Biosafety-EMS - Glove Protection and Selection Guide.12 - 08

University of Colorado at Boulder Department of Environmental Health and Safety
Glove Protection and Selection Guide

INTRODUCTION Hand protection is very important when working with hazardous chemicals, radioactive materials, and bloodborne pathogens or other potentially infectious materials. Gloves provide a chemical resistant barrier between the worker's hands and the reagent, but some chemicals can breach the barrier provided by the glove material. Any protective glove should be selected according to the chemical being handled and the nature of the lab operations. Gloves are disposed of when overtly contaminated or when the integrity of the glove is compromised, and removed when work is completed. Disposable gloves should never be washed, reused, or used for touching "clean" surfaces (keyboards, telephones, etc.), and they should not be worn outside the lab. Alternatives to powdered latex gloves should be available. Hands should always be washed following removal of gloves. Proper disposal of gloves is important. Gloves must be segregated and disposed of based on the chemical or material being handled. For questions, please consult with your Environmental Health and Safety department. HOW TO SELECT THE BEST GLOVE:
1. Evaluate the physical conditions you will subject the glove to and determine which types
of resistance are more important: abrasion, cut, puncture, temperature, etc. Physical conditions can influence chemical resistance. 2. Consider features you need for your application: grip, length, dexterity, comfort, insulation, type of cuff, extent of coating. Glove manufacturers offer a variety of styles to best suit your application. There are also several different cuff designs to suit your application requirements. There are knit wrist cuffs, designed to keep the glove firmly in place. This prevents debris from entering the glove and enhances warmth. 3. Select the glove that offers you the optimum combination of features, benefits and resistance to both physical and chemical hazards. 4. For chemical-resistance needs, refer to the Glove Chemical Resistant Guide listed below and the additional references. 5. Select a thinner-gauge unsupported glove when you require extra dexterity and tactile sensitivity. Choose a heavier-gauge unsupported glove for greater protection and wear. Consider a flock lined, unsupported glove for extra comfort, insulation and wear. Choose a supported or cut-and sewn glove for added cut, snag, and puncture or abrasion resistance.
Department of Environmental Health and Safety 1000 Regent Drive 413 UCB University of Colorado Boulder, Colorado 80309-0413 303 492 6025
Biosafety-EMS.Glove Protection and Selection Guide.12_08
Page 1 of 9
Donnelly 02/25/04, Donnelly rev.12/09/08
6. Choose the finish you need for the grip necessary for your application: rough, smooth, wrinkle, embossed bisque, etc. Note: Some gloves have no special grip finish, yet still provide good gripping power due to intrinsic properties of the particular glove polymer. 7. Select glove length by determining the depth to which your hand and arm will be immersed in a solution and the extent to which you need splash protection. 8. Select the size that gives you the right fit, dexterity and comfort. To determine your size, measure the circumference around the palm area. This is your glove size. For example, 7" is equal to a size 7 glove. (XS = 6-7, S = 7-8, M = 8-9, L = 9-10, XL = 10-11). 9. For product protection, consider the toughness, fit, thickness and degree of disposability required. Select the style that provides the most important of these features and benefits. 10. Always inspect your gloves before using them. Of principal concern are cuts, tears and punctures. Discoloration or stiffness may indicate non-uniformities in the rubber or plastic or chemical attack resulting from previous use. 11. Glove colors can often be used to help identify contamination or to designate critical work areas. Select the style most suited to your needs. BLOODBORNE PATHOGENS AND OTHER POTENTIALLY INFECTIOUS AGENSTS 1. Gloves are worn when hands may contact bloodborne pathogens, other potentially infectious materials, contaminated surfaces or equipment. 2. Wearing two pairs of gloves may be appropriate. 3. Gloves are disposed of when overtly contaminated or when the integrity of the glove is compromised, and removed when work with infectious materials is completed. 4. Disposable gloves should never be washed, reused, or used for touching "clean" surfaces (keyboards, telephones, etc.), and they should not be worn outside the lab. 5. Alternatives to powdered latex gloves should be available. 6. Hands should always be washed following removal of gloves.
Department of Environmental Health and Safety 1000 Regent Drive 413 UCB
University of Colorado
Boulder, Colorado 80309-0413 303 492 6025
Page 2 of 9
CHEMOTHERAPEUTIC AGENTS One of the most frequently used treatments for cancer is chemotherapy. Unfortunately it is well known that chemotherapeutic (cytostatic) agents are potentially hazardous for the manipulator. Chemotherapeutics are known to be: Carcinogenic Mutagenic Teratogenic It is important to wear the appropriate personal protective equipment when working with chemotherapeutic agents and this includes selecting a disposable glove that will protect against the adverse affects of these chemicals. Medical gloves with a chemotherapy claim should meet an appropriate FDA-recognized consensus standard for medical gloves or an equivalent test method. Physical features such as increased thickness and length make these gloves more suitable for the safe handling of chemotherapy agents (usually minimal thickness of 0.10 mm, minimal length of 270 mm). Gloves for use with chemotherapy agents should also undergo the standard biocompatibility testing for medical gloves. Ansell Cytostatic Permeation Program http://150.101.90.21/mam_asset/Cytostatics%20brochure%20EN.pdf?id=01ffa7c0646b3fb20 00001041cc543c9&col=/client_db/ANSL&ext=jpg&type=pdf NIOSH - Preventing Occupational Exposure to Antineoplastic and Other Hazardous Drugs in Health Care Settings, September 2004 http://www.cdc.gov/niosh/docs/2004-165/pdfs/2004-165.pdf
DEFINITIONS Breakthrough Time - The time which elapses between initial contact of a chemical with the outside surface of a protective material and when the chemical can be detected at the surface of the material. Degradation - A reduction in one of physical properties of a glove or protective clothing. Permeation - Process by which a chemical can pass a protective film without going through pores, or other visible openings (e.g., what happens to air in an inflated balloon after several hours -- same principle).
Page 3 of 9
GLOVE CHEMICAL RESISTANCE GUIDE

