DNB MEDICINE Q PAPERS (January 2000- June 2010)

DNB MEDICINE (January 2000 - June 2010) June 2004 missing

SYSTEMWISE QUESTIONS
CARDIOLOGY 1. 2. 3. 4. 5. Pathophysiologic basis of management of congestive heart failure (Jan 2000) Pulseless ventricular tachycardia(Jan 2000) Non-cardiogenic pulmonary edema(Jan 2000) Serum cardiac markers(Jan 2000) Discuss pathophysiology, risk factors and prevention of coronary artery disease (June2000) 6. Ventricular aneurysm (June 2001) 7. Diagnosis of pulmonary embolism (June 2001) 8. Treatment of stable angina (June 2001) 9. Discuss pathology, pathophysiology, c/f, investigations of HOCM (June 2001) 10. Managemnt of unstable angina (Dec 2001) 11. DCM (Dec 2001) 12. Prevention of sudden cardiac death (Dec 2001) 13. Antiplatelet agents(Dec 2001) 14. Risk factors of IHD in Asian male (June 2002) 15. Describe the conduction system of heart. Outline the AV conduction disturbance, their diagnosis, management (June 2002) 16. Clinical features, Management of acute myocarditis (Dec 2002) 17. Therapeutic strategies in unstable angina current concept (Dec 2002) 18. Pharmacological stress in cardiology, their indications (Dec 2002) 19. Valsalva maneuver (June 2003) 20. Describe in detail diagnosis and management of acute myocardial infarction in first 24 hours? (June 2003) 21. Key messages of JNC VII (Dec 2003) 22. Discuss pathophysiology and management of paroxysmal supraventricular tachycardia (Dec 2004) 23. Define prehypertension and prediabetes. Compare JNC 6 and 7 guidelines in tabular form (Dec 2004) 24. Discuss indications and contraindications of cardiac transplantation (June 2005) 25. Risk stratification in patient with acute coronary syndrome (June 2005) 26. Junctional tachycardia (June 2005) 27. Obstructive sleep apnoea (June 2005)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

28. Discuss preoperative evaluation of a patient for non-cardiac surgery (June 2005) 29. Stem cell therapy for ischemic heart disease (June 2005) 30. Vascular endothelial dysfunction (June 2005) 31. Diagnosis and management of infective endocaditis (Dec 2005) 32. Cardiac pacing (Dec 2005) 33. Management of UA/ NSTEMI (Dec 2005) 34. Refractory heart failure (June 2006) 35. Atrial fibrillation (June 2006) 36. Diagnosis of infective endocarditis (June 2006) 37. Diagnosis of rheumatic heart diseases (Dec 2006) 38. Management of ventricular arrhythmias (Dec 2006) 39. Long QT syndrome (Dec 2006) 40. Osdtructive sleep apnoea (Dec 2006) 41. Assessing cardio-metabolic risk for metabolic syndrome (June 2007) 42. Sirolimus (June 2007) 43. Prosthetic valve endocarditis (June 2007) 44. Management of suuupraventricular arrhythmias (June 2007) 45. Treatment of refractory heart failure (Dec 2007) 46. Recurrent palpitations: approach and diagnosis (Dec 2007) 47. Right sided endocarditis (Dec 2007) 48. Describe cardiac pacing types, indications and complications (June 2008) 49. Wolf Parkinson White syndrome (June 2008) 50. Right ventricular infarction diagnosis, management and complications (June 2008) 51. Current status of coronary stents and its safety issues (Dec 2008) 52. Management of post myocardial infarction tachyarrhythmias (Dec 2008) 53. Write about the effect of pregnancy on valvular heart disease (June 2009) 54. Current status of myocardial markers (June 2009) 55. Recent advances in cardiac imaging (June 2009) 56. Conducting system of the heart (June 2009) 57. Enumerate various causes of pericarditis. How will you differentiate between restrictive cardiomyopathy and constrictive pericarditis? Describe the management of constrictive pericarditis (Dec 2009) 58. Describe the pathophysiology and haemodynamic consequences of ventricular remodeling (Dec 2009) 59. Enumerate various cyanotic heart diseases. Describe the clinical features and management of a patient with fallots tetralogy (Dec 2009)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

60. Clinical presentation, diagnostic evaluation and management of right ventricular infarction 61. Clinical features and management of cardiogenic shock (June 2010) 62. Pathophysiology, diagnostic evaluation and treatment modalities in primary pulmonary hypertension (June 2010) 63. Enumerate acyanotic congenital heart diseases and describe in brief the clinical features, diagnostic evaluation and treatment of ventricular septal defect (June 2010) PULMONOLOGY 1. Mycoplasma infection of lower respiratory tract (Jan 2000) 2. The etiology and pathogenesis of chronic cor pulmonale. Describe the hemodynamic abnormalities. (Jan 2000) 3. Discuss the etiology and pathogenesis of chronic cor pulmonale. Describe the hemodynamic abnormalities (June 2000) 4. Risk factors and management of acute respiratory distress syndrome (June 2000) 5. Leukotriene antagonists (June 2000) 6. Pathophysiology of ARDS (Dec 2001) 7. BAL (June 2002) 8. Diagnosis, treatment of idiopathic pulmonary fibrosis (June 2002) 9. Atypical pneumonia (June 2002) 10. Allergic bronchpulmonary aspergillosis (Dec 2002) 11. Pulmonary infiltrates (Dec 2002) 12. Invasive aspergillosis (Dec 2002) 13. Cardiac biomarkers (June 2003) 14. Describe briefly various causes of hypoxia. Discuss the benefits, principles, amd modes of use of long term oxygen therapy in a patient with advanced chronic obstructive pulmonary disease (Dec 2003) 15. Describe the etiopathogenesis and management of nosocomial pneumonias (Dec 2004) 16. SAARS (Dec 2004) 17. Pleural fluid analysis (Dec 2004) 18. What are GOLD guidelines for COPD (Dec 2004) 19. Discuss management of community acquired pneumonia (June 2005) 20. Management of chronic persistent asthma (Dec 2005) 21. Alpha 1 antitrypsin deficiency (Dec 2005) 22. Spirometery (Dec 2005) 23. Management of ILD (Dec 2005)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

