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Remington Pharmaceutical Industry

Origins and Evolution of Pharmaceutical Industry
The modern pharmaceutical industry is a highly competitive non-assembled1 global industry. Its origins can be traced back to the nascent chemical industry of the late nineteenth century in the Upper Rhine Valley near Basel, Switzerland when dyestuffs were found to have antiseptic properties. A host of modern pharmaceutical companies all started out as Rhine-based family dyestuff and chemical companies e.g. Hoffman-La Roche, Sandoz, Ciba-Geigy (the product of a merger between Ciba and Geiger), and Novartis2 etc. Most are still going strong today. Over time many of these chemical companies moved into the production of pharmaceuticals and other synthetic chemicals and they gradually evolved into global players. The introduction and success of penicillin in the early forties and the relative success of other innovative drugs, institutionalized research and development (R&D) efforts in the industry 4. The industry expanded rapidly in the sixties, benefiting from new discoveries and a lax regulatory environment. During this period healthcare spending boomed as global economies prospered. The industry witnessed major developments in the seventies with the introduction of tighter regulatory controls, especially with the introduction of regulations governing the manufacture of generics5. The new regulations revoked permanent patents and established fixed periods on patent protection for branded products, a result of which the market for branded generics6 emerged.

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Brief Introduction
For over 100 years, Remington has been the definitive textbook and reference on the science and practice of pharmacy. This Twenty-First Edition keeps pace with recent changes in the pharmacy curriculum and professional pharmacy practice. More than 95 new contributors and 5 new section editors provide fresh perspectives on the field. New chapters include pharmacogenomics, application of ethical principles to practice dilemmas, technology and automation, professional communication, medication errors, re-engineering pharmacy practice, management of special risk medicines, specialization in pharmacy practice, disease state management, emergency patient care, and wound care. Purchasers of this textbook are entitled to a new, fully indexed Bonus CD-ROM, affording instant access to the full content of Remington in a convenient and portable format. A must-have resource for all in the pharmaceutical industry! With over two decades of serving your healthcare needs and a vision to enhance the quality of life, Remington Pharmaceuticals is committed to providing you with best healthcare solutions. We develop and manufacture pharmaceutical medicines through our dedicated R&D team and state-of-the-art manufacturing facilities to ensure not only a healthier today but also, a healthier tomorrow! Keeping in mind the need for provision of better healthcare services, Remington aims at providing high-class medicines with greater access for the benefit of everyone. The company dedicatedly works towards improving the quality of human life through continuous innovation and hard-work to bring forth a stream of medicinal products that contribute to the betterment of the society. Remington offers a broad portfolio of medicines seeking to give maximum benefit to patients.

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Among the medical professionals and other stakeholders, Remington is best known for its dedicated people, passion for innovation through research and development and quality healthcare solutions. Determined to always go beyond its reputation, the recent development of its new state-of-the-art manufacturing facility is a testimony of our continuous efforts to bring Remington to the global fore.

Company Information
With over two decades of serving your healthcare needs and a vision to enhance the quality of life, Remington Pharmaceuticals is committed to providing you with best healthcare solutions. We develop and manufacture pharmaceutical medicines through our dedicated R&D team and state-of-the-art manufacturing facilities to ensure not only a healthier today but also, a healthier tomorrow! Keeping in mind the need for provision of better healthcare services, Remington aims at providing high-class medicines with greater access for the benefit of everyone. The company dedicatedly works towards improving the quality of human life through continuous innovation and hard-work to bring forth a stream of medicinal products that contribute to the betterment of the society. Remington offers a broad portfolio of medicines seeking to give maximum benefit to patients. Among the medical professionals and other stakeholders, Remington is best known for its dedicated people, passion for innovation through research and development and quality healthcare solutions. Determined to always go beyond its reputation, the recent development of its new state-of-the-art manufacturing facility is a testimony of our continuous efforts to bring Remington to the global fore. With a diligent team and a cGMP compliant, 150,000 sq. ft. manufacturing facility equipped with latest technology, Remington is devoted on ensuring that it delivers and fulfils its commitments to the fullest. Strictly adhering to international

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maintenance and monitoring standards and stringent quality control checks, the company has established an edge over its competitors enabling it to become the industry benchmark. According to the IMS, Switzerland (Q1, 2008), Remington is ranked among the top 30 companies from 681 pharmaceutical companies in Pakistan in terms of unit-wise sales. Here at Remington, we uphold strong moral values and instill them in our team. We inculcate an environment that is based on ethical workings and integrity. The company has also been working towards providing healthcare services to those who are impoverished and in places where they are non-existent. We believe in giving back to the society and for that purpose, the company helped establish Pakistans first private pharmaceutical college and has also been funding a number of NGOs and other non-profit organization such as Red Cross and Ameer Begum Welfare Trust (ABWT). In a world that is rapidly growing, Remingtons dynamic thinking and forwardlooking attitude has made it more adaptable to the changing needs of people. The company envisions growth and partnerships that stretch across the globe. An infrastructure of global standards, a concatenate R&D team, technological advancements, long-lasting customer relationships and a mindset geared towards growth are the key ingredients that are bound to make the company a success in the future as well.

Company Values
Creativity leads to innovation which lays the foundation for success. Innovative and updated technology to produce the best quality products. Utmost care for employees, customers and the society we live in. Respect the employees and their contributions at workplace. Committed to the highest standards of ethics and integrity.

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Teamwork is the lifeblood of the organization. Trust in the relationships with clients.

