Figure S1 Histogram of the distribution of zones of inhibition produced by discs containing 10 g erythromycin.

The continuous line represents the 5 point rolling mean, the vertical arrow the peak value assumed for NRI analysis and the vertical dashed line the COWT calaulated from these data.

Fig S2 Histogram of the distribution of zones of inhibition produced by discs containing 30 g moxalactam. The continuous line represents the 5 point rolling mean, the vertical arrow the peak value assumed for NRI analysis and the vertical dashed line the COWT calaulated from these data.

Fig S3 Histogram of the distribution of zones of inhibition produced by discs containing 20 g oxytetracycline. The continuous line represents the 5 point rolling mean, the vertical arrow the peak value assumed for NRI analysis and the vertical dashed line the COWT calaulated from these data.

Fig S4 Histogram of the distribution of zones of inhibition produced by discs containing 25 g trimethoprim/sulfamethoxazole (1:19). The continuous line represents the 5 point rolling mean, the vertical arrow the peak value assumed for NRI analysis and the vertical dashed line the COWT calaulated from these data.

Fig S5 Histogram of the distribution of zones of inhibition produced by discs containing 10 g streptomycin. The continuous line represents the 5 point rolling mean, the vertical arrow the peak value assumed for NRI analysis and the vertical dashed line the COWT calaulated from these data.

Fig S6 Histogram of the distribution of zones of inhibition produced by discs containing 5 g ciprofloxacin. The continuous line represents the 5 point rolling mean, the vertical arrow the best estimate of the peak value.

Fig S7 Histogram of the distribution of zones of inhibition produced by discs containing 5 g enrofloxacin. The continuous line represents the 5 point rolling mean, the vertical arrow the best estimate of the peak value.

Fig S8 Histogram of the distribution of zones of inhibition produced by discs containing 5 g flumequine. The continuous line represents the 5 point rolling mean, the vertical arrow the best estimate of the peak value.

Fig S9 Histogram of the distribution of zones of inhibition produced by discs containing 5 g ofloxacin. The continuous line represents the 5 point rolling mean, the vertical arrow the best estimate of the peak value.