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2006

1 202


168 115
117


20
40
7 6

2 202


23%

3 202

4 202

5 202

<<>>

6 202

300
44 29

7 202

628

23

??

8 202


21

placenta


hepatitis B virus


8
3 28

9 202


masked civet SARS
SARS
29 9000 800
400
1997 viruses
of Bird flu


cardiovascular disease,

hepatitis A1988
4
16 1

ark shell 40
30
1988

200

10 202



19691976
4 5
450
80 lead
poisoning;plumbism;saturnism]

lead oxide]

5
1000

11 202

21
80%

3.2

9.11

2004 2004
sexual precocity]


30

20 14
10 8

12 202

hormone

ciprofloxacin]

2
2

chloromycetin;
chloramphenicol]


5 15

13 202

300

clenbuterol
residue of pesticide
sodium formaldehyde
sulfoxylate formaldehyde


1940

2003 (SARS)

2004

50

intestinal carcinoma cervical

14 202

carcinomaovarian carcinoma

40 50

50
50% 8000 1000

100%

2003

50

15 202




clenbuterol 2

beta-adrenergic receptor
agonist]

16 202

2004 7


484 200

2004 5 20

2001 5 15 24

2003 4 21 2
2002
7 2
80 20
25%

17 202

2006 9

189 60
9 336
1998 18 1700
1
50
60


2004

20052006

12005 1 28
108 31 67

10

22005 3 5 :

2003 7 7 272 6528

18 202

32005 3 14

42005 3 16

52005 3 24 52

62005 5 25

3
72005 6 5

82005 6 16

92005 7 19

448 1980
--
102005 9 6
2005-07-28 430
11 6 24

19 202

8 21
70
129 13
9 16 300
13 11 12

14 11 17 30
30

15
1



2004
2003 652.5 277
21
65.5 46

1958

20 202



600
600 4000

2003 1128

GDP 2000
2005 3

90 350 3000
2000
5000 21
30

21 202

2006

22 202

12 15
18
86

11
12

1996 6 157 36
1996 6 27 7 21
192 35 6
1997 6 7
255 73
1998 2
200 7
1998 200
3
1999 1 46 6
34
23 202

1999 51
1999 8 700
2001 5000 10
2001 20 2
2001 11 1 11 7 484
2001 9 4 6000
2002 100 5

