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rl

r.'ot:il ;Itrrlr

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i i)ft] t'ittltlncl e

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ilrmlhluiirir{u (l()
Sliititir il 'tr i rtiirtt:;
i( ' i t u i ir{;at(} :; islilir i c:l

l;llo :,i:;{crn lrr

)l

('ir1IiIIIrr'';

tt.q.:n i i lI

*'l'r'nlrsl:ol-lc

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( r)iir'tlr
rlr.:

lc

kr lrrir"ir.r;tr-:s

l{.ctir';lr"j;t el* lr"olrrc:l r cr;l.ccrl

5isr'ru1;r li

"t

.t'
,>

) sii;tllr;t c!lilulltlor ir} ii.il con}r, :..,i:,,tt_tl;l


rlc riutsllot'lrt

riIlr:,trie i lts 1rr.Irr

\" l;rs

rr

lii!eql:

5is[i'itil ciri:ul;rlrir o ;lllicir:ru;1tr. 'C5!)i rti-livci


l)cl() {l.il}Sl)1t tr'
r!,.: g,,11 llr.'rrl:;:; iittc sc tr..tiiillltj
lrr"t ;5i1i;0s in!.:t":\iil":itis
{".}l'l tli{) :;ill ctit.lllllttt crs i.t()l qrq
l)cri tirtrr )\ ]i )!-i:.t (:;
ll

.r":lnSlltrs q.lc ;l:llle irl;is. t.csrlrit;:,


r*rlcc*Iits llr: l.()cli:i r-: htrct.r-i;s ,iI*I
i

r.lt

cclirl;ls

i I tt"c5

l()r'tit:

ri:;

i.llil}. irluirlrl rccollliio r.ios

e sl_;.r)r5 ctr-i-, is
ilc,itin:i.
*'{}l}ttil iiillit'i; (1t ctillgtllltilo.;rli:rririlis
!lli}l(lrrls- lillitros r:
lilrirr:ilos eluc ir;o tr)art {) slngllL

CI {)s v[s(]s liiriticos dl-cnllll"l


{.i:j ltril.lliirr i.os trlrl.ris tti!iii:,,1i1

()t'llllisrrirr t cr;it i i,rrlt trlj ,t\

\r,1irr.. .,.., r i,.lr.

rta

o ('ltt'ltctcr'sticlrs rlos vnsos lirriiticos:


() Srrt'gc:ttt coro l)c(lr.tcn()s capilirrcs lirrliticos (uc sc
situiutt :to lrtrlo dos calliliu'cs slrgtiincos

o l)osstrcln vrilvrrlas
o Atravcssir'r os linllnoclos
o No h bncstraercs no cnclotclio
o A rrrcrrrllrana trasrl c nruito rlclgaclir
o

.f

unCrcs enclotcliais abcrtas


Exlrernrdade
Caprlar

artertal

sanguneo

Extremidade
venosa

CelLrlas enrJolelrars

'*,7,

Tq,

Frlamenos dLr ancor actn

- \/r\SOS Sr\N(;

i't

X l,lOS:

Sistcrrrir rlc condutos -ccharlos rlrrc tnrnsportin'r o sanqrrc rlo


cot':tito l)iri ()s tccirlo:; c dc vollr l)llri o cot'itito

() litltritlo itttcrsticilrl llcttctrrt no sistcrttii vrtscrrlitr atritvcs r!os


vrsos Iirr litic:os

L'iusi prittcipul rlo lltrxo surtgiittco

Icsistnc,ia clo

o
o

luro sungtiuc,', - i

l)inrctro clos vasos


Viscositltttlc tlo sitlguc

*,,,,nr,

ortthclntctt [o

car.rl

,ft 1;' i,-

'-; ;.

i.Q-t 11r,111

:l

,.: .fr,

aco
.

-./

'.

,f\-{k&,

'
,,.

ffi
f{cgulao do juxo
salrgiiilico c:idull:
o Fiubstincias qunlas 1,,*r,
l\z! er::r rr i s rn
nrn

i,,,,r,,rrlt r' .

.l'ls ucrn:r

r,,, ru i o

gcra! clq q:ir.ru

llr gIUl

vAsos col.roruntos
)I^

conno

'/'r

W*.da'

tf

SQUER.

t)o

AREntA rtr, pttcn


BAo,

lr^i)

toNCO, PEnt{AS

Sfstole:

- pnr.ctk,s r!istcndidas
Ililist*c * r"err'rr'i r,'*r.

.rigi*;rr tr.s

;rurcccs

fl.'-

'r'

.")
llt

))

Ailrcscltil lliior (luittirlarlc


I

rlc'

lccirlo rrrrrsctrllrr liso

:lcvatla rcsislltciir i() luxo sangrinc()


,.tn :r-l:: '.'

