Drug |nduce |mmune hemo|yt|c

anem|a
emo|yt|c anem|a
W a condlLlon ln whlch Lhere are noL enough red
blood cells ln Lhe blood due Lo Lhe premaLure
desLrucLlon of red blood cells
W Drug|nduced |mmune hemo|yt|c anem|a
ls a blood dlsorder LhaL occurs when a medlclne
Lrlggers Lhe bodys defense (lmmune) sysLem Lo
aLLack lLs own red blood cells
1hls causes red blood cells Lo break down earller
Lhan normal
a drug can cause Lhe lmmune sysLem Lo
mlsLakenly Lhlnk your own red blood cells are
dangerous forelgn subsLances
nt|bod|es Lhen develop agalnsL Lhe red blood
cells 1he anLlbodles aLLach Lo red blood cells and
cause Lhem Lo break down Loo early
W Drugs that can cause th|s type of hemo|yt|c
anem|a |nc|ude
ephalosporlns (a class of anLlbloLlcs)
Levodopa
MeLhyldopa
enlclllln and lLs derlvaLlves
Culnldlne
nonsLeroldal anLllnflammaLory drugs (nSAlus)
W ymptoms
uark urlne
laLlgue
ale skln color
8apld hearL raLe
ShorLness of breaLh
?ellow skln color ([aundlce)
W D|agnost|c exam|nat|on
A physlcal examlnaLlon may show an enlarged spleen A
number of blood and urlne LesLs may be done Lo help
dlagnose Lhls condlLlon
8eLlculocyLes counL(elevaLedrapld desLrucLlon of rbc)
ulrecL or lndlrecL oombs LesL
lndlrecL blllrubln levels
8ed blood cell counL
Serum hapLoglobln decreased(hgb released from
hemolyzed rbc ls bound Lo hapLoglobln)
urlne chemlsLry
W @reatment
SLopplng Lhe drug LhaL ls causlng Lhe problem may
relleve or conLrol Lhe sympLoms
Some persons may be glven a prednlsone Lo
reduce Lhe lmmune response agalnsL Lhe red
blood cells
Speclal blood Lransfuslons may be needed Lo
LreaL severe sympLoms
nurslng dlagnosls
W 8lsk for/ lmpalred skln lnLegrlLy r/L alLered
clrculaLlon resulLlng ln lmpalred oxygen
LransporL Lo Lhe Llssue and skln
prognosls
W MosL paLlenLs have a good ouLcome lf Lhey
sLop Laklng Lhe drug LhaL ls causlng Lhe
problem
W 9oss|b|e Comp||cat|ons
W ueaLh caused by severe anemla ls rare