2002 3000
2002 5 37 8-14
1605
2002 6 13 78

2002 7 8 40
2003 2
2003 3 19 3000 3
2003 4 SARS

2003 6 6
87
2003 7 3 76
9
4-

2003 7 28 B1 3
300
2004 2 21 448 15
9 40 9 10 403
3 2 5 2
9 399 1
24 202

2004 4 100 10

2004 9

2 2


40

2001

2001 11 90

2002 1
25 202

180

23% 20 80
80%

400

300

30
1520

26 202

2-90

275%

1999 4

2002 7 2 80

2001 11 7
484
2001 8 26 530
27 202

300 230
2001 11 17
14

2003 10 21 62

2004 3 14

2040
2004 7 5 82%
90%

31


28 202

50

29 202

2006 12 18

,,

Gro.Harlem brundtland,

50

2001

30 202

2001

RISTIC


2001 11 90

2006 11

Enrofloxacin

Ciprofloxacin

31 202

11 24
15
11 3/4
0.00222.3
12 2
10 ( ) 3

12 14
12
3
,
,

32 202

10%

100 22 3-MCPD
3-MCPD

1
1 8


1840

33 202





10

34 202

1 53

35 202

36 202

2002 1 28
1 31

6.23
95 300-500 4.96

2002 1 FDA
5 24

2002 3 11


2002 5 33.5%
5 12%

37 202

2002 2 6 FSA
7

,
Malachite green.
, .,
,,
, ,
, ,

,
,,,


flavomycin

potassium permanganate

38 202


0.04 ppm
DDT DDT

2002 3 6

7.3
480

2.1

1
2002 1
100%3 20 18
7
180

39 202

2002 1 31

1999 8 2000 1 6
634

40 202

2004 5 6

22

MARC RICHARD

300

2004 6 21


133
6 19

sorbic acid

benzoic acid
aflatoxin
2004 5.1

1-5 5.1

41 202

2003 5.9

370
,,2002 3 ,
, mad cow disease,
7 30 ,,
2002 4 21 ,,

2004 10 90

2005 8 1 thiodan
30mg/kg 0.01mg/kg

12
2005 8 403.9
78.2 36.2% 43.1%
4

90

2004 4 23

42 202

4.4 70%

FDA FAO
8 1 FDA 634

20 1000


1990

43 202

44 202


knownsin
J.R.1947

2001 8
22
2001 1 27

20

45 202

?
257


70 Lyme
disease foot and mouth disease

70

46 202

? 1965

50%

Protein aceous
infection particle, prion
MBM

vCJD
100%

1980

47 202

FAO2001 4240
46.1%

''

48 202




?moy senerh uniuessily,
? ?
febrauy sevunlh univenrity

1990

1980

30

49 202

1980


800 1000
100

1980

2003 1-5
1.78 62.23%

1980
88.8%1985
1990
1988 1998 10

50 202

1960 0.95
0.84 , 0.75 1980
11

0.8 10
8

1600 2500


0.1 20

10-20 8 22
275%
10%
20% 50%
100% 300%

25

51 202

1980


1990 3 135 43

52 202

1990 3 1990
7 125 1992 1 1994
359 232 97%
1995 16 22


1996


1.5

53 202

50

4 4

4
11 20


1998 5 1
17

1998

25 102
6 30
9
58

54 202

1999 4

2000 1 12
1 19 3 10 6

20

2001 8
50

2001 8
9

500
3 12 9
10
630

2001 8 26 530

3
530 300 230 51

55 202

2001 11 17 11 2
14

86
25%

2001 11 7
484

11 8
11 9

11 10

2002 3 25 3 14 10
3
13

14 3 14 15

56 202

26
24
4

5
2002 4 4 4
35
31

2003 10 21 62

18
2004 3 14

2004 4 3

70

57 202

2002 11 21

2002 1
100 30
20
4 6
20 2002 135
20
14

5 3000

2
6000
8
50 50

22 2003 2 11
5
1
2002 8 23 15
25

58 202

9 1

9 9
22
2001 80

80
23443.50

2003 1
2002 6 3

55
60


2002
2002
83235
2003 116
3643

59 202

1997 3
1998 98]2

1999
1999]1

1999 5 29

2000 4 3
2000]4

2001

2001 6
2001]14

2002
193

2004 3 17
60 202

8
2004]66

61 202



2003 8

2003 9

500
2004 1 24
QS
QS
2004 4 12

2004 7 2

dimethoate

62 202

63 202

2000 100
150 100
45

20%

2002 19 3.3
15.6%

64 202

,,
.

15

35

65 202


2008

66 202

50000

GMP

2006

67 202

1990


2002 6


2004
948

68 202

??

13


69 202

1899


?

70 202

??

21

----

dichlorvos

71 202

50


99%

2004 6 16

56 70 16 22.86%
17 9 48


215 2004 6 16 215

2642
215
3.2
1.7 215

72 202

36

30

,
11

ameba

4
biang

73 202


2004 6 18 54

17

14

5
,

2004 6 11
5
1.8
4

borax]

74 202

2003 7 1


5
2000

4%
70% 80%

27.8 // 400
91200 / 490
78
80

75 202

21

2004 7 5 82%
90%

76 202

31


50% 4

1
2001 10
2040

organophosphorous pesticide
nitrite]