Silver Shield (2) (4 Mil) CHEMICAL
Acetaldehyde Acetone Acetonitrile Acrylic Acid Acrylonitrile Aldehyde Aniline Benzaldehyde Benzene Benzoyl Chloride Bromobenzene Butyl Acetate p-t Butyltoluene Butyraldehyde Carbon Disulfide
Degradation Breakthrough (D) (BT)
(1)
Viton (2) (9 Mil)

D P P ID G F P G F G E E P E P E BT 0m ID ID 5.9h 1m 0m 10m 9.9h 6h >8h 8h ID >8h 54m >8h PR 281.9 ID ID 0.23 176 281.9 18.7 4 0.012 ND ND ID ND 9 ND D E E E E G E F E P F P G G E P
Butyl (2) (17 Mil)

BT 9.6 >17h >8h >8h 3.1h 9.5h >8h 9h 31m 6.2h 32m 1.9h 1.7h >15h 7m PR 0.07 ND ND ND <0.01 0.07 ND ND 32.3 16.6 39.8 7.61 8 ND 98
Nitrile (2) (11 Mil)

D F P ID F P P P P P P P P P P P BT 4m ID ID ID 3m 4 1.1h ID ID ID PR
Neoprene (2) (22 Mil)

D BT 21m 12m 40m ID ID ID >8h ID 16m ID ID 52m ID ID ID PR 18 35 7 ID ID ID D ID
PVC (2) (20 MIL)

BT ID >> PR
Permeation Rate (PR)
E E E ID E E E ID E ID E E E E G
>6h >6h >8h ID ID >6h >8h ID >8h ID ID >6h >8h ID >8h
ND ND ND ID ID ND ID ID ND ID ID ND ND ID ND
161 E ID ID ID E E ID
P >1m ID ID ID ID ID ID ID ID
176 ID 161 ID 45 ID ID ID E ID ID ID
ND G >8h ID ID ID
ND
133 ID 2m ID ID 53 ID ID ID ID ID ID ID ID ID ID ID ID ID ID ID
250
13m 9.1 ID 29m 54.4 ID ID ID 1m ID ID 51 ID ID ID
Page 4 of 9

