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FORMULRIO DE ERROS TOTAIS

PERMITIDOS

Cdigo: FX-0004-1
Verso:1

Pg:1/5

TTULO: FORMULRIO DE ERROS TOTAIS PERMITIDOS

CVB Intra- CVB Inter- Impreciso Inexatido


individual individual Permitida Permitida
11-Desoxicortisol (s)
21.3
31.5
10.7
9.5
17-Hidroxiprogesterona (s)
19.6
52.4
9.8
14.0
cido 5-Hidroxi-indolactico (u)
20.3
33.2
10.2
9.7
cido rico (s)
8.6
17.2
4.3
4.8
cido rico (u)
24.7
22.1
12.4
8.3
Adenosina de aminase (s)
11.7
25.5
5.9
7.0
Adrenalina (p)
48.3
--24.2
--Albumina (s)
3.1
4.2
1.6
1.3
Aldosterona (s)
29.4
40.1
14.7
12.4
Aldosterona (u)
32.6
39.0
16.3
12.7
Alfa 1 - Antitripsina (s)
5.9
16.3
3.0
4.3
Alfa 1 - Microglobulinas (u)
33.0
58.0
16.5
16.7
Alfa 1 - Glicoprotena cida (s)
11.3
24.9
5.7
6.8
Alfa 1 - Globulinas (s)
11.4
22.6
5.7
6.3
Alfa 2 - Globulinas (s)
10.3
12.7
5.2
4.1
Alfa 2 - Macroglobulina (s)
3.4
18.7
1.7
4.8
Alfa - Amilase (s)
9.5
29.8
4.8
7.8
Alfa - Amilase (u)
94.0
46.0
47.0
26.2
Alfa - Amilase Pancretica (s)
11.7
29.9
5.9
8.0
ALT - Alanina aminotranspeptidase (s)
4,1
13.6
13.6
Androstenediona (s)
11.5
51.1
5.8
13.1
Anti-Estreptolisina O (s)
7,7
No
Antgeno Associado ao CA Mucinoso
10.1
39.3
5.1
10.1
(MCA) (s)
Antgeno Carcinoembrionrio (CEA)
9.3
55.6
4.7
14.1
(s)
Antgeno prosttico especfico (PSA)
14.0
72.4
7.0
18.4
(s)
Antitrombina III (p)
5.2
15.3
2.6
4.0
Apolipoprotena A1 (s)
6.5
13.4
3.3
3.7
Apolipoprotena B (s)
6.9
22.8
3.5
6.0
AST - Aspartato aminotranspeptidase
11.9
17.9
6.0
5.4
(s)
Basfilos - Contagem (st)
28.0
54.8
14.0
15.4
Beta 2 - Microglobulina (s)
5.9
15.5
3.0
4.1
Beta - Globulinas (s)
10.1
9.1
5.1
3.4
Bilirrubina direta (s)
36.8
43.2
18.4
14.2
Bilirrubina Total (s)
25.6
30.5
12.8
10.0
C3 - Complemento (s)
5.2
15.6
2.6
4.1
C4 - Complemento (s)
8.9
33.4
4.5
8.6
CA 125 (s)
29.2
48.2
14.6
14.1
CA 15.3 (s)
5.7
42.9
2.9
10.8
CA 19.9 (s)
24.5
93.0
12.3
24.0

Analito

Erro Total
Permitido
27.1
30.2
26.5
11.9
28.7
16.7
--3.9
36.7
39.6
9.2
43.9
16.2
15.7
12.6
7.6
15.7
103.7
17.7
36.0
22.6
18.5
21.8
30.0
8.3
9.1
11.6
15.2
38.5
9.0
11.7
44.5
31.1
8.4
16.0
38.2
15.5
44.3

FORMULRIO DE ERROS TOTAIS


PERMITIDOS

Cdigo: FX-0004-1
Verso:1

Pg:2/5

TTULO: FORMULRIO DE ERROS TOTAIS PERMITIDOS

Analito
Cadeia Kappa - Imunoglobulinas (s)
Cadeia Lambda - Imunoglobulinas (s)
Clcio (u 24h)
Clcio Ionizado (s)
Clcio Total (s)
Catecolaminas totais (u 24h)
Ceruloplasmina (s)
Cloretos (s)
Cobre (s)
Colesterol HDL (s)
Colesterol LDL - Direto (s)
Colesterol LDL (s)
Colesterol Total (s)
Colesterol VLDL (s)
Conc. Hb Corpuscular Mdia (CHCM)
(st)
Cortisol (s)
Creatinina - Depurao
Creatinina (s)
Creatinina (u)
Creatinoquinase (CKTotal) (s)
Creatinoquinase MB - Atividade (s)
Creatinoquinase MB - Massa (s)
Enzima Conversora da Angiotensina
(ECA) (s)
Eosinfilos - Contagem (st)
Estradiol (s)
Estradiol (u)
Estradiol livre (s)
Estradiol livre (u)
Fator Reumatide (s)
Fator VIII (p)
Ferritina (s)
Ferro (s)
Fibrinognio (p)
Folato (s)
Fosfatase cida (s)
Fosfatase alcalina (s)
Fosfatos (s)
Fosfatos (u)
Frutosamina (s)
Gamaglobulinas (s)
Gama-Glutamiltransferase (GGT) (s)
Glicose (s)