'i;,'

{!

lnetvat) pot' I I[rras ncrvosAs nol-a(l t-cn t-gi cs

..

I)ivirlcrtr-sc rt visos lolorcs. is ilttlil l'1r:r'(}llrs. (uc


l)(xlct sc colutricnr rlirctarncntc i inlli vrrrrllr lrtnn,cs dc

Utl \,:tso prc'cl-cltcia

!;r-:-':,.

s\\

artcriovcnos ou shrrnts. so l)c(ucnos


(lUc
ciriis
conccliu s rtcrollrs is vcnrrlas srn
l)issr l)or
c:itp ilarcs
nastonrosc

itpilal'cs:
0ngn

M* W,
!:.WY
llaftir

",girr,

iefr';Iw,

leto;r-

clas nrctartcroIus

As

atrcrtrrras ckrs capilarcs so circuntllclos por cslrrctcrcs


;lrc-capilrrlcs clc rrrirscrrlo liso

[)rnrctro

itrtcrial t Irxtrcnrirlaclc
:xtrcrn irlaclc vcr()Si t)

-5 trutr

lr

pUrr

Slg

I rpxrtuat+'y
''4(t'vdo
"rl,^th f*'t/\'
tfr.nqll

t'

;ij

,(

- *4^tr fl

("' onsti.tri

o -_ alnadil

iriiica

,ei"r{'P

dl'd-

"

"{^a"

wrW

de

clc csilcssirrai
z\

lgrrnrils srrllstricias so c;lpinrlir:; l)or- uirlociosc

cxlrcilosc.

rx. :-,lrl;rst c
"rt\

protcln;rs
(r.Ll.

[.enestr:lircs (]tt lloros :- locais oncle o citplasrna 6a


cellla
eneoteliai tcrna-sc rnais delgatlo riiri -,r,-,,u, cslliCIs"
{ornfirtclqr {) cttpilar porr)s(). :r.: (.l;i;dirlas cndriil"irns,
vrl*sid*rics i*[esti'*is c rcs,ifies d's

'i*s

* Ntl lgllilo.. os eitpilirrcs s-o cxlrcrrr;ri'lr*rrtc


l)or.()\is" o
ctitltlIr'tio
1[*'\rrltinrrir
^
1A& * y yt
(1,1</^ rrntci t &n+ W)lralL
'"
t
^, @';*;'Ntr*l
I
&
o I'crir:i*:i.
11

so cciulas rluc circtrridanr as cc!iilas cncluciiais


ciipilarcs c vlrulll; pris-callilarcs
C)

J)rrssucnI gl'olort*atttcltr.ts (luc ct\,{}Iv,clrr {}s


vso!;
S;io contl"t,e ls

c)

I liicrunl ngcn{cs vastritiivris

(-l

r.os

sntctizarn c Iitrcrain constituintc:; ca nrnnbnana


basal
c e!tr rnatr"lz cxtracclul;rr

fTe

..!

\/'l

o lonrcccr suprirerto norrrral dc sarrguc aos tccidos enr


o

clcscnvolvirncnto
crcscir''rt' btal, in'cia c r(lolcsc.cia

o l)rtrccsstr dt t.t',[g,o
-/o ,.'t,.,1. i
o lirrnniro tlo(cffi,-[it.'et:[1J,is
"6trl^aryrux:J",qlt,
,, ,,4u,,,.i ,
" t ,
,

,-,':;?']rd-/).,

.iii

f ^!,
() l;trnrurito tlc lrovo crrrlorrrc'l'io rrptis lr rrre rrslr.rnrlo
,

/I\

,- c,710(
,' '7
n . ,t.l .',, ,; l1t'-

j,t)11

^i

,\,/

t'VrP
l^
|

!, f{,i}

('rcscirrrcnto tulrroral

/l

'^'t
/)

"

'')-"

Estinruladores

I,-,'17.t)9.