2
2004 6 6

16 10
41 17 9

7
90 33 hydrogen

77 202

peroxide sodium hydroxide magnesium


sulfate ammonium sulfate 15

3
2004 7 2004 3 13
7 sulfur dioxide 200
24.5 ,---
24.5 24.5


---
sodium pyrosulfite

30% 1992

1992

100 5-6
8 1 25 1

78 202

403 2

168 115
117
3 2

54.8

110
160
12 3
1800
400
1100 700

79 202

0.2 0.5
3

10% 20%

1.82 1 18 35
600 139 6360 118
170 1.82 25
203
1999 2004 7 203

8 1
6
92

20
1000 4

500

2
500 250
1125
2.4 1.6 10
7

80 202


21305924664968853184

15
5
2004 6 11
Listeria
monocytogene
87.1%
43 7 21
7 13
55 1

tetradotoxin; balloonfish-toxin

chlorinated pesticide
15

5
2004 6 8 12
15
28 18
16 5 6
5 19
5 17 18
47
7 18
9

81 202


73

potassium sorbate
carmine
dye

lemon yellow
saccharin
Sodium Cyclamate

82 202

6 1


13

10
2004 4


methamidophos 1605

83 202

75%
54.5%
66.7%
77.8%8 6
29 30 18
60%

543 (

)
113 65 57.5%

60
80

25 1300
. 5 7
4 11 4

2004 4

84 202

2003 7

5 18

2004 7 9
4

120
1440 60
7 16

7 27 20

7
88.7%
acid value
64.0%

85 202

63.6%


6?22

6?22
staphylococcus aureus

6?22 5 1000
12
52% 18%

7 24

1230

86 202

7 4

46
48 1
78

400

300

87 202

30

24

100
50

88 202

,, :
. ,
, 1960
,,,
,
13
2003
2003 4 10
2003 8 7
13 130

33 45

89 202


4 23 10

140

189
189 148
5 5 148 9

148

4 189

8 8 4 23

90 202

2004 4 24

890

4 25
4 26
6 4

4
5

91 202


10


2.13% 4 25

4 25 4 27

5 2
4700


8 6

6 23

2001 8

92 202

25
15 5

50

2000

93 202

1987 12 1988 2 30

1996 6 157 36

1996 6 27 7 21
192 35 6
1997 6 7
255 73
1998 2
200 7
1998 200
3
1999 1 46 6
34
1999 51

1999 8 700

2001 5000 10
2001 20 2
2001 11 1 11 7 484
2001 9 4 6000
2002 100
94 202

5
2002 3000
2002 5 37 8-14
1605

2002 6 13 78

2002 7 8 40
2003 2
2003 3 19 3000 3
2003 4 SARS

2003 6 6
87
2003 7 3
76 9
4-
4- methylimidazole
2003 7 28 B1 3
300
2004 2 21 448 14
9 40 9 10
403 3 2 5 2
9 399 1
2004 4 100 10

2004 5
8
24 65.8%
5
95 202

65
21

29 7
4

10 3

32 26

2006 11 9

96 202

2006 11 26

30%

2006 11 26
4

1999 5

97 202

25

1996 3
30 400
30
1015
--
33

1997

60% PCBs

5
68%
PCBs

98 202

2003

2002 10
20 20 2740
295000

1 60 2004 4 19
?
5 5 ?
5
?
30

98 ? 30

?
1.2.
3.
3

99 202

1 9
84

11 ?

100 4600
2300 2300

2004 6 23

20

32 31

2002 5 10

Ali Adbo

100 202

1996

1997
FDA
FORC-G

2003 2 3


FDA

60%

101 202

6000

500

100

102 202

40%

1985
2000
400
200


1987 24
2000

Chlorofluorocarbons] 10 1990 60
2000
103 202

1992 11 86

2000 1996



21

2004 7 21

104 202


2004 4

2004 4 29

2004 5 21

2003 11 19


2001



2004 7 3

105 202

2003 2002
10

8
27 1
2004 3

1984

30

106 202

2004 3

2002 8 1
10

107 202


2001 2003 70% 10

104
45 291
176 75 2439

108 202

:2005 04 13 16:08
2004


2004 3 11

1990 1994
16

10

109 202

7 7

ethephon

minamata disease
2000 50

(DHHS)
FDA USDA FSIS

DHHSEPA

CDC(NIH)(ARS)

