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million Americans with Alzheimers were probably not told they have it by a
physician.
The latest advance in Alzheimer's diagnosis came this year, when the
U.S. Food and Drug Administration gave its approval to a radioactive dye that
can be used to determine whether the protein of Alzheimer's disease is
accumulating in the brain, says Dr. Jeffrey Cummings, a neurologist and
researcher and director of the Cleveland Clinic Lou Ruvo Center for Brain
Health. (reviewjournal.com) The radioactive dye binds to amyloid plaque that
accumulates in the brain of a person with Alzheimer's. Then, a PET scan is
conducted, and the presence, or absence, of the plaque is revealed.
(reviewjournal.com) With these new tests, clinical trials can begin using a
person who is not showing symptoms in their daily lives yet, but their brain
scans show that there are already abnormalities presenting; this would allow
access to very early stages of the disease, and new research and
information. If no amyloid plaque is found, that can rule out Alzheimers,
which will allow further testing for a different dementia-related disease. This
is important because with other certain types of dementia, Alzheimers
medications actually worsen the conditions. "So it's the interaction between
what the scan tells us and the clinical examination. That's why the doctor is
still important here," Cummings continues. "And that, of course, is why we
have to teach the medical community how to use this scan, because you
could easily get a positive scan and say, 'You have Alzheimer's disease,' and
we don't think that. We think there's a lot of uncertainty in what's going to
Cleveland Clinic Lou Ruvo Center for Brain Health, are strongly
recommending patients who do not show any symptoms to not get screened,
because if they have no symptoms they cannot be treated for anything. "At
this point, we don't have any medicine we know of to take in advance to
prevent the disease, I would not recommend getting a test just to know."
(reviewjournal.com) Getting a test just for curiositys sake could be
extremely expensive. For some people, however, who know they have a
family history of the disease, knowing ahead of time could be very beneficial
in the long run. For example, knowing it might be a part of your future would
allow you to be prepared to seek treatments as soon as you do recognize
that you are showing symptoms, as well as have a plan in place for at home
care, or clinical care for when the time comes. On the negative side,
however, getting screened ahead of time and being labeled as someone who
might possibly develop the disease could be detrimental to a career or other
opportunities. For example, an employer might be less willing to hire
someone and provide them with insurance benefits if they know he or she is
more likely to develop a life threatening disease within the next ten years or
so. Other complications have also come about; such as the fact that the test
costs about $4,400, which would not be covered by medical insurance or
Medicare.
According to the article A Review of the Evidence for and against
Screening for Alzheimer Disease in Primary Care, there are three keys to
successful treatments: early detection, the use of currently approved
was no way of knowing the patient had the disease in the first place.
Although it may be a costly expenditure, I think in the long run it would
greatly benefit Alzheimers research. If we can somehow find the means to
make early detection screening a common practice in primary care, it would
give researchers the grounds they need to perform experiments on patients
whose minds are not already completely degenerated; which could do
wonders for the research.
Overall, I think both sides of the argument have valid points. However,
I think early detection screening will be a key factor in making more progress
in the research for Alzheimers. "A big problem in Alzheimer's disease and
research is that we're not catching people early enough, Cummings says,
"There are hundreds of thousands of people out there that have symptoms.
(reviewjournal.com) This is clearly a prevailing problem in the United States,
and the statistics show that it will only continue to get worse in the years to
come.
Works Cited
"2015 Alzheimers Disease Facts and Figures." Alz.org. Web. 2 Nov. 2015.
<https://www.alz.org/facts/downloads/facts_figures_2015.pdf>.
"Alzheimer's & Dementia Testing Advances | Research Center | Alzheimer's
Association." Alzheimer's Association. Web. 9 Nov. 2015.
<http://www.alz.org/research/science/earlier_alzheimers_diagnosis.asp
>.
Ashford, J. Wesson, Soo Borson, and Ruth O'Hara. "Should Older Adults Be
Screened for Dementia?" Sciencedirect.com. Elsevier, 1 Apr. 2006.
Web. 24 Nov. 2015.
<http://www.sciencedirect.com/science/article/pii/S1552526006000458
>.
Brain Tangles - Alzheimer's Association." Alzheimer's Brain Tangles Alzheimer's Association. Web. 9 Nov. 2015.
<https://www.alz.org/braintour/tangles.asp>.
Solomon, Paul, and Cynthia Murphy. "Should We Screen for Alzheimer's
Disease? A Review of the Evidence for and against Screening for
Alzheimer's Disease in Primary Care Practice." Wncln.org. Web. 18 Nov.
2015. <http://0eds.a.ebscohost.com.wncln.wncln.org/eds/pdfviewer/pdfviewer?
sid=c88eb7d1-82c1-4074-89db2158eade8cd9@sessionmgr4005&vid=1&hid=4211>.
"TOUGH TESTS: Why Get Screened for Alzheimer's When There Is No Cure?"
Las Vegas Review-Journal. 12 Dec. 2012. Web. 2 Nov. 2015.
<http://www.reviewjournal.com/life/health/tough-tests-why-getscreened-alzheimers-when-there-no-cure>.