Message from the C.E.O

I would like to thank everyone who has been directly or indirectly involved in supporting our efforts to make Remingtons name synonymous to trust and quality. It is with the untiring efforts of our Research & Development, Production, Quality Assurance, Material Management, Engineering, Sales & Marketing, Regulatory Affairs, Human Resource and Corporate Finance teams, that we have achieved many valuable milestones in the short history of the Company. Not only Remington, but the whole Pharmaceutical industry in Pakistan is at the crossroads to be counted or to be neglected in the global arena. At Remington we have committed all our energies towards making ourselves a recognized leader in the global pharmaceutical industry by providing quality medicines at an affordable price. The new millennium represents the promise of a better future and the reality of rapid and unpredictable change. To excel, those who will manage, must combine logic with intuition and solid academic training with bold vision. Dr. Khokhar is one of the leading figures in the pharmaceutical sector of the country. He has represented the industry on various national and international forums. He has been elected Chairman of Pakistan Pharmaceutical Manufacturer's Association (PPMA) twice and has been the President of Pakistan Pharmacist Association (PPA), Punjab. He represented PPMA on the Registration and Licensing Boards, Ministry of Health - Pakistan. He has been a member of various national policy making bodies, including the Committee for Monitoring Drugs Sector (CMDS), the Board of Governors of

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Pakistan Medical Research Council (PMRC), the Central Pharmacy Council, the Governing Council of Pakistan Council of Scientific and Industrial Research (PCSIR). He has also been a member of the Pakistan Pharmacopoeia Committee, the National Formulary Committee, the Good Manufacturing Practice Award Committee and the Private Sector Advisory Council - constituted by the Prime Minister of Pakistan. On behalf of the Government of Pakistan and the Company, Dr. Khokhar has attended numerous conferences in North America, Europe and Asia. Over his illustrious career, Dr. Khokhar has also contributed significantly in the education sector of Pakistan. He has been on the Board of Studies and the Board of Faculty of Pharmacy at the University of Punjab. He was nominated a member of the Study Group on Pharmacy Education, by the Higher Education Commission (HEC), Pakistan. He was also instrumental in helping start the first ever private sector pharmacy institution in Pakistan. Dr. Khokhar's contributions are not only limited to the corporate and the education sectors, but also stretch to the field of sports. He is the Life President of Pakistan Gymnastic Federation (PGF) and has always strived to raise the profile of the sport in Pakistan. He has also participated in the activities of the Pakistan Olympic Association, the body which represents Pakistan on the International Olympic Association. Along with his accomplishments in the corporate sector, Dr. Khokhar is recognized as one of the most eminent pharmacists in Pakistan. After completing his B. Pharmacy from the University of Punjab, he completed his MPhil in Pharmacy from the University of Wales. He pursued his doctorate at King's College London, where he joined the Research Group of Professor Arnold H. Beckett - an eminent scientist of world repute. His outstanding contributions during and after his Ph.D. were

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greatly appreciated by his co-researchers, he also authored several research papers in international journals.

Vision and Mission

Remington Pharmaceuticals was established with a vision to enhance the quality of health care services in Pakistan. Today, we have not only become the benchmark in producing superior quality medicines while adhering to the international standards, but we have also contributed significantly in upgrading the healthcare services in many parts of rural and urban Pakistan. Ophthalmology is an expertise area that Remington pharmaceutical now successfully dominates. Our product brand portfolio covers a wide range of therapeutic areas, the major ones being Ophthalmic medicines, Anti-infective, Dermatology and Anti? Ulcerant products According to the data released by IMS (Switzerland) for the first quarter of 2005, Remington Pharmaceuticals is ranked 17th (Unit wise) among the 596 pharmaceutical companies in Pakistan.

Credit to Success
y We conduct ourselves with the utmost Integrity in all our dealings y Good is the enemy of Great. We must strive for Excellence y Innovative thinking leads to out-of-the-box solutions. Always add value! y Perseverance should be a habit. Never ever give up! y People are our guiding beacon. Promptly deliver to their needs

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Trust Regmination
We strive for excellence in every mile we run. Nothing takes our attention more than delivering quality products to doctors, pharmacists and patients. That is why today, Remington is taking care of millions of people trusting our medicines for their wellbeing. Our manufacturing facilities are designed to ensure our commitment to quality at every step of the production process. Computerized building management systems provide required environment round the clock and, in addition to that, extensive equipment automation ensuring Quality by Design. We work hard as a team so that you can be rest assured of getting the highest quality medicine from Remington. Structural Industry Analysis (Porters Five Forces) This section provides a summary positional analysis of the pharmaceutical industry using Porters Five Forces model (see diagram below)

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Barrier to entry: High (Pharmaceuticals). Cost of R&D and patent limitations Industry Competition: High. Advantages gained by first mover advantage (patents) Suppliers: supplier power is low Buyers: buyer power is low Substitutes: low (with patents) medium (after patent expiry) Overall, the pharmaceutical industry shows an upward trend in its core markets. The industry remains highly valued has a favorable market position with strong financial make-up and strong earnings growth. Its future potential demand trend is positive and despite increased competition the industry still shows a continuing upward growth momentum. Datamonitors9 forecast of the leading 16 pharmaceutical companies for 2001 to 2007 suggests that combined sales will grow at a minimum rate of 5.2 percent based on the potential of their product pipeline.

Products
Remington manufactures and markets pharmaceutical drugs. A manufacturing facility equipped with state-of-the-art technology and an extremely competent R&D team ensures that the products provided by the company meet international standards and are of the highest quality. The companys product base covers a wide range of therapeutic areas. We make sure that our medicinal products exactly fulfill the requirements of both physicians and patients. Through continuous innovation, we aim to keep broadening our product mix to serve an increasingly large number of therapeutic areas. We focus on upholding and furthering our brand name and in becoming a market-wide leader in the pharmaceutical industry.

