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Chapter 1: Introduction

In our world today, many diseases are spreading through and through all over. And because of that, many medicines are much more needed as time goes by. But because medicines are matter of life and death, they are made with the high class and expensive components. And because more people are in the lower level in our economic society, that means they are poor and they cant afford such medications. Liver Diseases is one of the most contagious and fatal disease in our world. Liver Disease has many types like Hepatitis, Cirrhosis, Alcoholic Liver Disease and others. Many references stated that 5 million people suffers because of Hepatitis, 4000 Filipinos dies because of Cirrhosis, and ___ dies because of having Alcoholic Liver Disease. Because of these issues, many scientists and medical people are finding a way to address these growing problems. Some has found solutions that can cure those stated diseases but some side effects shows with the use of the medicines made. They are finding a solution which is abundant and has fewer side effects to prolong life. So this pushed the proponents to look for a more efficient and safer medication for many number of Liver Diseases that as we all know, is in demand today. Studying the Cold Ethanolic Extract of Achras zapota Linn. as a Hepatoprotective Agent in Induced Liver Damage Model in Rats. This proposal aims to find a better solution to the increasing problem in Liver Diseases. This will not only lessen peoples suffering from Liver Diseases, it will also decrease our encumbrance, for the fact that the plants leaves will help much in producing a more efficient and has less side effect medicine.

Purpose of the Study


The main objective of this research is to find out if the plant can be an effective and reliable source as well as feasible like the components of the other medicines made for Liver Diseases since this drug is highly in demand today. And because of this, there is a neediness of an alternative and effective substance of the medicine which can be easily found. The aimed outcome of this experimental study is to find an advantage and to bring relief to those nations whose government cant afford to find a more sufficient solution to the increasing number of people with Liver Diseases.

Significance of the Study


The significance of this study focuses on the effectiveness of the use of the Cold Ethanol Extract of Achras zapota Linn. as an alternative and more affordable substance to lessen the effect of Liver Diseases. This study should supply the public a more affordable and convenient medicine that is needed for their maintenance because the prices of many medicines used against Liver Diseases are too expensive and has many side effects that could cause more danger to our health. Since the substance that will be mixed with the medicine will come from a natural matter found in our environmental sources (for this case is the Cold Ethanolic Extract of Ananas comosus leaf), then there is a high possibility that there will be less chemical intake for the persons who will be taking the medicine for their maintenance.

Statement of the Problem


This problem is about the Study of the Cold Ethanolic Extract of Achras zapota Linn. as a Hepatoprotective Agent for Induced Liver Damage Model in Rats. This study will be conducted to lessen the burden of people in buying medicines for Liver Diseases that is expensive and has many side effects.

Scope and Limitations


This study focuses on the probability that the Cold Ethanolic Extract of Achras zapota leaves can be used to make an alternative source of medicine for Liver Diseases. This has no approved therapeutic claims and this is just a supplementary medicine to maintain the normal liver statistics for the patients. The scope of this research only focuses on the substances that can be found on the leaves of Achras zapota that can treat Liver Diseases. Any other plants that can also be a replacement for the components of the medicine for Liver Diseases will not be discussed in this study. The limit of this research focuses only on the types of Liver Diseases. Any other liver-related diseases will not be discussed in this study.