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Gas Exchange
Respiratory System:
Function
1.Primary function of the
respiratory system is to obtain
oxygen for use by body's cells
& eliminate carbon dioxide
that cells produce .
2.Respiratory System includes
the respiratory airways leading
into (& out of) lungs plus the
lungs themselves
Pharynx
Trachea (windpipe)
The Lungs
Bronchioles
The Alveoli
The average
adults lungs
contain about 600
million alveoli
The alveoli are
surrounded by
capillary networks
13
The Alveoli
Single layer of
cells provides easy
passage for gases
entering
surrounding
capillaries
(oxygen) and gases
leaving the
capillaries (carbon
dioxide).
14
Norma
Collapse
l
d
Membrane that
surrounds each lobe of
the lungs. Separates the
lungs from the chest wall
and is filled with fluids
that reduce the friction
between the lungs and
the chest cavity during
inhalation.
A hole in the pleural
cavity is called
pneumothorax
(collapsed lung), and will
make it impossible for the
chest cavity to establish
pressure differences.
17
18
Respiratory Volume
Respiratory Volume
Lung volume
21
The Respiratory
System
Mechanics of Breathing
22
Pressure
The Diaphragm
A band of muscles
that separates the
chest cavity from
the digestive cavity
24
The Diaphragm
Contraction
When the diaphragm
contracts it flattens
pulling downwards.
This increases the
volume of the lungs,
decreasing plural
pressure.
This allows air to
enter the lungs
(atmospheric
pressure is higher)
Relaxation
Diaphragm returns to
dome shape due to the
force exerted by the
organs in the abdomen
Chest volume decreases
causing pleural
pressure to increase
Pleural pressure is
greater than
atmospheric pressure
causing air to leave the
lungs
25
The Diaphragm
26
27
External Intercostal
muscles
Internal Intercostal
Muscles
29
Mechanics of Breathing
30
The Respiratory
System
Regulation
31
Regulation of
Respiration
Regulation
depends
primarily on the
respiratory
control centers
located in the
medulla and
pons of the
brain stem
32
Regulation of
Respiration
Chemoreceptors
Primary Regulatory
System
Carbon Dioxide chemoreceptors
in the medulla oblongata are the
primary regulatory system
When CO2 levels are detected to
be too high, and acceleration of
breathing rate is triggered
35
Secondary Regulatory
System
Secondary Regulatory
System
38
Oxygen Transport
Not enough oxygen can diffuse into the
blood plasma for cellular use (0.3mL per
100mL of blood). The body needs much
more.
Oxygen is carried in blood:
1 - bound to hemoglobin (98.5% of all
oxygen in the blood or 20mL per 100mL of
blood)
Oxygen + Hemoglobin = Oxyhemoglobin
2 - dissolved in the plasma (1.5%)
40
Oxygen Transport
Carbon Dioxide
Transport
Carbon Dioxide
Transport
when CO2 (released by cells making ATP)
combines with H2O carbonic acid is formed
If too much carbonic acid was formed in the
blood, pH would drop to dangerous levels.
due to the enzyme in red blood cells called
carbonic anhydrase, Carbonic acid further
dissociates into bicarbonate and hydrogen
ions.
43
Carbon Dioxide
Transport
Diseases and
disorders of the
respiratory tract
45
Hiccups
Laryngitis
47
Bronchitis
Bacterial, viral,
environmental
-Is an inflammation of
the bronchi, causing
them to over-secrete
mucus, which in turn,
causes coughing.
-Especially bad in the
bronchioles where
there is no cartilage
48
Pneumonia
-Pneumonia is an inflammation or
infection of the lungs.
-The lungs' air sacs fill with pus,
mucus, and other liquid and can not
function properly. Oxygen can not
reach the blood.
Normal
49
Pleurisy
Asthma
Emphysema
Lung cancer