Fator acdico de crescimento ibroblstico (FGF)


FGF bsico
Angiogenina
Fator de crescimento endotelial derivado de plaquetas (pDECGF)
Fator de crescimento do endotlio vascular (VEGF)
Fator dc permeabiliciade vascLrlar (VpF)

ILB

lnibidores
Heparina
Fator plaquetrio 4
Fragmento em 16K de prolactina

3 - Ilcrrrotlirrrrric:r:
o Estuclos ckrs prircpios sicos (rc govcnranr o
sangtinco

1-rclos

vasos c lrclo curao

( lirculao sistmica:

C'rair' -)

artcria

vnulas

-+ vcias -)

('or.ao

"

lluxo

,,

(.)tritrtt() tutilr o cirliblr: rlc


utt vit\()
o {clc icil

{]unrrto lnluor o calihrr dc un \,tis{)


tl

'

t:rcr:irlrr

HilarL{}

srrrgiillelr c l}{'r{El c:ll"u!;lro:

)chlto clrrtli c{): ryulrrrieiirrli: tlc slr!lrii

honlhclirlo pt: Ic e:onrlo rlo illrlir,tlrrr) el

I Cl)(

r'ol rr rrrc/irr i rrrrllr


!ils(

(
I
I

,l

\itllttiile

tr{cpouso I,--' i i irrrilr


l :xi:t'c ic:in illiurso
.l.i ir "i /rrrirr
Icttttin"llgilt !',rarrc ) :: 1.5 i ,/rnin
I

ll_ql-,fff*U_llggUlg_ g14 r' :r d i r r r:_1r ! q s 1-_;1i[ o s


t' nt t o n tl i utl tlq_t_ttttUt_lt

'ill

{.'ct"lirqr
{-'{r I'l

rr:

t t'eirlos
ml

i{

i} t l

l-l
)

i,'"...,".1..
l\ ttt}\- rilr I

t5

( )sso.

| .1"ii,i
{d\

ilr:i* ( tcrnl;rr

lo

{ iui riul n t irctii t!c


( lirrrlrr !it\ ril1)t ;-r crill is
{ }utrcs l"ccirn:i
tr

l(x)
i l{)i}

im

mr
i \t

')t'fi

[]rrlrinlios
it ins
:ir;rritr

li
"-l

:5{)

d.l

-1(,1

50

t\-

,-.

2.

j.5

t75

l(j(i
(

)br . I)rrnrrrlc o

C.\:CI"ClC!() OS ItrLtSr-'riios
1-'t1;....51yl

75 n ,9()'), tlti liu\o sing.rincl {ortiri

I'C,*:Cttt:f =

-;J:i;*i;.,**e*

:tid.,;i*i*liMa

r:;..::l

l.luxo saltgrillcti crlrr.cspondc


tri l)or ul vaso sarrgiilrco i cluuntirl:rclc clc saltgrrc
cl tlc(cnnirr:tdo

(uc

pcrorkr

tcnrpo

clc

velocicracrc

rr. rtrx. sa'gii'co c rrist:'ci.


[lcrc.rricr.
sargrc' cr ,r vas(). crrr
crctcr'rirrad.
lrurirrcr,, ,rc

sc

r*rr1l.

llcr'

t;rr,rrtirtirtrc dc.s:rrrglrrc qrc


rri 1l,r ,rr
vcr.c:irr.trc rrirrrr.i .,,,,
'iso r)cr.r,rccc
rurrrcrr{,
cr, *rrrbrc
;:]'il|:]r..

As trocirs ctc rrrrtriclrtcs. liris


cotl{) o o\iglrio, c a r.etirada
cios cxcrctits ocorrcl cotl
nruitu nrlliclcz nve l clos
capi lancs
sarrgti lrcos

Ilresso

sa

lrgii rrca :

I)r'cssto c

il rr-it (luc o stguc c\rt.c:c


coltll.rt lts llirrcdcs clos
vrsos s.rrgtirrc.s" cirr)az
dc crist'rtrcr. .s u,,rlrr'. itvorccer
passagcrr ckr sarrguc pclos
a
ncsr.ros

.trii'Jllil:l:ca c .
A

nrirrcipal

iir'r

,cs1,c,'s.vcr pera

ilrtursicllrdc

do lluxo sitngtiinco . ciretarnerrte


proporcional i clibrcna
entrc ts prcssircs vigcntes
ns cltras
cxtrcnlicladcs ckrs vasos _l
,

o ()tlittttl0 ir lrrexsiro slrrrgIilrr:ir


t:stii clcyirriir

cl
cl.s
cxtrcrrrid.dcs crc urir vaso
c baix. ,,,, ,,,,t,,,.' ,.,rg,,.'tt
te'cJer
a luir cra cxlr'crrri.lacrc crc arta
prcssr, r)ar.i crc rlaixrr

ifiiil;,,u,'.1,,0',',,

rs dircr.s ctrs *rf ,rs rirs


clu.s

,ffiffiW"ffi*1f
'Jrlen,

-il<ilb*vrvals" {,v

-+ }
@ Wrye Fotra{
*&*fun**y*
n

j
I

ds
f-,,

'

a\

,s-

*/"
{;t

I{csistnci,t t{} uxo

sm{i{}{:{}:

I(csistlrcia c o !{!rto 0ltrc o salsuL (


r.1trc lrr"oclulcr o irirllcdirn*ltto
ao ljuxo

VAS

["*$tlrci {ltxc tictcrnriEtn} ft infcnsid;tq!e


rl* ncsisfmci:r:
j

: i,:illi,Jlllj';ill.,vas{)

"{Yw"2't

(l

C)

w.; a'ffi;a

Viscrlsrtliicle rlo $rI*i


silrrgue

{-

^ W-"'-'lY*

e {lqlm;rr"irrrcn{o do vaso:
o A rcsistncia do 'luxo sansinco r.rirct;unen{c:
1ll'011or'ci'nal ;t' conrtrrrillrc'r' r' \,iso
( t (.)rurrtlo
rttiris colugrr.irlo rr. () \ tso. rrutitll. :;cl.;t

;.

stll)cl cic tlil llitr*ttc visculrit tltrc {cr ii dr:


sg' Ircr-{1.ric{il
grclo rrx. sangrini) , consctllrcritepreptc.

t: atnit. entrc o sargirc e css


;'r'.r.ic

,raor

ser

'ascuritr

)imec{rqr do vaso:

A vcl'cidadc

do rux* .1unto ls parcdcs tr's vas*s

retarr;rci* dcl'iclo i rcsst*r;ia cir..; vas{)sl -rwt,,v


,'\ r'clocirladc ilo Iirxrr sll;r!rirnt,o n;r rugo (:ri.iir-l (ld
Ll. vaso c grnrrclc At Ah,at;m,',Xr-',rxt*
,*',f;he,

1/il"H;
o (Jr*lrrr i'*liis crriihr*s* r.',, r,,,r,,.
rr*ri,r.:":{.ri;
vc:lrciclrclc tkl sing.*e er srir rcgii. ccrrlr;lr
) ( ) rrro silrrgiirrco gtr:lo vi!sci sr:r.;r tlrrct;tt:t*n{e:

1',;.l,r.ci*r;rl r t1-rrilrtir 1i'krrrcilr


F'oisq.-rrilflc

c,lr

rlirrictr.* '. $.ci

rfr"

llr
( cl=-

I) =. l{X} mml lpl

I4

?.1

d ='4

,1 I

tl:

Inll/niilr
i6 rlrl/lnn
25{r nl[/ltr irr

u\ rcsi.ct0tlcilt c illvcrstlltturtc
llJ'{)l'}i}rdional ir6 r!isrctr'
-{
ffi,fp
qry * e,*fi,p

vrso

clu

b,A ,rr*r;yrAA

o Viscositlildc do sangue:
c Quarrto nrais viscos' lr r rq,ido quc tc'ta

uir por
vaso, nraior ser scu atrito cor
A parecre dcsse
vso' e conscqtientctrtelttc. r-'lri.r
scr a rcsistncia

,r

A resist'cia diretame'te prop.rci''ar

clo sangtre

viscosiclacje

o A cr'ccrtrao tros grtibrr.s vcr'rcrh.s (critrticir.os)


r0 sargue 0 principar fut.r da crctcrr'i'ao

viscosidadc saltgtinca
l)olir:itcrnia
ttmcrti cxccssivo
vcrntcrllros no singrrc
y, @v f **y*

dcr gkibulos
ceryig*:a

lnfcr -rcracs cntrc If ,-{ss', Iirrrx' c Iesistlrcia:

prcssiio atua arr,cnta'clo . trx,


quc, rcsistncia tcndc a diminu-lo

F'luxo sangiinco

l'r'csso

sa'giirc',

Iiluro s:rngineo =

llrlro s:rngiinc*

.r

lcsis{nci:r

l>resso
Rcsistnci:r

Lei rlc ltoiscuiilc =

trsllcll-I.fu!Ililf'd

( lonr pri

nr cn

v<Lt&

cnrluantcr

I'resso
Iesistncia

<iri

lo _r l,iscoiitlarle

"

{lonclusires:

/sargline. criret**r.*c
f
,::,..t'rxo
r
prcs1g{atr
rlrrrrctro
* t t'
'r-otr,.rrci,nar
silltltiittt c' irr'r"'r':;,irrcrrrc pr.*trxr.cir*.1
If.t, cotltllrilncllt0
l]."ltt't'
.
c i viscositlilrlc

I - I{egurailo tro fux* samg*nc* pcr*s


fcci*'s:
,*l'rr,yrirt

ynrir,*.^l ,lrW

y/T"u {ryc.