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Products for International Market
Remington manufactures and markets pharmaceutical drugs. A manufacturing facility equipped with state-of-the-art technology and an extremely competent R&D team ensures that the products provided by the company meet international standards and are of the highest quality. The companys product base covers a wide range of therapeutic areas. We make sure that our medicinal products exactly fulfill the requirements of both physicians and patients. Through continuous innovation, we aim to keep broadening our product mix to serve an increasingly large number of therapeutic areas. We focus on upholding and furthering our brand name and in becoming a market-wide leader in the pharmaceutical industry. ANTHELMINITIC GENERIC NAME BRAND NAME Piperazine REMIPAR ELIXIR ANTI-ANAEMIC GENERIC NAME Iron (III) BRAND NAME HydroxideFEMTOL PRODUCT TYPE Syrup PACK SIZE 60ml PACK TYPE Glass Bottle Tablets 10s Blister PRODUCT TYPE Syrup PACK SIZE 30ml PACK TYPE Glass Bottle

Polymaltose Complex Iron (III) Hydroxide PolymaltoseFEMTOL Complex Iron (III) Hydroxide PolymaltoseFEMTOL-F Tablets 10s

Blister

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Complex ANTI-ASTHMATIC GENERIC NAME Ketotifen BRAND NAME ASFEN PRODUCT TYPE Syrup PACK SIZE 60ml PACK TYPE Glass Bottle Ketotifen Montelukast Montelukast ASFEN REMIKAIR 4mg REMIKAIR 5mg / 10mg ANTI-BACTERIAL QUINOLONE GENERIC NAME Ciprofloxacin BRAND NAME ROCIP 500mg Levofloxacin KOBEXIN 250mg /Tablets 500mg Moxifloxacin Norfloxacin Ofloxacin Sparfloxacin OCUMOX BACTINOR CIOF Q-LOX 100mg Tablets Tablets Tablets /Tablets 5s 14s 10s 10s Blister Blister Blister Blister 10s Blister 250mg PRODUCT TYPE /Tablets PACK SIZE 10s PACK TYPE Blister Tablets Sachet 30s 28s 14s Blister Aluminium Blister

4mg / Tablets

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200mg ANTI-BIOTIC / ANTI-INFECTIVE GENERIC NAME Amoxycillin BRAND NAME WISEP PRODUCT TYPE Drops PACK SIZE 10ml PACK TYPE Glass Bottle Amoxycillin WISEP Suspension 60ml Glass Bottle Amoxycillin Amoxycillin Amoxycillin WISEP WISEP-1000 WISEP-DS Tablets Tablets Suspension 100s 10s 60ml Blister Blister Glass Bottle Amoxycillin WISEP-DS Tablets Tablets 20s 6s Blister Blister

Amoxicillin-Clavulanic MAGNICILLIN Acid Amoxicillin-Clavulanic MAGNICILLIN Acid AmoxycillinFlucloxacillin AmoxycillinFlucloxacillin FLOMOXIN FLOMOXIN

Suspension

60ml

Glass Bottle

Capsules

20s

Plastic Bottle

Suspension

45ml

Glass Bottle

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Azithromycin MACRO-AZ Capsules 10s Plastic Bottle Azithromycin MACRO-AZ Suspension 15ml Glass Bottle Cefadroxil DROXIL Capsules 12s Plastic Bottle Cefadroxil DROXIL Suspension 60ml Glass Bottle Cefadroxil Cefadroxil DROXIL-1000 DROXIL-DS Tablets Suspension 10s 60ml Blister Glass Bottle Cefixime ZYLOFIXIM Capsules 5s Plastic Bottle Cefixime ZYLOFIXIM Suspension 30ml Glass Bottle Cefixime ZYLOFIXIM-DS Suspension 30ml Glass Bottle Cephradine ZEFLIN Capsules 12s Plastic Bottle Cephradine ZEFLIN Suspension 60ml Glass Bottle Cephradine ZEFLIN-DS Capsules 12s Plastic

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Bottle Cephradine ZEFLIN-DS Suspension 60ml Glass Bottle Doxycycline Hyclate Fosfomycin Fosfomycin ANTI-CONVULSANT GENERIC NAME Gabapentine BRAND NAME PRODUCT TYPE PACK SIZE 10s PACK TYPE Blister VOXIN MIFOS MIFOS Tablets Capsules Suspension 20s 10s 60ml Blister Blister Blister

NEUROGAB 200mg / Tablets 400mg / 600mg

ANTI-DIABETIC GENERIC NAME Glimepiride BRAND NAME PRODUCT TYPE PACK SIZE 20s PACK TYPE Blister

DIARID 1mg / 2mg /3mg /Tablets 4mg

Glimepiride-Metformin Pioglitazone

DIARID-M 1mg-500mg

Tablets

30s 14s

Blister Blister

XOGLIT 15mg / 30mg /Tablets 45mg

Pioglitazone-Metformin XOGLIT-M 15mg-500mg Pioglitazone-Metformin XOGLIT-M 15mg-850mg

Tablets Tablets

28s 14s

Blister Blister

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ANTI-EMETIC GENERIC NAME Domperidone Domperidone ANTI-HISTAMINE GENERIC NAME Cetrizine Loratidine Loratidine ANTI-OBESITY GENERIC NAME Sibutramine BRAND NAME LOWBEST 15mg ANTI-PEPTIC ULCERANT GENERIC NAME Cimetidine Famotidine BRAND NAME SEMAG TINOPEP 20mg PRODUCT TYPE Tablets Tablets PACK SIZE 10s 20s PACK TYPE Blister Blister 10mg PRODUCT TYPE /Capsules PACK SIZE 14s PACK TYPE Blister BRAND NAME ZINOLUR TILORA TILORA PRODUCT TYPE Tablets Syrup Tablets PACK SIZE 10s 60ml 10s PACK TYPE Blister Glass Bottle Blister BRAND NAME KOMETIC KOMETIC PRODUCT TYPE Suspension Tablets PACK SIZE 120ml 50s PACK TYPE Glass Bottle Blister

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Famotidine Omeprazole TINOPEP 40mg INGIS Tablets Capsules 10s 14s Blister Plastic Bottle Pantoprazole Ranitidine Ranitidine Lansoprazole PANTO RANIFUR RANIFUR-DS ZOXILAN Tablets Tablets Tablets Capsules 14s 10s 10s 14s Blister Blister Blister Plastic Bottle ANTI-RHEUMATIC GENERIC NAME Diclofenac Potassium Diclofenac Potassium Diclofenac Sodium Flurbiprofen Leflunomide BRAND NAME FLAMY 50mg FLAMY 100mg KONAC FLURIBEC RHEUMID 20mg Meloxicam Piroxicam ANTI-VIRAL MELOX 7.5mg / 15mg Tablets KEMROX 10mg / 20mg Capsules 10s 1s Blister Blister 10mg PRODUCT TYPE Tablets Tablets Tablets Tablets /Tablets PACK SIZE 20s 10s 20s 30s 30s PACK TYPE Blister Blister Blister Blister Blister

