PATHOPHYSIOLOGY

Non-modifiable Risk -Heredity -Race -Increasing age- 40 years & above -Gender- menopausal

Modifiable Risk -smoking -hypertension -increase serum cholesterol level -physical inactivity

Increase in the deposition of fat on blood vessel wall

atherosclerosis

Coronary artery

Stenosis of the arterial wall

CORONARY ARTERY DISEASE

blood swirls around the irregular surface of the plaque

Decrease blood flow to the heart

Platelet adheres to the plaque

Thrombus formation c/c: increase blood pressure Increase pressure on the walls of blood vessels HYPERTENSIVE CORONARY VASCULAR DISEASE

Increase peripheral vascular resistance Dislodge of plaque (emboli)

Diagnostic test: -ECG-changes in ST segment and T wave -Coronary angiography -CT scan -MRI

Passes into the circulation going to other blood vessels especially on the brain

Obstruction of blood vessels Decrease blood flow on the affected area

Decreased O2 supply and nutrients

BRAIN TISSUE INFARCTION C/C: extremity spasm

Diagnostic test: -CT scan -MRI

Tissue injury

triggers inflammatory response

Increase injury trigger inflammatory response

C/C: -episodes of vomiting -dizziness

Increase ICP