MPP1

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MICROPLATE
PROCESSOR
3000
SERVICE
MANUAL
Service instructions for the Microplate Processor 3000.
Date of printout of this manual: 21 September, 1994
note : Specifications may be modified without prior notification.
Every effort has been made to avoid errors in text and diagrams. However, Organon Teknika assumes no responsibility for any errors which may appear in this publication. It is the policy of Organon Teknika to improve products as new techniques and components become available. Organon Teknika therefore reserves the right to change specifications at any time. We appreciate any comments on this publication. Organon Teknika Document Date printout Code : 07625
of this manual : 21 September, 1994
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CONTENTS
Table of contents
1. Introduction __---__-___-----------__________________-_____________________-------------------------
1 1 2 2
1.1. Service philosophy 1.2. Update of the manual 1.3. Status of the MPP 3000 2. General description 2.1. Functional 2.1.2. Transport
5 ____________--__________________________-------------------------------------description module 6 7 7 7
- 9
2.1.1. Central control system 2.1.3. Chemical processing module

3. Technical description ____________________------------------------------------------------------
3.1. Hardware
overview of the modules
10 10 11 11 11 12 12 14 16 19 20 23 27 29 29 30 32 module 32 34 34
3.2. Detailed description 3.2.1. Power supplies 3.2.1.1. UPS module
3.2.1.2. + SVolt, + /-15Volt Power Supply 3.2.1.3. + 24Volt Power Supply 3.2.1.4. Power distribution 3.2.2. Incubator module 3.2.3. Washer module 3.2.4. Container module 3.2.5. Dispense module 3.2.5.1. Dispense reagent door 3.2.6. Reader module 3.2.7. Transport 3.2.7.2. Grab 3.2.7.3. Plate carrier label 3.2.7.4. Plate Input/Output 3.2.7.5. Alert board 3.2.7.6. Transport system boards system 3.2.7.1. Arm assembly
CONTENTS
4. Installation
~~~~~-----~ 37 procedure ___________-____________________________---------------------requirements 37 37 37 37 41 42 42 51 55 or update 57 59

-- : ;. ; ;
4.1. Environmental
4.2. Power requirements 4.3. Incoming Inspection 4.4. Pre-installation 4.6. Hardware 4.7. Transport check-lists 4.5. Contents of the sales package installation tools protections 4.6.1. Required
4.8. Repacking instructions 4.9. MPP control software installation 4.10. UNIX 5. Introduction installation on the hard drive
to Calibration
____-_-_______---___---------------------------------------------- 83 83 85 89 90 91 file 68
: i . -r
5.1. Grab calibration 5.2. Calibration of module positions 5.3. Single module position calibration 5.4. Some useful1 Unix commands 5.5. Unix shutdown procedure 5.6 Repairing the MPP-IM.cfg 6. Introduction to Troubleshooting
____--___-__________---------------------------------------93 94 95 96 96 97 97 97 99 103 105 109 113
6.1. Positions duration test 6.2. Module functions duration test 6.3. Quality control test 6.4. IM shutdown procedure 6.5. The Bitbus monitor 6.5.1. Startup procedure 6.5.2. General information 6.5.3. Bitbus commands for Transport system 6.5.4. Bitbus commands for Incubator modules 6.5.5. Bitbus commands for Washer module 6.5.6. Bitbus commands for Dispense module 6.5.7. Bitbus commands for Reader module
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----
-.
CONTENTS
7. Maintenance
.____---__---__-------------------------- _---______-___--__------------------------- 115 115 115 116 117 121 _____________-____-_____________________--------------------------121 123 __-____-____________-------------------------127 127 128 128 130 132 135 136 140 143 143 147 152 154 158 167 171 171 175 181 185 189 192 192 materials and parts
7. General information 7.1. Required 7.2. Procedure 7.3. Checklist 8. Cleaning and disinfection 8.2. Disinfection
8.1. Cleaning procedure procedure
9. Introduction
to Replacement instructions tools
9.1. Recommended 9.2. Panels
9.2.1. The back panel 9.2.2. The top cover 9.2.3. The front panel 9.2.4. Left side panel 9.2.5. Right side panel 9.2.6. The front sliding doors 9.3. Chemical modules 9.3.1. Incubator module 9.3.2. Washer module 9.3.2.1. Washer sub-modules 9.3.3. Container unit 9.3.4. Dispense module 9.3.5. Reader module 9.4. Transport modules module positioner 9.4.1. Input/Output 9.4.2. Transport 9.4.3. The Grab 9.4.4. Position and/or Motor Control board 9.4.5. Label decoder board 9.5. Power supplies 9.5.1. The UPS
CONTENTS
9.5.2. The + 5Volt and + /-15Volt power supply 9.5.3. The + 24Volt power supply 9.6. The Control system 9.6.1. The computer 9.6.2. Internal Controller 10. Spare Part Information boards
195 198 202 202 206
__-____________---__________________ -_______________-________________ 213
--- ________________________________________---------------------219 11. Diagrams _--_______________ Fig. 11.1. Diagram Internal Controller Fig. 11.1.1. Layout Internal Controller Fig. 11.2. Diagram Internal Controller Fig. 11.2.1. Layout Internal Controller Fig. 11.3. Diagram Incubator board Fig. 11.3.1. Layout Incubator board Fig. 11.3.2. Diagram and layout Sensor interconnection Fig. 11.4. Diagram and layout Container sensor board Fig. 11.5. Diagram Washer control board Fig. 11.5.1. Layout Washer control board Fig. 11.6. Diagram Washer power board Fig. 11.6.1. Layout Washer power board Fig. 11.7. Diagram Dispense control board Fig. 11.7.1. Layout Dispense control board Fig. 11.8. Diagram Pump control board Fig. 11.8.1. Layout Pump control board Fig. 11.9. Diagram and layout Transmitter Fig. 11.10. Diagram and layout Alert board Fig. 11.11. Diagram Plate I/O board Fig. 11.11.1. Layout Plate I/O board Fig. 11.12. Diagram Position control board Fig. 11.12.1. Layout Position control board Fig. 11.13. Diagram Motor control board Fig. 11.13.1. Layout Motor control board Fig. 11.14. Diagram and layout Filter board Fig. 11.15. Diagram and layout Position interconnection Fig. 11.16. Diagram and layout Grab sensor board board and Receiver board board board board board, stripped version board, stripped version 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246
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_.---I.-_l.-
CONTENTS
Fig. 11.17. Diagram Grab control board Fig. 11.17.1. Layout Grab control board
12.
247 248
-----------------------------------------249
Technic-1
Notes
_________________________________
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12.1. TN Index
249
INTRODUCTION
1. Introduction
The target of this service manual is to provide the service technician with technical background information about Organon Teknikas MICROPLATE PROCESSOR 3000
The Microplate Processor, or MPP 3000, is an automatic device for processing microplates. The operating manual of the Microplate Processor, available under article code 07624, provides the operating principles and procedures that enable optimum use of the MPP 3000 by the user and/or technician. This manual contains : Technical description of the instrument Detailed installation instructions General service procedures Trouble shooting procedures Spare part information Drawings and diagrams This service manual is only applicable for :
MPP 3000 model 3000018/01, version 220V/50Hz and model 3000017/01, version 120V/60Hz with software release 1.1 1.1. Service PhilosoDhr Repair of the MPP 3000 at the customers location should only be done by means of a complete module exchange. This decreases the time the MPP 3000 is nonfunctional. Only where mentioned service can be done, based on sub-module exchange, by the service organisation of the National Companies. No attempt shall be made to repair or modify printed circuit boards. Electronic circuits have to be repaired by exchanging the complete printed circuit boards and mechanical repairs must be done by exchanging the complete assemblies that are available as spare parts. Organon Teknika cannot supply any particular component for printed circuit boards or mechanical assemblies. Performing service to component level is not allowed and practically impossible in most cases, due to non availability of the required test fixtures, special adjustment tools and test software, used SMD technology and specific ESD safety conditions. Any attempt to perform other repair activities, than those explained in this manual, will void all warranty claims. In the case of complicated problems, which cannot be solved by exchanging available spare-parts, the complete module must be returned to Organon Teknika International.
INTRODUCTION
Only those modules, printed circuit boards and assemblies which have a trade-in number assigned to (refer to spare part list) must be returned for repair to the Instrument Repair & Assembly department at Organon Teknika International Turnhout. Other parts have to be disposed of locally. All parts returned should be provided with transport securities (if applicable) and packed in the original or by Organon Teknika approved packaging materials. The returned parts will be sent to the manufacturer for repair, fully automated testing and automatic failure investigation. These repaired parts are offered as trade-in parts with a reduced price to the NCs service organizations. A trade-in part has the same technical performance and quality as a new part but has been repaired. WARNING : Assembly, installation, extensions, re-adjustments, modifications, ana! repair are only to be carried out by persons authorized by Organon Teknika This authorization can only be obtained after a successfully completed, detailed technical service training course, organized by Otganon Teknika
1.2. UDdate of the manual To keep the information provided in this manual up to date, until a new edition appears, the service department of Organon Teknika uses a mailing system. All service organizations Teknika regularly receive authorized by Organon TECHNICAL NOTES. These technical notes supply the service organizations with technical information on all Organon Teknika equipment. You should always file these TNs in your service manuals. Technical notes can include: - Addenda to service manuals - Explanations of software updates - Modification instructions - Suggestions for use, adjustments, trouble shooting and modifications - Changes in the spare parts lists - Other technical Information If you do not receive these technical notes inform your technical department or your Organon Teknika representative or the International & Assembly department at Organon Teknika International Turnhout. 1.3. Status of the MPP 3000 unit A small DC0 label can be found on some sub-assemblies. This label indicates the actual rework status of that part and should never be removed ! The rear panel of the MPP 3000 contains an history box with service logging cards. service Repair
., ::
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INTRODUCTION
The serial numbers from the modules and dates of installation unit are listed on Registration Card I and II . The serial numbers from the boards and dates of installation are listed on Registration Card III . The software versions and dates of installation Registration Card IV . All preventive maintenance the Preventive Maintenance
in the MPP 3000
in the MPP 3000 unit
in the MPP 3000 unit are listed on
performed on the MPP 3000 unit must be notified logging card. on the MPP 3000 must be notified
on
Any service activity performed logging card.
on the Service
The information filed on the service cards must represent the real status of the unit. Additional service cards can be ordered when necessary (Art. code 08743). The service cards should never be removed, this to make the verification of the actual status and revision level of the MPP 3000 system easier.
INTRODUCTION
FOR YOUR
OWN
NOTES
I \. . . B
GENERAL DESCRIPTION
2. General descrhtion
The MPP 3000 is an automatic device for simultaneous and continual processing of microplates according to relevant diagnostic test descriptions. The total process executed by the MPP 3000 can include microplate incubation, washing, reagent dispensing, shaking and optical measurement.
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, /
. /
I I I
1 - PROCESSOR 2 - MPP-3000-m 3 - MONITOR 4 - KEYBOARD
TABLE
Fig.
2.1.
: MicroPlate
Processor
system
. _ __. ._ _ __-.-w----1--
GENERAL DESCRIPTION
2.1. Functional
descriotion
The MPP 3000 system incorporates three main functional modules : a central control system, a transport module and a chemical processing module (Fig. 2.2.). Each main module is divided into subdivision modules to fullfill specific tasks. This high level of modular approach makes the MPP 3000 transparent to service, although it is a complex system.
F1g.
2.2.
: MPP 3000
functional
block
diagram
GENERAL DESCRIPTION
2.1.1. Central control system All activities performed by the MPP 3000 are under control of a built-in 486 IBMcompatible computer. This computer contains a hard disk drive of at least 160 MB, at least 16MB RAM, a Bitbus Control board and an Ethernet board. The Bitbus Control board provides the communication between the computer and the other modules of the MPP 3000 system. The Ethernet board offers a connection to an external network system. The Unix multi-tasking Operating System and MPP 3000 application software are resident on the hard disk. The MPP 3000 has a built-in Un-interruptable Power Supply (UPS) available power the computer system temporarely in case of a mains power failure. 2.1.2. TransDort module to
Microplates for processing are placed into special carriers, which are entered into the MPP via the input module. A stack of up to six carriers can be entered. The transport system then picks up the carriers, one by one, and transfers them to one of the chemical processing modules. At the end of the test protocol, the carriers containing the microplates, are returned to the operator via the output module. The plate carriers are provided with an electronic label for positive identification during the entire process. For linking this electronic identification to the plate ID, known to the external systems, a barcode is attached, containing the same code as the electronic label. 2.1.3. Chemical Drocessing module The MPP 3000 contains nine incubator modules. The incubation temperature and time can be programmed individually for each incubator. Additionally three storage positions are present for ambient temperature incubations or temporary storage of a maximum of eleven plate carriers. The microplates can be washed by an eight channel washer module. At the front of the MPP 3000 there are three, individually content checked, washliquid containers available. At the rear an extra connection for an auxiliary (or large) washliquid container is provided. Two reagent dispense modules are available. Each module can handle up to six different reagents. Reagents are dispensed by a disposable pump system. Two fans keep the reagent storage area close to ambient temperature. The reader module is able to perform single or multiple wavelength readings, kinetic readings and scan readings. The filter tray can hold a maximum of eight interference filters. The 405nm, 450nm, 492nm, 540nm, 620nm and 690nm filters are present in a standard configuration. Refer to the operating features. manual for a more extensive description of the MPP 3000
GENERAL DESCRIPTION
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Fig.
2.3.
Instrument
modules
TECHNICAL
DESCRIPTION
3. Technical
description
The block diagram in Fig. 3.1. illustrates the modular approach of the MPP 3000.
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I el
Fig.3.1.
: Block
diagram
MPP 3000
_._ . ..~ _ -. ..._ . ..1_--_--. -_.---
TECHNICAL
DESCRIPTION
10
3.1. Hardware
overview
Five levels are created by the framework of the MPP. On each level specific modules are installed. Each level is also split into a front and rear section. The Input module, Output module and three container modules are mounted in the lowest level at the front. Three LEDs (mounted in the front panel at the left of the input module) display the system status. The green light indicates that power is applied to the system. The orange light is switched on when operator assistance is required and the red light indicates a fatal error condition. At the back section of the lowest level all power supply modules are installed : the UPS (Un-interruptable Power Supply), the +5V and + /-15V Power Supply and the +24V Power Supply. The front section of all other levels is occupied by the transport arm with grab. The transport arm moves in horizontal (Y) direction and the grab (mounted on the arm) moves in vertical (2) direction. The second level contains (from left to right) incubator module no.9, the reader module and washer module. The plate storage positions are provided at the front of the reader: respectively the left one can have 3, the middle one 2 and the right one 6 plate carriers stacked, respectively. In the third level the following modules are installed (from left to right) : incubator modules no. 5, 6, 7 and 8, and dispense module no. 2 (or the lower dispense module). The fourth level contains (from left to right) : incubator modules no. 1, 2, 3 and 4, and dispense module no. 1 (or the upper dispense module). Above these modules, on the upper level under the top cover, five internal controller boards are mounted in a metal box. These are the interfaces for the incubator modules, washer module, reader module and both dispense modules.
On the right side of the frame the two dispense reagent doors for the upper and
lower dispense modules are mounted. There are also boards mounted in a metal box at the right side of the frame behind the right cover : the internal controller board for the transport system, position control board, motor control board and label decoder board. The computer unit is mounted ,on a support plate with rubber shock absorbers, to the frame behind the left cover. 3.2. Detailed description of the modules of the individual MPP 3000 modules is given in
A short technical description following paragraphs.
TECHNICAL
DESCRIPTION
11
3.2.1. Power supplies

3.2.1.1. The UPS module The built-in UPS can provide a maximum of 15 minutes AC power to the
computer system.Only the computer systemwith monitor is kept powered during a

mains power interruption, not the MPP unit ! The operator must, in case of a power interruption, shut down the MPP main program and the Unix operating system within 10 minutes. This prevents damages to the MPP 3000 files or the Unix Operating System. The UPS is set for a specified mains voltage and frequency and can not be converted. The built in maintenance-free batteries are automatically charged when the MPP 3000 is switched on. A small fan circulates air through the module to cool it down during operation. Several audible signals are generated by the UPS to indicate its working status : - A short and long duration beep is generated during the power up initialization. - An intermittent short beep is generated, at 30 seconds interval, to indicate a mains power failure status (the UPS is using power from its built-in batteries). - A continuous beep is generated when the battery threshold limit is about to be reached (the UPS will shutdown soon). - An intermittent short beep is generated, at short intervals, to indicate overheating or a shutdown due to the reached threshold limit of the batteries. 3.2.1.2. The +5 Volt, +/-15 Volt Power Supply
This is a low power (160VA) multiple-output switching power supply. This module provides the + 5 Volt and + /-15 Volt DC voltage for the electronic circuits in the MPP 3000. The output specifications 3-15A + 5v +15 v 0.5 - 4 A - 15 v 0.5 - 2 A +24 V 0.5 - 2 A are as follows :
(this output is not used in the MPP 3000)
The module is mains frequency independent. The input voltage is selectable between 120 Volt and 220 Volt AC (the module must be dismantled to reach the selection wire). An input surge and over-voltage protection, as well as a primary and secondary over-current and short circuit protection are included. Only the +5 Volt output voltage is slightly adjustable. This module is not provided with forced cooling but is cooled in the MPP 3000 using the fan of the +24 Volt power supply.
TECHNICAL
DESCRIPTION
12
3.2.1.3. The +24 Volt Power Supply This high power (lOOOVA), single-output switching power supply, module provides nominal +24 Volt 40 A . The +24 Volt is used for all power appliances. Hence, all heating elements and cooling fans of the incubator modules, the reagent door cooling fans and all drive motors (DC and stepping) used in the MPP 3000 modules. The +24 Volt module is mains frequency independent, over-voltage and thermal protected and the input voltage is selectable between 120 Volt and 220 Volt AC. The module is cooled by a fan, the speed of that fan varies with the load on the 24 Volt output. 3.2.1.4. Power distribution No mains voltage is used in the MPP 3000 for the modules except for the UPS and computer. The mains is only present at the connector plate at the rear, the Power Supplies and the computer. The power supplies low output voltages are routed through the MPP 3000 via a set of vertical and horizontal busbars. Power supplies, modules and boards are connected to these busbars with colour coded wires. Ferrites are provided in some longer power cables to suppress high frequency noise induction and/or emission. Reference table of wiring colours for low voltage power connections : yellow = 0 Volt (ground) from +24 Volt power supply = +24 Volt red grey = -15 Volt black = 0 Volt (ground) from t 5 Volt + /-15Volt power supply = t5Volt orange = + 15 Volt white Refer to Fig. 3.la. for connections to busbars.
TECHNICAL
DESCRIPTION
Fig.3.la.
: Low
voltage
power
connections.
TECHNICAL
DESCRIPTION
14
3.2.2. Incubator
module
A functional breakdown of the module is shown in Fig 3.3. The incubator module contains two ceramic heating plates for warming up a microplate to a specified incubation temperature. This specified incubation temperature will be maintained until a specified incubation time has passed. The upper heating plate is motionless mounted in the module frame. The lower heating plate or carriage can slide out (in X direction) for loading of the plate carrier with microplate. Refer to Fig. 3.2. The carriage moves over two sliding bars and is driven by a stepping motor using a toothed belt. The carriage is driven to home position while initializing. The load position for the plate carrier is set under software control. The loaded microplate is completely enclosed by both heating plates when in closed position. This to maintain a uniform temperature over the microplate and to prevent heat losses. When the incubation is finished and the microplate is removed then the carriage is driven to the cool position. The built-in fans (two in each incubator module) then draw air through the slightly opened heating plates for a forced cooling down of this incubator module. This software controlled cooling down phase lasts for 10 minutes. The sensor interconnection board, the small board mounted in the front section of the module, contains two opto-interuptors for carriage position sensing. The front one is the max out-sensor and the back one is the home sensor. Refer to Fig.3.2. The ceramic heating plates are very well isolated from the environment and driven with +24 Volts. The temperatures of both heating plates are controlled and measured independently. In each heating plate an accurate temperature sensor and an overheating protection device (polyswitch, 1OOC) is integrated. The upper heater plate temperature will always be slightly higher (+O.SC) and the lower heater plate slightly lower (-OYC) than the current target temperature. In this way a controlled heating distribution is obtained with no significant evaporation of the liquid in the wells. The average value of both temperature sensors is displayed in the runtime screen, in the respective incubator module windows. On top of the module the incubator board is mounted, which is connected via the 37-pin connector to the incubator interface chain bus. The end of this chain must be terminated. The terminating resistor arrays are mounted in the incubator module 9. The incubator board contains the circuits for temperature measurement and control and the stepping motor driver. Each incubator module must have a unique address in the MPP 3000. This is done by setting the address jumpers on the board. The incubator module does not contain any software. All incubator modules interchangeable in the MPP 3000 except for the address setting and terminating resistors in the last incubator connected to the interface bus. The modules are fastened to the MPP 3000 rear frame with four screws. Only cable connections must be made : the power cable from the busbar and shielded bus cable. are the two the
TECHNICAL
DESCRIPTION
SPORT
PROTECTION
Fig.