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GENERIC NAME Ribavrin BRAND NAME PRODUCT TYPE PACK SIZE 10s PACK TYPE Blister

VIROFF 100mg / 200mg /Capsules 400mg

Ribavrin Ribavrin

VIROFF 600mg VIROFF 50mg / 100mg

Tablets Syrup

10s 60ml

Blister Glass Bottle

CARDIOVASCULAR GENERIC NAME Simvastatin-Ezetimibe BRAND NAME PRODUCT TYPE PACK SIZE 7s PACK TYPE Blister

TIMVAST PLUS 10mg-10mg /Tablets 20mg-10mg

Simvastatin-Ezetimibe Rosuvastatin Candesartan Candesartan CandesartanHydrochlorothiazide Clopidogrel-Aspirin

TIMVAST PLUS 40mg-10mg ROSULIP 5mg / 10mg / 20mg KANPRESS 8mg KANPRESS 16mg KANPRESS PLUS

Tablets Tablets Tablets Tablets Tablets

10s 10s 14s 28s 28s

Blister Blister Blister Blister Blister

CEGREL-A 75mg-75mg / 75mg-Tablets 150mg

10s

Blister

Lisinopril-

ZIDOPRIL

Tablets

28s

Blister

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Hydrochlorothiazide Ramipril RAPRIL 1.25mg / 2.5mg / 5mg /Tablets 10mg Amlodipine-Atorvastatin MYODIP 5mg-10mg / 5mg-Tablets 20mg Amlodipine-Atorvastatin MYODIP 10mg-10mg Valsartan ValsartanHydrochlorothiazide ValsartanHydrochlorothiazide COUGH & COLD PREPARATIONS GENERIC NAME Ammonium Chloride BRAND NAME REMISOLE EXPECTORANT DERMATOLOGY GENERIC NAME Benzyl Banzoate BRAND NAME S.P. LOTION PRODUCT TYPE Lotion PACK SIZE PACK TYPE 60ml 120ml /Glass Bottle PRODUCT TYPE Syrup PACK SIZE 60ml 120ml PACK TYPE /Glass Bottle VALZAR PLUS 160mg-25mg Tablets 14s Blister VALZAR 80mg / 160mg Tablets Tablets 10s 14s 28s Blister Blister Blister 7s Blister 28s Blister

VALZAR PLUS 80mg-12.5mg Tablets

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Flucinolone Acetonide CINOL Cream 15gm Aluminium Tube Flucinolone Acetonide CINOL Ointment 15gm Aluminium Tube Flucinolone Neomycin Flucinolone Neomycin Miconazole Nitrate MONITIN Cream 30gm Acetonide-CINOL-N Ointment 15gm Acetonide-CINOL-N Cream 15gm Aluminium Tube Aluminium Tube Aluminium Tube Miconazole Nitrate GYNO MONITIN Cream 20gm Aluminium Tube Miconazole Diflucortolone Polymyxin B. Sulfate-ZincZYLOSPORE Bacitracin Salicylic Acid-Sulphur EAR, NOSE & THROAT GENERIC NAME Betamethasone BRAND NAME BETADROP PRODUCT TYPE Ear Drops PACK SIZE 7.5ml PACK TYPE Plastic Bottle SEPRODERM Ointment 20gm Ointment Nitrate-MONICORT Cream 10gm Aluminium Tube 10gm/20gm Aluminium Tube Glass Bottle

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Betamethasone-Neomycin BETADROP-N Ear Drops 7.5ml Plastic Bottle Chloramphenicol REMICOL Ear Drops 10ml Plastic Bottle Ciprofloxacin-Lignocaine LIGNOCIP Ear Drops 5ml Plastic Bottle Ciprofloxacin OTOCIP Ear Drops 5ml Plastic Bottle Dexamethasone-Ciprofloxacin DEXCIP Ear Suspension Fluticasone Propionate FLUTEX Nasal Spray 15ml 5ml Plastic Bottle Plastic Bottle Gentamicin OPTAGEN Ear Drops 7.5ml Plastic Bottle Gentamicin-Hydrocotisone OPTAGEN-HC Ear Drops 5ml Plastic Bottle LevofloxacinDexamethasone Ofloxacin 0.3% KUNOXY LEFODEX Ear Suspension Ear Drops 5ml 5ml Plastic Bottle Plastic Bottle Ofloxacin 0.6% KUNOXY Plus Ear Drops 5ml Plastic Bottle

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Polymyxin-NeomycinHydrocortisone Acetate Polymyxin B-Lignocaine OTOCAINE POLYSPORE-HC Ear Suspension Ear Drops 5ml 5ml Plastic Bottle Plastic Bottle Sodium Cromoglycate NOSOCROM Nasal Spray 15ml Plastic Bottle Sodium Xylometazoline Tobramycin TOBEC Ear Drops 5ml Cromoglycate-NOSOCROM -X Nasal Spray 13ml Plastic Bottle Plastic Bottle Tobramycin-Dexamethasone TOBEC-D Ear Drops 5ml Plastic Bottle Triamcinolone Acetonide NOSOLONE-AQ Nasal Spray 15ml Plastic Bottle EYE DROPS GENERIC NAME Atropine Sulphate BRAND NAME OPTA ATROPINE PRODUCT TYPE Solution PACK SIZE 10ml PACK TYPE Plastic Bottle Betamethasone BETADROP Solution 7.5ml Plastic Bottle Betamethasone-Neomycin BETADROP-N Solution 7.5ml Plastic

