GC (2012) Deproteinized natural rubber latex/
hydroxypropylmethyl cellulose blending polymers for nicotine matrix films. Industrial and Engineering Chemistry Research 51:8442-8452.
Pichayakorn W, Suksaeree J, Boonme P, Taweepreda W and Ritthidej GC (2012) Preparation of deproteinized natural rubber latex and
properties of films formed by itself and several adhesive polymer blends. Industrial and Engineering Chemistry Research 51:13393-13404.
Sasivimolphan P, Lipipun V, Ritthidej G, Chitphet K, Yoshida Y, Daikoku T, Sritularak B, Likhitwitayawuid K, Pramyothin P, Hattori M and
Shiraki K (2012) Microemulsion-based oxyresveratrol for topical treatment of herpes simplex virus (HSV) infection: Physicochemical
properties and ecacy in cutaneous HSV-1 infection in mice. AAPS PharmSciTech 13:1266-1275.
Suksaeree J, Boonme P, Taweepreda W, Ritthidej GC and Pichayakorn W (2012) Characterization, in vitro release and permeation studies of
nicotine transdermal patches prepared from deproteinized natural rubber latex blends. Chemical Engineering Research and Design
90:906-914.
Bhattachar SN, Risley DS, Werawatganone P and Aburub A (2011) Weak bases and formation of a less soluble lauryl sulfate salt/complex in
sodium lauryl sulfate (SLS) containing media. International Journal of Pharmaceutics 412:95-98.
Lipipun V, Sasivimolphan P, Yoshida Y, Daikoku T, Sritularak B, Ritthidej G, Likhitwitayawuid K, Pramyothin P, Hattori M and Shiraki K
(2011) Topical cream-based oxyresveratrol in the treatment of cutaneous HSV-1 infection in mice. Antiviral Research 91:154-160.
Rungphanichkul N, Nimmannit U, Muangsiri W and Rojsitthisak P (2011) Preparation of curcuminoid niosomes for enhancement of skin
permeation. Pharmazie 66:570-575.
Charnvanich D, Vardhanabhuti N and Kulvanich P (2010) Eect of cholesterol on the properties of spray-dried lysozyme-loaded liposomal
powders. AAPS PharmSciTech 11:832-842.
Jansook P, Ritthidej GC, Ueda H, Stefnsson E and Loftsson T (2010) CD/HPCD mixtures as solubilizer: Solid-state characterization and
sample dexamethasone eye drop suspension. Journal of Pharmacy and Pharmaceutical Sciences 13:336-350.

Department of Pharmaceutics and Industrial Pharmacy

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Ketmaro P, Muangsiri W and Werawatganone P (2010) UV spectroscopic characterization and stabilities of natural colorants from roselle
calyx, lac resin and gardenia fruit. Journal of Health Research 24:7-13.
Sritularak B, Tantituvanont A, Chanvorachote P, Meksawan K, Miyamoto T, Kohno Y and Likhitwitayawuid K (2010) Flavonoids with free
radical scavenging activity and nitric oxide inhibitory eect from the stem bark of Artocarpus gomezianus. Journal of Medicinal Plants
Research 4:387-392.
Wurster DE and Werawatganone P (2010) Influence of the polymer-micelle interaction on micelle-substrate binding. Journal of
Pharmaceutical Sciences 99:1440-1451.
Chanvorachote B, Nimmannit U, Muangsiri W and Kirsch L (2009) An evaluation of a fluorometric method for determining binding
parameters of drug-carrier complexes using mathematical models based on total drug concentration. Journal of Fluorescence 19:747-753.
Jakmatakul R, Suttisri R and Tengamnuay P (2009) Evaluation of antityrosinase and antioxidant activities of Raphanus sativus root:
Comparison between freeze-dried juice and methanolic extract. Thai Journal of Pharmaceutical Sciences 33:22-30.
Kusonwiriyawong C, Pichayakorn W, Lipipun V and Ritthidej GC (2009) Retained integrity of protein encapsulated in spray-dried chitosan
microparticles. Journal of Microencapsulation 26:111-121.
Tantituvanont A, Yimprasert W, Werawatganone P and Nilubol D (2009) Pharmacokinetics of ceftiofur hydrochloride in pigs infected with
porcine reproductive and respiratory syndrome virus. Journal of Antimicrobial Chemotherapy 63:369-373.
Werawatganone P and Muangsiri W (2009) Interactions between charged dye indicators and micelles to determine the critical micelle
concentration. Asian Journal of Pharmaceutical Sciences 4:221-227.

Department of Pharmaceutics and Industrial Pharmacy