3.2
: Incubator
module
II
I
INCUMT'ION STATION I I I HEATING /COOLING CONTROL Y
Fig.
3.3
: Block
diagram
Incubator
TECHNICAL
DESCRIPTION
16
3.2.3. Washer module

A functional breakdown of the module is shown in Figure 3.4. The washer module performs washing of microplates in the &way direction by aspirating all liquid out of each column of wells followed by refilling them with washliouid.
UASHER MOOULE I
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The fo;..x:;.:g jil;.t::icJr!t; are av:iil:~bit: in iixz washer module : the plate carriage driving system (X direction), the manifold drive assembly (2 direction), the vacuum pump, the dispense pump and the washliquid selection valves. Refer to Fig. 3.5. - Plate carriage driving system A stepping motor using toothed belts drives the carriage in X direction. The carriage is supported by a maintenance free linear bearing system. An opto-interrupter sensor (mounted in the center of the base frame) detects the carriage home position, using the long positioning strip glued underneath the carriage. From this home position the necessary steps are calculated to drive the carriage with microplate under the manifold to the correct positions. In the back there is an opto-interrupter which is a limit sensor (max-in) for the carriage drive system. In case the drive system is activated without carriage present (or if the home opto-interrupter is malfunctioning) then the signal of the max-in sensor reverses the driver direction to prevent blocking of the driving system. The max-out limit sensor is mounted on a small board at the front of the module. On this same board is also the LED for the manifold present indication. The carriage is provided with a priming cup and a gravity drainage to prevent liquid from entering the module by overfilling or other spillages.
Go to Table OF Contents .
TECHNICAL
DESCRIPTION
17
Remark : the carriage is fastened with a knurled screw to the driving system and can be removed from it for cleaning purposes. - Manifold drive system The manifold holder is driven down and up, by means of a DC motor with an excentric cam. The manifolds upper position is detected by a micro switch. An opto-interrupter and a leaf-spring loaded flag are used to detect the presence of a plate carrier in the carriage when in the down position. In the absence of a plate carrier (then the flag will not enter the opto-interrupter) no washing activity will be performed. The manifold assembly, with individual aspirate and dispense tips, is firmly locked to the manifold drive system with a knurled screw. Two opto-interrupters are mounted on top of the manifold drive system for sensing the presence and correct positioning of the manifold. The operator can remove the manifold for cleaning activities. If the manifold is missing, or not correctly installed, then a small red LED will be lit at the front of the module. The washfluid supply and vacuum connections of the manifold drive system is provided with O-rings to prevent leaking.
FJQ,
3.5
: Yasher
module
- Vacuum pump The vacuum pump, needed for the aspiration function, consists of a high speed DC motor with a centrifugal turbine disc mounted in a PVC housing. A vacuum detector monitors the presence of sufficient vacuum while aspirating. The aspirated fluid is drained into an external waste container with a slightly positive pressure. A fluid detector is mounted in the lower part of the pump housing. This sensor will detect the vacuum pump filling up with liquid, due to an obstruction in the drain system.
.._ -_..- .--- -- _-..
TECHNICAL
DESCRIPTION
18
The air outlet of the vacuum pump is provided with a two stage filter assembly for collection of aerosols. Fluid collected in the primary filter is sucked away by the vacuum pump. The outlet from the filter assembly contains an external filter sheet that can be replaced during maintenance. - Dispense pump A syringe pump, driven by a stepper motor, transfers an accurate amount of washfluid to the manifold dispense tips during the forward piston movement. Backwards movement of the piston will suck in the washfluid from the selected washfluid container into the pump. - Fluid selection valves The three built-in valves can connect up to four different wash liquids to the dispense pump. These four wash liquids are connected to the ports (1, 2, 3 and Aux) at the rear of the washer module.
. ?
- Washer boards The washer module contains 3 printed circuit boards : the washer control board, the washer power board and a small board for the geometry check. The washer module is connected with the internal controller board for the washer via the 37-pin connector on the washer control board. Local intelligence and software are available on the washer control board and the internal controller board The washer power board contains all power drivers for the motors and selection valves. The geometry sensor scans above the microplate to check if any of the strips in the microplate frame are elevated. Elevated strips can cause a jam against the manifold and/or the carriage transport system. The scanning sensor is connected to the geometry board. If the sensor is triggered by an incorrect height of the microplate then this plate will not enter the module. The hardware is already available in the module but not yet software supported. The washer module is fastened to the MPP 3000 rear frame with four screws, a power cable and two flat cables. The shielded bus cable and the cable from the container modules must be connected to the washer module. Also all tubes for the washfluids to the inlet ports must be attached.
_,: .
TECHNICAL
DESCRIPTION
19
3.2.4. Container
module
modules are installed at the front of the MPP 3000.
Three wash liquid container Refer to Fig. 3.6.
. Fig. 3.6 : Container module
All three container modules are interconnected with a small flat cable which is connected to the washer module. The washfluid from the containers is transported by a system of rigid pipes to the rear of the MPP 3000. From there it is connected to the washer inlet ports with silicon tubes. On a small board mounted at the rear of the container module, are located the address jumpers for the container coupling and liquid level detection. The last module connected to the bus cable has a terminating resistor array installed. An opto-interrupter monitors the correct coupling from the container to the module. The float assembly, mounted in each container to sense the liquid level, has a waterproof reed switch coupled with a moveable permanent magnet. Refer to Fig. 3.7. As soon the level in one of the wash fluid containers becomes too low (between 250ml and 300ml) the float interrupts the coupling between magnet and reed switch. The output signal from the float assembly is transferred through two contact plates mounted at the rear of the container, and a spring loaded receptacle assembly mounted in the housing of the container module. A mesh filter in the suction line of the filling plug prevents foreign particles or debris in the container from entering the dispense pump.
TECHNICAL
DESCRIPTION
Fig.
3.7.
: Float
rystm
In wurhliqutd
contalnar
TECHNICAL
DESCRIPTION
21
3.2.5. Dispense module

A functional breakdown of this module is shown in Fig. 3.8.
INTERFACE
Fig.
3.8.
: Block
diagram
of
dispense
module
The dispense module consists of two parts : a stationary module and a reagent door, refer to Fig. 3.9. and 3.12. Although they form one unit, both parts are mounted separately in the MPP 3000. The stationary module is mounted at the most right position on the third and fourth level in the MPP 3000 frame. The reagent door is attached with a hinge to the right frame plate of the MPP 3000. The stationary module contains the following functions : a carriage drive system, a pump selection system and a pump drive system. Refer to Fig. 3.10. and 3.11. - Plate carriage drive system A stepping motor drives the plate carriage using toothed belts in the X direction. The carriage is supported by a maintenance free linear bearing system. The carriage home sensor is mounted on a movable part, adjusted by the reagent door position. The home sensor is actuated by a flag on the carriage. In this way the exact position of the needles towards the centers of the wells can be calculated. The limit positions of the carriage are detected by opto-interrupter sensors. The opto-interrupter in the back is the limit sensor (max-in) for the carriage drive system. In case the drive system is activated without carriage present (or if the home opto-interrupter is malfunctioning) then the signal of the max-in sensor reverses the driver direction to prevent blocking of the driving system. The max-out opto-interrupter is mounted on a small board at the front of the module. The carriage has a priming cup and a gravity drainage to prevent liquid from entering the module by overfilling or other spillages. Go to Table OF Contents
TECHNICAL
DESCRIPTION
22
Note that the carriage is fastened with a knurled screw to the driving system and can be removed from it for cleaning purposes. This module does not contain geometry sensing. Some older modules still contain the hardware, but this is not operational.
- Pump selection system A stepping motor drives the pump selection system using toothed belts along the side of the reagent door. The system slides over two bars mounted in the module. The home sensor opto-interrupter for the pump selection system is mounted at the rear of the module. The pump selection system must be in home position to unlock the reagent door. It moves the stepping motor which drives the pump disposables in the reagent door. - Pump drive system The pump drive stepping motor moves a small slide up and down over two guide bars by means of a thin leaf spring. On this slide two ball bearings are mounted which will hold the paw1 of the selected pump in the reagent door. The home or down position of the pump drive system is also detected by an opto-interrupter
Fig.
3.9
: Dispense
module
TECHNICAL
DESCRIPTION
23
Fig.
3.10.
: Block
diagram
stationary
dispense
module
Two more opto-interrupter sensors are mounted in the stationary module : the reagent door lock sensor and the home sensor for the needle head drive of the reagent door. The dispense control board is mounted on top of the module. This board contains local intelligence and software and communicates via the 37-pin connector with the internal controller board for the dispense module. The board communicates with the reagent door and contains the circuits for the sensors and the power drivers for the stepping motors in the stationary module. 3.2.5.1. Dispense reagent door In the reagent door there are 6 locations for reagent containers and up to 6 disposable syringes can be installed. The door can easily be opened (only when the pump select motor is in home position) to obtain access for installation of the
pump disposablesand needles.

- Pump system The pawls at the back side of the reagent door are attached to the clips which hold the pistons of the pump disposables. The pump pistons are driven up and down by the pump drive stepping motor in the stationary module, refer to Fig. 3.13. The reagent door contains several sensors, refer to Fig.3.14. The presence of each disposable syringe is detected by a pair of scanning sensors. Each pump system slides up and down on two guide bars which are fixed in the door. The pump down position is detected by another pair of scanning sensors mounted inside the reagent door.
TECHNICAL
DESCRIPTION
24
- Needle head The needle head is driven by a stepping motor using a toothed belt. The needle head slides on two guide bars above the microplate in the Y direction. This needle head must be in the park position, detected by an opto-interrupter, before the reagent door can be opened completely. The needle head contains six holes in which the needles of the disposable syringes fit. The needles are kept in the correct position by spring loaded balls. Each needle is detected by a set of optical sensors. These sensors scan through the needle to detect the presence of liquid or air bubbles. The hardware is already in the module available but not yet software supported. All electronics in the reagent door is handled by the pump control board. The pump control board is mounted inside the reagent door and is connected with a flex cable to the control board in the stationary module.
Fig.
3.14
: Sensors
in
stationary
module
TECHNICAL
DESCRIPTION
Fig.
3.12.
: Dispense
reagent
door
./+-I ,'
,'
,'
,'
,'
Fig.
3.13
: Liquid
circuits
in
the
reagent
door
Go to Table OF ..-. Contents . --. -_-.
._. -. -_l_-__--
TECHNICAL
DESCRIPTION
26
liquid / b&A (ofhcal) sensMs needle Mock drive motoc fioq dwr /
0
Fig. 3.14. : Block
-- -------__
rwpt bottk r&(6 bottles) Dispense reagent door
-----
-- - E99
0
diagram
TECHNICAL
DESCRIPTION
27
3.2.6. Reader module

The reader module can perform end point readings, scan readings and kinetic readings. The module contains a carriage drive system, a filter tray drive system and optics to perform optical density measurements in microplates. Refer to Fig.3.16. -Carriage drive system A stepping motor drives the carriage by means of a thin steel cable. An optointerrupter sensor, mounted at the rear, detects the home position of the carriage. From this home position the necessary steps are calculated to drive the carriage to the load position and to determine the measurement points in the wells of the microplate. The max-out sensor is mounted at the front of the module. The geometry sensors scan above the microplate to check if any of the strips in the microplate frame are elevated. Elevated strips can cause a jam against the optical assembly. The scanning sensors (transmitter and receiver) are connected to the geometry board. If the sensors are triggered by the microplate, then this plate will not enter the module, but returns to the loading position. This function is operational and software supported. - Optical system The optical system contains nine light channels. Eight channels are used for column measurement in the microplate and the ninth channel is used to stabilize the light intensity. All channels are completely separated from each other. Each channel has a separate light source, lens system, filter and photodiode. The lamp block, which contains nine lamps, is cooled by a small fan. The speed of the fan varies with the temperature in the lamp block. The lamps are powered by an accurately regulating DC power supply. The lamps are switched on only during a microplate measurement. The light beams pass vertically from the top to the bottom, and are focussed at the bottom of the wells of the microplate. The interference filter is located between the bottom of the well and the photodiode. The light falling on the photodiode creates a current. This current is converted into a voltage and this voltage is read by an A/D convertor. Each well is scanned for 31 readings. The center readings are averaged and reported as the OD value for that well. The reader can measure from 0 to 3 OD. - Filter drive system The reader module can incorporate up to 8 different interference filters. These filters are installed on a tray which is driven by a stepping motor. An optointerrupter sensor detects the home position of the filter tray. The filter tray is accessible at the front of the module in eject mode. The filter positions and values are kept in Ram memory of the reader module, as well as the last measured values. A 45 Volt battery pack (a package of three Alkaline AA size 1,5 Volt batteries) is available for back-up of Ram memory. The main board contains local intelligence and software and communicates via the 37-pin connector with the internal controller board for the reader module. The board also contains the logic for the sensors and the power drivers for the stepping motors.
TECHNICAL
DESCRIPTION
.
Fig. t 3.15. **.. : Reader module .-
24V=
sv1 I I MML ET
CPU
-.
fig. 3.16. : Block diagram Reader
_----.
-.. - . ..-.. .-.-----.--
TECHNICAL
DESCRIPTION
29
3.2.7. Transport
system
The transport system takes care of the transportation of microplates between modules inside the MPP 3000 . It consists of a robotic arm assembly with grab, a position control board, a motor control board, the plate carrier label decoder, the plate input and output module and alert board. See functional decomposition in Fig. 3.17.
INT. TMNSPORT i IDENTIPICAT. (X11.2.3) I
WSITIONR
Fig.
3.17.
: Functional
decomposition
of
the
transport
system
3.2.7.1. Arm assembly The vertical arm of the transport system moves in Y-direction (left-right) and is driven by a DC motor with encoder. This motor is fastened on the right frame plate and drives by means of a toothed belt and a spindle. This spindle drives a bus with inside ball recirculation. A guiding block for the vertical arm is mounted on this bus and is guided by a sliding bar parallel with the spindle at the top. The base of the vertical arm is guided by a shaft fixed in the left and right frame of the MPP 3000 . Refer to Fig. 3.18. The vertical arm construction consist of two guiding shafts and a central spindle with a bus. Also this spindle drives a bus with inside ball recirculation and is driven by a DC motor with encoder using a toothed belt. The guiding block mounted on this bus can be driven in Z-direction (up-down). The grab assembly is mounted on this guiding block. Four Hall-effect sensors (one sensor for left and one for right are mounted on the arm guiding block, one sensor for up and one for down are mounted on the grab assembly) are provided for home initialization and for end of travel detections .
TECHNICAL
DESCRIPTION
30
The home position for the arm (Y) is at the right frame plate of the MPP 3000, the home position for the the grab (2) is at the upper vertical position. Four safety microswitches (one switch for left and one for right are mounted on the arm guiding block, one switch for up and one for down are mounted on the grab assembly) are provided to switch off the driver motors when the arm or grab moves out of control to its mechanical limits. Activation will directly switch the motors off. 3.2.7.2. Grab The grab assembly is mounted on the guiding block of the vertical arm shafts. It is able to pick up a plate and to release it elsewhere. It is provided with sensors for sensing the presence of a plate carrier and to make corrections in the Y (arm) and X (module carriage) direction. The feedback from the grab sensors is used for fine tuning the positions providing a self-learning feature. Furthermore the grab is able to read the special electronic label mounted in each plate carrier. (Refer to Fig. 3.19). The thumbs can be pressed up and this makes it possible, in combination with sensors, to feel if there is a plate carrier under or in the grab. The sensors are on the grab sensor board and the magnets are attached to the thumbs.
TECHNICAL
DESCRIPTION
31
Fig.
3.18.
: Transport
nodule
Fig.
3.19.
: Grab
TECHNICAL
DESCRIPTION
32
The fingers can be opened using two solenoids and are closed by two springs. The fingers must be opened to grab the plate carrier. The fingers hold the plate carrier while kept closed The position of the fingers is monitored with sensors on the grab sensor board via magnets displaced by the fingers. The fingers are hinged and connected to a suspension plate. The thumbs are connected with leaf springs to this suspension plate. The suspension plate is connected with leaf springs to the middle part. This middle part is then connected with leaf springs to a solid part. Therefore the suspension plate with the thumbs and fingers can move in Y and X direction. The sensors for the Y and X deflection are on the grab sensor board and the magnets are mounted on the solid part of the grab. A special damping is provided to damp the vibrations in Y and X directions. In the center part a small pin is mounted. The ends of this pin are placed in silicon cups and filled with silicon oil. The lower silicon cup is fiied on the suspension plate and damps the vibrations in X direction. The upper silicon cup, providing damping for the vibrations in Y direction, is fixed with a plate to the mounting plate of the grab 3.2.7.3. Plate carrier label decoding The grab control board contains the sensor (aerial) for the electronic plate carrier label. This aerial provides the electromagnetic coupling to power the identification circuit in the plate carrier. The aerial is connected to the label decoder processor board which is mounted in a metal box at the right frame plate. The output of the label decoder processor board is via RS232 transferred to the internal controller board for the transport system. 3.2.7.4. Plate Input/Output module
: \
.. :
Upon request, the plate input will move out a tray on which the operator can put a maximum stack of six plate carriers. In the plate input unit, an elevator will present the plate carriers with microplates one by one to the grab. The grab places the processed microplates one by one on the elevator of the plate
outputmodule.Also uponrequest, the outputmoduleejectsthis stackof plate

carriers. The plate input and output module are identical (Fig. 3.20). By setting a jumper on the board the module can be configured as input or output. The plate carriage of the module is driven out and in (X-movement) by a DC motor and a set of toothed belts (Fig. 3.21). On the left and right driving belt pins are fastened. The carriage plate sits on these pins. An opto- interrupter mounted at the rear of the module detects when the carriage plate is at home position and an opto-interrupter mounted at the front of the module detects when the plate carriage is completely out. The signals from these opto-interruptors are used to control the drive motor for the carriage.
TECHNICAL
DESCRIPTION
33
The carriage plate is guided at the sides and when it moves out it takes an extra support plate with it. The carriage plate and the extra support plate are connected via a magnetic coupling.
Fig.
3.20.