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Bottle Chloramphenicol OPTACHLOR Solution 10ml Plastic Bottle Chloramphenicol-Dexamethasone METHACHLOR Solution 5ml Plastic Bottle Ciprofloxacin ROCIP Solution 5ml Plastic Bottle Dexamethasone OPTADEX Solution 5ml Plastic Bottle Dexamethasone-Neomycin OPTADEX-N Solution 5ml Plastic Bottle Dexamethasone-NeomycinPolymyxin B. Dexamethasone-Sulphacetamide METHASUL Solution 5ml STERIBIOL Suspension 5ml Plastic Bottle Plastic Bottle Dexamethasone-Polymyxin Neomycin Diclofenac Sodium KONAC Solution 5ml B.-POLYDEX Solution 5ml Plastic Bottle Plastic Bottle FlourometholoneTetrahydrozoline Gentamicin OPTAGEN Solution 7.5ml FEMICON Suspension 5ml Plastic Bottle Plastic

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Bottle Gentamicin-Hydrocortisone OPTAGEN-HC Solution 5ml Plastic Bottle H.P.M.C. HICEL Solution 5ml Plastic Bottle Latanoprost PROSTILET Solution 2.5ml Plastic Bottle Latanoprost-Timolol PROSTILET-T Solution 2.5ml Plastic Bottle Moxifloxacin OCUMOX Solution 5ml Plastic Bottle Norfloxacin BACTINOR Solution 5ml Plastic Bottle Ofloxacin CIOF Solution 5ml Plastic Bottle Prednisolone-NeomycinPolymyxin B. Prednisolone Acetate MILDOPRED Suspension 5ml BIOPRED Suspension 5ml Plastic Bottle Plastic Bottle Prednisolone Acetate FORTIPRED Suspension 5ml Plastic Bottle Prednisolone-Chloramphenicol PREDNICOL Suspension 10ml Plastic

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Bottle Prednisolone-Sulphacetamide MYDOSONE Suspension 5ml Plastic Bottle Pyrilamine Phenylephrine Sodium Cromoglycate HISTALYN Solution 5ml Maleate-DECON-A Solution 15ml Plastic Bottle Plastic Bottle Sodium Tetrahydrozoline Sulphacetamide Sodium OPTACID 10% / 20%Solution 30% Timolol BLOTIM 0.25% / 0.5% Solution 5ml 10ml Cromoglycate-HISTAZOLIN Solution 15ml Plastic Bottle Plastic Bottle Plastic Bottle Tobramycin NEBRA Solution 5ml Plastic Bottle Tropicamide MYDROMIDE Solution 5ml Plastic Bottle EYE OINTMENT GENERIC NAME Acyclovir BRAND NAME LOVIR PRODUCT TYPE Ointment PACK SIZE 4.5gm PACK TYPE Aluminium Tube

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Atropine Sulphate MYDRA Ointment 3gm Aluminium Tube Betamethasone-Neomycin BETA-N Ointment 3gm Aluminium Tube Chloramphenicol OPTACHLOR Ointment 5gm Aluminium Tube ChloramphenicolDexamethasone Chlorobutanol T-WET Ointment 3.5gm METHACHLOR Ointment 3gm Aluminium Tube Aluminium Tube Ciprofloxacin ROCIP Ointment 3.5gm Aluminium Tube DexamethasoneSulphacetamide Neomycin - Polymyxin B.STERIBIOL -Dexamethasone OxytetracyclinePolymyxin B. Polymyxin-NeomycinZinc Bacitracin Polymyxin Zinc Bacitracin B.-ZYLOSPORE Ointment 4gm TRIMIN Ointment 5gm XINOXY Ointment 3gm Ointment 3.5gm METHASUL Ointment 3.5gm Aluminium Tube Aluminium Tube Aluminium Tube Aluminium Tube Aluminium Tube

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Polymyxin Zinc Bacitracin B.-POLYSPORE-HC Ointment 3gm Aluminium Tube

Neomycin Hydrocortisone

Prednisolone-Neomycin- BIOPRED Polymyxin B PrednisoloneSulphacetamide Tobramycin NEBRA MYDOSONE

Ointment

3.5gm

Aluminium Tube

Ointment

3.5gm

Aluminium Tube

Ointment

5gm

Aluminium Tube

GASTROPROKINETICS GENERIC NAME Itopride MUSCLE RELAXANT GENERIC NAME Orphenadrine Citrate-Paracetamol NON NARCOTIC ANALGESIC GENERIC NAME BRAND NAME PRODUCT TYPE PACK SIZE PACK TYPE BRAND NAME FLEXODIN PRODUCT TYPE Tablets PACK SIZE 100s PACK TYPE Blister BRAND NAME TOPRID PRODUCT TYPE Tablets PACK SIZE 10s PACK TYPE Blister

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Mefenamic Acid Mefenamic Acid VITAMINS GENERIC NAME Alfacalcidol BRAND NAME PRODUCT TYPE PACK SIZE 10s PACK TYPE Tablet FEBRIN FEBRIN-DS Tablets Tablets 100s 100s Blister Blister

DOLBON 0.25mcg / 0.5mcg /Tablets 1mcg

Thiamine-RiboflavinePyridoxine-Nicotinamide B-Compound Lysine Syrup Antioxidant

PLEXOVIT

Syrup

60ml 120ml

/Glass Bottle /Glass Bottle Plastic Bottle

PLEXOVIT-L

Syrup

60ml 120ml

VitaminsVISAVIT

Tablets

30s

(Beta Carotene, C, E), Mineral (Zn, Cu, Se), Folic Vitamin D Antioxidant VitaminsVISAVIT PLUS Tablets 30s Acid and

Plastic Bottle

(Beta Carotene, C, E), Mineral (Zn, Cu, Se), Folic Vitamin D Multi Vitamin VITONE Syrup 60ml 120ml Acid and

/Glass Bottle

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Multi Vitamin VITONE FORTE Syrup 120ml Glass Bottle Multi Vitamin VITONE FORTE Tablets 20s Plastic Bottle

International Business Licensing & Alliances Various Coutries

We at Remington Pharmaceuticals understand the need for collaborative development and marketing of drugs to achieve higher growth levels. Be that through in-licensing or co-marketing, we seek to enhance our presence both regionally and globally by partnering in areas where we can leverage on our complementary expertise and exploit synergies. Remington Pharmaceuticals is one of the leading pharmaceutical companies in Pakistan and with the commencement of a cGMP compliant, 150,000 sq. ft., multidrug manufacturing facility we are augmenting our presence in the Asian, Middle Eastern and African markets. Built on strong foundations of commitment to excellence, today, Remingtons strong brand has become synonymous to highest standards. Our key strength areas include: y Our teams in-depth know-how and expertise right from rapid drug registrations to generating substantial sales in short spans of time. y Our proven business model and strategic understanding of the markets assist our partners gain forceful market entry across the region.

