Name of Drug Classification and Indication and Contraindication Side Effects/ Nursing Responsibilities

Mode of Action Dosage Adverse Effects

Zosyn® Antibiotic Indicated for the History of Autonomic nervous • Advise patient or
(piperacillin Na and treatment of allergic reactions to system - caregiver that
tazobactam Na) patients with penicillins, hypotension, ileus, medication will be
Inhibits bacterial cell moderate to severe cephalosporins, or syncope
prepared by health
wall mucopeptide infectionscaused β-lactamase Body as a whole - care provider and
synthesis. by piperacillin- inhibitors; rigors, back pain,
administered in a
resistant hypersensitivity to malaise
health care setting.
piperacillin/tazobac any component of Cardiovascular -
tam-susceptible, β- the product. tachycardia, • Review dosing
lactamase including schedule and
supraventricular prescribed length of
producing strains
and ventricular; therapy with patient.
of microorganisms bradycardia;
in the following Advise patient that
arrhythmia
conditions: dose, dosing
Central nervous frequency, and
Bacterial infections system - tremor,
of the urinary tract duration of therapy are
convulsions,
vertigo dependent on site of
infection, severity of
Gastrointestinal -
infection, and response
melena, flatulence,
hemorrhage, to treatment.
gastritis, hiccough, • Advise patient or
Hearing and caregiver to
Vestibular System - immediately inform
tinnitus health care provider if
Hypersensitivity - injection-site pain or
anaphylaxis redness, skin rash,
Metabolic and hives, itching, or
 Nutritional - shortness of breath
symptomatic occur during
hypoglycemia, treatment.
thirst
• Advise patient or
caregiver to report the
following signs of
superinfection to
health care provider:
black “furry” tongue,
foul-smelling stools,
vaginal itching or
discharge, white
patches in mouth.
•Warn patient or
caregiver that diarrhea
containing blood or
pus may be a sign of a
serious
Name of Drug Classification and Indication and Contraindica Side Effects/ Adverse Nursing Responsibilities
Mode of Action Dosage tion Effects
TAZOCIN® Wyeth- Antibiotic/ß-lactamase Bacterial infections of Patients with Platelet, Bleeding, • Advise patient or
Ayerst Piperacillin Inhibitor the urinary tract a history of Clotting: mesenteric
caregiver that
Sodium--Tazobactam allergic embolism, purpura,
medication will be
Sodium reactions to epistaxis, pulmonary
prepared by health care
Piperacillin belongs to any of the embolism (see
provider and
the group of penicillins Precautions, General).
administered in a health
medicines known as and/or
care setting.
‘broad spectrum cephalospori Psychiatric: confusion,
penicillin antibiotics’. ns or b- hallucination, • Review dosing schedule
It can kill many kinds lactamase depression.
and prescribed length of
of bacteria. inhibitors.
therapy with patient.
Tazobactam can Reproduction, Female:
Advise patient that
prevent some leukorrhea, vaginitis.
dose, dosing frequency,
bacteria becoming
and duration of therapy
resistant to the Respiratory:
are dependent on site of
effects of piperacillin. pharyngitis, pulmonary
infection, severity of
This means that edema,
infection, and response
some bacteria, which bronchospasm,
to treatment.
are normally not coughing.
killed by piperacillin • Advise patient or
are killed when Skin and Appendages: caregiver to
piperacillin and genital pruritus, immediately inform
tazobactam are given diaphoresis. health care provider if
together. injection-site pain or
Special Senses: taste redness, skin rash,
perversion. hives, itching, or
shortness of breath
Urinary: retention, occur during treatment.
dysuria, oliguria, • Advise patient or
hematuria, caregiver to report the
incontinence. following signs of
superinfection to health
Vision: photophobia. care provider: black
“furry” tongue, foul-
smelling stools, vaginal
itching or discharge,
white patches in mouth.
 • Warn patient or
caregiver that diarrhea
containing blood or pus
may be a sign of a
serious disorder and, if
noted after discharge,
to seek medical care
and not treat at home.

