ACUTE RENAL FAILURE

Etiologic Factors: Pre-disposing Factors:

Hemmorhage
Age
Hereditary Hypotension
Reduced blood flow Hypovolemia
Gender
Damaged to epithelial
lining of kidney tubules

Glomerular Filtration Rate

(GRF)

Activation of RAAS
(Renin-Angiotension Aldosterone System)

Damaged tubular cells sloughed off into tubules

(Tubular Obstruction)

Necrosis
(Permeability of tubules)

Filtrate absorption

K+ Erythropoietin Affects nervous

Urinary output Blood Pressure system (CNS)
production
Hyperkalemia Depolarization
Metabolic of neurons Oliguria Neuromascular
Heart Failure Decreased
acidosis irritability
immune system
Burning Decreased Pulmonary
Sensation mental acuity edema Involuntary
Anemia
Pain Lethargy jerking and
Numbness twitching
Fatigue
Pallor
weakness