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y Our successful track record of carrying out R&D, manufacturing quality drugs and the marketing skills of our team puts us in a strong position to successfully execute launches in multiple therapeutic areas. y Our close working relationship with regulatory authorities, medical professionals and other related associations & societies allows us to introduce our partner products on a fast track.

Manufacturing Process
Recognition and Appreciation
Our manufacturing facility boasts enhanced production capacities for Eye and Ear Drops, Ointments, Liquid (Oral) Medicines, Coated and Uncoated Tablets, Capsules and External Preparations for various therapeutic categories. The manufacturing facility is equipped with the latest technology including automated and dedicated process control systems, computerized HVAC/dust control mechanism, computerized Building Management System (BMS) and, processwater and wastewater management systems providing with a ready compliance to cGMP, ISO 9001:2000(E) and ISO 14001. Delegates from Europe and the US have visited and admired the quality standards maintained at Remingtons production facilities. This has led us to formalize transnational relationships and enhance our strategic partnerships.

Contract Manufacturing
Remingtons dedicated and competent R&D team, a state-of-the-art manufacturing plant that meets the highest international standards coupled with the companys vast experience and expertise in Pharmaceutical Manufacturing and its strong ethical

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values ensuring protection of intellectual property rights enable it to provide with a complete outsourcing solution. Using cGMP compliant and regulatory authorities approved manufacturing processes, our production facility boasts enhanced production capacities for Eye and Ear Drops, Ointments, Liquid (Oral) Medicines, Coated and Uncoated Tablets, Capsules and External Preparations for various therapeutic categories. At Remington, an ISO 9001:2000(E) certified company, a planned and systematic pattern of all means and actions is designed to ensure that its products meet the established standard specifications, legal requirements and the organizations quality objectives. Contract manufacturing carries significant advantages some of which include: Low Upfront Cost due to minimal capital requirement and a legal and tax pre being necessary

Flexibility through being able to ramp up production volumes rapidly

Fast-track Processing as a consequence of short lead-team for final production

Access to External Expertise

Greater Adaptability to the ever changing demands of the market allowing fo revenue growth

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The company provides tailored services to meet the clients needs by making available the requested information including the following reports: Inventory levels & movements

Batch monitoring & reports

Quality assurance reports

We strive to create a win-win situation by providing cost-effective and profitable solutions for our partners.

Production Capacity
The annual production capacity of each section running on two 8 hour shifts, which can be extended up to three shifts daily, is as follows: Capsules 30 million capsules

Dry Syrups

12 million bottles

Ear Drops

12 million bottles

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Eye Drops 60 million bottles

Eye Ointments

12 million tubes

Lotions

14 million bottles

Skin Ointments

12 million jars & tubes

Syrups

60 million bottles

Tablets

800 million tablets

Quality by Design
The manufacturing team is committed to produce highest quality products which can meet the needs of both doctors and patients. The team strives to manufacture products that are cost-effective through best utilization of their resources, reduced down-time and by extensively applying planned-preventive maintenance program with coordination of a highly skilled engineering team. Our production facilities meet the regulatory requirements of cGMP and regulatory authorities. All the manufacturing activities are performed according to the approved procedures as required by cGMP and ISO 9001:2000(E) quality management system.

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In addition to quality assurance department's procedures at every stage of production, in-process checks are also imposed, the results of which are continuously monitored and recorded. Materials are procured from approved suppliers through documented procedures, are quarantined until tested and released for use by the manufacturing department. These materials are dispensed under strictly controlled conditions supervised by our Quality Assurance team.

QUALITY ASSURANCE
At Remington the core quality management groups cut across all functional departments to coordinate and monitor the implementation of the quality policy and quality management system. The quality assurance team effectively focuses on each step starting from the raw material souring to packing and storing of the finished products. y Internal Quality Assurance y External Quality Assurance y Effectiveness and Suitability of Quality System Being an ISO 9001:2000(E) certified company, we have extended our efforts to the Total Quality Management Program for the benefit of the organization itself, its members and of the society as a whole. To run the quality system effectively and produce highest standard products, all the required human, material, technical and financial resources are periodically and thoroughly reviewed. The prime objective is the effective management of our operations and substantiation of activities within the organization. These resources include but are not limited to:

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Human Resource Skills
y Design and Development Equipment y Inspection, Testing and Examination Equipment y Instrumentation and Computer Software Here at Remington, a planned and systematic pattern of all means and actions is designed to ensure that our products meet the established standard specifications, legal requirements and the organizations quality objectives.

Collaboration Opportunities Partnering with European / US Companies

For global and specialist pharmaceutical companies looking to enter the Asian, Middle Eastern and African markets, Remington offers its unique platform to partner in these regions. With a vast knowledge of the region, Remington can streamline the difficulties faced when launching a product in the aforementioned regions. Our team is well versed in dealing with geographic areas where lack of information on market trends, healthcare policies and reforms, and local doctors & patients are some of the main challenges. Using our vast experience we successfully tackle these challenges hence de-risking the market entry of our partners products and providing a perfect platform to achieve high growth. We have a step-by-step market entry process that involves initiating the process by carrying out comprehensive top-down market analysis followed by formulating optimal strategies for entering a given market. We appreciate that each partner is unique in its culture and business model; hence we strive to provide customised solutions to contribute to our business partners' success. To share the market entry risks, we also co-invest with our partners.

