Q1. The normal autoantibody characterize by all of the following except? A1.has high affinity. Q2.

the memory B cells characterize by all of the following except? A2. Has IgM receptors. Q3. The tetramer assay is used for? A3. Determine the CD4+ and CD8+ cells. Q4. Which of following isnt correct about MBL? Q4. Its collagen tail binds to C1q. Q5. Which of the following isnt a regulator in complement cascade? Q5. Factor B. Q6. Which of the following is not in the predonal cascade (alternative)? A6. C1 inhibitor Q7. Which of the following is not secreted in acute phase response? A7. IL 4 Q8. Which of the following is not a function of complement? A8. Inhibit TH1 Q9. Which of the following is not pro inflammatory? A9. IL10 Q10. In acute phase response the IL1 affect the hypothalamus to produce: A10. Fever Q11. If the c3 is deficient which of the following is most likely to occur? A11. SLE Q12. NK cells in macrophages differ in? A12. Granzyme and perforin mechanism of killing Q13. Which of the following is not apart of chronic inflammation? A13. Increase in neutrophils

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Q14. CpG bind to A14. TLR9 Q15. Which enzyme protects the cytoplasm from respiratory burst enzymes? A15. Catalase Q16. A defect in NADPH oxidase will result in: A16. Chronic granulomatous disease Q17. Which of the following doesnt share in protecting from worm? A17. TH1 Q18.which of the following isnt product by archadonic acid metabolites? A18.histamine. Q19. The receptor that is used by NK to identify the pathogens? A19. KIR. Q20. All about the adaptive immune response is true except? A20. Use pattern recognition molecule. Q21. The enzyme the resemble Membrane Attach Complex? A21. Perforine. Q22. Mutation in Fas-FasL will lead to? A22. Auto Immune Lymphoproliferative Syndrome (ALPS). Q23. Which is the major contributor that changes the acute inflammation to chronic? A23. Inability to remove the pathogen. Q24.the major cytokine released from TH1 is? A24. INF gamma. Q25. If positive TB test which of following isnt true? A25. It might be because of high PPD or the needle is injected subcutaneous. Q26. Which of these cells aren't found in the granuloma? A26. B cells. Q27. The major cell that contribute defense against HBV are? A27. CD8+.
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Q28.what is the most likely to occur due to delayed hypersensitivity reaction? A28.HBV. Q29. Which is not correct about cytokines? A29. Lipid components. Q30. The advantage of ISCOM over the other vaccination techniques is? A30. Deliver the Ag the APC. Q31.WE use skin test for? A31.type I and type IV hypersensitivity reaction Q32.glomeruonephritis is a disease? A32. Can result from nephritis syndrome o nephritis Q33.what is not an action of corticosteroids? A33.inhibit the meyloperoxidase. Q34.which is not a mechanism of developing auto immune disease? A34.intactpreviliged sites Q35.to test the presence of auto AB we use? A35.ELISA or indirect immune fluorescent Q36.the relation between IDDM and HLA DQ is explained as? A36. Inappropriate presentation of insulin on the HLA DQ in the thymus. Q37. The most common symptom of celiac is? A37. Celiac diarrhea. Q38. The AB against endomysel will cause? A38. Celiac disease. Q39. The autoantibody against the transglutamase is in? A39. The celiac disease. Q40. The difference between the graves disease and other type II hypersensitivity is? A40. The autoantibody isnt cytotoxic. Q41. We use coombs test for? A41. Autoimmune hemolysis.
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Q42. Which isnt correct relationship? A42. The graves disease >>>> against thyroid hormones. Q43. The best disease which we can plasmapheresis is? A43. Wegener`s granulomatosis. Q44. To form immunocomplexes the Ag shouldnt be? A44. Monovalent. Q45 farmer lung is? A45. Disease caused by hypersensitivity against mold spores. Q46. In rheumatoid arthritis (RA) the cytokine that caused activation of ostoclast? A46. TNF. Q47. In the treatment of rheumatoid arthritis (RA) and other recently we start to use the blocker of? A47. TNF. Q48. For treatment Multiple sclerosis we use? A48. INF beta. Q49.the presence of rheumatoid factor indicates? A49. Some autoimmune diseases use different mechanism. Q50. The Ag that cause autoimmunity against rheumatoid arthritis (RA)?

A50. Heat shock protein HSP.

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