Name of Drug Classification and Indication and Contraindicatio Side Effects/ Adverse Effects Nursing Responsibilities
Mode of Action Dosage n
Ciprofloxacin Antibiotic Used in Urinary Contraindicated CARDIOVASCULAR: palpitation, • Instruct that diarrhea
hydrochloride Tract Infections in patients hypertension, angina pectoris, is a common problem
caused by sensitive to myocardial infarction, caused by antibiotics
Inhibits bacterial Escherichia coli, fluoroquinolone CENTRAL NERVOUS SYSTEM: which usually ends
Cipro, Cipro I.V. , DNA synthesis, Klebsiella s. restlessness, dizziness, when the antibiotic is
Cipro XR, Ciproxin‡ mainly by blocking pneumoniae, lightheadedness, insomnia,
discontinued.
Use cautiously nightmares
DNA gyrase; Enterobacter • Stop taking
in patients with GASTROINTESTINAL: painful oral
bactericidal. cloacae, Serratia ciprofloxacin and call
CNS disorders, mucosa, oral candidiasis,
marcescens, dysphagia, intestinal perforation, your doctor at once if
such as severe
Proteus mirabilis, gastrointestinal bleeding, you have sudden
cerebral
Providencia cholestatic jaundice, hepatitis pain, swelling,
arteriosclerosis
rettgeri, HEMIC/LYMPHATIC: tenderness, stiffness,
or seizure
Morganella lymphadenopathy, petechia or movement
disorders, and
morganii, METABOLIC/NUTRITIONAL: problems in any of
in those at risk
 Citrobacter for seizures amylase increase, lipase increase your joints.
diversus,
MUSCULOSKELETAL: arthralgia • Advise patient to drink
Citrobacter or back pain, joint stiffness, plenty of fluids to
freundii, achiness, neck or chest pain, flare reduce risk of urine
Pseudomonas up of gout crystals.
aeruginosa, RENAL/UROGENITAL: interstitial • Advise patient not to
methicillin- nephritis, nephritis, renal failure, crush, split, or chew
susceptible polyuria, urinary retention,
the extended-release
Staphylococcus RESPIRATORY: dyspnea, tablets. Advise patient
epidermidis, epistaxis, that hypersensitivity
Staphylococcus reactions may occur
saprophyticus, or even after first dose.
Enterococcus If a rash or other
faecalis allergic reaction
occurs, tell him to
stop drug immediately
and notify prescriber.
• Tell patient that
tendon rupture can
occur with drug and to
notify prescriber if he
experiences pain or
inflammation.

Name of Drug Classification and Indication and Contraindication Side Effects/ Adverse Nursing
Mode of Action Dosage Effects Responsibilities
DIAMICRON® (anti-diabetic drug) Control of Use with caution in Disturbances of the gut • Take exactly as
[GLICLAZIDE hyperglycemia in such as diarrhea, directed; with
 gliclazide responsive constipation, indigestion, meal(s) at the
• Elderly people.
diabetes mellitus of nausea, vomiting or same time each
stable • Decreased kidney abdominal pain. day.
Gliclazide works function. Temporary visual • Do not change
mainly by stimulating dose or
• Decreased liver disturbances at start of
the cells in the treatment. discontinue
pancreas that function. without
produce insulin. Low blood glucose level consulting
These cells are called (hypoglycaemia). prescriber.
beta cells. Gliclazide • Avoid alcohol
Skin reactions such as
causes the beta cells while taking
rash and itch.
to produce more this medication;
insulin. Disturbances in the could cause
normal levels of blood cells severe reaction.
in the blood.
• Inform
Yellowing of the skin prescriber of all
and eyes (jaundice). other
prescription or
Disturbance in liver
OTC
function.
medications
Inflammation of the you are taking
liver (hepatitis). • do not
introduce new
medication
without
consulting
prescriber
• Do not take
 other
medication
within 2 hours
of this
medication
unless advised
by prescriber
• If you
experience
hypoglycemic
reaction,
contact
prescriber
immediately.
• Maintain
regular dietary
intake and
exercise routine
and always
carry quick
source of sugar
with you.

Name of Drug Classification and Mode Indication and Contraindication Side Effects/ Adverse Nursing
of Action Dosage Effects Responsibilities
Generic Name: Classification: Acetaminophen is Contraindicated in neutropenia, - ask patients SO if
used to treat many patients leucopenia, jaundice, patient has a history
Paracetamol Nonopoid analgesics
conditions such as hypersensitive to the rash, urticaria of hypersensitivity to
and antipyretics
 headache, muscle drug Hemolytic anemia, the drug
aches, arthritis,
Brand Name: Action: - monitor for
backache,
development of
Tempra Unknown. toothaches, colds,
hypersensitivity
Thought to produce and fevers.
reactions: rash,
analagesia by blocking
urticaria, sorethroat
pain impulses by
inhibiting synthesis of - tell patient to report
prostaglandin in the adverse reactions
CNS or of other promptly
substances that
- advise patient that
sensitize pain receptors
drug is only for short
to stimulation. The
term use
drug may relieve fever
through central action - warn patient that
in the hypothalamic high dosage,
heat regulating center longterm unsuper-
vised use of drug can
cause liver damge