24. Describe causes, diagnosis and management of ARDS (June 2006) 25. Pulmonary illness with eosinophilia (June 2006) 26. Sleep apnoea syndrome (June 2006) 27. COPD diagnosis and management (Dec 2006) 28. Pulmonary vasculitis (June 2007) 29. Management of acute severe asthma (June 2007) 30. Obstructive sleep apnoea (June 2007) 31. Cardiovascular drugs induced lung diseases (June 2007) 32. Clinical features and management of obstructive sleep apnoea (Dec 2007) 33. Pulmonary thromboembolism (Dec 2007) 34. Pathophysiology of ARDS (Dec 2007) 35. Hepatopulmonary syndrome (June 2008) 36. Describe the technique of bronchoalveolar lavage and its applications (June 2008) 37. Solitary Pulmonary Nodule - investigational approach (Dec 08) 38. Describe GOLD staging, risk factors and the role of non pharmacological therapies in COPD (Dec 08) 39. Sleep apnea syndrome (June 2009) 40. Define hypersensitivity pneumonitis and eosinophilic pneumonia. Describe hypereosinophiic syndrome and principles of its management (Dec 2009) 41. Describe the clinical features, diagnosis and principle of management as well as preventive measures of acute pulmonary embolism (Dec 2009) 42. Describe the role of inflammatory mediators in bronchial asthma. Enumerate the various ne drugs available for the treatment of bronchial asthma (Dec 2009) 43. Describe the surface anatomy of lung. Enumerate various bronchopulmonary segments and their clinical significance (Dec 2009) 44. ARDS definition, causes and approach to its management (June 2010) 45. Clinical features of idiopathic pulmonary fibrosis and its management (June 2010) 46. Describe pulmonary function tests and their interpretation in relation to various pulmonary diseases (June 2010) NEUROLOGY 1. Discuss recent advances in diagnosis and management of stroke (Jan 2000) 2. Acute confusional state(Jan 2000) 3. Classify seizures. What are the drugs used in serious disorders? Outline their toxicity(Jan 2000) 4. Trigeminal neuralgia (june 2000) 5. Describe early diagnosis and management of acute ischemic stroke(June 2000)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

6. Describe the clinical features and diagnosis of acute inflammatory demyelinating poly neuritis. & current trends in the management (June 2001) 7. Toxoplasma infection of CNS (June 2001) 8. C/f , diagnosis of high cervical cord compression (Dec 2001) 9. CIDP (Dec 2002) 10. Causes of ischemic stroke, describe management plan for a pt presenting with acute stroke (Dec 2002) 11. Discuss briefly the pathogenesis of migraine, with special reference to its pharmacological basis. Outline the therapeutic approach to a pt getting 3 to 4 attaks per month of acute migraine of moderate severity (Dec 2002) 12. Diagnosis of brain death (Dec 2002) 13. Entrapment neuropathies (June 2003) 14. Magnetic resonance Angiography (June 2003) 15. Management of refractory seizures (Dec 2003) 16. Discuss the management of ischemic cerebral stroke within two hours of onset (Dec 2003) 17. TIA (Dec 2004) 18. Thrombolytic therapy in acute stroke (Dec 2004) 19. Describe formation, functions of CSF and alterations in diseases (Dec 2004) 20. Describe pathogenesis and treatment of parkinsonism (Dec 2004) 21. Discuss management of acute ischemic stroke in a patient presenting within 3-6 hours (June 2005) 22. Discuss briefly evaluation of adult patients with seizures (June 2005) 23. Neuroleptic malignant syndrome (June 2005, Dec 2007) 24. Transient global amnesia (June 2005) 25. Meningococcal meningitis (June 2005) 26. Chronic meningitis (Dec 2005) 27. Evaluation of patient of febrile encephalopathy (June 2006) 28. Seizures in a patient with HIV infection (June 2006) 29. Internuclear ophthalmopathy (June 2006) 30. Blood supply of brain and its importance in localization of site of stroke (June 2006) 31. Medical conditions causing daytime sleepiness (June 2006) 32. Slow virus disease (June 2006) 33. Myoclonic seizures (Dec 2006) 34. Thrombolytics in acute ischemic stroke (Dec 2006) 35. Parkinsons disease (Dec 2006) 36. Circle of willis and clinical importance (Dec 2006)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

37. Management of painful neuropathy (June 2007) 38. Paraneoplastic neurologic syndromes (June 2007) 39. Weils syndrome (June 2007) 40. Recent advances in management of stroke (June 2007) 41. Sensory tracts in spinal cord and various sensory syndromes (June 2007) 42. Pain management (June 2007) 43. Brain abscess (Dec 2007) 44. Channelopathies (Dec 2007) 45. Posterior circulation stroke (Dec 2007) 46. Pharmacological management of multiple sclerosis (Dec 2007) 47. Cortical venous thrombosis; risk factors, clinical features and management (June 2008) 48. Single ring enhancing lesion of brain (June 2008) 49. Diagnostic criteria and management of GBS (June 2008) 50. Narcolepsy (Dec 2008) 51. Pseudotumour cerebri (Dec 2008) 52. Describe cerebral circulation. Discuss the pathophysiology and clinical manifestations of small vessel infarct (Dec 2008) 53. Management of refractory epilepsy (June 2009) 54. Describe briefly various pharmacological treatment approaches of alzheimer disease (June 2009) 55. Describe briefly the motor feature of Parkinsons Disease (June 2009) 56. Discuss the etiology , clinical features and management of cortical venous thrombosis (June 2009) 57. Prion diseases (June 2009) 58. Classify ataxia disorders. Mention about treatable ataxia. How will you approach a patient presenting with ataxia (Dec 2009) 59. Clinical features, diagnostic evaluation and management of neurocysticercosis (June 2010) 60. Causes investigations and management of acute polyneuropathy (June 2010) 61. Anatomy of cortical venous sinuses and outline the management of cavernous sinus thrombosis (June 2010) GIT & LIVER 1. Discuss the epidemiology, clinical features and management of hepatitis C virus infection (Jan 2000) 2. Prognostic factors in acute pancreatitis (Jan 2000)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

