Hiba Ali

U00041776

Assignment

Monday 2-5

Dispense 100ml of calamine lotion BP

Rx
Calamine

15gm

Zinc Oxide

5gm

Bentonite

3gm

Sodium Citrate

0.5gm

Liquefied Phenol (80% w/w) 0.5ml (density:1.055g/ml)

Glycerol

5ml

Water qs.

100ml

1. What can calamine be used for and where could you find out information
about it?
Calamine is used to relieve pain, itching, and discomfort from minor skin
irritations such as poison ivy, poison oak, and poison sumac. It also helps
to dry the oozing and weeping caused by irritation due to these plants.
And, you can find information about it in the BNF or APF.

2. Whats the dosage form of the previous preparation?

Lotion (topical)
3. How many phenol (w/w) is in 0.5ml liquefied phenol?
80% (w/w) = 80 g 100 g
100/1.05 density of phenol = 95.2 ml
80 g

95.2 ml

Xg

0.5 ml

x= 0.42g

4. Justify the use of each compound in the given formula?

Zinc oxide: active ingredient antiseptic

Bentonite: suspending agent
Sodium citrate: controls flocculation SAA, preservative
Glycerol: thickening agent, helps powder to adhere on the skin, emulsifying
agent
Phenol: preservative, co-solvent, antiseptic
Water: Solvent

5. What would be the most important auxiliary label for the formulation?

For external use only

Shake well before use
Don't apply to broken skin

6. Dispense and council?

Avoid Exposure to sunlight
Do not use/Throw away after 28 days