: Plate
I/O
module
TECHNICAL
DESCRIPTION
34
A stepping motor using a toothed belt drives the elevator system (Z-movement). An opto-interrupter mounted at the bottom of the module detects when the elevator is down in its home position. The elevator can only lift the carriage plate when it is at home position. The height of the stack, or amount of plate carriers loaded on the carriage, is sensed by a pair of scanning sensors mounted at the top of the module. Mounted at the rear of the module there is a control board. This board contains the logic and drivers for the motors and is connected via a 37-pin flat cable with the internal controller board for the transport system. The storage temperature sensor is connected to the output module board, while the alert board is connected with the input module. The input module is fastened with four screws at the left side of the front of the MPP 3000. The output module is mounted next to it. 3.2.7.5. Alert board The alert board is mounted inside the front panel at the left. It indicates the status of the MPP 3000 and drives the audible beeper in case of alarm conditions, to alert the operator. The volume of this beeper can be adjusted by a trimmer potentiometer on the board. The beeper can also be disabled by moving a jumper on the board to the OFF position. The alert board contains the relay for the alert outlet plug available at the connector plate at the rear of the MPP 3000. This relay provides one close and one open contact. The relay is activated together with the orange or red LEDs. 3.2.7.6. Transport system boards
The transport system uses the folowing boards : a position control board, with an RF1 filter board, a motor control board, a label decoder board and an internal controller board. These boards are mounted in a metal box at the right frame plate of the MPP 3000. Local intelligence and software are available on the interface board and motor positioning board. The motor positioning board and motor control board drives and controls the arm and grab movement, monitors the status of the sensors and the front sliding door switches. Fig. 3.22 shows the interconnections between the transport boards.
TECHNICAL
DESCRIPTION
35
_- -
-. -
2 B
.-
Fig.
3.22.
: Transport
boards
interconnections
. _~ -_.-._ _. . -.----~.__.
TECHNICAL
DESCRIPTION
36
,._ ..- _-_.-_ _ .-----
INSTALLATION
37
4. Installation
procedure
This chapter contains all information necessary for the installation of the MPP 3000. This includes site and power requirements, initial inspection, unpacking, removing transport securities, and a functional check. Unpacking and installing the system must only be carried out by qualified personnel. 4.1. Environmental reauirements The volume and weight of the MPP 3000 require some precautions to be taken. Certain aspects should be checked during a site inspection. Refer to the check-lists underneith. The instrument should not be installed near a heat source. While the MPP 3000 is operating the ambient temperature should not exceed 25C ! The cooling fans in the reagent bay are not able to cool down below ambient temperature. An ambient temperature higher than 25C can change the performance of some reagents which are stored for a long time in the MPP 3000. The MPP 3000 must be positioned away from direct sunlight or extremely bright light sources. This will avoid optical disturbance of processing microplates on the storage positions. 4.2. Power reauirements The MPP 3000 is factory defined for the voltage and mains frequency which is indicated on the label at the rear. The MPP 3000 contains components which are voltage and frequency specific. Rewiring for other than the indicated voltage or frequency is not possible ! Check that the specifications on the label match the local mains provisions. The 220V 50Hz version is fused with 8A and consumes about 6.5A. The 120V 60Hz version is fused with 15A and consumes about 12A. 4.3. Incomine Inspxtion
The MPP 3000 has been thoroughly inspected and tested before being shipped and should be in good operating condition. Upon receipt, carefully inspect the instrument and its accessories for any physical damage sustained in transit. If the Microplate Processor is received in a damaged state, immediately file a claim with the carrier, save all packing material and notify the nearest Organon Teknika sales office. If items or accessories are missing, please contact the nearest Organon Teknika representative. 4.4. Pre-installation check-lists
The following check-lists can be copied and then used for site inspections prior to installation of a MMP-3000 at the customers location - Standard laboratory operating environment requirements - System delivery/installation requirements - Pre-installation site inspection of MPP 3000
INSTALLATION
STANDARD
LABORATORY
SYSTEM MPP 3000 OPERATING ENVIRONMENT
REQUIREMENTS
Environmental requirements: Ambtent tern nature: 1. - operating 1r thru 2SC - nonoperating -10 thru 43C, when drained. 2. Relative humidity: - operating 20% thru 90% (non condensing) - nonoperating 5% thru 95% (non condensing) Heat dissipation: approximately 1500 W idling. of system instrumentation:
3.
Location 1.
lights. The instrument The instrument must be Tp sitioned away from direct sunlight and areas with bright overhead should not be placed tn t e dtrect path of air draft. heater or air conditioner vents or doors that could cause strong temperature fluctuations. A single line phone (modem). must be within 8 meters (2.15feet) of computer system for remote access capability to be utilized \ : : _ -
2. 3.
The Customer must certif that the floor structure where the MPP xxx) is to be installed is capable of bearing a of an MPP 3000 on a bench is required, the Customer must certify weight of about SO0 kg (l&3 Ibs) Ifplacement that both the bench and the supportmg floor structure are capable of bearing a weight of about SO0 kg (1000 Ibs). The MicroPlate Processor in most cases, shall be installed on its table. For the screen and keyboard provided and can be mounted on (preferably) the left- or right hand side of the table. The maximum are: width (inclusive height (in total) depth tray) 820 mm (33 inch) the customer must allow the e ui ment to be maneuvered lo a position that will allow a clearance of 1 meter (39 inches 3p o any service panel and top of equipment. a tray is dimensions
4.
5.
To maintain setviceability, minimum of unobstructed requirements: A properly grounded outlet
Electrical 1. 2. 3.
AC power
circuit
capable about
of providing
8 A at 220-24OV
(15 A at 12OV) to the MPP 3000. instrument. as a
The AC power
must be within
1.2 meter
(4 feet) of the installed
To ensure roper operation of the MicroPlate Processor, the supporting electrical circuit must be maintained dedicated P ower Source (i.e. not setvicing large power consuming devices) and free from excessive voltage disturbances and high frequency noise. requirements:
Modem 1.
2.
The MODEM will operate line and/or PSFN). orotection: for earthquake
using the same type of phone
lines as that are used for a FAX-machine
(2/4
wire leased
Earthquake Requirements
protection
must be specified
at the time of order
(applies
only to USA).
INSTALLATION
CUSTOMER SURVEY FOR SYSTEM MPP 3000~ SYSTEM DELIVERY/INSTALLATION REQUIREMENTS

1. A specific customer contact must be desi nated by name and phone number to coordinate with Organott Teknika Field Engneer will t-e uest thts for the delivery/installation of the MPP f&xl system . Organon Teknikas information during the site inspection visit. The following additonal information wtll be require 3 from the customer contact during the site inspection a) What Comments: b) Are deliver there any customer established or local code restrictions to the customers receiving dock? on the size or type of transport vehicle that can are the days/hours of operation of the customers receiving dock?
2.
The customers receiving dock and the internal delivery route behveen the receiving designated for system installation must meet the following physical requirements: a) The unloading area and all portions of the internal following external dimensions of the MPP packaging. %8t(mind turn areas) weight support Comments: delivery route (including
dock and the location
elevator)
must take into account
the
b) After un eking the MPP 3000 will be placed on its table. For the screen and keyboard.a tray is provided be mounte 8 on (preferably) the left or right hand side of the table. The maxtmum dimenstons are: !%?(mind the turn areas) weight support The table rollers are delivered internal delivery route should Comments: i surface of the receiving
and can
on 7.6 cm (3 inch) diameter casters. The floor not restrict the movement via these casters.
dock and the
. _. -....-_-.--.-
INSTALLATION
CHECKLIST FOR OT-REPRESENTATIVE PRE-INSTALLATION SITE INSPECTION
FOR A OF MPP 3000
[] [] [] (1 [] []
SATISFACTORY ACITON REQUIRED SATISFACTORY ACTION ACTION REQUIRED REOUIRED
Temperature Comments: Room relative
range : 15C to 25C
humidity:
20% to %
Comments: Location of system isntrumcntation: must be positioned should away from direct sunlight and areas with bright 1. The instrument overhead Comments: 2. A single line phone access modem Comments: 3. Customer 3OCKlsystem Comments: 4. The MicroPlate the keyboard Comments: 5. To maintain position service servicability. the customer must allow the equipment to be maneuvered (39 inch) of any to a Processor in most cases shall be installed and can be mounted on its table. For he screen and the left or right hand certifies that the the floor is capable structure, and benchtop a weight if utilized, of where the MPP capability must be within to be utilized. 8 meters (25 feet) fo computer system for remote
SATISFACTORY
lights. The instrument
not be placed
in the direct
path of air draft.
is to be installed
of supporting
3.50 kg (772 Ibs).
a tray is provided
on (preferably)
side of the table.
that will allow a minumum panel and top of equipment. requirements: grounded AC power
unobstructed
clearance
of 1 meter
Comments: [] [J SATISFACTORY ACTION REQUIRED Electrical
1. A properly 120V) Comments:
circuit
capable
of providing
8 A at 220-24OV
(1SA at
to the MPP 3000.
2. The AC power Comments: 3. To ensure devices
outlet
must be within of the MPP Power
1.2 meter
(4 feet) of the instrument
installed.
proper
operation as dedicated
3000 system,
the supporting water
electrical baths,
circuit Consuming
must be maintained including, refrigerators, free from Comments: [] [] SATISFACTORY ACTION REQUIRED Modem requirements: 1. A single phone must be within phone freezers excessive
Source
(i.e. not servicing air conditioners, significant
large power
but not limited
to, centrifuges, that radiate
or any devices
electromagnetic noise.
energy)
and
voltage
disturbances
and high frequency
line with a wall jack capable (2.5 feet) from
of accepting
a RlllC
type of connector capabilities. of The
8 meter
the MPP system
for MODEM
line for the MODEM one of the following
must be voice grade. analog. standards: BELL103.
signal type. capable
supporting Comments:
V21 or VU.
2. The MODEM machine Comments: [] [] SATISFACTORY ACTION REQUIRED acknowledgement: that Organon Teknikas Representative Earthquake If required Comments: Customer I certify
will operate
using the same type of phone PSTN).
line as that is used for a FAX-
(2/4 wire leased line and/or
protection Earthquake
(applies Protection
only for US): has to be engineered.
has reviewed
the findings
of this MPP 3000 Site inspection/installation by mail as to the impact these
with
me. I understand deficiencies Customer Customer
that if any deliciences
are noted during coverage
installation.
I will be notified
may have upon the warranty Signature Facility Name
of this MPP 3OW system.
Title State Date
OT Representative
.._~ . .I ..__--1-
INSTALLATION
41
4.5. Contents
of the sales Dackage :
The sales package is delivered in three packages. The MPP 3000 unit is packed in a big carton box strapped on a pallet. The monitor is packed in a single box and all other sales items are packed together in a separate box. 00167 The following Sales package MPP 3000 Version 220V / 50Hz items are packed with the MPP 3000 unit in the big carton box: 07399 : processor table 07412 : set of 10 filter sheets Washer 03921 : 4m of silicon tubing 12x8 08467 : Flacon ACCU lube oil 08207 : box of 10 fuses 8A 5x20 08463 : alert out plug 08359 : SC0 UNIX Open Desktop software 07236 : MPP 3000 Control software 07624 : Operating manual UNIX installation checklist Accessories and manual Ethernet board
The EVGA 15 colour display, 08480, is delivered in its dedicated box The following items are packed together in a separate box : 06956 : workstation keyboard UK 08255 : Mouse 08281 : Barcode scanner 08205 : 2 sets of standard plate carriers (20 PCS) 08466 : set of dispense pump disposables (60 PCS) 07398 : Liquid container 80257 : kit of reagent containers 50ml(180 PCS)with accessories 80258 : kit of reagent containers 1OOml (108 PCS)with accessories 80259 : kit of reagent containers 200ml (56 PCS)with accessories 08515 : Cleaning tool incubator (10 PCS) 00168 The following Sales package MPP 3000 Version 120V / 60Hz items are packed with the MPP 3000 unit in the big box: 07399 07412 03921 08467 08208 08463 08359 07236 07624 : processor table : set of 10 filter sheets Washer : 4m of silicon tubing 12x8 : Flacon ACCU lube oil : box of 10 fuses 15A 6.4x32 : alert out plug : SC0 UNIX Open Desktop software : MPP 3000 Control software : Operating manual UNIX installation manual Accessories and manual Ethernet board
The EVGA 15 colour display, 08480, is delivered in its dedicated box Go to Table OF Contents
INSTALLATION
42
The following
items are packed together in a separate box : 07175 : workstation keyboard US 08255 : Mouse 08281 : Barcode scanner 08205 : 2 sets of standard plate carriers (20 PCS) 08466 : set of dispense pump disposables (60 PCS) 07398 : Liquid container 80257 : kit of reagent containers 5Oml(l80 PCS)with accessories 80258 : kit of reagent containers 1OOml (108 PCS)with accessories 80259 : kit of reagent containers 200ml(56 pcs) with accessories 08515 : Cleaning tool incubator (10 PCS)
4.6. Hardware
installation
The unpacking procedure and removal of the transport protections are depicted step-by-step in the following pages. First unpack and install the MPP 3000 unit on its table, refer to figures 4.1. through 4.16. Then remove all transport protections and make all necessary connections, refer to figures 4.17 through 4.24. While proceeding with the installation, the service engineer should inspect the internal wiring and connectors for loose connections. All packing materials and transport protections should be retained for later usage in case the MPP 3000 or parts must be shipped to another location. 4.6.1. Reauired tools Following appliances and tools are recommended for easy handling instrument during installation : Pallet wagon or fork truck Crane, advised type WK-1000 manufactured by Kaisser & Kraft Lifting tool or hoisting bracket 08191 Set of standard metric handtools Phillips screwdrivers no. 1, no.2 Set of metric socket wrenches Open-ended spanner no.8, no.13, no.17, or an adjustable spanner of the
INSTALLATION
43
Fig.4.1.
: Remove
both
outer
bandages.
Fig.4.2.
: Remove
top
of
package.
INSTALLATION
44
--
__---
,.
a--
Fig.4.3.
: Remove
shock
absorbers.
Fig.4.4.
: Lift
off
outer
sleeve.
INSTALLATION
.. .
- -. __
.. .
-.
Fig.4.5.
: Lift
off
the
processor
table
(two
persons
required).
Fig.4.6.
: Remove
all
items
stored
between
shock
absorbers.
Remove
bandages.
INSTALLATION
46
Fig.4.7.
: Remove
shock
absorbers
and
protective
sleeve.
Fig.4.8.
:.
Remove
protective
carton
cover.
INSTALLATION
47
Fig.4.9. MPP 3000
: Unscrew the six with an open-ended
bolts which fasten spanner no.14.
the
table
tray
to
the
subframe
of
ttm
/ /////\ / I / / / / / /<*.-1 /
/ 7
Fig.4.10. : Unlock the 4 screws which hold the lift the panel from the MPP 3000, then disconnect 9.2.1. for specific details. backpanel with the ground
/ /
a Phillips wire. Refer
screwdriver, to paragraph
..__I .._ ___-___l_-...~--
INSTALLATION
48
Fig.4.11.
: Remove
the
top
cover.
Refer
to
paragraph
9.2.2.
for
specific
details.
rlg.4.12.
: Mount
the
4 bolts
for
the
hoisting
bracket
onto
the
MPP 3000
frame
INSTALLATION
__
Fig.4.13. bracket : Lift the MPP 3000 from the table tray, using a crew and the hoisting
Fig.4.14. slit for
: Place the drain
the MPP 3000 in tubings matches.
the center of the processor Remove the hoisting bracket
table. and
the
verify that 4 bolts.
the
__ _. _ __ ____ --. ....^_ .-I--
INSTALLATION
50
Fig.4.15.
: Mount
the
tray
on the
left
side
of
the
processor
table.
Fig.4.16. : Unpack the monitor the MPP 3000. Connect barcode,
and keyboard, scanner and
put mouse
them on the to MPP 3000.
tray
and
connect
both
to
_-.-gl .
INSTALLATION
51
When the table with the MPP 3000 is at its final location then the feet can be mounted. The table can then be adjusted to the floor, if needed. The instrument has to be leveled because of the liquid handling. 4.7. TransDort Drotections
Before removing the transport protections from the MPP 3000, it is recommended to transfer the total system to its final destination. Basically all transport protection can be removed in an arbitrary order.
Fig.4.17.
: Transport
protection
Grab
and
Positioner
The grab is tied to the shafts of the positioner with tye wraps or cable ties. Cut the tye wraps and remove the buffer foam block on top of the grab. The positioner also is tied with tye wraps on the top of the left frame. Cut the tye wraps and remove the buffer foam block. Take care not to scratch or damage the shafts.
INSTALLATION
blg.4.18. is fastened
: Transport with tape
protection Plate on the carriage.
Input
and
Output.
The
Hexagonal
spanner
(3m)
Fig.4.19.
: Transpori
protection
of
Incubator
modules.
--. __- _-
~__--
INSTALLATION
53
Fig.4.20. unlocking
: Transport the 2 screws.
protection
Washer
module
(front)
Support
the
anrambly
while
Fig.4.21. before
: Transport removing.
protection
Washer
module
(rear).
Slide
the
bracket
to
the
left
INSTALLATION
54
;.
Fig.4.22.
: lnrtrllrtlon
of nunifold
in Washer module.
Lock with
th
knurled
knob.
Fig.4.23. reader block.
: Transport protection in the frame Carefully Remount and fasten the
Reader module. Remove the 6 screws which fasten slide out the module until you can remove the module in it's original position.
the foam
Go to Table -OF Contents
INSTALLATION
Fig.4.24.
: Transport
protections
in
Dispense
module.
Remove
all
foam
blocks.
Put the tube couplers in the slot of the table and lengthen the 4 drain tubings with the provided silicon tubing. Put the endings in a vented waste container below the table. Note that draining of waste materials occurs by gravity. Remount the top cover and rear panel, take care not to pinch any tubing or cables. Check all electrical connections prior to connecting power to the instrument. To check the correct performance of the MPP 3000, it is recommended to run all calibration procedures. 4.8. ReDackinp instructions NOTE : Before packing and shipping the MPP 3000, the instrument must be thoroughly disinfected according to the disinfection procedure explained in this manual. The fact that the instrument has been disinfected must be stated on a disinfection form sent with the instrument or attached to the outer packaging. This form has to be signed by the responsible authorities, Instruments without a disinfection form will be refused. Basically, the repacking procedure has to be executed in the opposite order as the unpacking and installation instructions as depicted before. Proceed as follows : Provide all transport protections. Then build up the pallet....
._ .,.. -._l__l^l_
INSTALLATION
56
Fig.4.25.
: Build
up of
the
pallet
Remove the tray from processor table and place it upside down on the pallet. Remove top and back panel from the MPP 3000 and install all transport protections. Lift the instrument from the table, using the special lifting tool and a crane, and put it on the tray in the pallet. Attach the MPP 3000 with the six bolts to the tray. Provide the shock absorbers in the middle of the instrument. Position the protective sleeve and put the absorbers at the edges. Provide ties around the instrument and the tray below it. Use the positions of the wooden bars for that purpose. Put operating manual, software packages, mains interconnection cable and eventually the tubing on top of the MPP 3000 unit. Lift the processor table over the instrument on the pallet. Put the outer sleeve over it and provide the shock absorbers at the edges of the table as in the pictures Install the top of the package and secure the package by means of ties.
._ -._ -. __^
INSTALLATION
57
4.9. MPP control software installation
or uDdate
The system is delivered with the UNIX operating system and the MPP-3000 application software already loaded on the hard drive of the computer. When a software update or re-installation is necessary then act according following procedure or follow the instructions which are provided with the update or installation diskettes. Precondition: Preconditions of the application software on the system: (this is very important at the penalty of loosing your user-defined protocols) AI1 reagents and washing fluids must be removed. None should be scheduled. Check this in the reagent handler and washfluids handler menus. No plates should be scheduled. No results files should be present. There should be no plates present.
The MPP-3000 software is provided on a set of three 3,5 high density diskettes. - Remove the left side panel (refer to par. 9.2.4. A). - Turn on the MPP unit and then the monitor, UNIX will boot automatically. until the login prompt is displayed. - switch to console 1 by pressing [CTR] + [ALTj + fl when the SCO-ODT displayed. - Login as root: type root < enter >. Wait
screen is
- At the password prompt type Rsnyyxxx <enter > where yy represents the year of manufacturing and xxx the serial number of the MPP unit. This number is displayed above the login prompt. - The root prompt # should now appear. - Type cd usr/tmp <enter >.