110 202

FSIS FDA FSIS

FDA EPA

APHIS
FDAAPHISFSISEPA

300%

2004 3 8 1983 7 16

111 202

7 50
100


8 3 5 67

113.013
2 10
344
10
6

6 15
13

112 202

2006 10

120 4

74

60
40

113 202

10.6%
9
3

6 2004 8 4 10
40 40 29 72.5%
**

**
6

8 7
8 22 109

114 202

1980
20

20

20

115 202


1985

2000

50


116 202

2005 5
2005


300

40

2005

117 202

1981

20%

118 202

10
1.

2.
3.

4.
5.
119 202

6.
7.

8.
9. 2

10.


120 202

(1)

10%

10 13
1014

121 202

122 202

18

(1)
123 202

(2)

(3)

4
5

124 202

(1)

(2)

? ?(
)

(3) ? ?

2
3

4 15%

125 202

(WHO)
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.

(1)

(3)

(4)

126 202

(5)

127 202

22

128 202

1
2

(Phytohaemagglutinin)

129 202

80

(Cyanogenicglycoside)

130 202

131 202


SARS

132 202

QS QS

()

133 202

57

134 202

AB1B2C P

23
C A

12

12

1.

2.

3.

4.

5.

6. C
C
C
135 202

7.

8.

9.
C

10.

11.

12.

A C

136 202

13

ABCE

10

1
2

7
137 202

8
9

10

108
108

Gmb

138 202

10-15

10

24
48%

139 202

2% 8

5
140 202

60%70%

B E

5 30
141 202

50%

10

A A

142 202

1
2 250

3
4
5
6 90-120

2-3

1-2

10

1-2

143 202

8 VS 8

200
3 230

1%

16%

2-3

A
A

1 10
3

2 5 3

3 10 100
2-3

144 202

10

145 202

10

146 202

2
3

A A
A A

A A

147 202

1
2
3
4
5
6
7

PE

PVDC PVC

PVC

PE

PE PVC

148 202

1
2
3
4
5
6
7
8
149 202

9
10

1
15
1.34
2
10
3

4
5 B1 B1
B1
6

150 202


5-6

2005 6
12 14% 18
27% 1516

+
+
+
+
+
+
+
+
+
+

151 202

4-6
25%-70% 4-5

1 1

1
1 2
12
34
5 5-7

6 7

8 20

1.5

1 2

3 4
5

1 4
152 202

2
4 200

2
12
4 1 3
4

153 202

ABC

DNA

154 202


A E
A E

15 250 250
200 2

C B1B2

6-7

155 202

A C

24

50%
50%

156 202

45

1 5
15 20 1
2 1

3 1

4
157 202

5 20


56
3

1
2
3
4
5
6
710
8
9
10 5
11 8
158 202

12
10 6
13 30
14
15
16
17
18
19
20
21

A
D

30

159 202

12

14

20%

40%

160 202

1
2
3

520

2
161 202



76% 16%

4
????
1????

2 ????

3 ????

25

20

162 202

163 202

2
3

164 202

1
2

1
2

3
4

165 202

3 10-15 25
401

0
5

166 202

1
2

3
10
4
2-5 1 2

167 202

1
2
3

5 C C

1
2



168 202

1
2
3 6

4
5
6

1
2
3
4

169 202

1
2

4 D
5

170 202

ADB
1-2

55
1

2,
3
4
.1

27
3 4

171 202

5 6 7
8
.

1
23 43911
5
67
89
100 10
. 12
3
45
6 7 89
10

11 12 13.