3. 4. 5. 6. 7. 8. 9.

Serum and tissue markers in Hepatitis B viral infection (jan 2000) Diagnosis and prognostic indicators in acute hemorrhagic pancreatitis (june 2000) Hepatorenal syndrome Indian scenario (June 2001) Spontaneous bacterial peritonitis (June 2001) Pathogenesis & diagnosis of sub acute hepatic failure (June 2001) Hepatic enzyme induction (June 2001) Discuss the etiopathogenesis of chronic hepatitis. Describe the clinical features, diagnosis & management of chronic hepatitis B (Dec 2001) 10. IBD, classification & distinguishing features(Dec 2001) 11. Atypical GERD (June 2002) 12. Antiviral therapy in chronic hepatitis (June 2003) 13. H. pylori (Dec 2003) 14. Pancreatic neuroendocrine tumors (Dec 2004) 15. Secretory diarrhea (Dec 2004) 16. Diagnosis of malabsorption syndrome (Dec 2004) 17. Asymptomatic hyperbilirubenemia (Dec 2004) A. Chronic diarrhea; B. Frostbite (June 2005) B. Erectile dysfunction; B. Refractory ascites (June 2005) 18. Management of acute gastrointestinal bleeding (June 2005) 19. Non Alcoholic Steato Hepatitis (NASH) (June 2005) 20. Hepatopulmonary syndrome (Dec 2005) 21. Approach of lower GI bleeding in elderly (Dec 2005) 22. Drug therapy of chronic hepatitis B (Dec 2005) 23. Refractory ascitis (Dec 2005, Dec 2006) 24. Indications and management of liver transplantation (June 2006) 25. Management of acute liver failure (June 2006) 26. Granulomatous hepatitis (June 2006) 27. Microscopic colitis (Dec 2006) 28. Diabetic nephropathy (Dec 2006) 29. Artificial liver support (Dec 2006) 30. Diagnostic approach to abdominal tuberculosis (June 2007) 31. Evaluation of malabsorption (June 2007) 32. Management of gastrointestinal hemorrhage (June 2007) 33. Non-alcoholic steatohepatitis (June 2007) 34. Autoimmune hepatitis (Dec 2007) 35. Extraintestinal manifestations of ulcerative colitis (Dec 2007) 36. H. Pylori induced diseases and their treatment (Dec 2007)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

37. Role of probiotics in diseases of gut (Dec 2007) 38. Febrile jaundice: causes and investigations (June 2008) 39. Galactorrhoea (June 2008) 40. Selective gut decontamination (June 2008) 41. Predictors of severity of acute pancreatitis (Dec 2008) 42. Discuss the clinical features , diagnosis and managemant of Wilson,s disease (June 2009) 43. Discuss the pathophysiology , clinical features and diagnostic tests for gastroesophageal reflux disease (June 2009) 44. Management of chronic hepatitis B (June 2009) 45. Drug induced liver injury (June 2009) 46. Chemoprevention of colorectal cancer (June 2009) 47. Describe the cause and diagnostic evaluation of a patient with chronic diarrohea (Dec 2009) 48. What are the types of viral hepatitis? Write down characteristic features of hepatitis c illness and its current line of management (Dec 2009) 49. Describe bilirubin metabolism. What is the differential diagnosis of obstuctive jaundice? Describe the diagnostic approach to a 40 yaers old female with obstructive jaundice (Dec 2009) 50. Abdominal tuberculosis types, clinical presentations and diagnostic evaluation (June 2010) 51. Immunopathogenesis of hepatitis B infection and management of chronic hepatitis B (June 2010)

INFECTIOUS DISEASES 1. 2. 3. 4. 5. 6. 7. 8. 9. Bartonellosis (Jan 2000) Management of multidrug resistant falciparum malaria (June 2000) Clinical features and diagnosis of leptospirosis (June 2000) Newer vaccines in infectious diseases (June 2001) Toxoplasma infection of CNS (Dec 2001) Diagnosis & management of visceral leshmaniasis (Dec 2001) Botulinum toxins & its therapeutic value(Dec 2001) Epidemiology of plague (June 2002) Describe clinical fatures, investigation and therapy for severe falciparum malaria (June 2003) 10. Dengue shock syndrome (Dec 2003)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