- Place disk-l in drive A. - Type tar xvp <enter>. - Follow on screen the directions for placing disk-2 and disk-3 into the disk drive. - Two files are created in the tmp directory : mpp - arch.Z and mpp - install. - When the # prompt returns type csh mpp install - When the # prompt returns type exit <enter >. Go to Table OF Contents
.._ _..~_ ._.- -_--
<enter>.
INSTALLATION
58
- Remove disk-3 from drive A. The MPP-3000 application - Re-install the left side panel (refer to par. 9.2.4. B).
software is now loaded.
- Bitbus driver installation: Necessary for first installation OR reinstallation. . user = root . type cd /usr/mpp/OBITBUS < return > . type ./linstall < re t urn> ( OR ./lreinstall <return> ) The kernel will be relinked, and the system will shut down. Remark: If there was a hard disk initialisation, restore following files from a floppy disk: -ACT.all(- > /usr/mpp/IM/config/ACT.all) -Protocols backup(files in /usr/mpp/OM/exe/backup). See intro of 4.10(UNIX installation) Login as root and type cd /usr/mpp/IM/config <enter > Insert the previously prepared floppy with ACT.all on it. Type tar xvp ACT.all <return > Type I <enter > The contents of the config directory is displayed. It should contain the file ACT.all now. The next step is to copy the protocols database on the new harddisk. Insert the floppy with the protocols which was prepared above in the drive and Type cd /usr/mpp/OM/exe/backup <enter > Type tar xvp < enter > c enter > Type uncompress protocols.tar.2 Type tar xvfp protocols.tar This restores the files in /backup. If NO backup, then the protocols are lost. IR&A departement may have the original(production
made) ACT.all file.
INSTALLATION
59
4.10. UNIX installation
on the hard drive
This installation procedure is only necessary when the computer has been replaced or when a new hard disk is installed or if UNIX becomes damaged. If possible following files should be saved from the damaged disk: a) Save ACT-all file on floppy Switch the MPP on and login on terminal 3 as root(press and hold[ALT] and press [F31)Type cd /usr/mpp/IM/config <enter > Insert one formatted floppy in the drive and copy the ACT.all file to this floppy by typing tar cvp ACT.all c return > Type tar t <enter > to check the proper performance of the previous operation: ACT.all should be displayed as the contents of the floppy. Remove the floppy, mark this floppy with ACT and make it read-only. b) Save protocols on floppy The protocols and security files are back-up-ed with a text like protocols type cd /usr/mpp/OM/exe/backup <enter > on one floppy. Mark this floppy
Type tar -cvfp protocols.tar *.* <enter > ( this combines all files in the backup directory into one archive-file, called protocols.tar) Type compress protocols.tar c enter > Insert one furmatted, but empty floppy in the drive. Type tar -cvp protoco1s.tar.Z < enter > Check the contents of the floppy: type tar t <enter > The contents of the floppy is displayed: it should contain the file protoco1s.tar.Z Remove the floppy, mark this flopy with protocols and make it read-only! c) Save network configuration and filesystem mount.
The network configuration as it is established within the present UNIX version 1.1 must be saved for installation on the new UNIX version 3.0 operating system. Insert formatted, butempty floppy in the drive and proceed as follows: Type cd /etc < enter > Type tar cvp hosts <enter > (this saves the hosts file on floppy) Type cp tcp tcp.old <enter > (this makes a copy of the tcp file for later reference) Type tar rvp tcp.old <enter > (save tcp.old on floppy) Type cd /etc/default c enter > Type cp filesys filesys.old <enter > Type tar rvp /etc/default/lilesys.old c enter > Check the contents of the floppy: type tar t <enter >. A list should be displayed which contains the files hosts, tcp.old and filesys.old. Remove the floppy, mark this flopy with network and make it read-only!
INSTALLATION
60
4.10.1. Hard disk initialisation SC0 UNIX 3.0 only.
4.10.1.1 PREPARATION The Open initialisation. Desktop installation starts with a preparation and hard disk
UNIX installation is executed by filling presented while installing UNIX.
data in an installation
menu which
is
The data must be taken from the check-list(4.10.1.13). This check-list is completed first as follows: Serial number of PC Copy the serial number from the serial number plate of the PC. Serial numbers and activation keys
Take the colored cards and write down clearly the serial number (letters and numbers) and activation key (only letters) belonging to each part of the installation.( NCR ODT and SC0 Open Desktop International Supplement) on the installation check-list. System name Enter the system name chosen for your machine (sn..... completed serial number. Example: sn92021. Use lower case letters!!) IP address The interface IP address is determined as follows: IP address :: = 192.121.123.cAA~ <AA> ::= <sequential number > + 4 <sequential number > is equal to the serial number of the MPP abbreviated by leaving the manufacturing year part away and leaving any leading zeros away. Example: <sequential number> of the MPP with serial number 92021 is 25 Passwords. Three passwords have to be chosen. One for the super-user (root) , one for nuucp user and one for the service user. The password for the root is Rsn ..... (in which ..... is the unit serial number of the MPP: example: Rsn9202 1) The password for the service user is Ssn..... (in which ..... is the unit serial number of the MPP: example: Ssn92021) The password for the nuucp user is Nsn..... (in which ..... is the unit serial number of the MPP: example: Nsn92021) with machine
INSTALLATION
61
4.10.1.2 UNIX installation UNIX is supplied on sets of floppy disks. Insert floppy marked Nl into the drive. Switch the computer on. Press <enter > as soon as the text SC0 UNIX System V/386 Boot: is displayed. Insert floppy marked N2 when prompted. Insert floppy Nl when prompted. From here you enter Set-up. A series of screens is displayed asking for information about the system. Follow the instructions on the screens using the information on the installation check-list. When you have specified the correct configuration for the system, select Proceed with Installation from Set-up to proceed. Insert floppy Ml when prompted and press <enter >. Insert appropriate floppys as you are prompted. This will take some time. You are prompted to assign the root password. Follow the instructions on the screen to select your (own) password. This Dassword is very important. If no one remembers this password. then you have to reinstall the whole svstem. You are prompted to insert the SC0 Open Desktop/SC0 Open Server Release 3.0 release Supplement. Follow the instructions on the screen to install the supplement. The operating system is rebuild now. This will take some time. The system shuts down. remove the floppy from the drive when you see the Safe to power off message and press <enter >.
INSTALLATION
62
-? : ::
4.10.1.3 Creation of users. Press <enter > when you see the Boot: prompt. When you see the INIT: SINGLE USER MODE message, enter the root password to bring the system up in system maintenance mode (single user) With the procedure below three different users are created. These are: - mPP - service - ldm Perform the procedure for each user individually. Also the password of user nuucp is changed in this section. Login as root Type sysadmsh <return > Select Accounts Select User Select Create Enter user name (either mpp or service or ldm: use lowercase letters only!) < return > ) Enter comment (either mpp user or service user or Idm user < return > ) Modify defaults? enter y < return > A new window is displayed now. Login group: select Specify (type s or move highlight with cursors and press < return > when highlighted) Enter mpp < return > The first time you create the users on a MPP this group is not known by the system yet. It must be created first now. In this case a new window pops up. Proceed as follows: Group does not exist ....... Do you wish to create it? enter y < return > Group ID: select Specify (type s or move highlight with cursors and press <return > when highlighted) and enter value 100 <return > Now you return to the previous window
c-3
. -_--_ .._ .._. -... ~--.--ll
INSTALLATION
63
A window like the one displayed below appears: kwUP mPP
El Type c return > until the window disappears again. Login shell: select Specify (type s or move highlight with cursors and press <return> when highlighted) Press F3 and move highlight to the line csh (normally it will be there alreadys). Press <return > . Home directory: select Default (type d or move highlight with cursors and press <return> when highlighted) Select Create Home < return > User ID number: select Specify (type s or move highlight with cursors and press <return> when highlighted) and enter value 202 for user mpp or 203 for user service or 224 for ldm user < return > Type of user: select Default (type d or move highlight with cursors and press <return> when highlighted) Choose Yes from the next window (type y or move highlight with cursors and press < return > when highlighted) Press <return > to continue with either a or b below:
INSTALLATION
64
a. If you are installing the mpp user then select Remove from the window (type r or move highlight with cursors and press < return > when highlighted)
b. If you are installing the service user or the ldm user then select Now from the window (type n or move highlight with cursors and ress ~return> when high P ighted) Change at first login: select No (type n or move highlight with cursors and ress c return > when highlighted ; . Pick your own password (type 1 and press < return > ) Enter new password. For the service user this password is Ssn...... in which .... stands for the sn number of the MPP involved: example Ssn92021. For the ldm user: password is passwd. Re-type the password. Press Creturn >.
Now select Examine, to modify the password of the nuucp user. For Username fill in nuucp < return > . Type P. Use the arrow keys to go down to the line Current password status. Select Change, and type < return > . Change at first login: select No (type n or move highlight with cursors and press < return > when highlighted). Pick your own password (type 1 and press < return > ). Enter new password. For the nuucp user this password is Nsn ....... where ..... stands for the serial number of the MPP. You may either create an other user (see list at the start of this paragraph) or leave the sysadmsh utility by pressing [F2]and y to leave. Check: While logged in as root, type cd <return >, then I <return >. The root directory is shown on the screen. The list should contain a line which should read: drwxrwxr-x .. root ..........usr auth If the character combination drwxrwxr-x is not correct, then type chmod 775 usr <enter > . If the owner is other than root, then type chown root usr <return> If the group is other than auth, then type chgrp auth usr < return >.
INSTALLATION
65
4.10.1.4 Setting system parameters. While logged in as root, type sysadmsh, select System, select Configuration, select Kernel, select Parameters. TvDe 4 to select from the menu. Scroll through the options with <return> (reply y on override recommended options each time this message is displayed) Change NPROC to 200 by entering that value. Change MAXUP to 150 by entering that value Change NREGION to 600 by entering that value Select 5 when the menu appears again. Change NCALL to 200 by entering that value Select 7 when the menu appears again. Change MSGMAX to 8192 by entering that value Change MSGMNB to 24576 by entering that value Change MSGTQL to 100 by entering that value Change MSGSSZ to 32 by entering that value. When the menu appears again then type q followed by y on the appropriate questions. Select Rebuild from the Kernel menu. The kernel will be rebuilt. This will take a while. The question to use this kernel by default is replied with y and y is replied to rebuild the kernel environment once more. Leave sysadmsh by typing F2 y Type shutdown -g8 -i8 -y <enter > when the rebuild is finished: the system will come down and the computer can be switched off when the allowance for this appears on the screen or the system can be booted again by pressing any key.
INSTALLATION
66
4.10.1.5 Unix default files modifications Login as root. cd /etc/default < return > Type vi tar < return > This file must be edited as follows:
The line
archive = /dev/rfd0135ds9 must be edited to: archive = /dev/rfd0135ds18 Leave the vi editor by typing type vi format Center > The line device = rfd0135ds9 should be edited to device = rfdO135ds 18. Leave the.vi editor by typing 4.10.1.6 Autoboot settings 18
720
1440 n 18 :wq <return >
:wq <return>
Type sysadmsh c return > Select SYSTEM, CONFIG, DEFAULT, OTHER. Press F3 end select BOOT from the list, < return > < return > By this action a file is shown in the vi editor, which must be changed as follows: Move the cursor to the line with the text FSCKFIX = YES press i; type TIMEOUT= 20 < return > [escape]. This adds a new line in the file which is saved now by typing :wq Return to the main menu with [F2] followed by y. Type init 2. In this way you return to the normal login screen. You may either shutdown login as root to continue with the next paragraph.
or
. ^ .._..- . ..... .. -.._. .__ I __.___^ I -_____ - -_-_.--
67
4.10.1.7. Time and date adjustment. After having logged in as root, type asktime <return> and adjust the clock as required. (for instructions about this adjustment: type man asktime c return >. This invokes the on-screen manual page which explains the date command. Leave the manual page by pressing DEL.) Example of date and time setting: date 04080920 i.e. April (04) day of month (08) hour (09) minutes (20) 4.10.1.8. DHR floppy preparation Login as root. 4.10.1.8.1 UNIX formatted floppy preparation.
Mark a floppy (1.44 MB) with UNIX files and insert it in the floppy drive. type format <return > Follow the instructions on the screen. Write the MPP3000 serial number on the floppy and keep the floppy with the MPP check-list. 4.10.1.8.2 DOS formatted floppy preparation
Type DOS <return> The DOS prompt C: > appears. Mark a floppy (1.44 MB) with DOS files and insert it in the drive and type format a: < return > Proceed the formatting routine; reply n <return > to the question do you wish to format another ..... Type quit <return > to leave the DOS emulator. Write the MPP-3000 serial number on the floppys and keep the floppy with the check-list.
INSTALLATION
68 / <
4.10.1.9 Check of network functionality The proper operation of the network installation is checked as follows: Connect the computer ethernet card with the OT coaxial network. Type: ping 192.121.123.01 <return > With this command a continuous flow of messages is send to the ESU UNIX network server and echoed back by the server. Terminate the command after a few minutes by pressing the DEL key. The result of the test is reported on the screen: a loss of packages of 0% must be reported. 4.10.1.10 Configuration 4.10.1.10.1 Configuration of ports of second serial port
Login as root. Type mkdev serial < return > Choose i (install a new serial board) Select 1 port card Select COM2 Select IBM-COM Type speed: 9600 <return > Select 1 from next menu Reply n to relink the system 4.10.1.106 Configuration of parallel port
Type mkdev parallel c return > Choose 1 (add a parallel port) Select 1 ( Serial/Parallel adapter #1 : address = 37837f ) type <return > ( default interrupt 7 ) Reply y to relink the system
, 9:
. . ----_--_ --. ._ l_-ll_..---..--
INSTALLATION
69
4.10.1.11 Prepare for mount
Login as root. Type cd /etc < return > Type vi exports < return > Hit the [ESC] key and type / Hit the [ESC] key again and savethe file, type :wq c return > Type chgrp other exports c return > , type chown root exports
c return >
.._._ ___ ..^.,_ -...-. .__-. -_l_-..--.--
70 ._
4.10.1.12 Modem installation Login as root. Type cd /usr/lib/uucp < return > Type vi Dialers < return > Type /# Hayes Smartmodem 2400 < return > The cursor is now at the beginning of: # Hayes Smartmodem 2400 # hayes = ,-, I ATQOEOT&D2&ClSO = 043\r\c OK\r ATDT\T\r\c Speed # # and afterwards reinitialise to dialin mode # OK\r ATEO&D2&ClX4S2 = 128 OK\r &hayes2400 = ,-, I + + + \dATQOH ATSO = lQl\r Type ma Go with cursor down until the empty line under &hayes24OO...ATSO = lQl\r Type ya Go one line up ( above line # Hayes Smartmodem 2400 ) Type P Now the part concerning Hayes2400 modem is copied. In the second part every occurrence of 2400 should be changed into 9600. Go with cursor to second line with # Hayes Smartmodem 2400 Type 12400 Type cw!%OO< ESC > Type n Type cw9600 < ESC > Type n Type CW?%OOC ESC > Use the arrow keys to return to the line: = 043\r\c OK\r ATDT\T\r\c Speed hayes = ,-, ATQOEOT&D2&ClSO Use the arrow keys to go to SO=O, to the 0 after the = Type Rl Close the file by typing :wq Type uuinstall c return > Type 3 <return >
Type2 <return>
For each line a default setting is shown. Change the default setting as follows: Fill in : Device type : ACU <return > Fill in : Tty line : tty2A < return > Fill in : Dialer line : - <return > Fill in : Speed range : 9600 <return > Fill in : Dialer : hayes c return > Fill in : Switch token : \D c return > Fill in : Dialer : < return > To check whether everything is filled in as expected, type 1 <return > When ok, type q< return > When message appears :Changes have ... Write to fiie(y/n)?, type y < return > Type 4 c return > Type 2 c return >
------_-
-.-__- ..- -
INSTALLATION
71
The tty-setup appears now. Fill in: Line ? tty2A Mode ? m Then appears : Login : will be enabled Type q <return > Type 5 <return > Now the files will be checked for consistency, type y An overview of the checked files will appear. If there is an error message, call EPT/sw. Type c return > Type q <return > Remark: To allow copy permissions from the remote station adapted: /usr/lib/uucp/Permissions Add following part: MACHINE = OTHER LOGNAME = nuucp \ COMMANDS =rmail:rnews:uucp:ls:who:pwd \ READ = /usr/spool/uucppublic:/usr/tmp:/tmp \ \ WRITE = /usr/spool/uucppublic:/usr/tmp:/tmp NOREAD = /etc \ SENDFILES = yes REQUEST =yes
following
file should be
INSTALLATION
72
4.10.1.13 Installation
changes. the change of the installed network card
The instructions below describes parameters and the system name. 4.10.1.13.1. Change of network installation.
You should be logged in as root. No other users should be logged in. Type mkdev wdn <return> and type d <return > to delete the configuration which is present. The root cursor appears again. Type mkdev wdn <return> again and type i < return > to start the installation of the new driver parameters. Follow the menu and reply y to relink the kernel. After relink of the kernel, type vi /etc/hosts < return > Remove all lines in this file except the line which contains the text string localhost (preceded by a digit combination) (note: to delete a line, place the cursor on the beginning of the line and type dd) save the file by typing :wq Type mkdev netconfig < return>. The installation of the network address proceeds as follows: The interface IP address is the one in the installation check-list: 192.121.123... in which .. stands for the next available IP address on the OT network. This number is determined as follows: IP address :: = 192.121.123.<AA> <AA> ::= <sequential number > + 4 <sequential number > is equal to the serial number of the MPP abbreviated by leaving the manufacturing year part away and leaving any leading zeros away. Example: <sequential number > of the MPP with serial number 92021 is 25 You answer n on the broadcast address prompt and then you select the default broadcast address 192.121.123.255 with <return>. Also the default netmask 255.255.255.0 can be taken with < return > . Type q < return > to leave mkdev tcp Type cd \etc < return > Type vi hosts <return > Edit this file until it reads: localhost 127.0.0.1 192.121.123.~~ snyynnn snyynnn.OT.MED in which 192.121.123.~~ is the IP-address of the instrument
and snyynnn is the
systemname.
Save the changed file by entering :wq < return > Reboot the system by typing init 6 <return >
INSTALLATION
73
Remarks: a)If you have another network, then the IP address will be different! This means that /etc/hosts and /etc/tcp will NOT contain 192.121.123. as the IP address, but something else. Look at other systems in that network to find out this IP address. b)It is also possible that some mounts are locally added to the MPP working in a different network, then file /etc/defaults/filesys was adapted too(other mounts)! Example: Update file: /etc/default/filesys Use vi editor, and login as root. A mount from the MPP3000 to a host directory(LDM). = = > insert(i) with the vi editor: bdev = host:/LDMdir cdev = \ mountdir = /MPPdir mount =yes fstyp = NFS \ fsck = no fsckflags = \ desc=The host ldm directory \ remount =yes rcfsk = no mountflags = remark: If a mount from the OD data files = = > MPPdir: default = /usr/mpp/ldm/data as in the environment variable in /usr/mpp/.login ($LDM-DATA). Network restore with heln of the ~~ODDV disk: Put the floppy with the hosts file and other network related files in the drive. Type cd /etc <enter> Type tar xvp hosts tcp.old /etc/default/filesys.old <enter> (this puts the files hosts, tcp.old and filesys.old in the correct directory) In the etc directory there already exists a file called tcp. This file must be edited with values which you can look-up in tcp.old. Type vi tcp.old <enter>. Find the part of this file which is preceded with the comment: # interface configuration - - edit as appropriate This comment is followed by a line which reads: ifconfig wdn0 xxxxxxx -trailers netmask yyyyyyy broadcast ZZZZZZZ. Write down the values which are found on the places xxxxxx (= netaddress), yyyyy (= netmask) and zzzzzz (= broadcast address) Leave the tcp.old file by typing :q <enter > and proceed with vi tcp <enter> Find the part of this file which is preceded with the comment: # interface configuration - - edit as appropriate You see again a line as in the tcp.old file. Edit the values of the netaddress, netmask and broadcast address to the values noted from the tcp.old file. Save the file by typing :wq c enter > This ends the network configuration adjustment. The actual network installation, links and mounts may require other modifications which depend of the local situation. This may for instance mean a modification of the file /etc/default/filesys.
