unA 8epllcauon, MlLosls and

Melosls
l. unA sLrucLure
ll. unA repllcauon
lll. Chromosomes
lv. MlLosls
v. 1he Cell Cycle
vl. Melosls
Learnlng CuLcomes
undersLand Lhe properues assoclaLed wlLh
unA sLrucLure.
undersLand how unA ls repllcaLed.
undersLand Lhe sLrucLure of chromosomes.
undersLand how mlLosls resulLs ln geneucally
ldenucal cells.
undersLand how melosls resulLs ln daughLer
cells conLalnlng half Lhe normal cellular unA
conLenL.
8lood Llly vldeo
hup://www.youLube.com/waLch?
v=0o!Zukdperu&playnexL=1&llsL=L7818A4A
392A93163
unA SLrucLure
Secondary SLrucLure- double hellx ls
llke a LwlsLed ladder
1he unA double
hellx ls anu-
parallel
Identify the 5P and 3OH
on both antiparallel
strands!
op-up Cuesuon:

llll ln for yourself:

3'-CCAC1-CP-3'
3'CP-
unA ls double sLranded
Francis Crick and James Watson:
winners of 1962 Nobel Prize for
Medicine.
Rosalind Franklin
1he lnfamous phoLograph 31
Shl Cears and locus on 8epllcauon
Cllcker!
8epllcauon on Lhe lagglng sLrand
A supplemenLary vldeo for you Lo vlsuallze
unA synLhesls on Lhe lagglng sLrand:
hup://www.youLube.com/waLch?
v=9mMLkkyxC3L
Cell dlvlslon ln
prokaryoLes
occurs by blnary
sslon.
revlew of Lhe Cell Cycle"
hup://www.youLube.com/waLch?v=vCv3fv-uZ?l
Anlmal vs. planL cyLoklnesls
ConLrol of Lhe Cell Cycle
WhaL happens when Lhe cell cycle keeps
golng unchecked?
Penrleua Lacks
lmmorLal cells
Melosls Cvervlew
Melosls
Pomologous chromosomes carry dlerenL
verslons of Lhe same genes
Crosslng over makes chlmerlc
chromosomes
karyoLypes are phoLographs of an
lndlvlduals chromosomes
ulsasLer durlng melosls leads Lo
nondls[uncuon
nondls[uncuon aL chromosome 21
Chromosomal AlLerauons can cause defecLs
uouble-sLranded unA ls anu-parallel.
Cne consequence of Lhls properLy ls
LhaL
A. unA repllcauon occurs ln opposlLe dlrecuons
on boLh sLrands.
8. unA ls composed parLly of deoxyrlbose
sugar.
C. unA possesses nlLrogenous bases.
u. unA possesses a sugar-phosphaLe backbone.
Whlch of Lhe followlng properues ls
noL assoclaLed wlLh unA?
A. unA repllcauon ls seml-conservauve.
8. unA possesses a sugar-phosphaLe backbone.
C. 1he prlmary sLrucLure of unA ls ln lLs 3' -3'
sequence.
u. 1he secondary sLrucLure of unA ls llke a
LwlsLed ladder ln whlch Lhe rungs are
nlLrogenous bases.
Whlch of Lhe followlng sLaLemenLs
regardlng chromosomes ls false?
A. Are composed of nuclelc aclds and proLelns
called hlsLones.
8. Can be very ughLly colled lnLo
heLerochromaun.
C. Can be loosely organlzed lnLo euchromaun.
u. Are clrcular ln sLrucLure when exLended.
1he sLage of mlLosls ln whlch
mlcroLubules exLendlng from Lhe poles
of Lhe cell have [usL separaLed
dupllcaLed chromosomes aL Lhe
cenLromere ls whlch of Lhe followlng?
A. rophase
8. MeLaphase
C. Anaphase
u. 1elophase
1he second melouc dlvlslon
accompllshes whlch of Lhe followlng?
A. Separauon of slsLer chromauds.
8. Separauon of homologous dupllcaLed
chromosomes.
C. 8lnary sslon of gameLe cells
u. MlLouc dlvlslon of dlplold cells
nondls[uncuon ls nC1 assoclaLed wlLh
A. When homologous dupllcaLed chromosomes
fall Lo separaLe before Lhe rsL melouc
dlvlslon.
8. When slsLer chromauds fall Lo separaLe
before Lhe second melouc dlvlslon.
C. ln some gameLe cells havlng Lhe lncorrecL
number of chromosomes.
u. Chromosomes havlng lnLernal dupllcauons or
deleuons.