11. Post exposure prophylaxis of rabies (Dec 2004) 12. Enumerate the drugs name , doses and toxicity used for resistant cerebral malaria. Mention complications of cerebral malaria (Dec 2004) 13. Hemorrhagic fever (Dec 2005) 14. Slow virus disease (June 2006) 15. Severe falciparum malaria (June 2006) 16. Infections in health care workers (June 2006) 17. Leptospirosis (June 2006) 18. Malarial hepatopathy (Dec 2006) 19. Dengue fever (Dec 2006) 20. Chikunguniya fever (June 2007) 21. Complications of falciparum malaria (June 2007) 22. Viral haemorrhagic fever (Dec 2007) 23. Tropical pyomyositis (Dec 2007) 24. Post-exposure prophylaxis of rabies (June 2008) 25. Management of Dengue Shock Syndrome (Dec 2008) 26. Chikungunya arthritis - pathogenesis and management (Dec 2008) 27. Management of severe and complicated malaria (June 2009) 28. Describe the etiopathogenesis, clinical features and diagnostic evaluation of a patient with leptospirosis (Dec 2009) 29. Describe the clinical features, epidemiology and management of a patient with filariasis (Dec 2009) 30. Clinical presentation, sequelae and management of herpes zoster (June 2010)

NEPHROLOGY 1. Discuss diabetic nephropathy with reference to its stages, diagnosis and management(Jan 2000) 2. Hepatorenal syndrome(Jan 2000, Dec 2003, Dec 2004) 3. Classification of glomerulonephritis and approach to diagnosis (June 2001) 4. Renal tubular acidosis (June 2001) 5. Discuss the etiology, predisposing factors, prevention, & management of ARF in the tropics (Dec 2001) 6. ANCA associated renal diseases (Dec 2001) 7. Renal osteodystrophy, pathophysiology & diagnosis (June 2002) 8. CAPD (June 2002, Dec 2004, June 2007) 9. Therapeutic apharesis (June 2002)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

10. Renal artery stenosis (June 2002) 11. Analgesic nephropathy (Dec 2002) 12. Renal invovement in DM (June 2003) 13. Renal Replacement therapy (Dec 2003) 14. Diabetic nephropathy (Dec 2003) 15. Anemia in chronic renal failure (Dec 2003) 16. Management of lupus nephritis (Dec 2004) 17. NSAID induced nephropathy (Dec 04) 18. Treatment of renal hypertension (June 2005) 19. Hemolytic uremic syndrome (June 2005, Dec 2005) 20. Total Renin Angiotensin Aldosterone System (RAAS) blockade (June 2005) 21. Diagnosis and management of rapidly progressive renal failure (Dec 2005) 22. Evaluation of patient with chronic kidney disease (Dec 2005) 23. Sterile pyuria (Dec 2005) 24. Diagnosis and management of acute tubular necrosis (June 2006) 25. Lupus nephritis (June 2006) 26. Xanthogranulomatous pyelonephritis (Dec2006) 27. CAPD catheter insertion and management of complications (Dec 2006) 28. Plasmapheresis (Dec 2006) 29. Drug induced nephropathy (Dec 2006) 30. Diabetic nephropathy (June 2007) 31. Hepatorenal syndrome: pathophysiology and management (Dec 2007) 32. Lupus nephritis: diagnosis and management (Dec 2007) 33. Acute respiratory failure: approach and management (Dec 2007) 34. Plasmapheresis: role in clinical medicine (Dec 2007) 35. Postkidney transplantation infection (Dec 2007) 36. Drug induced interstitial nephritis clinical features, lab. Diagnosis and management (June 2008) 37. Fanconis syndrome (June 2008) 38. Microalbiminuria: definition and clinical implications (June 2008) 39. Discuss clinical features, staging and treatment of lupus nephritis (Dec 08) 40. Discuss the evaluation of a patient with acute renal failure (June 2009) 41. Management of membranous glomerulonepheritis (June 2009) 42. Describe steroid resistant nephrotic syndrome and its management (Dec 2009) 43. Classify lupus nephritis and outline its management (June 2010) 44. Renin angiotensin system and its role in health and disease (June 2010)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

45. Enumerate nephrotoxic drugs and describe in brief heir mechanism of toxicity and principles of dose modifications in chronic kidney diseases (June 2010)

RHEUMATOLOGY 1. 2. 3. 4. Lipoprotein a (LP-a) (Jan 2000) Extra-articular manifestations of Rheumatoid arthritis (June 2000) Mysthenic crisis (June 2001) Describe the etiopathogenesis, Diagnosis, assessment of disease activity and principles of managent of SLE (June 2001) 5. Rheumatoid arthritis : Current status of management including recent advances (Dec 2001) 6. Hyperhomocysteinemia (Dec 2001, Dec 2007) 7. Describe the etiopathogenesis , c/f, management of antiphospholipid antibody syndrome (June 2002) 8. Activated protein C (June 2002) 9. Raynauds phenomenon, classification & therapeutic approach (June 2002) 10. Reactive spondyloarthritis(June 2002) 11. Describe the etiology, pathology, diagnosis, recent trends in management of rheumatoid arthritis (Dec 2002) 12. Myasthenia gravis, etiopathogenesis and management (Dec 2002) 13. Renal involvement in SLE (Dec 2002) 14. Rhabdomyolysis (Dec 2002) 15. Criteria for diagnosis of SLE (June 2003) 16. Role of hyperhomocysteinemia in vascular disease and its treatment (June 2003) 17. Describe etiopathogenesis, clinical features, management of Rheumatoid Arthritis? (Dec 2003) 18. Reactive arthritis (Dec 2004) 19. Describe and classify amyloidosis. Enlist features of amyloidosis. How would u confirm diagnosis (Dec 2004) 20. Name systemic vasculitides. Which conditions mimic vasculitis (Dec 2004) 21. Diagnosis and treatment of ankylosing spondylosis (June 2005) 22. Discuss current management strategies in osteoporosis (June 2005) 23. Myasthenia crisis (June 2005) 24. Diagnosis and management of myesthenic crisis (Dec 2005) 25. Psoriatic arthritis (Dec 2005) 26. Classification and management of systemic vasculitis (June 2006)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