Carbon Tetrachloride Cellosolve Chlorobenzene Chloroform Chloronaphthalene Chloroprene Cyclohexane Cyclohexanol Cyclohexanone Dibutylphthalate 1,1,Dichloroethane 1,2,Dichlorothane Diethylamine Diethylaminoethanol 1,4-Diethylene Dioxide Diethyleneltriamine Diisobutyl Ketone 80% Dimethyl Acetamide Dimethyl Formamide Dimethylsulfoxide
Degradation (D) Breakthrough Permeation (BT) Rate (PR)
Viton (2) (9 Mil)

D E F E E E ID E E P E G E P E P E F P P F BT PR D P G P P P P P E E E ID P P E E E G ID E E
Butyl (2) (17 Mil)

BT ID ID PR ID ID D G P P P P ID P E P E P P F E P P F ID F F

BT 3.4h ID ID 4m 2.9h ID ID >16h ID >16h ID 8m ID >8h 28m ID 3h ID 1m ID PR 5 ID ID 352
Neoprene
(2)
(22 Mil)
D BT PR D
PVC (2) (20 MIL)

BT ID ID ID ID ID ID 16m ID ID ID ID ID ID ID 8m ID ID ID ID ID 250 17 PR
E G E P E ID E E E E ID E E E ID ID E ID E G
>6h >6h ID 10m >8h ID >6h >6h >6h >6h 2.4h >6h >8h ID >8h ID >6h 1.5h >8h ID
ND ND ID O.OO9 ND ID ND ND ND ND 6 ND ND ID ND ID ND 0.728 ND ID
>13h ND ID >8h ID ND
F 31m 252 ID E 5.9h ID ID 3 ID ID ID
35m 308 ID ID 28m ID ID 18
9.5h 0.46 >16h ND >8h >7h >8h ND ND ND
P 12m 220 ID ID ID ID ID 7 ID ID ID ID ID ID ID ID ID ID ID
>1.3 ID ID ID ID
1.1h 20.3 >11h ND >16h ND >16h ND ID 2h 47m >8h ID 53 46 ND
E 2.7h ID ID ID ID
ND ID ID ID
29m 86.3 >8h 1.5h 6.9 ND 31 0.81
ND ID ID 311 ID ID
P 33m 247 ID ID ID ID ID ID ID ID ID ID ID ID ID ID
35m 852 >8h ND
ND ID
23m 26.8 >8h ND
>20h ND >8h ND
77.1 ID 28m 62 ID ID ID ID ID ID ID ID ID ID ID ID
1.2h 90.6 25m 8m 1.5h 3 6.5 5
3.3h 41.2 >8h >8h >8h ND ND ND
48.9 ID ID ID
>15 ID ID ID
Page 5 of 9

Dioxane Divinyl Benzene Divinyl Benzene Epichlorohydrin Ether Ethyl Acetate Ethyl Ether Ethylamine 70% Ethylene dibromide Formaldehyde 37% Furan Furfural Glutaraldehyde n-Hexane Hydrazine 70% Hydrochloric Acid 37% Hydrofluoric Acid 50% Isobutyl Alcohol Isobutyraldehyde Methacrylic Acid
Degradation (D) Breakthrough Permeation D (BT) Rate (PR)
Viton (2) (9 Mil)

BT 23m PR 26.8 ND ND 4 21.5 ID 21.5 ID ND ND 23 14.8 ND ND ID ID ID ND 11.5 ND D E F F G P G P E F E P E E P E E F E E G
Butyl (2) (17 Mil)

BT >20h 2.2h 2.2h >8h 8m 7.6h 8m >12h 3.3h 16h 1.3h >16h >8h ID >8h ID ID >8h >8h >8h PR ND 238 238 ND 92.2 3.4 92.2 ND 6 ND 10 ND ND ID ND ID ID ND ND ND D P P P P P P P F P E P P P E G P P G P P

BT 28m ID ID ID 14m 8m 14m 1.1h ID >21h ID 28m ID ID >8h ID ID >8h ID 1.7h PR 77.1 ID ID ID 21.8 145 21.8 30.1 ID ND ID 265 ID ID ND ID ID ND ID 23 D ID ID ID ID ID G E ID ID E ID ID ID E E E E ID ID ID