CVB Intra- CVB Inter- Impreciso Inexatido


individual individual Permitida Permitida
4.8
15.3
2.4
4.0
4.8
18.0
2.4
4.7
26.2
27.0
13.1
9.4
1.7
2.2
0.9
0.7
1.9
2.8
1.0
0.8
24.0
32.0
12.0
10.0
5.7
11.1
2.9
3.1
1.2
1.5
0.6
0.5
4.9
13.6
2.5
3.6
7.1
19.7
3.6
5.2
6.5
--3.3
--8.3
25.7
4.2
6.8
6.0
14.9
3.0
4.0
27.6
--13.6
---

Erro Total
Permitido
8.0
8.6
31.0
2.1
2.4
29.8
7.8
1.5
7.7
11.1
--13.6
9.0
---

1.7

2.8

0.9

0.8

2.2

20.9
13.6
4.3
24.0
22.8
19.7
18.4

45.6
13.5
12.9
24.5
40.0
24.3
61.2

10.5
6.8
2.2
12.0
11.4
9.9
9.2

12.5
4.8
3.4
8.6
11.5
7.8
16.0

29.8
16.0
6.9
28.4
30.3
24.1
31.2

12.5

27.7

6.3

7.6

17.9

21.0
30.4
22.6
22.8
38.6
8.5
4.8
14.9
26.5
10.7
24.0
8.9
6.4
8.5
26.4
3.4
14.6
13.8
4.9

76.4
--24.4
----24.5
19.1
13.5
23.2
15.8
73.0
8.0
24.8
9.4
26.5
5.9
12.3
41.0
7.7

10.5
15.2
11.3
11.4
19.3
4.3
2.4
7.5
13.3
5.4
12.0
4.5
3.2
4.3
13.2
1.7
7.3
6.9
2.5

19.8
--8.3
----6.5
4.9
5.0
8.8
4.8
19.2
3.0
6.4
3.2
9.4
1.7
4.8
10.8
2.3

37.1
--27.0
----13.5
8.9
17.3
30.7
13.6
39.0
10.3
11.7
10.2
31.1
4.5
16.8
22.2
6.3

FORMULRIO DE ERROS TOTAIS


PERMITIDOS

Cdigo: FX-0004-1
Verso:1

Pg:3/5

TTULO: FORMULRIO DE ERROS TOTAIS PERMITIDOS

Analito
Globulina Ligadora da Tiroxina (TBG)
(s)
Globulina Ligadora dos Horm. Sexuais
(SHBG)
Globulinas Totais (s)
Haptoglobina (s)
Hemcias (st)
Hematcrito (st)
Hemoglobina (st)
Hemoglobina A1c (st)
Hemoglobina Corpuscular Mdia
(HCM) (st)
Hemoglobina Glicada (st)
Homocistena (p)
Hormnio Folculo Estimulante (FSH)
(s)
Hormnio Luteinizante (LH) (s)
Hormnio tireoestimulante (TSH) (s)
Ig A (s)
Ig G (s)
Ig M (s)
Insulina (s)
Lactato (st)
Lactato Desidrogenase (LDH) (s)
Leuccitos - Contagem (st)
Linfcitos - Contagem (st)
Lipase (s)
Lipoprotena (a) (s)
Ltio (s)
Magnsio (s)
Magnsio (u 24h)
Mioglobina (s)
Moncitos - Contagem (st)
Neutrfilos - Contagem (st)
Noradrenalina (p)
Osmolalidade (s)
Osteocalcina (s)
pCO2 (st)
Peptdeo C (s)
pH (unidades de pH) (st)
pH [H+] (st)
Plaquetas - contagem (st)
Potssio (s)
Potssio (u)
Pr-albumina (s)

CVB Intra- CVB Inter- Impreciso Inexatido


individual individual Permitida Permitida

Erro Total
Permitido

6.0

6.0

3.0

2.1

7.1

12.1

42.7

6.1

11.1

21.1

5.5
20.4
3.2
2.8
2.8
3.0

12.9
36.4
6.1
6.4
6.6
7.2

2.8
10.2
1.6
1.4
1.4
1.5

3.5
10.4
1.7
1.7
1.8
2.0

8.0
27.3
4.4
4.1
4.1
4.4

1.6

5.2

0.8

1.4

2.7

5.6
9.0

--40.3

2.8
4.5

--10.3

--17.7

10.1

32.0

5.1

8.4

16.7

14.5
19.7
5.4
4.5
5.9
21.1
27.2
8.6
10.9
10.4
23.1
8.5
No
3.6
38.3
13.9
17.8
15.1
19.5
1.3
6.3
4.8
9.3
0.2
3.5
9.1
4.8
27.1
10.9

27.8
27.2
35.9
16.5
47.3
58.3
16.7
14.7
19.6
27.8
33.1
85.8
No
6.4
37.6
29.6
49.8
32.8
--1.2
23.1
5.3
13.3
--2.0
21.9
5.6
23.2
19.1