INSTALLATION
74
Compare the available file on the new disk with the transferred file /etc/default/filesys.old which is copied on the floppy and which is now in the same directory.
75
4.10.1.13.2 Change of system name Proceed as follows: (In the rocedure below the o& system name is indicated with 0 e DNAME and the new system name by NEWNAME) Login as root. No other users should be logged in. Type sysadmsh < return > Select System, Configuration, Kernel, Parameters and select 10 from the menu. Enter the new system name, followed by < return > . Type q <return >. Reply with y <return> on the question do you want to update..... Press any key to continue and leave sysadmsh with as many times [esc] as required and Quit. Type cd /usr/mmdf < return > vi mmdftailor < return > <return> (this replaces OLDNAME by type :%s/OLDNAME/NEWNAME/g NEWNAME in this file) Press [esc] key. Save the changed file by typing :wq < return > Type cd table <return > vi local.chn <return > type :%s/OLDNAME/NEWNAME/g < return > (this replaces OLDNAME by NEWNAME alover in this file) Press [esc] key. Save the changed file by typing :wq < return> Type vi mmdfdbm.dat <return > type :%s/OLDNAME/NEWNAME/g < return > (this replaces OLDNAME by NEWNAME alover in this file) Press [esc] key. Save the changed file by typing :w! < return >, followed by :q <return > Type vi root.dom < return > type :%s/OLDNAME/NEWNAME/g < return > (this replaces OLDNAME by NEWNAME alover in this file) Press [esc] key. Save the changed file by typing :wq < return >
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76
Type ./dbmbuild <return > Note: it has been noticed that this command sometimes responds with something like: memory failure: core dumped If this happens, you should type rm core <return>, then restart the system by typing init 1 <return>, then login as root and repeat the command ./dbmbuild and type cd /usr/mmdf/table <return> <return > . It should work now! Type uname -S NEWNAME <return > installed again. must be parameters network the Now Follow the instructions in chapter 3.1 Change of Network Installation. 4.10.1.13.3 Change of MIMS environment variable.
If MIMS version > = 3.20 Rel l:MIMS may detect tagged plates -- > setenv MPP TAG LMU FILES YES If MIMS version< 3.23 Rel lor MIMS NOT used NO -- > setenv MPP - TAG-LMU-FILES Proceed as follows: Type cd /usr/mpp <enter > Type vi Jogin <enter > Go to the end of the file with [SHIFT] + G Go to the end of the last line of the file with the cursor keys. Type a to enter the append mode. Now make a choice between a) or b) a)Type: setenv MPP-TAG-LMU-FILES NO OR b)Type: setenv MPP-TAG-LMU-FILES YES Press [ESC] Type :wq < enter >
____-_ --_ ._-. .._I_-_--.-_-.-.._II_-
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77
4.10.1.13.4 Printer Installation. It is possible to connect a printer to the MPP. This can be done with the aid of the One is a printer tool sysadmsh. Two examples will be given of a printer. connected to the parallel port, the other is connected via a tcp/ip network. 1) Configuring a printer
In the text below it is assumed that the available printer is a HPDeskJet printer. Adapt this assumption to the printer type you wish to install. Both the principals of installation of a printer on the PCs parallel port and on a connected network is explained.
a) Parallel port - log in as root - type in sysadmsh < return > - Select printer, configure, add A form appears which needs to be filled in as follows: printername : comment : classname : Use printer interface : Name of the interface : HPLaserJet ( make up your own name ) whatever comment you like ( leave blank ) Existing select the printer to connect from the list via < F3 > Direct /dev/lpO leave blank hard wired no
Connection : Device name : Dial-up information : Device : require banner : - Now select Default - With c F3 > make the just created printer the default printer Exit sysadmsh with [F2] and continue with c) Activate the printer.
b) Network
printer
- log in as root - type in sysadmsh < return > - Select printer, configure, add A form appears which needs to be filled in as follows: printername : comment : classname : Use printer interface : Name of the interface : Go to Table OF Contents HPLaserJet ( make up your own name ) whatever comment you like ( leave blank ) Existing select network from the list
INSTALLATION
78
via <F3 > Direct Connection : /dev/null Device name : leave blank Dial-up information : hard wired Device : no require banner : - Now select Default - With < F3 > make the just created printer the default printer Now exit sysadmsh with F2 and <enter> on the YES prompt. A file should be created in the directory /usr/spool/lp The file is called remote.: Type cd /usr/spool/lp < enter >
Type vi remote <enter > Type i (to enter the insert mode) Type: HPDeskJet: /usr/spool/lp/bin/rlpcmd Press [ESC] Type :wq <enter> Type chown lp remote <enter > Type chgrp Ip remote <enter > Type chmod 444 remote < enter >
ottusl
Ip -dHPDeskJet
Type 1: the list of files should contain a line with (amongst more): -r--r--r-- lp lp remote In the System Administrators 2) Activate the printer Now the printer accessible. is configured. But to access the printer, it should be made Guide Chapter 7 a different set-up is described.
- enter sysadmsh - Select Printers, Schedule - Start the print service by selecting start. This will probably result in a message that the printer service is already running. - Then select Accept. With the aid of < F3 > select the just installed printer to accept print jobs. - Select Enable. With the aid of < F3 > select the just installed printer to enable printing. - Exit sysadmsh with F2 followed by <enter> on the YES prompt.
3) Tips and tricks
INSTALLATION
79
Now the printer is ready to be used. But you will see that a banner will appear anyhow while printing. The banner can be disabled by editing the file /etc/default/lpd The line BANNERS = 1 should be changed in BANNERS = 0.
It is also possible that after every file which is printed, an empty page will appear. This can be solved by going to the directory: /usr/spool/lp/admins/lp/interfaces In this directory a file is present with the name equal to the printer name created. At the end of the file there is a line with : echo \033E\c. If you place # in front of that line, the empty page will not appear anymore while printing.
INSTALLATION
80
,, ? . q :
4.10.1.14 Unix Installation
checklist.
Unix Installation
(copy of page 23,24 and 25 of manual Installing Serial number of PC: 1. Boot-time loadable drivers required?
checklist
SC0 Open Desktop/SC0 ............. NO British ............. ............. Overwrite. sn...... OT.MED Middle European Not used in this time zone Traditional DOS services Online documentation Network Open Server
2. Keyboard type: 3. Serial Number: 4. Activation 5. Installation key: type:
6. System name: 7. Domain name: 8. Time zone: 9. Daylight savings: 10. Security level: 11. Optional components:
12. Configured 13. Mouse type:
for floppy disk drive Serial mouse e: Microsoft i? OMl Cirrus Logic GD542X VGA 1024 x 768 x 256 colors 60 Hz non-interlaced other 14 WD 8003 Elite series
14. video card: 15. Video mode: 16. Video monitor: 17. Network card:
:I<- 3 k4
I_ _... _--.---.--
INSTALLATION
81
Card type: Interrupt Vector (IRQ)
WD 8003 Elite 10 300 Not applicable Not applicable cc000 16 Not Applicable Not applicable Not applicable 192.121.123. 255.255.255.0 192.121.123.255 0 (default 0 (default) 0 30 Mbyte None = > 240 Mbyte)
Base I/O address ROM address DMA Base RAM address Ram size Local Ring Broadcast Slot Number cable type 18. IP address 19. Network mask
20. Broadcast address 21. DOS partition 22. UNIX partition size size
23. Other partition 24. Root filesystem size 25. /u filesystem 26. Swap space size 27. Other filesystems Root password: Service password:
. .__ .-. ..-. -_-,_ ~.._-_.. _--_-
82
CALIBRATION
83
5. Introduction
to calibration
Calibration of the MPP 3000 is necessary after installation of the system or replacement of the grab, the transport system or a processing module. The mechanical calibration of the modules is explained in Chapter 9: Replacement Instructions. The following service programs are available for calibration of the grab sensors and for setting the coordinates of the transport system and the module positions : - TptCal : used for calibration of the grab sensors, refer to par. 5.1 . - calposal : used for calibration of the coordinates of all modules and storage positions, refer to par. 5.2 . - calibpos : used for calibration of the coordinates of a single selected module or storage position, refer to par. 5.3 . Acknowledge each action performed by pressing the <enter > key . The instructions and messages displayed on screen are printed in bold on following pages . The service programs update all coordinates, for the transport system and the modules, which are stored in files inside ACT.all . This ACT.all is in directory usr/mpp/IM/config . NOTE problem a) Copy Go to Enter : In case ACT.all is damaged or becomes unusable, then correct the using one of the following procedures : from the usr/mpp/IM/config directory the file default.all to ACT.all . the directory usr/mpp/IM/config . : cp default.all ACT.all .
5.1. Grab calibration Be sure that the mechanical parallelism of the grab is correctly set. The mechanical grab calibration procedure is explained in chapter replacement instructions (refer to par. 9.4.3, B.). The TptCal program only updates the grab sensor values in the .tpt file inside ACT.all . 51.1. Preparation :
- Be sure that the MPP 3000 application software is not running ! If still running then quit the main program using End Operations and Shutdown . - Boot the system and at the login prompt simultaneously press the ALT and F2 key to activate another console. - Login as : service . (example Ssn92026) , - Enter password : Ssnyyxxx where yy is the year of assembly and xxx the serial number of the unit. This number is also displayed above the login prompt.
CALIBRATION
84
- Enter : cd positions . - Enter : $MPP IM/exe/DrvLoadShm . - Verify that no errors are displayed during loading of the shared memory. If so then shutdown and start over again. 5.1.2. Description of the procedure : and/or messages displayed on the screen.
- Enter : TptCal . Now follow the instructions
CALIB GRAB SENSORS : Start Be sure the grab is not in front of the READER/DISPENSE/WASHER The grab should be, for your own convenience, positioned somewhere in the centre of the MPP 3000 unit . No plate carrier in grab The grab should be empty. Verify that there is no plate carrier in the grab before pressing the center> key ! The grab fingers are momentarily opened after pressing the <enter > key . Insert normal plate into grab Insert gently a standard plate carrier with a microplate <enter > key when done .
into the grab and press the
Insert CAL plate carrier into grab for MAX thumb Gently push and hold the plate carrier in the grab fully upwards <enter > key is pressed .
while
the
Insert CAL for X-front Gently pull and hold the plate carrier in the grab as far as possible to the front while the <enter > key is pressed . Insert CAL for X-back Gently push and hold the plate carrier in the grab as far as possible to the back while the < enter > key is pressed . Insert CAL for Y-lefi Gently pull and hold the plate carrier in the grab as far as possible to the left while the <enter > key is pressed . Insert CAL for Y-right Gently pull and hold the plate carrier in the grab as far as possible to the right while the -Center > key is pressed . The list of calibrated sensor values is now displayed and must be examined before continuing . The values printed in this example may differ from the values displayed by the MPP 3000 you are working on .
85
Example of a listing : leftnoplt leftwthplt leftend rightnoplt rightwthplt rightend grleftcls grleftopen grrightcls grrightopen dfltxnorm dfltxfront dfltxback dfltynorm dfltyright dfl tyleft bf, 191 100,256 lal, 417 bO,l76 109,265 lb6,438 242,578 lOe, 270 lba, 442 23,163 4d, 77 fe, 254 ffffffffcb, -53 b2,178 149,329 ffffffffa5, -91 (left thumb without plate) (left thumb with plate) (left thumb max up) (right thumb without plate) (right thumb with plate) (right thumb max up) (left finger closed) (left finger opened) (right finger closed) (right finger opened) (balanced X defection) (max X defection front) (max X deflection back) (balanced Y deflection) (max Y deflection right) (max Y deflection left)
The sensor values are displayed in a Hex and Decimal notation. Verify that : - no sensor values should be equal to 0 , - the left and right thumb values show an increasing order, - finger opened value < finger closed value , - the values for the deflections are different . If an error occurred and the sensor values are not correct then press the <del> key and start again with TptCal . When the values are OK then press the <enter > key to continue . Remove plate carrier Remove gently the plate carrier from the grab and press the <enter> done. The calibration
key when
values are now only stored in memory and must be saved to the
.tpt file (insideACTall) on the harddisk.

- Enter : $MPP-lM/exe/DrvSaveShm . - Verify that no errors are displayed during saving of the shared memory. 5.2. Calibration of module Dositions
The calposal calibration program uses 6 plate carriers and will try on all module positions to put down a plate carrier and to pick it up again. The appropriate coordinate values are updated in the module files inside ACT.all . The execution of this program can be cancelled at any time by pressing the <del> key, but calibrations performed so far are lost in that case.
CALIBRATION
86
52.1. Preparation Preparation
: is identical to that explained in par. 5.1.1.
NOTE 1 : Be sure that the arm and grab parallelism has been correctly set and that the grab sensors have been calibrated (refer to par. 5.1) . NOTE 2 : When a reader, washer or dispense module has been replaced then the MSCARRDIST value of that module must be set to 0 (zero). This is to prevent of the new module. The correct value for errors during initialization MSCARRDIST (distance between home and max-out sensor) will automatically be filled-in after a successful initialization of the module. Use following procedure to modify the MSCARRDIST value : - Enter : cd /usr/mpp/lM/config . - Enter : vi ACT.all . - Move the cursor (using PgDn, PgUp and the arrow keys) under the numeric value for MSCARRDIST of the replaced module. - Enter : dw (to delete the current value). - Enter : i (to activate insert mode). - Enter : 0 (to enter the value zero) . - Press : [ESC]-key (to return to control mode). - Enter : :x (to save and quit the editor). - Enter : cd (to return to the service directory). - Enter : cd positions (to go into the positions directory). NOTE 3 : When an incubator module has been replaced then the module carriage must have been set parallel with the grab (refer to replacement instructions par. 9.3.1. B.) . 5.2.2. Description of the procedure :
- Enter : calposal . Now follow the instructions and/or messages displayed on the screen. Acknowledge or answer each instruction by pressing the <enter> key . While proceeding with the program you will get questions regarding each module/location to be calibrated . Answering N to a question skips that step and brings you to the next step. You can always try to skip a position correction with N, unless it is clearly visible that adjustment is required. A Retry Y/N option is offered after each program step that could not be executed successfully . NOTE : The program can become locked by entering a wrong input or by pressing the <enter > key (without first entering an answer as a reply to a question) . Unlock the program by entering ! and try to continue or restart calposal .
CALIBRATION
87
The instructions and messages displayed on screen are printed in bold on following pages . BE SURE ALL MODULES ARE CLOSED !! GRABBER NOT IN FRONT OF A WASHER/READER/DISPENSE !! The grab should not be in front of one of these modules. This is to eliminate the risk of hitting a module carriage and damaging the grab while the module is initializing . CALIBRATION MODULE POSITIONS program will be started MPP init will be started All MPP 3000 modules will now initialize and move to home position (except for the transport system) . Place 6 plate+carriers at the INPUT module The input module has opened and you must place a stack of 6 plate carriers . Transport INIT ? <Y/N > Always answer <Y > to this question ! First the grab and then the transport will move to home position for initialization. Skip calibration < module name > ? Y/N Normally < N > is entered . Enter only <Y > when you are sure that the calibration is not required . arm
of that requested module
Do you want to change the grab position ? Y/N This refers to the approach positions (Y and Z) of the grab to that module. The grab first moves quickly to this approach position and then starts the real putdown or pickup action . The Z approach position should be at such level that the module carriage, loaded with a plate carrier, remains free from the plate carrier held by the grab . Adjustment is required if the distance between the underside of the plate carrier in the grab and the top of the module carriage (frame or position pins) is less than 2mm or more than 15mm. (except above the input or output module) . If adjustment is required answer this question with <Y>. This allows you to change the Y (left-right) and Z (approach) position of the grab .
You can always try with <N>, unlessit is clearly visible that adjustmentis
required. If a program step could not be executed successfully then a Retry Y/N option is offered . UP), Won), WW, R(W) or No) Press the <u > (for up) or <d > (for down) key to change the grab Z approach position . Enter < I> (for left) or < r > (for right) to change the grab Y approach position. The construction of the grab allows about lmm of misalignment for an automatic correction .
CALIBRATION
88
Repeat this until the position of the grab looks correct and stop by entering c n > to continue with the next program step . Do you want to change the module position (x-direction=carrier) ? Y/N This refers to the X (in-out) position of the module carriage. The plate carrier in the grab may not touch module elements while it goes down. If the module carriage position seems correct answer the question with < N > or if adjustment is required answer with <Y > . I(n), O(ut) steps of about 0.5 mm or N(o) By entering <i > (for in) or CO > (for out) you can change the module carriage position in steps of approximately 0.5mm . Repeat this until the module carriage position looks correct and stop by entering < n > to continue with the program . Do you want to change the putdown-position ? Y/N In general you can enter < N > . The grab will lower until the plate carrier is placed and the program proceeds. If the grab can not execute this step, then the following message will be displayed : Retry ? Y/N . Replying with <Y > brings you back to the change putdown question . Enter cd> (for down) if the plate carrier did not reach the putdown position, or enter <u> (for up) if the plate carrier pressed firmly onto the module carriage . Repeat this until the putdown action is performed correctly and the program continues. Do you want to change the pickup-position ? Y/N Similar questions, but now related to the pickup sequence, will be repeated . At the end of a successful plate carrier pickup action a new and important question is asked : Is the GRAB + PLATE free ? (No plate + grab in the module) Y/N Verify that the grab with plate carrier is sufficiently cleared from the module . By entering <Y >, the module carriage will close immediately . To prevent any damage, you should enter <N> when the grab with plate carrier is still inside the module . In that case, the program automatically quits and restarts. (Height above storage pins : .....mm) While the program proceeds following question will appear several times : save auto positioning ? Y/N Normally always <Y > is entered. By entering Y the file with calibration values is updated in memory. The calibration program is finished when all plate carriers are back in the input module. Quit the program by pressing the -Cde1 > key . The calibration values are now only stored in memory and must be saved to the module files inside ACT.all on the hard disk . - Enter : $MPP-lM/exe/DrvSaveShm . - Verify that no errors are displayed during saving of the shared memory _ (By editing ACT.all file) .
CALIBRATION
89
5.3. Sirwle module uosition calibration The calibpos program allows the possibility calibration . 5.3.1. Preparation : of selecting one module at a time for
Preparation is identical to that explained in par. 5.1.1. Regard also the important notes in par. 52.1. ! The instructions pages . 5.3.2. Description and messages displayed on screen are printed in bold on following
of the procedure :
- Enter : calibpos . A list of selectable modules is displayed : Test of module : 0 = Incubator 1 = Reader 2 = Washer 3 = Dispense 4 = Storage 1 5 = Storage 2 6 = Storage 3 7 = output 8 = Input GIVE MODULE ID ? (O-S) : Enter the selection number for the module you want to calibrate . CALIBPOS program will be started at the INPUT-module
Place plate+carrier(s)
Sending data to transport Transport INIT ? c Y/N > Always answer <Y > to this question ! First the grab and then the transport will move to home position for initialization . The procedure arm
and questions are identical to those explained under calposal .
NOTE : the plate input or output and storage modules may contain more than one plate carrier. Calibrating plate carrier position levels higher than one (1) requires that the module under test must be pre-loaded with enough plates . When finished with calibration quit the program by pressing the < de1 > key .
