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Written by admin Drug study Feb 6, 2011 Generic Name: Bacillus Clausii Brand Name: Erceflora Classification: Antidiarrheals Suggested Dose: Adults 2-3 vials of 2 billion/5 mL susp Children 2-11 years 1-2 vials of 2 billion/5 mL susp Infants >1 month 1-2 vials of 2 billion/5 mL susp. Mode of Action: Contributes to the recovery of the intestinal microbial flora altered during the course of microbial disorders of diverse origin. It produces various vitamins, particularly group B vitamins thus contributing to correction of vitamin disorders caused by antibiotics & chemotherapeutic agents. Promotes normalization of intestinal flora. Indication: Acute diarrhea with duration of 14 days due to infection, drugs or poisons. Chronic or persistent diarrhea with duration of >14 days. Contraindication: Not for use in immunocompromised patients (cancer patients on chemotherapy, patients taking immunosuppressant meds)
Drug Interaction: No known drug interactions. Side Effects/Adverse Reactions: No known side effects. Adverse Effects: No known adverse effects.
Nursing Responsibility: 1.) Shake drug well before administration. Allows equal distribution of the drug in the fluid it is in. 2.) Monitor patient for any unusual effects from drug. Monitoring allows detection of possible side effects of the drug since there has been no known side effect of the drug. 3.) Administer drug within 30 minutes after opening container. To avoid contamination of the drug. 4.) Dilute drug with sweetened milk, orange juice or tea. To allow easy administration of the drug. 5.) Administer drug orally.
E-Zinc [syr] Indication: E-Zinc is used for the following conditions: As an adjunct in the management of acute diarrhea; to help boost immune function; to help support optimum physical growth and development. Administration: Should be taken on an empty stomach (Best taken at least 1 hr before or 2 hr after meals. May be taken w/ meals to reduce GI discomfort.). Adverse reaction: GI side effects eg nausea & vomiting are seen in doses of elemental Zinc >30 mg. Contraindication: Allergy to any component of E-Zinc. Side effect: Gastrointestinal side effects eg, nausea and vomiting are seen with doses of elemental zinc >30 mg. Mechanism of action: E-Zinc contains zinc. Zinc helps the body's natural defense against damaging free radicals (antioxidant effect) and helps boost immune function. Free radicals are highly reactive and unstable chemicals generated during normal body activities that require oxygen (eg, respiration, digestion, blood circulation, immune system response, etc) and after exposure to ultraviolet (UV) light, cigarette smoke and various pollutants. One major effect of zinc is on the ability of cells to properly replicate the deoxyribonucleic acid (DNA), which is required for cells to multiply. Hence, zinc is needed for normal growth. Zinc has other known functions/effects: Cofactor of various enzymes in cell division and growth. Required for the normal development and maintenance of the immune system; helps regulate the activity of cells involved in immune function. Functions as an antioxidant by being a cofactor of the enzyme superoxide dismutase, which is involved in the removal of harmful free radicals. Zinc is also recommended by the World Health Organization (WHO) and UNICEF as an adjunct in acute diarrhea management together with reduced osmolarity oral rehydration salts (ORS)
Contents Zn sulfate monohydrate Indications E-Zinc is used for the following conditions: As an adjunct in the management of acute diarrhea; to help boost immune function; to help support optimum physical growth and development. Dosage Drops: Therapeutic Dose: As an Adjunct in the Management of Acute Diarrhea together with Reduced Osmolarity ORS: 6 months: 1 mL; <6 months: 2 mL. To be taken orally once during an acute diarrhea episode. Take for 10-14 days even when diarrhea has already stopped.
