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DR UGS DR UGS
Drugs and health
Drugs are chemical substances that are taken for a specific effect. In the case of illegal drugs (also known as recreational drugs), such as marijuana, cocaine, heroin or ecstasy, the effect is to alter the functioning of the brain to provide sensations that are experienced as pleasurable. All drugs have desirable and undesirable effects. One of the undesirable effects of recreational drugs is a continued compulsion to use the drug, even when its use creates problems in finances, relationships, health (both physical and mental), school and/or work. Although avoiding drug use has been linked to better overall health and well-being, some people choose to use recreational drugs. It is important for those who do use drugs to be informed about them, to be able to identify the potential problems that they can cause, to identify when their use has become problematic, and to use them in such a way that eliminates or reduces the risk of problems associated with their use.
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difficult to do other things such as run a machine, play sports, or even write an exam. The greater the amount used, the greater the risk of having a problem. Medicine taken in the amount directed by a doctor may be helpful. Too much of the same drug may be harmful or even cause death. Likewise, as the amount of any of the illegal drugs taken increases, so does the chance of harm. The more often a drug is used, the greater the risk of having a problem. For instance, studies indicate that those who use marijuana regularly are at higher risk of experiencing problems associated with marijuana, such as difficulty processing complex information. Risk increases with the length of time a drug is used. There are risks involved with using more than one drug at a time. For example, drinking alcohol while using a legal or illegal drug may produce dangerous effects. This is because the combined effects of such drugs may be greater than expected. The person using the drug makes a big difference. People using drugs can be happy or depressed, cautious or careless, healthy or mentally/physically ill. They may react to a drug in the way that most other users of that drug react, or they may have an unusual reaction. Some may be more likely to become dependent. All of these things will affect what happens when someone uses a drug. It is often impossible to know what effect a drug will have on a person before he or she begins to use it. A persons physical or mental health and his or her reasons for using the drug must be considered.
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Misusers become preoccupied with the drug and think frequently about when they will use again. Parties, and other social events, are often chosen for whether or not the drug of choice will be present. There is some level of discomfort if the drug is not available, and another drug, often alcohol, may be substituted. Other indicators of misuse include: High levels of conflict with close friends Family or friends are concerned about the persons use of drugs Patterns of isolation, including breaking relationships with those who do not use Irritability, restlessness or discontentment Unpredictable mood swings Legal problems Financial problems, including growing debt Job- or school-related problems, including chronic absenteeism or lateness People living a pattern of drug misuse can also have significant health problems. Many misused substances are highly toxic, leading to weight loss, hair and tooth loss, acne, lesions or life-threatening liver problems. General levels of stress tend to be very high, creating additional problems of their own. In the fourth stage, the "chemically dependent" or "addicted" person continues to use substances despite continued consequences. Almost always preoccupied with the next smoke, or fix, these people spend a significant amount of their time, money and energy avoiding the emotional and physical discomfort of not using. Addicts usually do not see that the consequences they're experiencing are a result of the misuse; rather, they feel that their life is such that they need drugs to cope with life's problems. ("You'd smoke too, if you had my level of stress/ had my job" etc.) They have an overwhelming desire to re-create the physical sensations and emotions that the drug provides. The combination of physiological craving and psychological need is one of the hallmarks of addiction. Ironically, chemically dependent people commonly see themselves only as regular users. Then, when they misuse and experience some consequences, they attempt to control their intake for a time. Then they misuse again. This back and forth pattern is a common symptom of the last stage. All the while, each symptom found in misusers becomes more serious. It is very important to note that people can't stay in addiction without significant assistance from the people around them. In case after case, chemically dependent people have relied on the financial and emotional support of family members, patience of friends or employers, even handouts on the street to continue their addictions. Ultimately, well-meaning people can actually keep the addict from the "precipitating crisis" such as threat of arrest or jail, failing school, separation or divorce, loss of yet another job or other financial distressthat makes them willing to make real changes.