27. Antineutrophilic cytoplasmic antibodies (June 2006) 28. Henosch Schonlein purpura (June 2006) 29. Disease modifying anti rheumatoid drugs (June 2006) 30. Antiphospholipid antibody syndrome (June 2006, Dec 2006) 31. Raynods phenomenon (Dec 2006) 32. Anticytokine agents in rheumatoid arthritis (June 2007) 33. Recent advances in management of ankylosing spondylosis (June 2007) 34. Biologicals in inflammatory arthritidies (Dec 2007) 35. Metabolic bone disease (Dec 2007) 36. Reactive arthritis (June 2008) 37. Takayasu arteritis classification, clinical features and management (June 2008) 38. Scleroderma crisis (June 2008) 39. Sjogren's syndrome (Dec 2008) 40. Behcet's syndrome (Dec 2008) 41. Approach to ANCA interpretation (Dec 2008) 42. Enumerate the diagnostic criteria of systemic lupus erythematous. Describe the emergencoes in SLE (June 2009) 43. Enumerate various myasthania syndromes along with their differential diagnosis. How will you manage a patient of myasthenic crisis (Dec 2009) 44. Biological therapy in rheumatoid arthritis indications, contraindications and monitoring (June 2010)

HEMATOLOGY 1. 2. 3. 4. 5. 6. 7. 8. Diagnostic criteria and prognostic indicators in multiple myeloma (June 2000) Classification of eosinophilic disorders (June 2000) Complications of repeated blood transfusions (June 2000) Classification of myelodysplastic syndromes (June 2000) Immuno thrombocytopenic syndrome (June 2001) Adverse reaction to blood transfusion (June 2002) Theurapeutic options in aplastic anemia (Dec 2002) Discuss myelodysplastic syndrome with special reference to etiology, classification and management (June 2003) 9. Hypercoagulable states (Dec 2003) 10. TTP (Dec 2004) 11. Hypereosinophilic syndrome (Dec 2004) 12. Bone marrow transplantation in medicine (Dec 2004)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

13. Hypoproliferative anaemia causes , diagnosis, treatment (June 2005) 14. Causes, diagnosis and management of DIC (Dec 2005) 15. Sideroblastic anemia (Dec 2005) a. TTPC (Thrombotic thrombocytopenic purpuras) B. Indications and rationales of use of IVIg (June 2006) 16. Blood component therapy (June 2006) 17. Management of multiple myeloma (Dec 2006) 18. Recombinant factor VII (Dec 2006) 19. Medical management of aplastic anaemia (Dec 2006) 20. Idiopathic thrombocytopenic purpura (Dec 2006) 21. Management of ITP in adults (June 2007) 22. Reticulocyte Proliferation Index (June 2007) 23. Disseminated intravascular coagulation (June 2007, Dec 2007) 24. Immune mediated adverse drug reactions to blood transfusions (June 2007) 25. Sickle cell syndrome (June 2007) 26. Clinical features of sickle cell hemoglobinopathies (Dec 2007) 27. Blood component therapy (Dec 2007) 28. Thrombophilic state (June 2008) 29. Describe myelodysplastic syndrome. Outline classification, clinical features and diagnosis (June 2008) 30. Methaemoglobinemia; causes, clinical features and management (June 2008) 31. Refractory Idiopathic Thrombocytopenic purpura (Dec 08) 32. What is the WHO classification of acute myeloid leukaemia? How does it differ from FAB classification? Describe the prognostic features and line of managemnet for acute promyelocytic leukaemia (Dec 2009) 33. What is aplastic anaemia? Describe the clinical features and principle of management of aplastic anaemia (Dec 2009) 34. Etiological factors, pathophysiology, lab findings and treatment of disseminated intravascular coagulation (DIC) (June 2010) 35. Causes, diagnostic algorithm and management of a patient with thrombocytopenia (June 2010) 36. Clinical features, diagnostic evaluation and management of hemochromatosis (June 2010) DIABETES 1. Clinical features and diagnostic workup of diabetic nephropathy (June 2000) 2. Causes & diagnosis of spontaneous hypoglycemia (June 2001)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

3. Diabetic retinopathy (Dec 2001) 4. Pathogenesis of type 2 DM (Dec2001) 5. Postprandial hyperglycemia (June 2002) 6. Insulin sensitizers (June 2003) 7. Recurrent hypoglycemia (June 2003) 8. Discuss the challenges of DM in 21st century in India. (June 2003) 9. Glargine insulin (Dec 2003) 10. Diabetic cardiomyopathy (Dec 2003) 11. Preservation of beta cell functions in diabetes (Dec 2004) 12. Gestational diabetes mellitus (Dec 2004) 13. Mention possible etiologies of diabetic neuropathies (Dec 2004) 14. Diabetic neuropathy (Dec 2005) 15. Insulin resistance (Dec 2005) 16. Stress hyperglycemia (Dec 2005) 17. Diagnosis and principles of management of DKA (June 2006) 18. Newer insulin analogues (June 2006, Dec 2007) 19. Diabetic foot (June 2006) 20. Hyperosmolar nonketotic diabetic coma (Dec 2006) 21. Diabetic nephropathy (Dec 2006) 22. Gestational diabetes mellitus (June 2007) 23. Glycemic control and complications: trials in diabetes mellitus (June 2007) 24. GLP - 1 - Physiological role and therapeutics (Dec 08) 25. Classify glucose lowering therapies used in type 2 diabetes mellitus and their therapeutic use in regimens (Dec 08) 26. Dermatological manifestations of diabetes mellitus (June 2009) 27. Newer insulins (June 2009) 28. What are the diagnostic criteria for hypoglycaemia? Describe important causes, clinical manifestations and principles of management (Dec 2009) 29. Define incretin effect and discuss the incretin mimetics (June 2010) 30. Define gestational diabetes and outline its management (June 2010)