17

+i'j{nr

i
I
I

Controlc tlo uxo dcvitlo a rs


{J} farlrcs :

i-@n=---:\--4
----

\-.S

I)inreLro clirnirrri
1r,
o l)lrrcdc rnrrscular

nlola

nRre

I
I

(lttscrrlo lisg)
e

4r*.hqw a,
lnuilo fortt:

/:*"","i*

r:r.lv.*,':

() nrrrsc*t. l,,';;;,,i;

divcrs,rs tiltos clc cstllnrlos


,
U^Y^YV-$"^ Yy:r,(,1 LO|4,5i
* s,(ri

CAPILARE

----Ygl----*I${ec* n is*, *
ro-r.eg !a o :
* otirrc tllii l'cgrrlao <Jeviclo
r

rn

ar

ncccssidadc cic s*prir'c'tos

Quando rlua*tcracre cre suprr'e'tos


est
-;r"*rilffi
traixa ooffe
arrrirerrlo do l uxo s;urgiine_
t

pa

asl

"Alrrrwrr,

euilndo ? q*anticrade de srrpri*c:rrr.s


cstii arta
cilninuio clo uxo
sangtinccr

F*

oo-r.fl

&!ecanis,*n, ,::^
rfciro rl* Sisfenra. Nrn_v*s*
rrttrrrrrlq}: rJyvr\ l**lrll,, ,Fs
@"i*,Y,*,r;"'tf.hr\('t'l

,E Snais sirtrp:iticos
c parassimnticos
'';":.)^_r,.

N^tprp,
I

"fu

_ w,;::;,d"
ii

t'

h.fr-

vNULA_..--.

g;

*dt;.,n't
:'

, '.'t,ry1'-)

-fr..

xe,r:<j.r>crl
E
:l
Ir

^t[ro

'

- r0Gt]r,A(ro tro FLtixo

Ajustc auto'rticr

d'

sr\N(i{'lruno:

uxo s'rrgii'co por

tcciclo de acortlcl coll suas necessid dcs J,

ffi

deterrrrinacro

ffrr^r"rr\/

I'rincipais causas da auto-regulaiur:


L (cral ,- Nutrio c suprilticnto clc ( ),,
2. [i's -- Neccssitlade dc cxcrcit, tl.s prrtlrr.s
ntctabolismo e clc cletr(llitos
3. Cerebro - Nccessidaclc cle renroo do COr

.),

,{

..is

do

- tr'apel do Oxignio:

9.1'
c

0 luxo siurgtinco
frno

da

arl.eriolar

da nraiuria ikrs tccirlos c c:onrolaclo errr


ncccssicladc dc Oxignio vaso<Jilatao
i

'l'corias busicas:
l. *'llclrr:rntl:r tlc O,.'

As c:clrrllrs tr:cirluiris siluanr_


Sc f)l'r'rxi111i15 is irltcr911S c

cotuliclt:rrt L()t its ttcsllls


por ( ),

--/

h4en io

\ (\
"/-) r.V
):. r-.

r\
Ua
(,)\D
t)( t
1)/'
G

Anre RioLas

ii l prissr,cl
ne

U\;
^--

r-,/ (

(^n l-

\V,
r'\(_,

cessitc de O,

para

pll)llovcr a contrao

\r)

clrrc <l ltrrisculo liscr

!CEL ULAS

DO TECIDO

'.j

,/

iii ('olrr ()s srr;lrirrrcltttrs dc O,

rlilnirruinclo. os

unro,
clilatariar. por nio terenr O,
suicicntc para contrao
IV

A va:;oclilatao 1",r,rrncrue o f
tkl l uxo siurgtilrero c
consccpicntcnrcntc a ol-cila dc
O2 ltaut os tccirlos

*"1

^f,i,F

,,'m, lr- {

"l'fi,

2. "lorrnao de substncias vasrdiratadoras,':


.r.4,

' A trlta clc Oxigttio ttos tecidos. cstinrularia a sntese


clc srrbstois

r
l,,Mp.}a

1!op''1,'
' ;' "
'1'l

,'!r*l-,i.*lcr''.,9

"
_,

_..i;

vas.tlilat.cloras. pclas cclrrlas.

Substrrcias possveis:

a . Atlcttosil -.libcrarlit por cclulus rnuilo.:rtiyls 6u -! t


hiptiricas , ,. -,ffit u' ,- qr..':r.op ,,). i.] ,-L , i ,,, l,** yr*
.ir'.-listarnira.
hci<to lirtico. giis carbric' c K*
lihcrados p()r celulas hipcrativas c causac6res tlc

Vsotlilatao
'-,'-,; fi',;t tl'Offi .'i-,.

9.2 -

1,.i*," ' ,'I,-;3 ,r7-r.,,1,,-,-,


Auto-t-cgulho lro longo pr:tz.o:
,.t.t^q.

;:

d.