Marijuana
Marijuana is the name given to a plant whose leaves are consumed, usually by smoking, to provide pleasurable effects. The plant belongs to the genus Cannabis and the active substance that produces the desired effects is known as THC (chemically it is called (-)3,4-trans-delta-ttetrahydrocannabinal). The leaves of the cannabis plant can be processed to form hashish (hash) and hash oil, both of which have higher concentrations of THC than the leaves. Attitudes towards cannabis use are changing. In the 1980's, a majority of people opposed its decriminalization. However, in the 1990's an increasing number of people adopted more liberal attitudes to the extent that a majority of Canadians currently support decriminalization. The main reason for this shift has been attributed to the increased awareness of the beneficial uses of cannabis, often referred to as its "medicinal" effects. The Canadian government has responded by establishing a task INTERESTING force, which is currently overseeing the cultivation of research grade cannabis as well as coordinating trials INFO to examine its effects on health. Interestingly, if cannabis did not have medicinal uses, surveys show that a majority of people would oppose its decriminalization. Marijuana is the most The majority of people that use marijuana do so for its pleasurable, rather than its medicinal, effects. used "recreational" drug Marijuana can have an impact on health in a variety of ways. In 1997, the World Health Organization in Canada. Surveys gathered a group of experts to review thousands of scientific reports on cannabis to determine how it affects indicate that health. What follows is a summary of the information that was published in the document titled "Cannabis: approximately 7% of A health perspective and research agenda." Canadians, 15 years of age and over, have used marijuana in the Acute effects of cannabis last year. A survey of The acute effects of cannabis are those that occur just after using it. Everyone responds to cannabis in Concordia students their own unique fashion. The following are commonly reported acute effects of marijuana: revealed that 29% of mild euphoria students had used relaxation marijuana in the last increased sociability year (9% had used it in heightened sensory perception the last month), and increased consumption of high carbohydrate foods that 56% of students loss of sense of time had never used the perceptual changes drug. depersonalization (feelings of loss of personal identity or feelings of being different, strange or unreal)
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Some people experience unpleasant effects with marijuana. These unpleasant effects are more common at higher doses or in naive users. They include: sensation of high anxiety tension confusion panic Marijuana appears to impair all cognitive processes associated with learning, with the exception of abstract thinking and vocabulary. People under the influence of cannabis do more poorly on learning and remembering tasks than people who are not under the influence. Marijuana also impairs psychomotor performance, such as handwriting, and hand-eye motor coordination, which are needed to drive a car. For this reason, people should never drive or operate heavy machinery under the influence of cannabis. Research supports that there is an increased risk of a motor vehicle accidents in those who are intoxicated with cannabis.
Ecstasy
Ecstasy, also known by other names including Adam, E, XTC, "Euphoria" and "Love Dove" is a relatively new drug. It was first synthesized in Germany in 1914 for use as an appetite suppressant and was used briefly by psychotherapists in the United States to aid patients in "opening up". Because the drug was found to have no therapeutic effect it was never licensed in Canada. Since no pharmaceutical companies produce it, ecstasy is often made in clandestine laboratories, often in someone's home. Scientists call ecstasy methylenedioxymethamphetamine (MDMA) and it is categorized as a hallucinogenic amphetamine because it is related to amphetamine and mescaline (a hallucinogen). It is usually taken as a tablet, but it can also be injected, snorted or inserted as a suppository. It is a drug that is most commonly associated with raves (all night dance parties). Ecstasy is believed to work by altering levels of chemical neurotransmitters in the brain. More specifically it appears to increase levels of
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dopamine, norephinephrine (which regulates alertness and heart rate), and serotonin (which regulates emotion, pain, appetite, sexual function, sleep and circadian rhythm among others). Although individuals vary in their reaction to taking the drug, for most people the benefit is a pleasurable change in mood and a perception of feeling more connected to others. Users report feeling empathetic, sensual, energetic, hyperactive and overly talkative. Effects occur about 45 minutes to an hour after taking the drug by mouth and they can last for up to 6 hours. Because of these pleasurable effects, there is a potential for abuse to attain these psychological benefits. The drug is not considered to be physically addictive. Along with the pleasurable effects, a long list of other effects can occur with ecstasy use that are much less pleasurable