ENDOCRINOLOGY 1. 2. 3. 4. Osteoporosis prevention and management (Jan 2000, Dec 2007) Secondary hyperparathyroidism (Jan 2000) Hormone therapy in cancer (Jan 2000) Galactorrhoea amenorrhoea syndrome (Jan 2000)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

5. Discuss thyroid hormonogenesis and its regulation. Describe various thyroid function tests and their alterations in thyroid and nonthyroid disorders(June 2000) 6. Endocrine myopathies (June 2001) 7. Endocrine paraneoplastic syndrome (Dec 2002) 8. Sick euthyroid syndrome (Dec 2003) 9. Lab diagnosis of Cushings syndrome (Dec 2004) 10. Primary hyperaldosteronism (June 2005) 11. Throtoxic myopathy (Dec 2005) 12. Primary hypothyroidism (Dec 2005) 13. Evaluation of patient with suspected Cushings syndrome (June 2006) 14. Treatment of osteoporosis (June 2006) 15. Medical adrenalectomy (June 2006) 16. Myxoedema coma (Dec 2006, June 2007) 17. Paraneoplastic endocrine syndrome (June 2008) 18. Poly glandular autoimmune syndrome (June 2008) 19. Postmenopausal hormone therapy (Dec 2008) 20. Describe MELAS (Dec 2008) 21. Pseudohypoparathyroidism (Dec 2008) 22. Critical comment on the benefits and risks of post-menopausal hormone therapy (June 2009) 23. Management of adrenal crisis (June 2009) 24. Outline the management of thyroid storm (June 2009) 25. What are the benefits and risks of post-menopausal hormone therapy (Dec 2009) 26. Define paraneoplastic syndrome. Describe the causes and clinical manifeastations of this condition (Dec 2009) PSYCHIATRY 1. 2. 3. 4. 5. 6. 7. 8. Diagnosis and management of depression (June 2000) Sleep deprivation (June 2003) Panic disorders (Dec 2003) Anorexia nervosa (June 2005) Post traumatic stress disorder (June 2005) Management of delirium tremens (June 2005) Obsessive compulsive disorder (June 2006) Describe drug treatment of acute mania and bipolar disorders (Dec 2008)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

9. Discuss the conservative guidelines with respect to the drug treatment of acute mania and bipolar disorder (June 2009) 10. Discuss obsessive compulsive neurosis (June 2009) 11. Define dementia and delirium. Mention the causes of dementia and comment on the treatment of dementia (Dec 2009) 12. What is alcoholism? Describe the effects of alcohol on different organ systems and management of acute alcohol withdrawal (Dec 2009) 13. Describe the clinical features, diagnostic evaluation and treatment of bipolar disorder (Dec 2009) 14. Clinical features, diagnostic evaluation and treatment of depression (June 2010) SKIN 1. 2. 3. 4. Skin as a sign of internal malignancy (June 2000) Vitiligo (Dec 2003) Dermal leishmaniasis (Dec 2003) (A)Enlist the pathological entities involved in cutaneous T cell lymphoma. How will u confirm the diagnosis (B) Enumerate the skin changes in internal malignancy (Dec 2004) 5. Herpes zoster (June 2005) 6. Kaposis sarcoma (June 2005) 7. Pemphigus vulgaris (June 2005) 8. Paraneoplastic pemphigus (Dec 2008) 9. Define skin failure and enumerate its causes (Dec 2008, June 2009) 10. Toxic epidermal necrolysis - diagnosis and management (Dec 2008) 11. Discuss the cutaneous manifestations of systemic diseases (June 2009) 12. Discuss the etiopathogenesis of lichen planus (June 2009) 13. Describe the etiology, clinical features and principle of management of acne vulgaris (Dec 2009) 14. What is unstable psoriasis? Describe the clinical features, diagnostic evaluation and treatment of a patient of psoriasis (Dec 2009)

HIV & TUBERCULOSIS 1. Highly active antiretroviral therapy(Jan 2000) 2. Mode of mother to child transmission of HIV infection and its prevention (june 2000)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

3. HAART (June 2001) 4. Diagnosis, management of MDR TB (June 2001) 5. Fever in immunocompromised patient (June 2001) 6. MDRTB (Dec 2001) 7. Epidemiology of HIV(Dec 2001) 8. RNTCP merits and demerits (Dec 2002) 9. ART indications and preferred regimens (Dec 2002) 10. H A A R T (Highly active antiretroviral therapy): How to monitor its effectiveness (June 2003) 11. SARS (June 2003) 12. Opportunistic lung infection in persons with HIV (June 2003) 13. HIV vaccine current status (June 2003) 14. Diagnosis and management of pneumocystis carinii pneumonia in HIV positive patient (Dec 2003) 15. Perinatal transfusion of HIV. Current strategies (Dec 2004) 16. Define SIRS. pathophysiology and management (Dec 2005) 17. AIDS wasting syndrome (June 2007) 18. Immune Reconstitution Inflammatory Syndrome (June 2007) 19. HAART ( Dec 2007) 20. MDR-TB Diagnosis and principles of management (June 2008) 21. GI manifestations in HIV infection (June 2008) 22. HIV drug resistance and its prevention (Dec 2008) 23. Role of immunomodulators in MDR TB management (Dec 08) 24. Describe the management of health care personnel who has received a needle stick injury (June 2009) 25. HIV infections and the gut (June 2009) 26. What is the significance of CD4 T-cell count in a hiv positive patient? How to start anti-retroviral therapy? What is Immune Reconstitution Inflammatory Syndrome (Dec 2009) 27. MDR tuberculosis, diagnostic approach and drug management (June 2010) IMMUNOLOGY 1. 2. 3. 4. Assessment of autonomic dysfunction (JUNE 2000) Apoptosis (June 2000, June 2002, June 2003, June 2009) Immunomodulation & its clinical applications(Dec 2001) Antitumor necrosis factor antibody (June 2002)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

5. 6. 7. 8.

