Manufacturer Contents Indications

Fahrenheit Paracetamol Headache, fever, myalgia & toothache. For the short-term treatment of moderate pain (esp after surgery) & fever. When administration by IV route is clinically justified by an urgent need to treat pain & hyperthermia, &/or when other routes of administration are not possible. Tab Adult & childn >12 yr 1 tab, 6-12 yr tab, 3-5 yr tab. To be taken 3-4 times daily. Infusion Adult & adolescent w/ >50 kg body wt 100 mL IV infusion for 15 min up to 4 times daily. Max daily dose: 4 g. Adult & adolescent <50 kg, childn w/ >33 kg body wt (approx 11 yr) 1.5 mL/kg body wt up to 4 times daily. Max daily dose: 60 mg/kg body wt or 3 g. Doses should be given w/ at least 4 hr interval. May be taken with or without food. Severe hepatocellular insufficiency.

Dosage

Administration Contraindications

Renal & hepatic failure. Increase risk of liver damage w/ doses higher than recommended. Hepatocellular insufficiency, severe renal insufficiency Special Precautions (CrCl <30 mL/min), chronic alcoholism, chronic malnutrition (low reserves of hepatic glutathione), dehydration. Pregnancy. Adverse Drug Reactions Hematological, skin reactions, other allergic reactions. Malaise, hypersensitivity reaction, hypotension, increased level of hepatic transaminase, thrombocytopenia, leucopenia, neutropenia. View ADR Monitoring Form Alcohol, oral anticoagulants, chloramphenicol, aspirin, phenobarb, liver enzyme inducers, hepatotoxic agents. Clearance may be reduced by probenecid. Elimination may be prolonged by salicylamide.

Drug Interactions

Pregnancy Category PO: B (US FDA) MIMS Class ATC Classification Analgesics (Non-Opioid) & Antipyretics N02BE01 - paracetamol ; Belongs to the class of anilide preparations. Used to relieve pain and fever.

Drug Classification Tab: B; infusion: G Presentation/Packing Form Packing/Price Farmadol inj 10 100 mL x 1's mg/mL Farmadol tab 500 mg 10 10's (Rp25000.00/box)

Sagestam Injection

Manufacturer Contents Indications Dosage Contraindications Special Precautions Adverse Drug Reactions Drug Interactions Pregnancy Category (US FDA) MIMS Class ATC Classification Drug Classification Presentation/Packing

Related Information: Abbreviation Index Manufacturer Sanbe Contents Indications Dosage Contraindications Adverse Drug Reactions Drug Interactions Gentamycin sulfate Bacterial infections caused by susceptible pathogens esp gm-ve bacilli. IM/IV Adult Serious infection 3 mg/kg body wt/day in 3 equal doses 8 hrly. Life-threatening infection Up to 5 mg/kg body wt/day in 3 or 4 equal doses. Childn 2-2.5 mg/kg 8 hrly. Neonate & infant >1 wk 2.5 mg/kg 8 hrly, Premature or full-term neonate 1 wk 2.5 mg/kg 12 hrly. Hypersensitivity to aminoglycosides. Nephrotoxicity, neurotoxicity, anemia, purpura, fever. View ADR Monitoring Form Increases nephrotoxicity w/ cephalosporins.

Special Precautions Neuromuscular disease, renal impairment. Elderly. Pregnancy.

Pregnancy Category Category D: There is positive evidence of human foetal risk, but the (US FDA) benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious

disease for which safer drugs cannot be used or are ineffective). MIMS Class ATC Classification Aminoglycosides J01GB03 - gentamicin ; Belongs to the class of other aminoglycosides. Used in the systemic treatment of infections.

Drug Classification G Presentation/Packing Form Sagestam Injection 40 mg/mL

Packing/Price 2 mL x 5 1's (Rp38950.00/box)

Scelto

Manufacturer Contents Indications Dosage Contraindications Special Precautions Adverse Drug Reactions Drug Interactions Pregnancy Category (US FDA) MIMS Class ATC Classification Drug Classification Presentation/Packing

Related Information: Abbreviation Index Manufacturer Pharos Contents Indications Dosage Ketorolac tromethamine Short-term management of moderately severe acute pain following surgical procedures. Adult Initially 10 mg via slow & deep IM or IV bolus over <15 sec, then 1030 mg every 4-6 hr, when required. Max: 90 mg daily for 2 days.

Contraindications Special Precautions Adverse Drug Reactions Drug Interactions

Active peptic ulcer, CV disease, haemorrhagic diathesis, complete or partial syndrome of nasal polyps, angioedema, bronchospams, hypovolaemia, asthma, moderate & severe renal impairment. Impaired hepatic & renal function, fluid retention & oedema, coagulation disorder. Pregnancy & lactation, childn <16 yr. GI pain, dyspepsia, nausea, headache, diarrhoea, dizziness, drowsiness, oedema, inj site pain. View ADR Monitoring Form Warfarin, ACE inhibitors, diuretics, nephrotoxic agents, antiepileptic & psychoactive drugs.

Pregnancy Category (US FDA)

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

(in 3rd trimester or near delivery) Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). MIMS Class Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) M01AB15 - ketorolac ; Belongs to the class of acetic acid derivatives and ATC Classification related substances of non-steroidal antiinflammatory and antirheumatic products. Drug Classification G Presentation/Packing Form Scelto infusion 10 mg/mL Scelto infusion 30 mg/mL

Packing/Price (amp) 5 1's (Rp108000.00/box) 5 1's (Rp158000.00/box)