As Nutritional Supplement: Childn 1-3 years: 0.5 mL; 6-11 months: 0.5 mL. Orally once daily. Missing a Dose: If the patient miss the dose for the day, just take the next dose and the subsequent doses at the usual recommended schedule ie, once a day. Do not double the dose unless recommended. Syrup: Therapeutic Dose: As an Adjunct in the Management of Acute Diarrhea together with Reduced Osmolarity ORS: 6 months: 5 mL or 1 tsp; <6 months: 2.5 mL or tsp. To be taken orally once during an acute diarrhea episode. Take for 10-14 days even when diarrhea has already stopped. As Nutritional Supplement: Adults: 2.5-5 mL (-1 tsp); 9-13 years: 2.5-5 mL (-1 tsp); 4-8 years: 2.5 mL ( tsp); 1-3 years: 1.25 mL ( tsp). Orally once daily. Missing a Dose: If the patient miss the dose for the day, just take the next dose and the subsequent doses at the usual recommended schedule ie, once a day. Do not double the dose unless recommended. Overdosage Rare cases of acute zinc poisoning have been reported. The toxicity signs observed after ingestion of high zinc doses (4-8 g) include nausea, vomiting, diarrhea, fever, metallic taste and lethargy (sleepiness). Advise the patient if he has taken more than the recommended dosage. Administration Should be taken on an empty stomach (Best taken at least 1 hr before or 2 hr after meals. May be taken w/ meals to reduce GI discomfort.). Contraindications Allergy to any component of E-Zinc. Side Effects Gastrointestinal side effects eg, nausea and vomiting are seen with doses of elemental zinc >30 mg. Storage Store at temperatures not exceeding 30C. Description Each mL syrup (oral drops) contains zinc sulfate monohydrate (equivalent to 10 mg elemental zinc) 27.5 mg. Each 5 mL (1 tsp) syrup contains zinc sulfate monohydrate (equivalent to 20 mg elemental zinc) 55 mg. Mechanism of Action E-Zinc contains zinc. Zinc helps the body's natural defense against damaging free radicals (antioxidant effect) and helps boost immune function. Free radicals are highly reactive and unstable chemicals generated during normal body activities that require oxygen (eg, respiration, digestion, blood circulation, immune system response, etc) and after exposure to ultraviolet (UV) light, cigarette smoke and various pollutants. One major effect of zinc is on the ability of cells to properly replicate the deoxyribonucleic acid (DNA), which is required for cells to multiply. Hence, zinc is needed for normal growth. Zinc has other known functions/effects: Cofactor of various enzymes in cell division and growth.
Required for the normal development and maintenance of the immune system; helps regulate the activity of cells involved in immune function. Functions as an antioxidant by being a cofactor of the enzyme superoxide dismutase, which is involved in the removal of harmful free radicals. Zinc is also recommended by the World Health Organization (WHO) and UNICEF as an adjunct in acute diarrhea management together with reduced osmolarity oral rehydration salts (ORS). How Zinc treatment is a simple, inexpensive, and critical new tool for treating diarrheal episodes among children in the developing world. This important micronutrient becomes depleted during diarrhea, but recent studies suggest that replenishing zinc with a10- to 14-day course of treatment can reduce the duration and severity of diarrheal episodes and may also prevent future episodes for up to three months. It is important that the full-course of zinc is taken, and that follow-up and behavior change messages for caregivers are given to ensure full compliance.
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Per tab NaCl 350 mg, Na bicarbonate 250 mg, KCl150 mg, anhydrous glucose 2 g. Per sachet NaCl520 mg, trisodium citrate dihydrate 580 mg, KCl300 mg, anhydrous glucose 2.7 gIndications
Treatment of childn & adults w/dehydrationdue todiarrhea. Replaces fluid &electrolyteslost due to diarrhea &vomiting. Dosage
Tab Reconstitute in water as follows: D eficit therapy (uponrecognition of dehydration) 2 tab/200 mL. Active replacementtherapy (to replenish on going losses at the start of a diarrhea episode or when diarrhea continues after deficit therapy) 1tab/200 mL. Maintenance therapy or for replacement of fluid &electrolyte losses associated w/ vigorous exercise & athletics 1tab/200 mL. Vol (mL) of soln requirement/day: Milddehydration
Adult & childn 30 mL/kg. Infant <2 yr 50mL/kg. Moderate dehydration C hildn 60 mL/kg, infant 100mL/kg. Gr anules Dissolve 1 sachet in every 200 mLwater. Prevention of dehydration w/in the 1st 4 hr C hildn <2 yr - glass (50-100 mL), 2-10 yr -1 glass (100-200 mL), >10 yr As much fluid as they want. T reatment of dehydration <4 mth or <5 kg 1-2 glasses (200-400 mL), 4-11 mth or 5-7.9 kg 2-3 glasses(400-600 mL), 12-23 mth or 8-10.9 kg 3-4 glasses (600-800 mL), 2- 4 yr or 11-15.9 kg 4-6 glasses (800-1200 mL), 5-14 yr or 16-29.9kg 6-11 glasses (1200-2200 mL), 15 yr or 30 kg 11-20 glasses(2200-4000 mL).Administration
Brand Name: PLASIL CLASSIFICATIONS Therapeutic: Antiemetics ACTIONS Physiologic Mechanism Decreased nausea and vomiting. Decreased symptoms of gastric stasis. Pharmacologic Mechanism Blocks dopamine receptors in chemoreceptor trigger zone of the CNS. Stimulates motility of the upper GI tract and accelerates gastric emptying. INDICATION Management of esophageal reflux Treatment and prevention of postoperative nausea and vomiting NURSING CONSIDERATIONS Assess patient for nausea, vomiting, abdominal distention, and bowel sounds before and after administration. May cause drowsiness. Advise patient to avoid concurrent use of alcohol and other CNS depressant while taking this medication. Advise patient to notify health care professional immediately if involuntary movement of eyes, face or limbs occurs.