Natural killer cells (Dec 2006) Autoantibodies (Dec 2006) Poly glandular autoimmune syndrome (June 2008) Describe principles of passive immunisation and their clinical relevance (Dec 2008)

PHARMACOLOGY 1. Beta adrenergic blockers (June 2000) 2. Thalidomide. Newer indications (June 2001) 3. Refampin drug interactions (Dec 2001) 4. Clinical relevance of pharmacogenetics (June 2002) 5. Thalidomide current status (Dec 2003) 6. Monoclonal antibodies in clinical use (Dec 2004, Dec 2006, June 2009) 7. Low dose methotrexate therapy (Dec 2004) 8. Discuss briefly aspirin resistance (June 2005) 9. Therapeutic use of botulinium toxin (Dec 2007) 10. Drug interaction of rifampicin (Dec 2007) 11. Interferons: types, clinical uses and adverse effects (June 2008) 12. Describe cytochrome P450 and its relevance in clinical therapeutics (June 2008) 13. Antibiotic resistance (June 2008) 14. Interferons - types and utility in clinical medicine (Dec 2008) 15. Discuss the pharmacokinetics of drugs and the factors affecting the pharmacokinetics (Dec 2008) 16. Low molecular weight heparins : their basic and applied considerations (June 2009) 17. Liposomal drug delivery system (June 2009) 18. What is targeted therapy? What is the basic principle of such therapy? What are the presently targeted agents available and their uses? (Dec 2009) 19. Bioavailability of drugs and enumerate its clinical implications (June 2010)

ACIDOSIS AND ALKALOSIS 1. Compensation in chronic respiratory acidosis (June 2000) 2. Metabolic acidosis (Dec 2002) 3. Metabolic acidosis : diagnosis and approach (Dec 2007)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

4. Describe the Hasselbach equation. How is pH regulated in human body. Enumerate High Anion Gap disorders (Dec 2008) 5. Define anion gap. Enumerate causes of metabolic acidosis and mention algorithm for its management (June 2010)

FLUID & ELECTROLYTE IMBALANCE 1. Discuss calcium metabolism with special reference to hyper and hypocalcemic states (Dec 2002) 2. Clinical approach of hyponetremia (Dec 2002) 3. Syndrome of Inappropriate Anti Diuretic Hormone (SIADH) (June 2005, June 2007) 4. Fluid therapy in severely hypo volumic ill patients (June 2005) 5. Hyponatremia (June 2005) 6. Hypokalemic paralysis (Dec 2005) 7. Causes of hypocalcemia and management (Dec 2005) 8. Hyponatremia: diagnosis, etiology and management (June 2006, Dec 2007) 9. Hypercalcemia (Dec 2006) 10. Causes of malignancy induced hypercalcemia and its medical management (June 2008) 11. What are the cause of hypocalcemia? Outline the investigative approach and management of such case (June 2009) 12. Mention the causes of hyponatremia. Describe the clinical features and management of SIADH (Dec 2009) 13. Mention the causes of osteoporosis. How will you diagnose a case of Osteoporosis. What are the measures to prevent osteoporosis (Dec 2009)

GENETICS 1. 2. 3. 4. Human genome project (June 2001) Genetic counseling (Dec 2005, Dec 2006) Gene therapy (June 2007) Define chromosomal sex, gonadal sex and phenotypic sex. Describe the clinical features and treatment of a patient with Klinefelter Syndrome (Dec 2009) 5. Describe the relevance of cytogenetics in clinical medicine with examples (Dec 2009)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

SEPSIS AND CRITICAL CARE 1. 2. 3. 4. 5. 6. 7. Give an account of pathophysiology & management of septic shock (Dec 2001) Principle and techniques of CPR (June 2002) Physician contribution to infection control in hospital (Dec 2002) Hospital acquired pneumonia (June 2003) Noninvasive ventilation (Dec 2003) Interpretation of ABG (Dec 2004) Discuss briefly: a. treatment of septisemic shock; b. benign positional paroxysmal vertigo (June 2005) 8. Define shock. Management of different type of shocks (Dec 2005) 9. Immunonutrition in critical illness (Dec 2005) 10. Non invasive ventilation (Dec 2005) 11. Complications of mechanical ventilators (June 2006) 12. Systems of scoring to measure severity of illness in ICU and their utility (Dec 2007) 13. Hypothermia: causes, clinical features, treatment (Dec 2007) 14. Depict the normal flow volume curve and describe the various ventilatory functions and its clinical implications (Dec 2008) 15. Discuss in brief mechanical ventilatory support (June 2009) 16. What is septic shock? Describe its pathopysiology and priciple of management (Dec 2009) 17. Describe the non-invasive method of ventilatory support and the situations of its use. Describe the specific strategy of ventilatory management of a patient with COPD (Dec 2009) 18. Etiology, clinical features and treatment of malignant neuroleptic syndrome (June 2010) 19. Clinical features and management of cardiogenic shock (June 2010) 20. What is parenteral nutrition? What are its hazards and significance in relation to various disorders? (June 2010) 21. Define brain death and outline the means of ascertaining brain death (June 2010) 22. Fundamentals of palliative care (June 2010) 23. Mechanical ventilator its indications, advantages and complications (June 2010) 24. Define ventilator associated pneumonias. Enumerate the microbes causing it and outline the treatment approach (June 2010)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