CALIBRATION
90
The calibration values are now only stored in memory and must be saved to the module files inside ACT.all on the hard disk . - Enter : $MPP-IM/exe/DrvSaveShm . - Verify that no errors are displayed during saving of the shared memory . 5.4. Some useful Unix commands Because Unix is case sensitive, type the commands and parameters exactly as printed (take care for spaces and punctuations) followed by pressing the <enter > key . Unix command : cd cd / cd .. PWd 1 ps -ef I more I grep purpose : return to users home directory return to system root return one directory shows the full pathname of the current directory lists directories and files in the current directory reports active processes displays long lists by page when used with 1 or ps -ef creates a selected list, where xxx are the first letters of the string on which you want to select
Detailed information on Unix commands (and the Unix operating system) can be found in the Unix manuals delivered with the MPP 3000 system or use the online manual pages . man <command > displays information on the use of the command (and press the <enter> key to view the subsequent pages). 5.4.1. Using the vi editor for viewing and editing files : vi <file name> activates the Unix vi editor in the command mode
moving the cursor : use the left- right- up- down-arrow keys for cursor movements G moves the cursor to the end of the file moves the cursor to the first line of the file 1G searching for text : /string searches forward for the first occurrence of the given string n to repeat the forward search ?string searches backward for the first occurrence of the given string N to repeat the backward search
CALIBRATION
91
inserting text : i a
0
0 <beep > <esc>
switches to the insert mode, text can be entered to the left of the current cursor position switches to the append mode, text can be entered to the right of the current cursor position inserts a new line below the cursor position inserts a new line above the cursor position a beep indicates that the vi editor terminated the insert mode pressing the < esc> key terminates the insert mode and returns the editor to the command mode, typing an insert command activates again the input mode to replace a character above the cursor position to change a word after the cursor position
chanainp text : r cw deletinp text : dw dd . deletes the word to the right of the cursor deletes the current line
reneat and undo : repeat last command undo last command ttr restores the original content of the current line saving and leaving vi : :x or :wq or ZZ save changes and quit the editor quit the editor, works only if no changes have been made to the 4 file :q! forces to quit the editor without saving the changes
There are a lot more editor commands and functions available. Refer for detailed information to the Unix manuals delivered with the MPP 3000 system. 5.5. Unix shutdown Drocedure When finished, using the calibration and/or test programs or whenever working with the MPP 3000 must be interrupted, then following procedure should be performed to shutdown the Unix operating system in a neat way : NEVER SWITCH SHUTDOWN ! OFF THE MPP 3000 WITHOUT PERFORMING
CALIBRATION
92
- Logout on all open consoles by entering exit . - Simultaneously press the ALT and Fl key . - Login as : root . - Enter the password : Rsnyyxxx (example Rsn92026) , where yy is the year of assembly and xxx the serial number of the MPP 3000 you are working on, this number is also displayed above the login prompt. - Enter : shutdown 40 -gO -y (0 stands for zero and not the capital 0) . - Wait now until the following message is displayed : Safe to power off or Press a key to reboot Note : This may take several minutes . The MPP 3000 may now be switched off safely.
TROUBLESHOOTING
93
6. Introduction
to Troubleshooting
In the application program some menu selections are available for functional verification and troubleshooting of the MPP 3000 . QC-Check : In this menu the operator or technician can select a single module, or all modules, for a basic functional verification using a special diagnostic kit . The diagnostic kit contains dyes and temperature sensitive liquids for testing the processing modules (i.e. incubator, dispenser, washer) . For the verification of the reader a special reference plate (Field Test Plate) is needed . The test plates, wash liquids and reagents are automatically scheduled after selecting the module(s) for testing. Refer to the Operating Manual for detailed explanations . Autocalibration : This function is disabled in release 1.1 This program is almost identical to cycletst, refer to par. 6.2 . Service : No service programs are available in the main menu of software release 1.0 . Troubleshootingcan only be performed by using the BBM (Bitbus Monitor) as a diagnostic tool (see paragraph 6.5) and by checking the available logging files for error messages. Other test programs :
The following service programs are available for testing purposes :
- cyclemod : a cyclic dry duration test to check the error free functionality of the transport system with the module positions, refer to par. 6.1. - cycletst : a cyclic wet duration test to check the error free functionality of the MPP 3000. This program is almost identical to Autocalibration, refer to par. 6.2. - modtest : a QC program to check essential functional properties of the MPP 3000, refer to par. 6.3. - BBM : to diagnose a module by sending single commands using the Bitbus Monitor . The instructions listed are a guide for troubleshooting the basic functions of the different modules, refer to par. 6.5.
TROUBLESHOOTING
6.1. Positions duration
test
The cyclemod program will normally run continuously until an error condition appears, or until the < de1> key is pressed. No washing or dispensing will be done, only a short incubation and shaking in reader, dispense and washer module is done. The plate carriers are moved from module to module, using them all at least once.
6.1.1. Preparation :
- Be sure that the MPP 3000 application software is not running ! If still running then quit the main program using End Operations and Shutdown. - Boot the system and at the login prompt simultaneously press the ALT and F2 key to activate another console . - Login as : service . (example Ssn92026) , - Enter password : Ssnyyxxx where yy is the year of assembly and xxx the serial number of the unit; this number is also displayed above the login prompt . - Enter : cd positions . - Enter : startIM . - Wait approx 2 minutes until all Drivers and ImHan processesare present. - Verify, by entering : ps -ef 1 grep Drv , that all 20 drivers are present : .:.. DrvUtl 32 23 200 service .. . . . . . .. . . .. . . . . . .. *.. DrvRdr 14 16 500 service . . . . . . . . . . . . . . .* ... DrvOut 13 18 500 service . . . . . . . .. . . .. . . . . . .:.. DrvStr 22 14 500 service . . . . . . . . . . . . . . . . .:.. DrvStr 21 13 500 service . . . . . .. . . . . . . . .. *.. DrvStr 20 12 500 service . . . . . . . .. . . .. . . . . . . ... DrvDsp 19 11 500 service . . . . . . . . . . . . . . . . .. *.. DrvDsp 18 10 500 service . . . . . .. . . . . . . . service . . . . . . . .. . . .. . . . .:.. DrvWsh 16 15 500 .. *.. Dt-vTpt 11 22 200 service . . . . . .. .. . . .. .. . .... DrvInc 31 9 500 service . . . . . . . .. . . .. . . . .... DrvInc 30 8 500 service . . . . . . . .. . . .. . . . . . service . . . . . . . . . . . . . . .... DrvInc 29 7 500 .. -.. DrvInc 28 6 500 service . .. . . .. .. . . .. . . . . . .. *.. DrvInc 27 5 500 service . . . . . . . . . . . . . . .:.. DrvInc 26 4 500 service . . . . . .. .. . . .. . . . .. *.. DrvInc 25 3 500 service . . . . . . . .. . . .. . . . . . .... DrvInc 24 2 500 service . . . . . . . . . . . . . . .. *.. DrvInc 23 1 500 service . . . . . . . .. . . .. . . . . . . * . .. DrvIn 12 17 500 service . . . . . . . . . . . . . .
TROUBLESHOOTING
95
- Verify, by entering : ps -ef 1 grep Han , that all 6 ImHan processes are present service service service service service service ..... ..... ..... ..... ..... ..... ..:..:... ..:..:... ..:..:... ..:..:... ..:..:... ..:..:... .:.. .:.. .:.. .:.. .:.. .:.. /usr/mpp/IM/exe/ImHanCfg ImHanTpt ImHanPlt ImHanMod ImHanStr ImHanNn
- Do not proceed until all 26 processes are present ! Note : The startup is finished as soon as the red LED is extinguished .
6.1.2. Description of the procedure :
- Enter : cyclemod . This will start the dry module duration test program. Six plate carriers must be entered. Follow the instructions exactly as displayed on the screen. It is recommended to abort the program, by pressing the <de1 > key, when all plates are presented either by the input or output module. This makes it easier to remove the plates. Dont forget to remove all remaining plates before starting any other program ! During the test execution a logging file OM TST.log is created. This file can be checked (using vi OM TSTJog in directory /usr/service/positions) for useful information in case errors occurred .
6.2. Module functions duration test
The cycletst program will run continuously until an error condition appears, until one of the front wash liquid containers becomes empty, or until the <de1 > key is pressed. Real washing and dispense activities are performed, as well short incubations. Shaking in reader, dispense and washer module also is done. The plate carriers are moved from module to module, using them all at least once. This program is almost identical to Autocalibration, which is accessible by the operator under Utilities in the main program (refer to the Operating Manual for details) .
The preparation is identical to that explained in paragraph 6.1.1.

- enter : cycletst This will start the wet duration test program. Follow all the instructions displayed on the screen.
TROUBLESHOOTING
96
It is recommended to abort the program, by pressing the <de1 > key, when all plates are presented either by the input or output module. This makes it easier to remove the plates . Dont forget to remove all remaining plates before starting any other program! During the test execution a logging file OM TST.log is created. This file can be checked (using vi OM TST.log) for useful information in case errors occurred .
6.3. Ouality control test
The modtest program is a QC program to check all essential and functional properties of the MPP 3000.
The preparation is identical to that explained in paragraph 6.1.1.

- Enter : modtest . A selection menu is displayed :

1 2 3 4 0 Incubator + Storage Washer Reader Dispense End this program
Select the module to test. This will start the QC test program. Now follow the instructions as displayed on the screen . If during the execution of this program an error occurs, then interrupt the test by pressing the < de1> key . Dont forget to remove all remaining plates before starting any other program . During the test execution, a logging file OM TST.log is created . This file contains the OD values from the plates which have-been read. The file can also contain useful information for troubleshooting in case errors occurred. With the command vi OM TST.log you can view the file contents .
6.4. IM shutdown m-ocedure
When finished using one or more of the test program(s), the following procedure should be performed to kill all started processesin a decent way : - Stop and quit a running test program by pressing the < de1> key - Enter : stopIM . When finished working with the MPP 3000, then perform the Unix shutdown procedure before switching off the system, refer to par. 5.5.
TROUBLESHOOTING
97
6.5. The Bitbus Monitor
The Bitbus Monitor command set can be used as a diagnostic service tool for the MPP 3000 .
6.51. Startup procedure : (follow either procedure A or B )
When you are already in the directory /usr/service/positions then : - Verify by entering : ps -ef that no IM processes are running ! If so then perform the IM shutdown procedure explained in par. 6.4. - Enter : BBM . The BBM command prompt appears : UNIX-BBM > and commands can now be entered. - Be sure that the MPP 3000 application software is not running ! If still running then quit the main program using End Operations and Shutdown . - Boot the system. At the login prompt simultaneously press the ALT and F2 key to activate another console . - Login as : service . (example Ssn92026) . - Enter password : Ssnyyxxx where yy is the year of assembly and xxx the serial number of the MPP 3000 you are working on, this number is also displayed above the login prompt. - Enter : cd positions . - Enter : BBM . The BBM command prompt appears : UNIX-BBM > and commands can now be entered.
6.5.2. General information
Enter a command by typing it along with any parameters required. Then press the <enter > key. The UNIX-BBM is not case sensitive, uppercase or lowercase may be entered. After the command executes, the status is displayed as an exception code and data bytes are returned. Typically the following will be seen on the next line after either the command or the information displayed by the command : UNIX-BBM > Msg. length : Node : Command : DATA : 0000 : E$OK UNIX-BBM > (command)
1 IZue) (command byte) (data bytes received from the node) (exception code) (new command line)
Pressing the DEL, key, entering the command quit or exit leaves the Bitbus Monitor and returns to the Unix operating system .
.-.
TROUBLESHOOTING
98
0000 : E$OK is an exception code indicating that the command executed correctly (without error) and the UNIX-BBM is ready for another command. If a command requires parameters and those are not entered, or have the wrong format, than the command is not executed and the exception code E$ARG$CMD$INVALID is displayed. 0010 : E$SPT (NAK) indicates that the node is in an invalid state for executing the command (communication error with the module or no power connected). 0091 : E$PROTOCOL$ERROR is displayed when there is no response from the node (node not active or no power connected to the node) List of some commands : SYS 1 - 8 : displays information of the active nodes in the range 1 to 8
RESET X : where X is the node id. This initiates a software reset of a node
processor. TMSGnode id length command parameter list This command performs a complete bitbus message transaction to a node. node id : is the byte value of the node to which the message is sent length : is the byte value for the length of the message to send. The length is equal to 7 plus the number of bytes in the parameter list. command : is the byte value of the command to be sent parameter list : data to be sent in the message. The list contains up to length -7 byte values, each separated by a space. Values for parameters must be separated by spaces and are normally entered in hexadecimal notation. If decimal notation is required then the value must be followed by t. (t or T is the only suffix that is allowed) ! : to repeat the previous entered command
DELAY
seconds : waits for the specified period of time
DO filename : executes the commands within a file
A command may be preceded by a number indicating a repetition count Example : 5 do filename : the do command will be executed 5 times. The bitbus monitor treats values as hexadecimal values, unless these values are followed by a t (then they are treated as decimal values). This is shown in the examples underneith: Warning: Bitbus commands do not check whether the commanded operation can be executed without danger or damage. Be very careful and think twice before you enter a command.
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6.53. Bitbus commands for the Transport
system
The transport node ID is 4 A) Label decoder

or: To reset the label decoder. This reset must be given before a new plate carrier tmsg 4 7 246t tmsg 4 8 250t 40
label reading can be executed

tmsg 4 13t 231t To read the label of the plate carrier in the grab. The six returned data bytes are the Hex values (30 to 39) for the ASCII characters 0 to 9. Example : the values 30 30 3137 38 35 are for carrier label no. 001785
B) Transnorter and grab

or: tmsg 4 7 210t tmsg 4 8 250t 80
To initialize the transport system. First the grab and then the arm goes to the home position.
tmsg 4 8 250t 8
To initialize only the arm (Y direction) from the transport system Note : The grab may hit the storage pins if not high enough !!
tmsg 4 8 250t 10
To initialize only the grab (Z direction) from the transport system

tmsg 4 8 250t 1
To initialize all functional groups of the transport system : the grab, the arm, the input and the output module
tmsg 4 llt 234t 1
This command returns four data bytes for the status of the transport system Explanation of the returned data bytes : Byte 1 : Hex number of the last occurred error. Refer to table on next page Byte 2 : the number of the process on which the error occurred 0 = pickup, 1 = putdown, 2 = move with plate, 3 = move without Byte 3 : the number of the phase the process was in Byte 4 : status flags. Convert the Hex value to binary word 1= 0 = false, bit 0 = processor or module software not OK 1= 0 = false, bit 1 = label reader not OK 0 = false, 1= bit 2 = Y drive not OK 0 = false, 1= bit 3 = Z drive not OK bit 4,5, 6 and 7 are dummy bits
plate true true true true
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Table of error codes : a) precondition violations Hex no OA 64 96 97 98 99 A0 Al A2 A3 AB AC B4 B5 B6 Dee no 10 100 150 151 152 153 160 161 162 163 170 171 172 180 181 182 Error name value out of range transport busy input initialization busy input busy input open, unable to move up input up, unable to open output initialization busy output busy output open, unable to move up output up, unable to open input not out input not down or in input not up output not out. output not down or in output not up
b) process errors 01 61 63 65 7A 7D 82 85 8D 8E 8F 90 91 92 93 94 B7 C8 c9 CA CB cc 1 97 99 101 122 125 130 133 141 142 143 144 145 146 147 148 173 183 200 201 202 203 204 divide by zero error power failure transport in error condition limit or max sensor defect no carrier in grab nothing to put plate on protocol error during reading Y correction too big at pickup or putdown limit Y left active end Y left active limit Y right active end Y right active limit Z lower active end Z lower active limit Z upper active end Z upper active input in error output in error left thumb too high right thumb too high both thumbs too high left thumb too low right thumb too low
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Hex no CD D2 D3 D4 D5 D6 D7 D8 D9 DA DB DC DD DE E6 E7 ES E9 EE EF FO Fl F2 F3 F4 F5 FF
Dee no 205 210 211 212 213 214 215 216 217 218 219 220 221 222 230 231 232 233 23% 239 240 241 242 243 244 245 255
tmsg 4 7- 2381
Error name both thumbs too low left finger not open right finger not open both fingers not open left finger not closed right finger not closed both fingers not closed left finger opened right finger opened both fingers opened left finger closed right finger closed both fingers closed fingers opened too long X displacement into back max X displacement into front max X displacement into left ma.x X displacement into right max out of temperature range out of grab sensor drift range left thumb sensor range error right thumb sensor range error left finger sensor range error right finger sensor range error Y displacement sensor range error X displacement sensor range error ADC fault
To clear an error flag in the transport system C) Plate InDut and Output
or: tmsg 4 7 200t tmsg 4 8 250t 2
To initialize the plate input module. The carriage is, after initialization, down and inside the module in home position.
tmsg 4 7 202t
To move the plate input carriage to the open position.

tmsg 4 7 201t
To move the plate input carriage to the closed position
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tmsg 4 8 203t 1
To move the plate input stack to the upper entering plate position where the grab can pick up a plate from the stack. Note : This command can only be executed when the plate stack is in home position
tmsg 4 8 203t 2
To move the plate input stack to the upper receiving plate position where the grab can put down a plate on the stack Note : This command can only be executed when the plate stack is in home position
tmsg 4 7 204t
To move the plate input stack to the bottom position

or: tmsg 4 7 205t tmsg 4 8 250t 4
To initialize the plate output module. The carriage is, after initialization, down and inside the module in home position.
tmsg 4 7 207t
To move the plate output carriage to the open position.

tmsg 4 7 206t
To move the plate output carriage to the closed position

tmsg 4 8 208t 1
To move the plate output stack to the upper entering plate position where the grab can pick up a plate from the stack. Note : This command can only be executed when the plate stack is in home position
tmsg 4 8 208t 2
To move the plate output stack to the upper receiving plate position where the grab can put down a plate on the stack Note : This command can only be executed when the plate stack is in home position
tmsg 4 7 209t
To move the plate output stack to the bottom position

tmsg 4 1st 233t
This command returns eight data bytes for the status of both output modules. Explanation of the returned data bytes : Byte 1 : current processing status of the plate input 0 = procedure failure, 1 = standby, 2 = initializing, 3 = Byte 2 : current processing status of the plate output 0 = procedure failure, 1 = standby, 2 = initializing, 3 = Byte 3 : number of plates detected on the input stack during bottom to top position, range 0 to 6
plate input and moving moving last move from
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Byte 4 : number of plates detected on the output stack during last move from bottom to top position, range 0 to 6 Byte 5 : flags from input module sensors. Convert the Hex value to a binary word bit 0 = front position sensor 1 = not activated 0 = activated bit 1 = rear position sensor 0 = activated 1 = not activated bit 2 = top position sensor 1 = activated 0 = not activated bit 3 = bottom position sensor 1 = not activated 0 = activated bit 4 = module not OK 0 = not activated 1 = activated bit 5 to 7 are dummy bits Byte 6 : flags from output module sensors. Convert the Hex value to a binary word. Refer to the list under byte 5 Byte 7 and 8 : byte 7 is the LSB and byte 8 is the MSB for the current MPP temperature (measured at the storage positions) in O.lC. Convert the Hex values to decimal values. Range is 0 to 610. Valid temperature starts from 100. A 0 means a bad reading
6.5.4. Bitbus commands for Incubator modules
The incubator node ID is 8

tmsg 8 8 200t By1
To initialize the selected incubator module --> write in parameter byte (Byl) as the number of the incubator module : range = 0 to 8 NOTE : the incubator numbering is different between Unix and BBM ! Incub 1
6
Incub
2 5
Incub
3 2
Unix
no ----> ----->
BBM no Unix
no ---> ----->
Incub
5 7
Incub
6 4
Incub
7 3
BBM no Unix
no ---> --->
Incub 9
8
BBM no
tmsg 8 8 219t
To clear the error flag of the selected incubator --> write in parameter byte (Byl) as the number of the incubator module : range = 0 to 8
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tmsg 8 lot 218t By1 By2 By3
To move the carriage to the load or open position --> write in first parameter byte (Byl) as the number of the incubator module : range = 0 to 8 --> write in second parameter byte (By2) as the Hex value of the LSB for the carriage steps to the load position --> write in third parameter byte (By3) as the Hex value of the MSB for the carriage steps to the load position NOTE : Refer to the .incl to .inc9 files inside ACT.all for the exact MSLOADPOS value in micrometers. The carriage step size is 225 micrometers Example : MSLOADPOS = 216000 216000 / 225 = 960 steps or 03CO Hex Byte2 or LSB =CO, Byte3 or MSB = 03
tmsg 8 8 201t By1
To move the carriage to the park or close position --> write in parameter byte (Byl) as the number of the incubator module : range = 0 to 8
tmsg 8 8 202t By1
To move the carriage to the cooling position --> write in parameter byte (Byl) as the number of the incubator module : range = 0 to 8
This command provides direct heating of plates from the selected module --> write in first parameter byte (Byl) as the number of the incubator module : range = 0 to 8 --> write in second parameter byte (By2) : Use 1 for upper plate heater on, or 0 for upper plate heater off --> write in third parameter byte (By3) : Use 1 for lower plate heater on, or 0 for lower plate heater off NOTE : There is no heater control active and the heating goes on until switched off by sending a new command with 0 (zero) in parameter bytes 2 and 3 for that incubator !