and some are potentially dangerous. The most common of these are an increase in heart rate, blood pressure and muscle tension, which often manifests itself as involuntary teeth clenching. Other side effects include: nausea, blurred vision, rapid eye movement, faintness, chills, sweating, tremors, dry mouth and throat, and nervousness. Mental and emotional instability, anxiety, delusions, paranoia and depression have been reported to occur after the pleasurable effects of the drug have worn off. These after effects are often related to taking larger doses of the drug. There is evidence that people who develop a rash that looks like acne after using ecstasy may be risking severe side effects, including liver damage, if they continue to use it. Use of ecstasy has been linked to deaths. The drug increases body temperature and depresses the desire to eat, drink and sleep. Deaths have resulted from hyperthermia (dangerously high body temperature) and kidney failure. In May of 2000, 2 men died in Toronto after taking a street drug disguised as ecstasy. As with other drugs, buyers can never be sure of drug quality and purity. It is advised not to mix ecstasy and alcohol, because alcohol also dehydrates and depresses some of the bodys processes. Ecstasy should also not be used with other stimulants or by people taking antidepressants that inhibit MAO (monoamine oxidase). People with heart ailments, glaucoma, hypertension, a history of aneurism or "stroke", liver or kidney disorders, diabetes or hypoglycemia should not take ecstasy. Information on a variety of Besides deaths, experts that study the effects of ecstasy are also alarmed about the physical changes drugs that can occur in the brain after using the drug. There is scientific evidence from the laboratory and from animal studies to indicate that ecstasy damages nerve cells in the brain. It appears that the drug actively www.nida.nih.gov/ dumps serotonin, and in doing so the part of the brain nerve cells that produce and release serotonin may Infofax/ be destroyed. Since serotonin is involved in the regulation of mood, experts fear that mood disorders may show up in years to come in those who have used ecstasy regularly. Frequent or regular users would be Infofaxindex.html most at risk for these psychiatric problems. A "natural" variety of ecstasy called "herbal ecstasy has surfaced and experts warn that it is not safer than ecstasy. It contains amphetamine and an herbal stimulant called "ma huang" which has also been linked to fatal consequences. As with any recreational drug, deciding to use ecstasy should involve carefully evaluating the potential consequences along with the potential benefits. Should you decide to use ecstasy you should take steps to avoid the main dangerous side effect, which is dehydration. Drink water even if you don't feel thirsty, but don't drink too much. Half a litre an hour is a good amount. Drinking juices and soft drinks is also helpful. Dress lightly and take rest breaks from dancing.
ON THE NET
Club drugs
Club drugs are drugs that are popular, and often easily available, at all-night dance parties known as raves, as well as at clubs and other dance parties. Club drugs include ecstasy, cocaine, GHB, ketamine and nitrous oxide Some information on several of these drugs has been presented throughout this chapter. Below is information on ketamine and nitrous oxide.
Ketamine
Ketamine hydrochloride ("Special K" or "K") was originally created for use as a human anaesthetic, and is still used as a general anaesthetic for children, persons of poor health, and in veterinary medicine. Ketamine belongs to a class of drugs called "dissociative anaesthetics, which separate perception from sensation. Other drugs in this category include PCP and nitrous oxide (laughing gas). Ketamine usually comes as a liquid in small pharmaceutical bottles, and is most often cooked into a white powder for snorting. At lower doses ketamine creates a mild, dreamy state. Users report feeling floaty and slightly outside their body. Numbness in the extremities is also common. Higher doses produce a hallucinogenic (trippy) effect. This experience is often referred to as entering a "K-hole" and has been compared to a near death experience with sensations of rising above one's body. Many users find the experience spiritually significant, while others find it frightening. While in a K-hole it is very difficult to move. People usually remain seated or lying down during the experience. While low doses of ketamine can increase heart-rate, at higher doses it depresses consciousness and breathing and is extremely dangerous to combine with other drugs with depressant effects such as alcohol, Valium or GHB. Frequent use can cause disruptions in consciousness and lead to neuroses or other mental disorders. Ketamine can cause a tremendous psychological dependence. The dissociation from one's consciousness experienced with ketamine can be highly seductive to some people, and there are many cases of ketamine addiction.
Nitrous oxide
Nitrous oxide (laughing gas) is a gas that has been safely used as a mild anaesthetic in combination with oxygen for over a century. It is classified as a "dissociative anaesthetic." Nitrous oxide is always inhaled. Users either inhale the gas directly from a tank or else dispense it first into balloons.