'"-t; 'l;lr'!rrr!' 1"'-

,, . #,#";l{0.'l,'L.Strrgirrtcttto tlc t()vos vdi,J-iiri .'iairi{t uccntuatll dos


' 1.VASOS
-,,,;

,..,,1s77;-,*

,3

-, /..;',:.

"

- ,_t,, .- ,-.,i

I i,
/t(l"ptrtti
..ull,'
t",ql

l)rclccsso dcrttoraclt) - scl-altas ; lloscs


Os tccicltts tcttdcltt a aiustal o nrrricro clc vasos siurgtinc6s.
cJc acorclo con as ncccssiclaclcs clc nutricntci. I:x..
rrcccssiclaclc cle O",

l0 - coN'I'tot,Fl

,..

rll

';

7',"1-Q

NFIIVOSO D{) I,-t,tJXO sAN(;('rruuo:


' 'rt:ctll't

!ri'
Alor

:- *;/
\

t,,?

,jtry,^,^,

i;17,r":"i;

4 A-,,r <t,7 f'tt:-JPfii''

,,'p

:',,)'

las

artrias. as :rrterolas e
veias da circulao sistnrica
rcccbcnr r c rv ()s s i rrr ll iil i cos

""a''Rldas

as

l: tlO , t,L,zr.lfr I'rrrrl'(rrru\''

lUlt()

l'lUlllt,vu

&,'..-!'s'^ .-,coltstrittlr dc lttaior irtlcnsidadc


'v6nu,as 'W,tt\cr','ns
/
artcl-iolas c vcias c lnelor
intcnsidadc nas artcrias
..::
;l:
//)i p-7i.t6 t,t-{ .. t. ,t.; ,''','''
ftr*wca*'ti*
4ft
A
t 't ','fu't1,qg rt/4{ ," t t.& ,(u rrv:r-,/z " ",4a.
/:l

_.,.

;:

....

..-,,..;-;;;;;.**n

!0"r -'l'*rus

\/rs;{}('ullsr"iton e!gs tr,ns{)s sisllri**s:

'l'tltts vi'tslrttttlttlr
cstaco niocle riliio

d* vasoor:tr-ii.
Eerrlclo pclos stllrrrlos 111.,1i,-rtrus Xr;mlsrnitirlsis pc!tis
ltetvos
slr:l1r:tie's s.[rrc os \/;sos sa*giirre.s
,A ,,'ts0crtrr:trii$ l)otc sct- iutcll[:r{.ll sc

o Iihi Sirnlr;rticti

aunlr:l"l[ar (} rrUnrcl'{) clc irntrluIsOs trr:rirsrrritrr!(}s


5ir; cl SN Slrli;rtitico tlitllilltnr' o rLr!nuio <.ic
inrpplso:; aSaixg
dti vill.,r" ilor.rnlrl porlcrnos ohscn,irr- v;;sorlilltal

!0'2 *

*lnlp$u"trlci:t do rqrtttrolc rc'\,(!s(I {}s

)striblrio

Si[u;l:cs:

!.

[,.xere

'r,s{)s

cle satlst-tc aos prinr-:illili:i s*trlrcs

ci fsit6 ". .',,*r-.iyu, ]-.1.r.\.::i1. ,i: Jiit;"ri,


l

)rrrun tc o cxcrrc r:io. os i rrrpu l s*s

vsocot"srn(} riiis rlilit-;is

lcgiilc:

snrrgiif ne6s;

rki srsaisrrir

i-, ,,1,

,,. " ;., I i,.i;:

ia,.,, lrrilrl rrzcr


r.r, ctil-llt). *,,qr,,,,r{r
it.
s i,.r.r 1,,it

os visos sitllgliticlls lt'lttsculllt'cs ir:nllr dil;rlados ll';i3


utiIrzao ilrurrcniail:l rlc ()2 (rncciirrisriurs lrir:ili:{)

2. \iitr!rer*s ala tcrntrlrt"ilrlrt col.ltol.ll:

O SN Sirnpirtico lrorie pr()ti()\'*' lltcr-;lircs t() iluxo


sarrgiilrco para pclc. cott o oir iclivtr llc t-Lrg11l;i1.
it

tcni pr:rat

i"l

r"a

crlrllol-al

''clrrtrtcrafur-;t

aumcrrtarla S

rlo

cslnulo
r!ls lr-tcr,olirs rla ;lclc. cr
(t!c iutlcrrlil rl lrrxo siritg[illco lrFrce
itio lur pclut. pcrrlir dc
sirmpr*'rico: l)rolrovcrriro ;r clilata:o

clt lrtr

'F't'En[)cr.:r{ur-lr

riisniliut!er _

)rot"t(i\,cntio it constr-io ckls vis()s


luxri s;rrrglinco para a l.cgiio

cru s-s{f
c lrt

:ilcr

rnnslru sirnlii{iq:cl:

)\

) (llic

t cr

!rtt tt

I *'lllllt

tr{} l){}}lllr;nrn*,ntEl clu.r!;tq..m:

(.)tt;itltlt)

(e

(l-c lr'slo Itrl rislr"i,t

hoiill-rciil (ltlilllitlitrlcs irtsirci:rr{i:s


Illrius os lrrn iIor-ios to c*i.pto
& fl q"e;l

u;st!():

ttillltil.i(. () (.olltr..lttt
,qrnrirr ilir.,} s.ogrr.ir.