7.3
9.9
2.7
2.3
3.0
10.6
13.6
4.3
5.5
5.2
11.6
4.3
3.6
1.8
19.2
7.0
8.9
8.1
9.8
0.7
3.2
2.4
4.7
0.1
1.8
4.6
2.4
13.6
5.5

7.8
8.4
9.1
4.3
11.9
15.5
8.0
4.3
5.6
7.4
10.1
21.6
4.2
1.8
13.4
8.2
13.2
9.1
--0.4
6.0
1.8
4.1
--1.0
5.9
1.8
8.9
5.5

19.8
24.6
13.5
8.0
16.8
32.9
30.4
11.4
14.6
16.0
29.1
28.8
10.1
4.8
45.0
19.6
27.9
22.4
--1.5
11.2
5.7
11.7
--3.9
13.4
5.8
31.3
14.5

FORMULRIO DE ERROS TOTAIS


PERMITIDOS

Cdigo: FX-0004-1
Verso:1

Pg:4/5

TTULO: FORMULRIO DE ERROS TOTAIS PERMITIDOS

Analito
Prolactina (s) - Homens
Protena C (s)
Protena C - Reativa (s)
Protena S (p)
Protenas (u)
Protenas totais (s)
PTTa (p)
RDW (Red cell distribution width) (st)
Reticulcitos, contagem (st)
Sdio (s)
Sdio (u)
Sulfato de Deidroepiandrosterona (s)
T3-captao (s)
Tempo de Protrombina (p)
Testosterona (s)
Testosterona (u)
Testosterona Livre (s)
Testosterona Livre (u)
Tireoglobulina (s)
Tiroxina (T4 Total) (s)
Tiroxina Livre (T4 Livre) (s)
Transferrina (s)
Triglicrides (s)
Tri-iodotironina (T3) (s)
Tri-iodotironina Livre (T3 Livre) (s)
Uria (s)
Uria (u)
VMA (u 24h)
Volume Corpuscular Mdio (VCM) (st)
Volume Plaquetrio Mdio (VPM) (st)
Zinco (p)
Zinco (s)

CVB Intra- CVB Inter- Impreciso Inexatido


individual individual Permitida Permitida
6.9
61.2
3.5
15.4
5.8
55.2
2.9
13.9
52.6
84.4
26.3
24.9
5.8
63.4
2.9
15.9
39.6
17.8
19.8
10.9
2.7
4.0
1.4
1.2
2.7
8.6
1.4
2.3
3.5
5.7
1.8
1.7
11.0
29.0
5.5
7.8
0.7
1.0
0.4
0.3
24.0
26.8
12.0
9.0
11.6
49.0
5.8
12.6
4.5
4.5
2.3
1.6
4.0
6.8
2.0
2.0
9.3
23.7
4.7
6.4
17.3
28.8
8.7
8.4
9.3
--4.7
--51.7
--25.9
--13.0
25.0
6.5
7.0
6.0
12.1
3.0
3.4
7.6
12.2
3.8
3.6
3.0
4.3
1.5
1.3
20.9
37.2
10.5
10.7
8.7
14.4
4.4
4.2
7.9
--4.0
--12.3
18.3
6.2
5.5
22.7
25.9
11.4
8.6
22.2
47.0
11.1
13.0
1.3
4.8
0.7
1.2
4.3
8.1
2.2
2.3
9.3
9.4
4.7
3.3
11.0
14.0
5.5
4.5

Erro Total
Permitido
21.1
18.7
68.3
20.7
43.5
3.4
4.5
4.6
16.8
0.9
28.8
22.2
5.3
5.3
14.0
22.7
----17.8
8.3
9.9
3.8
27.9
11.4
--15.7
27.3
31.3
2.3
5.8
11
13.5

Legenda
CVB Intra-individual - Coeficiente de Variao Biolgica em um mesmo indivduo (CV w)
CVB Inter-individual - Coeficiente de Variao Biolgica entre indivduos (CV g)
(s) - soro; (p) - plasma; (st) - sangue total; (u) urina
(p) - plasma
(st) - sangue total
(u) - urina

FORMULRIO DE ERROS TOTAIS


PERMITIDOS

Cdigo: FX-0004-1
Verso:1

Pg:5/5

TTULO: FORMULRIO DE ERROS TOTAIS PERMITIDOS


Como so calculados os requisitos para a qualidade usando a variao biolgica
Impreciso Mxima Permitida I < 0.5 CVw
2

2 1/2

Inexatido Mxima Permitida B < 0.25 (CVw + CVg )


2

2 1/2

Erro Total Permitido ET < k. 0.5 CVw+ 0.25(CVw + CVg )

sendo k= 1.65 (

=0.05)

Referncia:
1. RICOS, C.; ALVAREZ, V.; CAVA, F.; GARCIA-LARIO, J. V.; HERNANDEZ, A.; JIMENEZ, C. V.;
MINCHINELA, J.; PERICH, C.; SIMON, M. Current databases on biologic variation: pros, cons and
progress. Scand J Clin Lab Invest 1999; 59:491-500.
http://www.westgard.com/biodatabase1.htm#albumin