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DRUG
&
STREET NAMES
EFFECTS
DANGERS
Increased alertness, blood pressure, and Short-term: anxiety, paranoia, jitteriness heart rate and severe behavioral changes Appetite loss Long-term: potential permanent mental In large doses: sleep deprivation, and mood disturbances, malnutrition, severe agitation, aggression and paranoid anxiety delusion Increases activity of brain neurotransmitters Euphoria, increased alertness, racing thoughts and speech, loss of appetite Eventual anxiety and paranoia Highly addictive Long-term: paranoia, depression, irritability, internal organ damage, high blood pressure, irregular heartbeat, potential heart attack Very addictive Any heroin sold on the street may be adulterated with toxic chemicals or can cause a deadly overdose Long-term: liver damage Blood borne diseases (such as HIV/AIDS) if uncleaned needles are shared Extremely habit forming Because they decrease the brain's sensitivity to the need for oxygen, overdose can cause the user to stop breathing Can easily cause nervous system, brain, heart, liver or kidney damage Disorientation, violent behavior, unconsciousness and even death have occurred after a single use May cause mood or thought disturbances Inexperienced users may behave dangerously, and 'bad trips' of uncontrollable negative thoughts or emotions can result in long-term psychological harm Effects are similar to psychosis, and people often behave violently or suicidally Because it blocks pain receptors, users may harm themselves without knowing it Users can become dependent and longterm use can result in speech, memory or thought disturbances Dosages are unpredictable because the amount of chemical in mushrooms varies All psychedelics may cause mood disturbances with long-term use Inexperienced gatherers may not be able to distinguish between "magic mushrooms" and poisonous varieties
Sense of pleasure and euphoria Heroin (see below for other Withdrawal brings, tremors, sweating, anxiety and strong cravings opiates)
Reduce pain, cause sedation, and produce strong feelings of euphoria and well-being that diminish with use Possible nausea, constipation, and cough suppression
Changes in consciousness and visual perception Inhalants Sometimes nausea, vomiting, headache (poppers, snappers, and increased blood pressure bolt, bullets) Short-term: euphoria, lightheadeness, confusion, dizziness, fatigue, and hallucinations Sensory distortions, sense of slowed or quickened time, hallucinations Sometimes feeling out of control or even a psychotic state that lasts several hours When smoked, swallowed or snorted, interrupts brain function and provides sense of disconnection from reality with euphoria, confused thinking and sometimes hallucinations Can cause difficulty moving or talking, confusion, agitation and paranoia Effects can be felt as long as 24 hours to 2 weeks after use Changes in consciousness and visual perception Sometimes feeling of anxiety, "spaciness" and loss of control Can cause nausea, vomiting, headaches and increased blood pressure
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A lungful of nitrous oxide results in the temporary loss of motor control and a "dissociative" psychological effect, where sensations and perceptions become disconnected. Users report a dreamy mental state, and may experience mild auditory and visual hallucinations. The effects come on immediately and usually last less than a minute. Repeated inhalations of nitrous oxide can extend and intensify the experience. Since nitrous oxide produces an immediate loss of motor control. There have been many injuries and a few deaths from people who have fallen down after inhaling it. Your brain needs oxygen! Brain damage and suffocation can result from inhaling pure nitrous oxide for an extended period of time. Nitrous oxide can be extremely cold when it comes out of the tank. Cold gas can burn the skin as well as the lips and throat. High pressure levels in the tank can shoot the gas out at a dangerously fast speed and damage the lungs. This is why the gas is often dispensed into a balloon and allowed to warm up before being inhaled. Nitrous oxide can be psychologically addictive. Although rare, some people have become addicted to nitrous oxide and other dissociatives. The regular use of nitrous oxide can cause long-lasting numbness in the extremities and other neurological problems.
Gammahydroxybuyrate (GHB)
Gammahydroxybuyrate (GHB) is a drug that can be synthesized by kitchen chemists. It acts as a central nervous system depressant, meaning that it slows down some of the bodys processes that are controlled by the brain. Some people take this drug to enhance their experience with alcohol (another central nervous system depressant) but this is a dangerous combination. At low doses, the effects of GHB are similar to that of alcohol, making the user feel happy, sociable and relaxed. Higher doses can bring on unwanted effects such as dizziness, vomiting, muscle spasms and loss of consciousness. GHB can cause amnesia, where a person does not remember what happened after taking the drug. The difference between the amount needed for intoxication and that needed for adverse effects is small. Because GHB slows down body processes, high doses of the drug can lead to respiratory depression and eventually coma. GHB has caused a number of deaths. GHB usually comes as a clear, odourless liquid, making it easy to slip into a persons drink. It has also been produced as a white crystalline powder.
Rohypnol
Rohypnol is classified as a sedative/hypnotic drug, so it causes drowsiness, confusion and a general reduced level of consciousness. Other effects of rohypnol include impaired judgement, impaired motor skills and disinhibition...basically the same effects as alcohol. As with GHB, it is dangerous to mix rohypnol with alcohol, because each drug increases the effect of the other, including negative effects. The effects of rohypnol occur within 20-30 minutes of taking it. Rohypnol can cause deep sedation, respiratory distress, blackouts that can last up to 24 hours, and amnesia, where users forget events experienced while under the influence. In some cases, the drug has paradoxical effects and causes users to become aggressive. The potential for overdose or death can occur, especially when mixed with other drugs like alcohol. Besides being used as a predatory drug, rohypnol has also become popular as a club drug.
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