BT 28m ID ID ID ID 34m 18m ID ID >8h ID ID ID 39m >8h >8h >8h ID ID ID PR 62 ID ID ID ID 178 51 ID ID ND ID ID ID 5 ND ND ND ID ID ID D
PVC (2) (20 MIL)

BT PR
E E E ID ID E ID E E E ID E E E G E G E E ID
>8h >8h >8h ID >6h >6h >6h 47m ID >6h ID >8h ID >6h >6h >6h >6h ID ID ID
ND ND ND ID ND ND ND 7.64 ID ND ID ND ID ND ND ND ND ID ID ID
ID ID ID ID ID ID ID ID ID G ID ID ID ID E E E ID ID ID
8m 250 ID ID ID ID ID ID ID ID 8h ID ID ID ID 8h ND ND
E >17h E >17h P 2h
P 12m P ID
P 12m P E ID >8h
E >16h P 20m F E 3.6h >8h
ID >11h P E G E P F ID ID ID >8h 4m >8h
>8h ND 1.8h ID ID ID 0
Page 6 of 9

Methacrylonitrile Methyl Chloroform Methyl Cyanide Methyl Ethyl Ketone Methyl Isocyanate Methylamine 40% Methylene Chloride Methylene Dianiline Methylene Dichloride Morpholine Nitric Acid, 3 Molar Nitrobenzene Nitropropane Oxalic Acid PCB, Aroclor 1254 50% Pentachlorophenol 1% (3) n-Pentane Perchlorethylene Phenol 85%, water sat Propyl Acetate
Viton (2) (9 Mil)

BT 4m PR 462 ND ID ID 121 ND 7.32 ND 7.32 97 ID ND 26.1 ND ND ND ND ND ND ID D G P E E P E P E P E F E E E P P P P E G
Butyl (2) (17 Mil)

BT 6.8h ID >8h >8h 1.1h >15h 24m >24h ID >16h ID >23 >8h >8h ID ID ID ID >20h 2.7h PR 0.001 ID ND ND 9 ND 133 ND ID ND ID ND ND ND ID ID ID ID ND 2.86 D P P ID P P G P F P P P F P G F E E F P P

BT 7m 41m ID ID ID >8h 4m ID 4m 48m ID 33m 16m ID ID >13h ID >1.3h 39m 17m PR 560 76.4 ID ID ID ND 766 ID 766 206 ID 1.7 29.5 ID ID ND ID 5.5 >1500 72.5 D ID P E G ID ID F ID ID ID E G ID ID ID ID ID ID E ID

BT ID 27m 40m 22m ID ID 6m ID ID ID >8h 1h ID ID ID 8h 38m 28m >8h ID PR ID 197 7 155 ID ID 239 ID ID ID ND 20 ID ID ID ND 3 75.5 ND ID D
PVC (2) (20 MIL)

BT ID ID ID 1m ID ID ID ID ID ID 1.9h ID ID ID ID ID 9m ID 32m 13 ID 17 0 >> PR
E ID ID E ID F G E ID E E E E E E E E E G E
ID >6h >8h >24h ID 1.9h >8h >24h 1.9h >8h >6h >8h >8h >8h >8h >8h >6h >6h >6h >6h
ID ND ND ND ID 2 ND ND 0.002 ND ND ND ND ND ND ND ND ND ND ND
ID ID ID ID ID ID ID ID ID ID E ID ID ID ID ID ID ID ID ID
E >15h ID P P ID ID 4m
E >16h F E 1h >8h
G 1.9h G G ID >8h
E 21m P E >8h >8h
E >13h ID >8h E >17h E >15h E P ID ID
Page 7 of 9

Propyelenediamine Pyridine Red Fuming Nitric Acid Sodium Hydroxide 50% Styrene Sulfuric Acid, 3 Molar Tetrachloroethylene Tetraethylenepentamine Tetrafluoroethylene Tetrahydrofuran Thiophene Toluene Toluene Diisocyanate Trichloroethane 1,1,1 Trichloroethane 1,1,2 Trichloroethane Triethylamine Vinyl Chloride Xylene
Viton (2) (9 Mil)