(:st.e

ilc

V;t:;ot-.on:;l I !!"ii{)

r'tl itL:l{: tilil r ll;ris. {tii:,


i: ili{cs{lnr )'i l);lll (ill('{)*, {r1rr;1,t., llIlll.r.
cl;l;i {rNtltur.i rcrcllltilu illrru

('()t() pclc" tt{t:icltlos


(:rlt{
'ir

} tutclrll r,

"Ll1l

rr:o llt li'l,lU iirlt

,4" {{r"glll;lu

t-:

ru*x;l rl;r

hl r'c ll lr i s lr r o r los ll:l


r fi

&)$5''iHgHr,,,(}
\ E pBd "q t:
,

\irk-,L

g*c'essft qr

r"r

t){}

lr-l-r.:i.c

l"(l't.ilr

gl I t i r

s,{}[,I

Circuia,r pulrn637

I:

r":;

r&t

1,,

S,,\ :*

{; ,, },i{ }

-_* go,.

u'lltitr:llirr

sisiiiriicll tli:lr'.i :).,


tiil
Verra

\;ll
c;lv;t

li:i:8rjr

Iq1!,,

7%

l\l

rE
' !:

j6

ill'r i

---_
Corao

.1lg

vliititi:c
..1i

gr.16

fiias

3%

Vasos
srslmicos

irifer*r

cii'ciri;rc;l*
,isiirnieli. li I ti;i:.

rtiltiltr

coiuilol'itili {)l,i,i,

ArirlOlas

s
csp,laras .*_

tlt:

7_q;

t itii,lli,'
sli il!1il r. ir( ] t"ll{.t'i
\l

Vr:r;'rg. ygnupgg

i:- '

s;lr(is vr-$Os

.-- 64%

rr,;n.,

\ Cll( t:i():i-

...

Cl."
i

.!.-.:1:

(]uando

c'r:ri.

()c(

c,i,:ill

;::lffl,.],,:1,,,,'':l:l;.,[,:,:l;l:_l:

circrr Iar lronrr;rIlnerrIcr pclos


tccirlos

n 'l'tldo o tcrrit(lrio velloso rnciona


colro re.serv.trri.
slllqtlc - stllll'ilttclt. lttlici.rrirl.
rlc srrrllrc. l).is rrs

cle

ll.r.crlcs
cllls vcilts it;ltcscltlar"r
l)11)llr"icdatlc .'t. ....,u,,rir. er rclirrir. crr
qrrr'rid.rlc clc s.rr1rrc prcscrrrc
r*
'cs1r's[.
As vcias r-cccbcrrr rcrvos iinr1.,,itic:os. circrrl,'
lrzcrrrlo c()r (luc
c.'tr;tirr'r. trirrrscrirrrro o sArgrL.
r)ari o cclr-aa c prri 0s
" otttt'0s vs()s

"
r

l{cscrvlt rir.ios vcnosos:

(Jnalrtlcs vci:rs rllr


l.egio:llrrlrlrrrirr:rl rtislcrrsi-ro c
ctttttrlt0' l)cl'llitirrclo lcscrvr' grirrrtlcs
rltrlptirl.dcs clc

sl.lg,uc

sci's vcrr,s,s rr' g:rtr'

'
curlclrits rlc
lx)ucls

c.ll:ro

r,irriri-l..,

rrrl

crrtrc r.5

itlc

,lror.lrral 2(X) lrrl (


I llrtr,50 rrrll
rl . I)letxos vcltosos tla prlc _ l.cgulao
da tcrrrllcr.lrttrr.ir
c v:lsrs lrrrrnr'rrarcs - sc rrcccssri.r..
c.llticl. lli cil'ctrliti-ur Prrlrrr.',r' p.trc 1r.rtc cr' s['].irc
. .,'',.,,^-,,,,"n,i.,
tltllrits t'cgi,cs scl colPt'orrrctirrrcrilr
tlrr rrrlo

, q i;l

'-i;1-'i,r tr.ar:;

'trlrr.rial"