14

15
16 17 18
1920
21 22 23
24
1 2 3
4

BBC
C -

11%
8 67

172 202

200 89

C 1 2 C

1000 1100

173 202

7 C C

8
9

10

11 C
12

13
14 C
C
174 202

C
15 C
C
16

1
2
3

4


5

5%-7%
20 30

175 500
2.5
3-4

175 202

DNA

1
2

3
4
5

6
7
8
9
107 8

1 5 5
2 15 5
3

3
5
4

176 202

5 6 5
12
6 30

300 7 1
510
7 100

8
100
9 5

10 50
250 50

11

B1
177 202

1015

178 202

1 300
2

15 3
5
50
250

1 15

30 1

8
9

250 50

10

1015 1
11

1
500
12 6 2
1 10 1
13

30 500 1 50
50100
14 1

15 20 150250
100

179 202

4
5

2 ()

5
C

7
180 202

8
(

)
9()

10

11

12
13

14

15

16

17
18
A
A
19

181 202

511

58%
25%

90000
1.5

19 VS 19

6
7

9
182 202

10

11

12
13
14

15

16

17

18

19

ABC

183 202

2-3

30
10

52

3
3 4

184 202

A E
B C A
E
B
C
C

1 2
3
4
5
6

7
8

+
30%

10

185 202

1 0.5 1

10 10

(1)
12
12

12 3
4 5

6 7 8

910
11
123
4 5 6

1 2 3

45
67
12 3

4
186 202

12
3 4 1
2
12
34 56
78
9 10 11

121314

,
15,16
17
1819
1,2
3

,2
1 23
45
678
910 11
12
12 c

123
45
67
12
345
6
78
910

187 202

12 c 1
2345
67
8
1

2
12
12

12
3

12
34

6 7
89
1 2 3
1 23
456
7 8
91011
1213
12
345
188 202

6 7
1 c2
34

12

12

3
1 2 3
250

123
456
7 8 9
10 11 12

1314
151617
181920
12
1 2 3

4
567
8910
111213
141516
189 202

171819
2021
222324
25
2627
2829
12
123

4

12
345 6

1 2
34
1 23

456
7
12 k 3
45
6
12 k 3
45
67
8
12
34
5
12

190 202

123
45
67
k
12
123

4
12
12

1 10 30
40 2
123
4
567
123
456
789
1011
12131415
161718

1920

2122
23 24
25 26 b1
27

28

29
3031
123
4567

191 202

8 b1 b2 910
11 12 13
141516
17181920
21 22
23 24 25

26 27

28 29

30 3132

33
34353637

123
456
7 8 9

1011
12
1234
5 6 7
89
c
123
45 6

7 8
9 10

11
1213
12
1

23

192 202

2 3 1
2

12

7
7

193 202

ACE
C
A E
A

20
98 7 94 4 93 7 92 8
914 908 837 74 555
465 376 347 324 324
298 238 163 159 143
74

194 202

QS


3040

195 202

400 300

4


144

196 202

2
3

4
5 0.5%
5

60
90 10 / 15 /
90

C C

197 202

1500 8

44 30% 18.6%
1.6 97% A

21

0.05
0.4 8
100200
1,000

198 202

10

!
4

6 C C

7
199 202

C
8 C

9 C
C
C
10

1.

2.

0
3.

4.

5.
12

,
200 202

International Agency for Research on


CancerIARC

I
I
I F-344
15 30mg/kg B6C3F1 ( 60 120mg/kg)103
I
Boobis
I 2 30mg/kgBW
I
I 3500 mg/kg 500mg
I 1750 ?g
29.2?g/kg( 60kg )

30mg/kgBW 1103 10mg/kg


500mg I 5 ?g
0.083?g/kg( 60kg )
30mg/kgBW 3.6103
I S-9

201 202

?g 2.8?g 4-

0.047?g/kg 80-400mg/kg
1.71068.5106


100000-1000000

100-10000

Saprolegnia

202 202

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