BT PR ND 74 ID ID ID ID ND ND ND 327 ND ND ND 0.24 ND ND ND D E G P E P G P E E F P F E P P P P P P
Butyl (2) (17 Mil)

BT >8h >8h ID ID ID ID ID >8h >8h 31m 1.8h 21m >8h 18m ID 5.7h ID ID ID PR ND ND ID ID ID ID ID ND ND 112 17 22.1 ND 550 ID 7 ID ID ID D F P P G P P F F ID P P P G P F P E G P

BT ID ID ID ID ID ID 1.3h ID ID 4m ID 11m 3.7h 8m 41m ID >8h 5.7h ID PR ID ID ID ID ID ID 5.5 ID ID 167 ID 68.1 1.8 283 76.4 ID ND 0.14 ID D ID ID ID E ID E ID ID ID P ID ID ID ID P ID ID ID ID

BT ID 28m ID >6.7h ID >6.7h 28m ID ID 11m ID 14m ID 11m 27m ID ID ID 23m PR ID 117 ID ND 40 ND 75.5 ID ID 671 ID 576 ID 881 197 ID ID ID 135 D
PVC (2) (20 MIL)

BT ID 1m ID 8h ND >> PR
ID ID P E G E E ID E E ID E E E E ID ID E E
ID ID 35m >6h >4h >6h >6h ID ID >8h >6h >6h >8h >6h >6h ID ID >8h >24h
ID ID ID ND ND ND ND ND ID ND ND ND ND ND ND ID ID ND ND
E 38m P P G G E ID ID ID ID ID
ID ID ID E ID E ID ID ID ID ID ID G ID ID ID ID ID ID
27m 40 >8h ND ID ID ID 1m ID ID ID >> ID
E >17h E E P E >8h >8h 4m >8h
E >16h E >16h G 7.4h E >15h E E >8h >8h
3m 350 >6.7 ND ID ID ID ID ID ID ID ID ID ID
G 4.4h 0.098 E >8h ND
4m 383
Page 8 of 9
(1) Van Nostrand Reinhold publishing.
(2) The data for Silver ShieldTM, VitonTM, Butyl and Nitrile gloves were provided by Siebe North Inc, Charleston, SC; information on Neoprene and Polyvinyl Chloride (PVC) gloves were supplied by Pioneer Industrial Products, Williard, OH. (3) In Kerosene E = Excellent; G = Good; F = Fair; P = Poor; ND = None detected; ID = Insufficient Data; D = Degradation; BT = Breakthrough, amount of elapsed time after initial exposure before the chemical can be analytically detected on the inside surface of the glove; PR = Permeation Rate is expressed in mg/m2/sec. PR can be used for estimating glove thickness required; for a given material, thicker is more resistant. Note: Silver Shield gloves may be worn as liners under other glove types to enhance protection.
Additional Glove Chemical Resistance Guides: Ansell Healthcare Chemical Resistance Guide, 8th edition http://www.ansellpro.com/download/Ansell_8thEditionChemicalResistanceGuide.pdf BEST Glove Manufacturing http://www.bestglove.com/site/chemrest/
NIOSH: Recommendations for Chemical Protective Clothing - A Companion to the NIOSH Pocket Guide to Chemical Hazards http://www.cdc.gov/niosh/ncpc/ncpc2.html
Page 9 of 9

Biosafety-EMS - Glove Protection and Selection Guide.12 - 08

Enviado por

Dados do documento

Descrição original:

Título original

Direitos autorais

Formatos disponíveis

Compartilhar este documento

Compartilhar ou incorporar documento

Opções de compartilhamento

Você considera este documento útil?

Este conteúdo é inapropriado?

Direitos autorais:

Formatos disponíveis

Biosafety-EMS - Glove Protection and Selection Guide.12 - 08

Enviado por

Direitos autorais:

Formatos disponíveis

University of Colorado at Boulder Department of Environmental Health and Safety

Glove Protection and Selection Guide