tmsg 8 9 213t By1 By2
This command provides direct control of the cooling fans for the selected module --> write in first parameter byte (Byl) as the number of the incubator module : range = 0 to 8 --> write in second parameter byte (By2) : Use 1 for cooling fans on, or 0 for cooling fans off
. .I. _... . .--. _._l--ll-11~
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tmsg 8 18t 214t By1
This command returns eleven data bytes for the current status of all sensors from the selected incubator --> write in parameter byte (Byl) as the number of the incubator module : range = 0 to 8 Explanation of the returned data bytes : Byte 1 : the number of the selected incubator module Byte 2 : the current position of the plate carriage 1 = close position, 2 = cool position, 3 = load position, 4 = position, 5 = moving Byte 3 and 4 : byte 3 is the LSB and byte 4 is the MSB for upper plate temperature in O.lC. Range is 0 to 1040. Convert the Hex values to a decimal value Byte 5 and 6 : byte 5 is the LSB and byte 6 is the MSB for lower plate temperature in O.lC. Range is 0 to 1040. Convert the Hex values to a decimal value Byte 7 : module sensor flags. Convert byte to a binary word bit 0 = home sensor status 0 = not activated 1 = activated bit 1 = max out sensor status 0 = not activated 1 = activated bit 2 to 7 are dummy bits Byte 8 and 9 : byte 8 is the LSB and byte 9 is the MSB for the absolute carriage position. Range is -60 to 1010. Convert the Hex values to a decimal value Byte 10 and 11 : byte 10 is the LSB and byte 11 is the MSB for the distance between home and max out sensor. Range is 0 to 1070
6.5.5. Bitbus commands for Washer module
The washer node ID is 2

tmsg 2 8 249t 1
To initialize all functional groups in the washer

or tmsg 2 7 200t tmsg 2 8 249t 2
To initialize the module carriage

tmsg 2 9 202t By1 By2
To move the carriage to the load or open position: --> write in first parameter byte (Byl) as the Hex value of the LSB for the carriage steps to the load position. -- > write in second parameter byte (By2) as the Hex value of the MSB for the carriage steps to the load position. NOTE : Refer to the .wshl file inside ACT.all for the exact MSLOADPOS value in micrometers. The carriage step size is 112,5 micrometers. Example : MSLOADPOS = 145000; 145000 / 112.5 = 1289 steps or 0509 Hex. Byte1 or LSB =09, Byte2 or MSB = 05.
tmsg 2 8 203t 0
To move the module carriage to the park or close position.

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or
tmsg 2 7 225t tmsg 2 8 249t 4
To initialize the dispense Pump

tmsg 2 8 249t 10 To initialize the manifold assembly tmsg 2 8 232t 1 To move the manifold clockwise up tmsg 2 8 232t 2 To move the manifold counter-clockwise up tmsg 2 8 232t 4 To move the manifold clockwise down tmsg 2 8 232t 8
To move the manifold counter-clockwise down

tmsg 2 8 214t 1
To switch the vacuum pump on

tmsg 2 8 214t 0
To switch the vacuum pump off

tmsg 2 8 250t
This command returns one data byte for the status of all the washer module sensors. Convert the Hex value to a binary word bit 0 = carriage home sensor 0 = not activated 1 = activated bit 1 = carriage max out sensor 0 = not activated 1 = activated bit 2 = geometry sensor ignore value bit 3 = dispense pump home 0 = not activated 1 = activated bit 4 = vacuum detection 0 = no vacuum 1 = vacuum bit 5 = manifold present 0 = not present 1 = present bit 6 = manifold up 0 = not activated 1 = activated bit 7 = manifold down 0 = not activated 1 = activated
tmsg 2 8 230t By1
To select the wash liquid container where liquid should be taken from --> write in parameter byte (Byl) as the number of the wash liquid container to select. Range is 1 to 4
tmsg 2 7 224t
To clear an error flag in the washing system.
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tmsg 2 lot 223t
This command returns three data bytes for the status of the container sensors Explanation of the returned data bytes : Byte 1 : convert the Hex value to a binary word 1 = inserted 0 = not inserted bit 0 = container 1 coupling 1 = inserted 0 = not inserted bit 1 = container 2 coupling 1 = inserted 0 = not inserted bit 2 = container 3 coupling bit 3 to 7 are dummy bits Byte 2 : convert the Hex value to a binary word bit 0 = container 1 coupling changed 0 = not changed 1 = changed bit 1 = container 2 coupling changed 0 = not changed 1 = changed bit 2 = container 3 coupling changed 0 = not changed 1 = changed bit 3 to 7 are dummy bits Byte 3 : convert the Hex value to a binary word 1 = empty bit 0 = container 1 volume 0 = not empty 1 = empty bit 1 = container 2 volume 0 = not empty 1 = empty bit 2 = container 3 volume 0 = not empty bit 3 to 7 are dummy bits
tmsg 2 22t 222t
This command returns fifteen data bytes for the status of all functional elements in the washer module Explanation of the returned data bytes : Byte 1 : the current activity of the washer 0 = busy, 1 = standby, 2 = pausing, 3 = initializing, 4 = testing carriage, 5 = washing, 6 = priming, 7 = shaking Byte 2 : convert the Hex value to a binary word 1 = occurred bit 0 = process failure O=OK 1 = in error 0 = OK bit 1 = carriage drive 1 = in error bit 2 = dispense pump drive O=OK 1 = in error bit 3 = interface memory 0 = OK bit 4 to 7 are dummy bits Byte 3 : convert the Hex value to a binary word 1 = out of program 0 = OK bit 0 = internal controller 0 = not been reset 1 = been reset bit 1 = reset internal controller 1 = inconsistent 0 = OK bit 2 = internal controller memory bit 3 to 7 are dummy bits Byte 4 : convert the Hex value to a binary word 0 = not at load 1 = at load bit 0 = carriage load position 0 = not at park 1 = at park bit 1 = carriage park position 1 = not OK 0 = OK bit 2 = geometry 1 = plate present 0 = no plate bit 3 = microplate present bit 4 to 7 are dummy bits Byte 5 and 6 : byte 4 is the LSB and byte 5 is the MSB for the actual carriage position. Range is -10000 to 10000. Convert the Hex values to a decimal value
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Byte 7 and 8 : byte 6 is the LSB and byte 7 is the MSB for the distance between max in and max out sensor. Range is 0 to 20000. Convert the Hex values to a decimal value Byte 9 : the number of the last occurred error. Refer to table : Hex no 00 09 OA OB oc OE OF 10 11 14 15 16 17 1E 1F 20 21 28 29 2A 2B 2c 2D 2E 33 37 38 39 3A 3c 3D 3E 3F 40 41 42 43 44 45 46 Dee no 0 9 10 11 12 14 15 16 17 20 21 22 23 30 31 32 33 40 41 42 43 44 45 46 51 55 56 57 58 60 61 62 63 64 65 66 67 68 69 70 Error name no error busy initializing carriage not initialized carriage init busy carriage busy moving plate geometry error carriage drive error max in sensor activated max out sensor activated dispense pump not initialized dispense pump init busy dispense pump busy moving dispense pump drive error pausing busy no vacuum detected vacuum pump is on vacuum pump not off manifold not initialized manifold init busy manifold busy moving manifold drive error manifold not inserted no plate carrier detected manifold not in upper position no plate detected dispense washing busy plate washing busy strip washing busy priming or washing busy no washing mode set priming busy shaking busy container 1 not inserted container 1 empty container 2 not inserted container 2 empty container 3 not inserted container 3 empty no container selected processing failure
__---_l _._ .____. -.._ _.l_--_ll-l-
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Hex no 50 51 52 65 66 67 68 69 6A 6B
Dee no 80 81 82 101 102 103 104 105 106 107
Error name container 1 status changed container 2 status changed container 3 status changed timer busy buffer overflow memory error module communication error module reset error slave invalid command slave invalid parameter
Byte 10 : manifold present flag, 0 = manifold inserted, 1 = manifold not inserted Byte 11 : vacuum flag, 0 = vacuum off, 1 vacuum on Byte 12 : valve flags. Convert the Hex value to a binary word 1 = activated 0 = not activated bit 0 = valve 0 1 = activated bit 1 = valve 1 0 = not activated 1 = activated 0 = not activated bit 2 = valve 2 1 = activated 0 = not activated bit 3 = valve 3 bit 4 to 7 are dummy bits Byte 13 : manifold drive flags. Convert the Hex value to a binary word 1 = in position 0 = not in position bit 0 = manifold upper position 1 = in position bit 1 = manifold down position 0 = not in position 1 = moving up 0 = not moving up bit 2 = manifold moving up 1 = moving down 0 = not moving down bit 3 = manifold moving down bit 4 to 7 are dummy bits Byte 14 : drive flags. Convert the Hex value to a binary word 1 = initializing 0 = not initializing bit 0 = dispense pump drive 1 = initializing 0 = not initializing bit 1 = carriage drive 1 = initializing 0 = not initializing bit 2 = manifold drive bit 3 to 7 are dummy bits Byte 15 : remaining wash cycles. Convert the Hex values to a decimal value Range is 0 to 20
6.5.6. Bitbus commands for Dispense module
The upper dispense node ID is 1 and the lower dispense node ID is 3

tmsg 1 8 249t 1 tmsg 3 8 249t 1
To initialize all functional groups in the selected dispense module

tmsg 1 7 242t tmsg 3 7 242t
To move the drives to the park position so that the reagent door can be opened
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tmsg 1 7 200t or: or: tmsg 3 1 8 7 249t 200t 2 tmsg 3 8 249t 2
(upper)
gzz;
(lower) To initialize the carriage of the selected dispense module

tmsg 1 7 205t or: or: tmsg 3 1 8 7 249t 205t 4 tmsg 3 8 249t 4
(upper)
$z;
(lower) To initialize the needle head drive of the selected dispense module 8 249t 10 (upper) 7 207t (lower) or: 8 249t 10 (lower) To initialize the pump select drive of the selected dispense module
or: or: or: tmsg tmsg tmsg tmsg 1 1 3 3 7 8 7 8 210t 249t 8 210t 249t 8 Eeri u er tmsg tmsg tmsg tmsg 1 1 3 3 7 207t (UPPer)
(lower) (lower) To initialize the pump drive of the selected dispense module
tmsg 1 9 202t By1 By2 (upper) tmsg 3 9 202t By1 By2 (lower)
To move the carriage to the load or open position --> write in first parameter byte (Byl) as the Hex value of the LSB for the carriage steps to the load position --> write in second parameter byte (By2) as the Hex value of the MSB for the carriage steps to the load position NOTE : refer to the .dspl or .dsp2 file inside ACT.all for the exact MSLOADPOS value in micrometers. The carriage step size = 112,5 micrometer Example : MSLOADPOS = 65250 65250 / 112.5 = 580 steps or 0244 Hex Byte1 or LSB =44, Byte2 or MSB = 02 (lower) To move the carriage to the park or close position.
tmsg 1 8 209t By1 (upper) tmsg 3 8 209t By1 (lower) tmsg 1 8 203t 0 tmsg 3 8 203t 0 (UPPer)
To move the pump select drive to a specified pump position. --> write in parameter byte (Byl) as the number of the pump. Range is 1 to 6
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(upper) (lower) This command returns six data bytes for the status of all the sensors from the dispense module and reagent door. Explanation of the returned data bytes : Byte 1 : convert the Hex value to a binary word 0 = not activated 1 = activated bit 0 = carriage home sensor 0 = not activated 1 = activated bit 1 = carriage max out sensor 0 = not activated 1 = activated bit 2 = carriage max in sensor bit 3 = carriage geometry sensor ignore value bit 4 to 7 are dummy bits Byte 2 : convert the Hex value to a binary word bit 0 = needle head home sensor 1 = not activated 0 = activated bit 1 = needle head park sensor 0 = not activated 1 = activated bit 2 to 7 are dummy bits Byte 3 : convert the Hex value to a binary word bit 0 = reagent door sensor 0 = not activated 1 = activated bit 1 = pump select home sensor 0 = not activated 1 = activated bit 2 = pump home sensor 0 = not activated 1 = activated bit 3 to 7 are dummy bits Byte 4 : convert the Hex value to a binary word bit 0 = syringe 1 present sensor 0 = not activated 1 = activated 0 = not activated 1 = activated bit 1 = syringe 2 present sensor bit 2 = syringe 3 present sensor 0 = not activated 1 = activated bit 3 = syringe 4 present sensor 0 = not activated 1 = activated 0 = not activated 1 = activated bit 4 = syringe 5 present sensor bit 5 = syringe 6 present sensor 0 = not activated 1 = activated bit 6 and 7 are dummy bits Byte 5 : convert the Hex value to a binary word bit 0 = syringe 1 down sensor 0 = not activated 1 = activated = syringe 2 down sensor 0 = not activated 1 = activated bit 1 bit 2 = syringe 3 down sensor 0 = not activated 1 = activated bit 3 = syringe 4 down sensor 0 = not activated 1 = activated bit 4 = syringe 5 down sensor 0 = not activated 1 = activated bit 5 = syringe 6 down sensor 0 = not activated 1 = activated bit 6 and 7 are dummy bits Byte 6 : output of the ADC of the last used needle for prime or dispense
tmsg 1 13t 238t tmsg 3 13t 238t tmsg 1 7 228t (upper) tmsg 3 7 228t (lower)
To clear an error flag in the dispense system. tmsg 1 lot 227t (upper) tmsg 3 lot 227t (lower) This command returns three data bytes for the status of all the sensors from the dispense module and reagent door. Explanation of the returned data bytes :
112 / :\ : ::
Byte 1 : the current activity of the dispense 0 = busy, 1 = standby, 2 = pausing, 3 = dispensing, 4 = shaking, 5 = initializing, parking, calibrating, 6 = testing carriage, 7 = priming Byte 2 : the number of the last occurred error Hex no Dee no Error name
0 no error 00 12 dual port RAM communication error oc communication error bitbus/interface 13 OD 14 communication error interface/module OE carriage drive error 111 6F 112 head drive error 70 113 selection drive error 71 114 pump drive error 72 130 carriage drive not initialized 82 131 head drive not initialized 83 132 selection drive not initialized 84 133 pump drive not initialized 85 134 dispense not initialized 86 140 busy processing 8C 141 command ignored 8D 142 selected pump not present BE pump drive not in home position 143 8F 144 one of pumps is not down 90 145 reagent door is open 91 146 plate geometry is not OK 92 147 bubble detected during dispense 93 148 no plate present to dispense 94 149 no pump selected 95 -150 dispense module in error 96 151 no pump needle combination set 97 FF 255 illegal state of process Byte 3 : convert the Hex value to a binary word bit 0 = internal controller 0 = OK 1 = out of program 0 = not been reset 1 = been reset bit 1 = reset internal controller bit 2 to 7 are dummy bits
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6.5.7. Bitbus commands for Reader module
The reader node ID is 5

tmsg 5 8 249t 1
To initialize all functional groups in the reader module

tmsg 5 7 2OOt tmsg 5 8 249t 2 or: To initialize the carriage tmsg 5 8 249t 4 To initialize the filter drive tmsg 5 7 202t To move the carriage to the load or open position tmsg 5 7 203t To move the carriage to the park or close position. During the move a geometry
check is always performed.

This command stores the wavelength of the filter at the specified position --> write in first parameter byte (Byl) as the position number of the filter to install. Range is 1 to 8 --> write in second (By2) and third parameter byte (By3) as the Hex value for the LSB and MSB of the filter wavelength to install. Range is 400 to 700 Example : tmsg 5 lot 246t 6 B2 02, installs a 690nm filter in position 6
tmsg 5 8 247t By1
This command deletes a filter from the filter list --> write in first parameter byte (Byl) as the position number of the filter to remove. Range is 1 to 8
tmsg 5 23t 254t
This command returns sixteen data bytes for the installed filters from positions 1 to 8. Convert the Hex values to decimal values Explanation of the returned data bytes : Byte 1 and 2 : LSB and MSB for the filter wavelength at position 1 Byte 3 and 4 : LSB and MSB for the filter wavelength at position 2 Byte 5 and 6 : LSB and MSB for the filter wavelength at position 3 Byte 7 and 8 : LSB and MSB for the filter wavelength at position 4 Byte 9 and 10 : LSB and MSB for the filter wavelength at position 5 Byte 11 and 12 : LSB and MSB for the filter wavelength at position 6 Byte 13 and 14 : LSB and MSB for the filter wavelength at position 7 Byte 15 and 16 : LSB and MSB for the filter wavelength at position 8
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tmsg 5 8 253
By1
This command moves the filter drive to the specified position --> write in parameter byte (Byl) with the position number for the filter drive Range is 0 to 9. Use 0 = home and 9 = eject
tmsg 5 8 251t 1
This command switches on all the lamps NOTE : DONT LEAVE THE LAMPS SECONDS !
tmsg 5 8 251t 0
ON FOR LONGER
THAN
30
This command switches off all the lamps

tmsg 5 26t 250t
This command returns nineteen data bytes for the status of all the sensors of the reader module Explanation of the returned data bytes : Byte 1 : convert the Hex value to a binary word bit 0 = carriage home sensor 0 = not activated 1 = activated 0 = not activated 1 = activated bit 1 = carriage max out sensor bit 2 = carriage geometry sensor 0 = not activated 1 = activated 0 = not activated 1 = activated bit 3 = filter home sensor bit 4 to 7 are dummy bits Byte 2 and 3 : LSB and MSB for the current light detection values from the reference channel 9. Convert the Hex values to a decimal value. Range is 0 to 4095. Byte 4 and 5 : LSB and MSB for the current light detection values from channel 8 Byte 18 and 19 : LSB and MSB for the current light detection values from channel 1. Convert bytes to the decimal values. Range is 0 to 4095.
tmsg 5 7 211t To clear all error flags in the reader.
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7. General
information
Preventive maintenance on the MPP 3000 should be done at least twice a year and should only be performed by persons authorized by Organon Teknika. WARNING : The MPP 3000 must be considered as potentially contaminated with
biohazardous material. Elaborate precautions should always be taken to avoid possible infection. Always use disposable gloves and protective clothing. All ESD (Electra Static Discharge) and electrical safety precautions must be observed to protect the equipment from damage.
Preventive maintenance consists of two main steps : A) overall cleaninp of the instrument The cleaness is very important for a good functioning of the system. A cleaning (and/or disinfection) procedure should be executed on a regular basis by the operator. This is to prevent loss of performance due to dirt and/or biological growth inside the MPP 3000 system. If the user did not recently perform a cleaning then it should be done before any other activity. A cleaning must always be executed after a disinfection of the system. The procedures are explained more in detail in the chapter Cleaning and Disinfection. B) nreventive maintenance and functional verification After a cleaning the MPP 3000 system should be verified on its overall functionality. You can use the protocols available under QC Check of the application program or one of the service programs (e.g. cycletest). Always record all maintenance check maintenance on the panel from the MPP performed activities and observations on the preventive list. Note also the date of each performed preventive service logging cards available in the history box of the back 3000.