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In summary, we are interested in sales and marketing partnerships and are keen to explore licensing opportunities to create regional successes. We are not limited by speciality areas and evaluate diverse opportunities to add to our portfolio of products to expand our therapeutic and geographic coverage. Licensing innovative and first time products in the region across multiple therapeutic classes is of particular interest to us. We deal with our partners with highest level of integrity and strive to build longlasting, mutually beneficial relationships that add value for us and for our partners.

Research and Development

Remington Pharmaceuticals has developed one of the most progressed and sensitive R&D facility in the country. The core strength of our team is our foresightedness that enables us to come up with the desired product at the apposite time. The indepth knowledge of the industry, science and the technology help us develop new and effective products for the most pernicious diseases. We have on our R&D team scientists with vast knowledgebase. To keep up with the pace of todays fast growing pharmaceutical industry, the R&D team regularly participates in technical programs and seminars so that they are better able to tackle new challenges and help develop better products. To facilitate the R&D team, Remingtons laboratory is designed and equipped to meet international standards. The R&D team is working on developing multi-therapeutic products pipeline. At Remington Pharmaceutical we are committed to thrive and bring forth new products which will help us in serving the humanity in a more effective way. With a dedicated R&D team and facilities of international standards, we believe that together we will be able to meet the challenges and continue our drive towards progress.

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COMPANYS MARKETING & DISTRIBUTION

Laborate follows push strategy with robust distribution system as follows:

The sale generated by company to distributor is termed as Primary sales. Laborate doesnt believe in advertisement. It has aggressive and vibrant field force to promote their products in the market especially to stockiest, retailers as follows:

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Respnesibility
Valuing the community we live in and the environment has always been an integral part of Remingtons policy. Remington considers itself a part of the community and has always strived to make a difference for the betterment of the wider populace through not only providing quality medicines at affordable prices but also, by giving something back to the community. We have always made sure that our business operations are carried out in a manner that protection of the environment remains one of our top most priorities. Remington is moving towards becoming a carbonneutral company by offsetting its carbon emissions through the deployment of renewable energies for power generation.

Community Support
Remington donates regularly to the NGOs and other foundations to help those who are in dire need so that they can become responsible citizens and equally contribute for the advancement of the country. The company continuously supports non-profit/ charitable organizations like Red Cross and ABWT. The Indian Ocean Tsunami struck in the year 2004 killing millions of people in areas including India, Sri Lanka, Indonesia and Thailand. Remington stepped up for the support of all those affected by what was one of the deadliest natural disasters in history. The company worked with international organizations like the Red Cross to provide both financial aid and medical provisions to the aforementioned tsunamistruck areas. The year 2005, in a time of crisis when the whole country especially the Northern areas were jolted by strong quakes, being a responsible part of the community, Remington was among the first few to extend their full financial and emotional support to the quake-affected people. The company made unrelenting efforts at

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making medical provisions available to those affected and helped in the reconstruction of quake-torn houses. We believe that education plays a vital role in better equipping the youth to make positive contributions to the society as a whole and bringing about development. One of Remingtons keys strengths have been its vast knowledge base and we are committed on empowering our younger generation with that knowledge and more and for that purpose, in the 90s the company helped establish Pakistans very first private pharmaceutical college in Lahore. The college aims at providing quality education and in departing invaluable knowledge to the budding youth of the country. Our senior management team also regularly gives seminars and conducts workshops at local public institutions. We also promote healthy living and encourage people of all ages to engage in sports. Recently Remington held a Polo Tournament for this very purpose. Special training camps were held for younger people so that they make healthy activities a part of their routines from an early age. The team at Remington also actively participated in the tournament which served as an effective means for team-building. Remington has also sponsored a polo team on a number of occasions.

Environment
The world is witnessing increasing globalization with the global markets evolving continuously. Remington not only strives to adapt itself to the changing needs of the world but also, in upholding strong values that inculcate in the team an understanding of the need to protect the environment through clean and efficient means of manufacturing and production. We believe that through a cleaner environment we can better ensure a healthier tomorrow.

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Analysis of Key Industry Participants and Strategy
This section provides a descriptive overview on the top three pharmaceutical firms worldwide.

Pfizer\Pharmacia:
After its merger with Warner-Lambert in July 2000, Pfizer became the worlds largest pharmaceutical company. The strong commercial potential of Pfizers product portfolio and its strong products pipeline, has caused Pfizer to invest heavily in product support, global sales force expansion and increased R&D spend. In April 2003 the merger of Pfizer Inc. and Pharmacia Corporation was announced. The estimated $60 billion merger consolidates Pfizers position as the world's largest pharmaceutical company. The merged entity will control 11% of the global pharmaceutical market, from 8%, with annual revenue estimated to increase from $32 billion to $46 billion. The new Pfizer will also control 50% more of the market than its closest rival, the world's second largest drug company, GlaxoSmithKline10. The European Commission approved the merger but demanded that the firm divest pharmaceuticals in nine different areas in response anti-competitive charges.

GlaxoSmithKline:
The December 2000 merger of GlaxoWellcome and SmithKline Beecham created the GlaxoSmithKline, the world's second largest pharmaceutical company with a global market share of 7%. GSK has global pharmaceutical sales of over $22bn and also the largest share in several therapeutic areas, including the vaccine and overthe-counter products (OTC). However, GSK is still arguably a more global company (in terms of spread) than Pfizer, given that GSK generates a far higher proportion of its sales outside the North American market. GSK is ahead of Pfizer in every other region outside North

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America. GSK generated a relatively high $6.0bn, or 26.6% of its sales, in the European market in the year to September 2002 compared to Pfizer's $3.8bn (16.9%). The region in which Pfizer's market share is closest to GSK's is Africa, Asia and Australasia; this is due mainly to GSKs strong position in the large Japanese market, which has been targeted by Pfizer for future growth.