ONCOLOGY 1. Oncogenes (June 2003) 2. Tumor lysis syndrome (Dec 2005, June 2006, June 2008) 3. Causes, clinical manifestation and diagnostic approach of superior vena cava obstruction (June 2010) 4. Enumerate tumor markers in relation to medicine and discuss their clinical applications and limitations (June 2010) PREGNANCY AND MEDICINE 1. Management of malaria in pregnancy (Dec 2008) 2. Write about the effect of pregnancy on valvular heart disease (June 2009)

PSM & BIOSTATISTICS 1. Positive predictive value of a diagnostic test (Jan 2000) 2. Quantitative mehods for clinical decision making (Dec 2002) 3. Randomised controlled trials (June 2005, June 2007) 4. Chi-square test (June 2005) 5. Descriptive and analytical epidemiology (Dec 2005) 6. Quantitative medical predictors of diagnostic tests (June 2006) 7. Case control study (June 2006) 8. Standard deviation (Dec 2006) 9. Meta analysis (June 2007) 10. Measures of accuracy of diagnostic tests (Dec 2007) 11. Biomedical waste management (Dec 2007) 12. What are the measures of disease probability and the role of Bayes' theorem in clinical studies (Dec 2008) 13. Management of biomedical waste (Dec 2008) 14. Null hypothesis (June 2009) 15. Define mean, median and standard deviation. What is the utility of Anova Test? Enumerate differnet types of research methodologies (Dec 2009) NUTRITION, ENVIRONMENT & METABOLIC SYNDROME 1. Total parenteral nutrition (Jan 2000) 2. Heat hyperpyrexia(Jan 2000) 3. Management of morbid obesity(Jan 2000)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

4. Hypertriglyceridemia (Dec 2001) 5. Chronic alcohol abuse(Dec 2001) 6. TPN (June 2002) 7. Describe pathogenesis, c/f, diagnosis, management of obesity (June 2002) 8. Hyperpyrexia (June 2003) 9. Pharmacotherapy in Dyslipidemia (June 2003) 10. Discuss the hazards of prolonged alcohol consumption (Dec 2003) 11. Noise pollution (Dec 2003) 12. Nutrional assessment (Dec 2003) 13. Assessment of obesity (Dec 2003) 14. Heat stroke (Dec 2004, Dec 2006) 15. Total parenteral nutrition (Dec 2004) 16. Drugs for dyslipidemia (Dec 2004) 17. High altitude diseases (Dec 2005) 18. Vitamin B1 (Dec 2005) 19. Postprandial dyslipidemia (Dec 2005) 20. Neutrogenomics (Dec 2006) 21. Pharmacological treatment of hyperlipidemia (June 2007) 22. Medical management of obesity (June 2008) 23. Principles of parenteral nutrition (June 2008) 24. CNS manifestations of alcohol (June 2008) 25. Elucidate the role of adipocyte in energy regulation. Define obesity and etiopathogenesis responsible for obesity (Dec 2008) 26. Quantification status of obesity (June 2009) 27. Define balanced diet. Enumerate various nutritional deficiency disorders and describe the clinical features and management of protein energy malnutrition (Dec 2009) 28. Classify dyslipidemias and approach to management of hypertriglyceridemias (June 2010)

POISONING 1. 2. 3. 4. 5. Diagnosis and management of aluminium phosphide poisoning(Jan 2000) C/F & management of OP Poisoning (June 2001) Aluminium phosphide poisoning (June 2002) Intermediate syndrome (June 2008) Describe acute and chronic manifestation of cocaine abuse (Dec 2008)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

6. Briefly discuss the principles of management of organophosphorus poisoning (June 2009) 7. Describe the clinical features and management of venomous snake bite (Dec 2009) 8. Describe the clinical features and management of lead poisoning (Dec 2009) 9. Clinical presentation of acute methyl alcohol poisoning and its management (June 2010) MISCELLANEOUS 1. Age related physiologic changes and their consequences (Dec 2003) 2. Unexplained visual loss (June 2005) 3. Polymerase chain reaction (June 2005) 4. Bioterrorism (Dec 2005) 5. Ethical issues in clinical research (Dec 2005) 6. A. Neuroparalytic snake envenomation B. Hyperbaric oxygen therapy (June 2006) 7. G6PD deficiency (June 2006) 8. Use of embryonic and somatic stem cell technology in medicine (June 2006) 9. Therapeutic angiogenesis (Dec 2006) 10. DNA vaccines (Dec 2006) 11. Stem cell therapy (Dec 2006) 12. CB1 receptor antagonists and their therapeutic role (June 2007) 13. Principle of clinical ethics (Dec 2007) 14. Immunization in adults (June 2008) 15. Recurrent falls in elderly causes and management (June 2008) 16. Bioterrorism: infective and chemical agents used for it (June 2008) 17. Describe the anatomy of the mediastinum. Discuss the common mediastinal masses and approach to the diagnosis (June 2008) 18. Current status of stem cell transplantation therapy in clinical medicine (Dec 08) 19. Acute radiation sickness and its management (Dec 2008) 20. Chronic Fatigue Syndrome (Dec 2008) 21. Bioterrorism (Dec 2008) 22. Stem cell therapy (June 2009) 23. What are the advantages of MRI as compared to CT? Enumerate the various contraindications of MRI (Dec 2009) 24. Write short notes on importance of extended spectrum beta lactum producing bacteria (Dec 2009) 25. Enumerate geriatric syndromes and outline the management of delirium. (June 2010)
Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)

DNB MEDICINE Q PAPERS (January 2000- June 2010)

26. What is evidence based medicine? Describe the various levels of evidence (June 2010) 27. Principles and applications of positron emission tomography (PET) in medicine (June 2010) 28. Pathogenesis, clinical manifestations and acute radiation sickness (June 2010)

Dr. Ganesh B. Dahiwal (Drdganeshb83@gmail.com)