2-,\tt({(x tt{( t 1L,\(t,io:


.7 ,*'rl.-'.,:
tfl..
o lcsllollsiivci llcl0 lritltsPortc clc
rrrrtricntcs
n

ltcl. rcrrr.i' rr.s 1l..crrit,,s dir cxc'.i,.,

l)c(uLr.is artcrolas

tccid,s-

's

lccirlrs

cllntrolaln o l{r\()

s[t]gtinco l)iri os
c as lrrtiprias c.'dics [cci,t,,.,
cu.ir.tir,'

us
iltrctros tlcst;rs ar.tcrolas
('itrla tccrtlo. corr{rolit
scu ltrtipr.io llrrxo :irn}:rrco
rlc ircor.tk;
r:ot su:ts rrcccssirlltrlcs
cl

l)ir-i

.1.i,it,,,.

- I .wffidih,te;.*..--_J.

..

. :ii'
,,,{
!t

I?"! - fl,,st"uut-,t

q.lil nlic r"{}ci

Meiarterola
fn
| fr . ';'i:={-E:^
I )l

/2

&-*rdrr{"

Arlerrola

s"r"

lr

tilq.ilsr

rlo sis{r't!it

*Canal preerencial

s{{ncter
pr-caPiar

\\
)4::=::=-:;*4
\'+.
-:'
ii=---r'CaPrlaresverdadeiros
\-.^---.

-" " ---"'v)

\-*--

4
' -l-'

\a

6 i\ tuct'()circLrliiq:ilo
rlc ct(!i ()t"Eaio rt
{}rlil iri r:onl ()
qrlticiii o rlr" inlt'il'

is llccss i(ladcs
csl)cclcirs drr

r'q;
//-*:f

==5:ta1-

'\1

l'csnlo

-=-:=r:'====--

> iu'tcl'ii >

lon"nfto

vrtrrlas

(-,t 1li!:r r":

arlcr'ollis

-) vciis >

r:pilirrcs

('or:ac:lr

s A: lc{it.tcl'ioli ts Inrrrtrcr sl() clurrru:rllrs (lc ir{er'oIls rrrurrirrais


c silils c:t itc!ct

i\ti cs cslao cttt"c is ii {c ir}1n..; c c;r1lii;rr r_ts

( iti) tlir'cs
.,j

z\s

ilrtcriolls

L'{lliis ;lnccrcncIltis ;^;.'r-.'l&!,i


cip i lir"cs vc:rrl;trlci ros'n*u.,tvWtt

tr1 l

cscntitr

1cc

rio ll uscu i itl lrbr.uullrrl c

As nrc.artcrolis naro tcin tirnrci nuscrlar corrtrrulr

uitlr

:slle

cr

nx

c-c:irpilar thril tlc rrrrrscrrlo Itsil t;rrc

etrctrt"iriil rl

illil

o s vcllttlls rtlbot'i lctllrr

irr'i tiutic:t tusrul;t i'ici"


clllcirtr:rrlc rl c ((ntt"iir t1rriultlo ncccss:rl-irr

tclti

;r

#
.

As lrrctarlcr'ollts c os csiltclcrcs ltrc-eirllilitrcs loetrlizlurr-st,

llrtix itos it()s cc itltls. o (luc l)ct'ritc tlrrc rtolcs tccirlrrais atrrcrn
tlirctlrnrclrtc sollrc os ncstlos l() contl'olc tlo lrrro slrrgiinco
krcul
latorcs locais cluc attrant sobrc o ltrxo sitgu lnco.
I. Conccntriro ckls nutricntcs
2. Pnrclutos rnais clo nrctabolisnro
3. iotts I l'

12.2

\/asorno l'icitladc:

A contrao ns rnctartcrolas c nos cslnctcrcs pr-c-capilarcs


ocorre conr intcrvalos. o (ue z corn cue o saljguc no lua
dc lrnrrir contnua ltclos capllarcs

[O, i nos iccidos a'cta o grau clc. atrcrturi c bcharncnto


clrts lnctal'lcr'olas c cslnctcl'cs 1tr-c-clrltilarcs

Sc Itii ltlitiot. ttcccssitluclc clc O2 os ltcrorkls dc Lrxg


ttltiorcs
12.3

str

liulriro rndia do sistcrn: cpitar.:

Intcnsiclaclc rncdia dc luxo sangiinero

r
o

l)rcsso c:rltilar nrcdia clcnlnt clos clrpillrr-cs

llttcttsitllrtlc tttcclitt tlc transbrnc:il tlc srrbstnc:ias c'trc


salgLlc tltls cilllilttrcs c o lcluiclu intcrslicial circrrrr juc:cptc

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