Merck & Co:

Merck is the third-largest global pharmaceutical company. Excluding organic growth, for Merck to rival the top two it will have to acquire at least one of the 15 leading pharmaceutical firms in the world - a smaller acquisition would not gain it sufficient market share to overtake either Pfizer or GSK. While it has not gone for a full-blown merger, Merck, like other drug companies, has increased the number of collaborations with external and biotech firms. It has so far signed close to 50 deals with research partners in the past 5 years. Merck has also teamed with ScheringPlough to develop respiratory drugs. Merck's strategy is to focus on breakthrough drugs, rather than go the consolidation route or imitate competitors with so-called "me-too" products. Unfortunately its current product pipeline is rather weak and Merck may come under increased pressure to merge as a means of gaining market share and growth. Analysts believe Mercks ideal merger candidate would be Johnson & Johnson due to the little overlap with Mercks pharmaceutical portfolio.

SWOT Analysis and Strategy Review

Since inception in 1849, Pfizer has grown from a small family firm with two employees into a global enterprise with 95,000 employees on six continents. Pfizer has increasingly focused its efforts on R&D and this remains its core business strategy. Pfizers strengths lie in its strong pipeline of innovative pharmaceutical compounds and strong marketing capabilities. Pfizer's performance is characterized

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not only by size, but also by growth. In 1999, Pfizer achieved 20% revenue growth. Pfizer has also set records in each of the past three years to 2003 with the most successful product launches in pharmaceutical history Lipitor, Viagra and Celebrex. Pfizers strength in R&D, marketing, and sales has made them a partner of choice for many companies in the pharmaceutical industry and they are involved in a wide variety of research collaborations and a large number of licensing agreements with universities, institutes and organizations. An outline SWOT analysis of the worlds largest pharmaceutical firm follows next.

Strengths
R&D innovation with a broad therapeutic coverage Marketing strength in major geographical and therapeutic areas Existing Patent protection for a number of years on key products

Opportunities
Decreasing development time through favorable R&D collaborations and internal efforts Emergence of integrated global markets and globalization for new products Co-marketing agreements with companies wishing to capitalize on Pfizer's marketing strengths, providing Pfizer with strong products and therefore revenue growth

Weaknesses
Discontinuation of products in the latter stages of development Co-marketing agreements can limit Pfizer's global presence Increased size and operational complexity makes Pfizer a less agile company

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Threats
Increased competition for core products like Viagra as its high cost encourages use of cheap alternative treatments An increase in the number of safety issues surrounding Viagra Competition from products similar to Pfizer's in R&D that reach the market close to or before Pfizer's products The new economic potential of emergent China, India and competition in diverse regional markets.

Constraints
1. Found a little bit difficulty initially in meeting with the company guide to get the assignments due to his busy schedule. 2. Company didnt want to involve trainees in their business directly. 3. Most of the chemist doesnt provide their Sales information easily.

Strategy adopted:
1. Strictly follow work-timings from 9:00 a. m to 6:00 p.m. 2. Zeal to learn from existing employees. 3. Passion & Dedication towards work to prove myself. 4. Cooperation and assistance to other employees in their work. 5. Effective Communication and presentation skills. 6. Started sending professional-mails to get the assignments and submission of reports of the tasks thus making them (Company guide, Chemists and Retailers) aware the significance of this project in our professional life.

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Critique and Analytical Review of Pfizers Strategy

Pfizer has done quite well historically and analysis has revealed that they are looking to position Themselves strategically for the future. But as we enter a new era in the pharmaceutical industry With increased patent risks and lower marginal product returns, pharmaceutical firms like Pfizer Must restructure their huge organizational mass to reduce structural inefficiencies, cut costs Which is required to enable them compete better in the changing global environment. Due to it Massive R&D push, Pfizer suffers a relatively high rate of discontinuation in pre-approval Products and more focus are required to reduce resource wastage. Pfizers lack of promising Products in its early stage pipeline have left its combined pipeline relatively weaker. This pipeline Deficit will not manifest for a number of years yet, and Pfizer is perhaps well positioned than Most to ensure that it balances its R&D pipeline before it becomes a cause for concern in future. Pfizers imbalanced geographical presence (the US accounts for over 60% of Pfizers market Area) may cause potential geographic limitations and can limit revenue growth should US Demand weakens. While the numbers of co-marketing and collaborative agreements, which Pfizer has established, Are currently proving very favorable, agreements that geographically limit Pfizers activities will Ultimately reduce its long term potential and must be guarded against. Finally, the economic emergence of mass production economies like India and China into the Pharmaceutical fray will require new containment strategies. While this is not an immediate Threat, over time the nature of competition will change and

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the big pharmaceutical firms must Develop strategies to enable them reduce threats and seize the opportunities that are created in Increasingly integrated global markets. Going forwards, I recommend that Pfizer actions a resource\competence based analysis of its Innate capabilities, those characteristics that offer Pfizer distinct competitive advantage over its Industry rivals. There may be a role for using McKinseys 7S Framework to determine the firms Core advantages. On the period of internship I observed Job Descriptions and Responsibilities of the Employees were Multi-tasking. The environment of the workplace is entirely different From the concepts which I studied in books. So I found that to survive in the cut-throat Competitive era we need to develop multi-tasking skills along with dynamic personality And strong communication skills.

Conclusion
The Pharmaceutical industry has a lot of yet untapped potential and it will be interesting to see How the industry matures over the long term. Undoubtedly, the long history and global expertise Of firms like Pfizer, GSK and Merck will stand them in good stated to create and benefit from Emerging global opportunities. Notwithstanding its strengths, complacency must be guarded Against because smaller, agile and innovative firms are on the prowl and all it takes for the small Upstarts are a Superdrug that can change the entire face of the industry. Weve seen it in happen In the Information & Communications industry, for all we know pharmaceuticals may just be Next.

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Recommendations
There are few recommendations from my side which can be beneficial for the company y Employees should be trained according to the changing standards of the Organization. y Company should conduct survey from time to time according to which changes can y Be introduced in the organization to stay updated in the market. y They should introduce creativity into the work, so that the employees can do their Work passionately. y Employees should be more involved in decision making to become more Differentiated.

Leanings from IP:

y Learning beyond classroom y Platform for implementing theoretical concepts y Exposure to corporate culture y Experience under belt y Insight of actual strengths and weaknesses y Developing a network y Refinement of Career goals y Soft skill development y Impart Winning Edge y Feather in the cap as PPO