Escolar Documentos
Profissional Documentos
Cultura Documentos
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Our team
Undergraduate Students
Silvia Tamarri • Michela Mirri
Francesca Buganè • Guido Costa
Francesco Pasqualini • Iros Barozzi
PhD student
Alice Pasini
Instructors
Silvio Cavalcanti • Francesca Ceroni
Christine Nardini
Advisors
Emanuele Giordano
Marco Tartagni
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Our Project
• The device can switch on and off at two different thresholds (robustness).
• Hysteresis and bistability are well known features of this kind of systems.
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Lac Operon
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Our Project: applications
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Mathematical Model
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Math Model: system
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Formulas
State Equations
Output Equation
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Analytical Approach...
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Numerical Simulator
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Hysteresis
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Bistability
Induced
Transcription On
Bistability
Uninduced
Transcription Off
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Glucose dependence
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GF P in (mpb)
&"
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$"
!! " ! #
!" !" !" !"
[Glu] ex (µM )
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Biodevice: functioning
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Biodevice
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Composite parts
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Composite parts
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Composite parts
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Intermediates
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Image Acquisition System
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Image Analysis
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Protocol Validation Measures
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Promoters Characterization
Induction Deinduction
TO DO:
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Acknowledgements
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