7.1. Required tools, materials and Darts
- vacuum cleaner - lint free cloth - sponge - mild detergent - distiled water - alcohol 70% or ethanol 70% - gluteraldehyde 50% - silicon tubing 8*12 03921 07412 - filter sheet for washer 07233 - dustfilter for reader - 3 AAA type penlite batteries 1.5 Volt, (Alkaline) - calibrated voltmeter - set of standard hand tools - cleaning tool for incubator 08515 08467 - Accu lube oil
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7.2. Procedure - General -
Perform an overall cleaning (eventually preceeded by a disinfection). Refer to chapter 8 Cleaning and Disinfection for full details. Remove all visible dust with a vacuum cleaner. Clean the module carriages and remove all liquid spillages. Remove all panels and inspect the wiring and all connectors for proper connections. Check functionality of front sliding door switches.
- Power supplies -
Check functionality of the UPS : Pull the mains cord loose and switch on the MPP 3000 and check that the computer boots. Verify that approximately every 30 seconds a short beep is generated by the UPS (this indicates that the built in batteries are fully charged). Check that the fan of the UPS is running and dust free. Check the +5 Volt and + /-15 Volt at the busbar connections (refer to paragraph 3.2.1.4.). The acceptable range for the +SVolt is between 5.20 and 5.25 Volts. Check the +24 Volt value at the busbar connections. The acceptable range is between 25.20 and 25.25 Volts.
- Incubator modules -
Verify cleaness of both ceramic heating plates and clean them if necessary. The carriage system of the Incubator modules needs regular lubrication to prevent noise and vibrations while moving. Push the carriage inside the module and put one drop of Accu lube oil on top of each sliding bar. Manually move the carriage a few times back and forth to spread the oil. Check functionality of each incubator using the QC Check protocols or the modtest QC program.
- Washer module -
Check performance of manifold : remove manifold and rinse it thoroughly with distilled water. Check that dispense or aspirate tips are not clogged (use declogging tool to remove any obstruction). Reposition and secure the manifold with the knurled knob. Remove the metal screen from the washer filter assembly and replace the filter paper sheet. Rinse the carriage prime cup and the drain system with gluteraldehyde. If algae growth is observed in the drain tubings then replace them. Check the status of the liquid container filling plugs. Check that the filters in the suction tubes are not clogged. Verify the functionality of the container couplings. Verify the overall washer functionality using the QC Check protocols or the modtest QC program. Verify that air bubbles do not appear in the connection tubes to the washer inlet ports.
MAINTENANCE
117
- Dispense modules -
Wipe off all reagent spillages in the reagent doors and around the needle head. Check the locking function of reagent doors. Check all the pump piston drivers for low friction and apply a drip of oil. Clean or replace the dust filters of the reagent door cooling fans and verify that the fans are running. Rinse the carriage prime cup and the drain system with gluteraldehyde. If algae growth is observed in the drain tubings then replace them. Verify the overall functionality of both dispense modules using the QC Check protocols or the modtest QC program.
- Reader module -
Slide out the filter tray and clean all the filters. Remove the reader module and clean or replace the dust filter on the lamp assembly.Check the voltage of battery set. Replace batteries when the voltage is lower than 4.2 Volts. Warning : replacement of the batteries should only be done while power is applied to reader module. This will prevent loosing the contents of the RAM (filterlist). If the carriage of the reader is noisy or vibrating while moving then lubricate the system by putting one drop of Accu lube oil on the left sliding bar and manually move the carriage a few times back and forth to spread the oil. Check the functionality of the reader using the field testplate with the QC Check protocols or the modtest QC program. Verify that the measured OD values obtained from the field testplate fall within the given tolerances for all the installed filters.
- Transport and Grab -
The bearings and sliding bars of the transport system are maintenance free. Wipe off, with a dry lint free cloth, any dust which has built up on the sliding bars or at the lower guiding bar.
!! Do not lubricate the screw shafi or the sliding bars !!
Verify free movement of the fingers and thumbs of the grab assembly. Check parallelism of the grab at the plate storage and in the input or output window (refer to the instructions in the chapter Replacement Instructions). Check functionality of the plate carrier label decoder. Check the overall functionality by running Autocalibration.
- Input / output module -
Check the carriage for cleaness. Check the sliding resistance of the carriage and the open/close function of the frontpanel doors.
- Final check -
Create and run a dummy test protocol, or run the modtest QC program, or run the cycletst service program for at least one hour to verify the overall functionality of the MPP 3000 system.
7.3. Checklist
The checklist on next page can be copied prior to perform preventive maintenance. Complete and sign off this preventive maintenance check list and provide a copy to the customer.
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118
Check list Preventive Maintenance MPP 3000

Serial number : Location :
ACTION General Overall cleaning Disinfection Vacuum cleaned Module carriages cleaned Wiring and connectors Sliding door switches Power supnlies Functional test UPS Verification + 5 and + /-15 Volt Verification + 24 Volt Incubator modules Heating plates clean Lubricatton carriage Functionality test Washer module Manifold performance Filter sheet Drain system Container filling plugs Filters in suction tubes Container coupling Functionality test No air in tubes Dispense modules Spillages cleaned Locking dispense doors Pump piston drivers Dust filter fans Reagent cooling fans Dram system Functionality test
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119
OK Reader module Filters cleaned Dustfilter lamp assembly Battery voltage > 4.2 Volt Lubrification carriage Functionality test Field testplate OD values Transport and Grab Sliding bars clean Grab, fingers and thumbs Parallelism Grab Functionality test Functionality label decoder Input / output module Sliding resistance carriage Frontpanel doors Hinge shafts Final check Testresult dummy run Modtest QC program Check-list completed Remarks :
ACTION
Field engineer :
Date :
Customer :
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120
FOR YOUR
OWN
NOTES
.
CLEANING
AND DISINFECTION
121
8.1. Cleanine Drocedure
The cleaning procedure should be executed on a regular basis to prevent loss of performance due to dirt and/or biological growth inside the MPP 3000 system. REMARK : If the instrument has been in contact with any infectious material, it must be disinfected, prior to execution of servicing activities, according to the disinfection procedure. After disinfection a complete cleaning is required. WARNING : The
h4PP 3000 must be considered as potentially contaminated precautions shall with biohazardous material all over. Elaborate be taken to avoid possible infection, always use disposable gloves and protective clothing. All Electra Static Discharge and electrical safety precautions must be observed to protect the equipment from damage
Clean the instrument on a regular basis as explained below :

8.1.1. Rewired materials
- vacuum cleaner - lint free cloth - sponge mild detergent 1 gluteraldehyde 50% - alcohol 70%, or ethanol 70% - distiled water - set of standard hand tools - cleaning tool for incubator - ESD service set
- General -
08515 06991
The housing and table of the MPP 3000 can be cleaned using a cloth soaked in a mild detergent. Liquid should not be allowed to enter the instrument. Clean the monitor screen with a lint free cloth. Remove the front fluid bottles and rinse them with distiled water (shake them vigorously for an effective cleaning). Rinse the filling plugs and clean the suction filters with hot water. Open the dispense reagent doors and discard all disposable syringes and reagent bottles. Wipe off the reagent bottle area with a cloth soaked in alcohol. Open the front sliding doors and remove all debris or foreign objects at the plate storage area. Wipe off all visible liquid spillages in the front area. Pay special attention to the positioning pins of the storage stacks. Check for corrosion and clean thoroughly if necessary. Push the transporter with grab to a safe position (home or just above the output module). Manually open all module carriages and remove any plate carriers if present. Remove backpanel and vacuum all dust, as well as dust collected on the UPS fan.
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AND DISINFECTION
122
- Plate input and output module -
Open front module door, remove plate carriers if present, and pull out the carriage. Clean carriage plate, wipe off all visible liquid spillages and remove any dust. Pay special attention to the positioning pins. Check for corrosion and clean thoroughly if necessary.
- Incubator modules -
Open the module carriage and clean the lower and upper ceramic heating plates using a cleaning tool (or a sponge) sparingly soaked with a detergent solution or alcohol. Then wipe with distilled water and dry.
- Washer module -
Wipe the carriage with a cloth soaked with a detergent solution or alcohol. If necessary remove the carriage from the module. Rinse the carriage thoroughly with distilled water and dry. Check the positioning pins for the plate carrier for corrosion. Clean thoroughly if necessary. Remove the manifold and rinse it thoroughly with distilled water. Check that no dispense or aspirate tips are clogged (use declogging tool to remove any obstruction). Reposition manifold and fasten it with the knurled knob. Inject at least 100 ml of sodium hypochloride solution into the carriage drainage system at the front of the module to clean the drainage channels all the way to the external waste container.
- Dispense modules -
Wipe the carriage with a cloth soaked with a detergent solution or alcohol. If necessary, remove the carriage from the module. Rinse the carriage thoroughly with distilled water and dry. Check the positioning pins for the plate carrier for corrosion. Clean thoroughly if necessary. Inject at least 100 ml of sodium hypochloride solution into the carriage drainage system at the front of the module to clean the drainage channels all the way to the external waste container. Open the reagent doors and wipe off all reagent spillages at the bottle area and around the needle head.
- Reader module -
Wipe the plate carriage with a cloth soaked with a detergent solution or alcohol. Check the positioning pins for the plate carrier for corrosion. Clean thoroughly if necessary. Slide out the filter tray and remove dust from filters using a lint free cloth sparingly soaked in ethanol. Then dry the filters using clean warm (not hot) air
CLEANING
AND DISINFECTION
123
8.2. Disinfection
Drocedure
A disinfection should be executed after spilling contageous material, or before executing servicing activities on the MPP 3000. This procedure is very similar to the cleaning procedure, but instead of using some detergent fluid a disinfection agent is now required. WARNING
: If local or laboratory regulations prescribe regular disinfections then it is advised to clear all formaldehyde vapours since even small traces of formaldehyde affect the biochemistry, in the Elisa tests, resulting in bad test results. After the disinfection, a thorough cleaning is necessary before reuse of the instrument !
The prescribed disinfection procedure is required before the instrument may be transported or prior to shipping it to Organon Teknika for repair. The complete disinfection of the instrument is advised prior to relocating the instrument from one lab to another. Disinfection is not required for the proper functionality of the instrument. WARNING : Always use disposable gloves and protective clothing and operate in a well
ventilated area 8.2.1. Reauired materials
Disinfection aid internal tubing set Disinfection agents : Formaldehyde solution 37% Ammonia Alcohol or ethanol 70% Gluteraldehyde solution 50% Disinfection procedure before transport:
200ml 200ml 500ml 500ml
1 - If still present remove all plate carriers and reagent bottles. Discard the
disposable pumps with needles and tubings. Empty the three front liquid containers and rinse them with disinfectant. As a disinfectant you can use ethanol or any other detergent with the same characteristics. 2 - Open all module carriages and the dispense reagent doors. Remove or slide the plexi doors in a centre position to enable maximum penetration of the formaldehyde vapour. 3 - Formaldehyde vapour can cause damage to the reader filters. These must be taken out and treated separately. Slide out the filter tray. Unlock the metal ring from the left bar and remove the filters from the reader module.
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AND DISINFECTION
124
4 - Remove the waste container(s) and discard all drain tubing under the table. Take care that no potentially infectious fluid can leak out. 5 - The keyboard, mouse, barcode reader, display monitor and the plate carriers should also be disinfected. 6 - Place the disinfection aid (07626) over the MPP 3000 and position the internal tubing set (08242) at following places (see figure on next page) : A - between MPP 3000 unit and the table B - inside the plate input module C - inside the plate output module D - inside the front of the washer module This will assure that the most critical and difficult places are reached with the formaldehyde vapour. 7 - Tape the MPP 3000 disinfection aid airtight to the table. Also tape all slots airtight between the table frame and table top. Do not forget the slot of the drain tubings ! 8 - Prepare the disinfection agents (200 ml of a 37 % formaldehyde solution). Connect the pump unit and the bottles with formaldehyde and ammonia and start the routine box disinfection procedure. required disinfection time : 8 hours required neutralization time : 16 hours 9 - Remove the disinfection aid and tubings after the neutralization phase. 10 - Clean the top cover and the panels of MPP 3000 with alcohol. 11 - Remove manifold and plate carriages from the washer and dispense modules. Put them into a bath of gluteraldehyde solution for 1 hour. Afterwards, rinse them with distilled water. Clean and dry all pieces. 12 - Clean the monitor and keyboard with a mild detergent. 13 - Remove all stains and spots on the MPP 3000 and the table with a disinfectant or alcohol. Pay special attention to the input and output carriage. 14 - Remove the back panel. Remove the waste tubes from the washer and dispense modules. 15 - Clean all tube connections with disinfectant. 16 - Replace the back panel. 17 - Clean the reader filters using a lint free cloth sparingly soaked in ethanol. Then dry the filters using clean warm (not hot) air. Slide out the filter tray of the reader module and replace the filters on the tray . The MPP 3000 is now disinfected and ready to be packed for transportation. Add the completed and signed disinfection forms to the package.
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CLEANING
AND DISINFECTION
/ / f c f
CLEANING
AND DISINFECTION
126
DISINFECTION
STATUS FORM
Shipper: Project number: H Instrument: Serial Number: Number of spare parts:
Date: Return OT International Re ir IRcQA Ot r er:
Disinfertion 11 11 11
Status Never
(mentioned used (neither
by Shipper): for demos) in compliance with the Disinfection Procedure
Used; disinfected
Used; only with water;
not disinfected
Accompanying
Parts (to be specified
in addendum)
Used method 11
of Disinfection With With Other plastic box (see under Manual : : Remarks) bag
[I [I
Reference Number I Remarks
to Service of attached
BROWN-strips
Addenda: Total number Date: Delivep of pages (mcl. addenda): Signed by Dismfection Engrnecr: Sign:
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9. Introduction
The following paragraphs explain and depict the removal and re-installation of panels, modules and parts in the MPP 3000. Any service activity performed on the MPP 3000 must be logged on the system logging cards. They can be found in the history box which is mounted at the inside of the back panel (e.g. serial number of the replaced module, software updates, date of replacement, etc).
WARNING : As any instrument used in medical diagnostics, the MPP 3000 system must be considered as potentially contaminated with biohazardous material all over. Elaborate precautions shall be taken to avoid possible infection. Always use disposable gloves and protective clothing. If the MPP 3000 system can still be operated it is advised, before starting any disassembly, to clean, disinfect, rinse and drain the unit intensively. Refer to chapter Cleaning and disinfection. : Before carrying out any spare part replacement the mains switch should be turned off and the power plug should be disconnected from the mains. Failure to do so can result in a severe electrical shock VenB that the mains switch is indeed in the OFF position. With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the h4PP 3000 to power the computer and video monitor. a complete 6.4 in chapter Calibration for
WARNING
WARNING : The MPP 3000 may only be switched off after pe$orming
Unix shutdown procedure. Refer to paragraph detailed information.
WARNING : Before touching modules or parts all precautions should be taken against
measures for workingin ESD (ElectraStaficDischarge).Takeall necessary

an ESD free environment in order to avoid damage to the instrument orparts. Refer to chapter 4, par. 4.3.1 of the Technical Services Reference Manual.
9.1. Recommended tools

A set of standard hand tools is required : Phillips screwdrivers, pair of pliers, etc. A set of square hooks. A V/A/Ohm multimeter. Adjustment tool for plate I/O module (art. code 08244). Field test plate (art. code 08245). Service extension cables (refer to tools in chapter spare part list).
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9.2. Panels
This chapter describes the procedures for removal and re-installation of the MPP 3000 panels in the following order : 1) The back panel, refer to par. 9.2.1. 2) The top cover, refer to par. 9.2.2. 3) The front panel, refer to par. 9.2.3. 4) Left side panel, refer to par. 9.2.4. 5) Right side panel, refer to par. 9.2.5. 6) The front sliding doors, refer to par. 9.2.6. REMARK : Removing the top cover requires the removal of the back panel first. The front panel is removable without removing any other panel or cover. Removing the side panels requires the removal of the back panel and the front panel.
9.2.1. The back panel

A) Removal STEP 1: Loosen the four screws accessible through the 4 holes of the back anel at the rear but do not remove them (Fig. BACK 2 / BACK 1 step 1 & 2P .
STEP 2 : Slightly lift up the back panel (Fig. BACK 1 step 3). STEP 3 : Remove back panel and disconnect the ground cable from it (Fig. BACK 1 step 4 / BACK 2).
,., : \ _. :; , . I
B) Installation STEP 1: Connect ground cable to back panel, place the panel over the four screws (Fig. BACK 2 / BACK 1 step 4 & 3). Take care that the 4 drain tubes are not pinched behind the back panel !
STEP 2 : Let the backpanelslidedowngentlyoverthe screws (Fig.BACK 1 step2).

STEP 3 : Fasten the four screws (Fig. BACK 1 step 1).
129
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1 I 1
4 r
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Fig. : BACK 1
4.. 3,
Fig. BACK 2
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130
9.2.2. The top cover

WARNING : It takes TWO PEOPLE
transport system.
to safely remove and re-install the top cover. This will prevent causing damage to the flex cables or parts of the
A) Removal STEPl: STEP2: Remove the back panel (refer to par. 9.2.1. A). Remove the two screws at the rear of the top cover (Fig. TOP 2).
STEP 3 : Pull, and then turn a quarter turn (either clockwise or counter clockwise) the two knobs inside the top cover so that they remain in the out position (Fig. TOP 1). WARNING : STEP4:
Take care not to damage parts of the transport system or the flex cables while performing the next step.
0 ,:
Slightly lift the top cover at the rear, then move it a bit forward to clear it from the frame. Lift the top cover and remove it.
B) Installation
STEPl:
Pull, and then turn a quarter turn (either clockwise or counter clockwise the two locking knobs inside the top cover so that they remain in the out position (Fig. TOP 1).
Take care not to damage parts of the transport system or the flex cables while performing the next step.
WARNING :
STEP 2 : First place the front side of the top cover and align it with the frame, then lower the rear. Turn the locking knobs until they are drawn inside (Fig. TOP 2). STEP 3 : Partially insert the two screws at the rear as indicated in figure TOP 2. STEP4: Re-install the back panel (refer to par. 9.2.1. B).
t- -_) <..>;;
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Fig. : TOP 1
-
-.
Fig. TOP 2
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9.2.3. The front panel

A) Removal STEP 1: STEP2: Remove, at the front, all three liquid containers. Pull, and then turn a quarter turn (either clockwise or counter clockwise) the two knobs at the bottom of the front panel until they stay in the out position (Fig. FRONT 1). Grasp the bottom side of the panel and pull it forward to release it from the two hooks inside (Fig. FRONT 1). Then carefully slide the whole panel gently a little forward. Disconnect all cables from the ALERT board, which is mounted at the left inside the front panel (Fig. FRONT 4). Now remove the front panel.
STEP3:
STEP4:
B) Installation STEPl: Connect all cables to the ALERT board (Fig. FRONT 4). - the power supply cable - the cable to the alert outlet lug - the small flat cable coming P rom the input module Hold the panel with the bottom slightly tilted towards you. Place the panel in such a way that the two hooks inside the panel are positioned immediately above similar hooks inside the unit (Fig. FRONT 3). Then push the bottom of the panel forward until the panel fits properly. Turn the two knobs at the bottom of the panel until they are drawn inside (Fig. FRONT 3). Re-install the three liquid containers.
STEP2:
STEP3: STEP4:
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INSTRUCTIONS
-.
Fig. : FRONT 1
Fig. FRONT 2
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134
Fig. : FRONT 3
Fig. : FRONT 4
135
9.2.4. Left side panel

A) Removal STEPl: STEP2: Remove the back panel and the front panel (refer to par. 9.2.1. A and 9.2.3. A). Disconnect all cables from the rear connection panel.
STEP 3 : Unscrew the two sunken screws at the front and on the inside of the left frame plate (Fig. SIDE 1). STEP4: STEP5: STEP6: Hold the bottom of the panel and remove the two screws at the rear of the side panel (Fig. SIDE 2). Lower the side panel a little in order to clear it from the subframe. Disconnect the ground wire from the front of the panel (in front of the computer). Remove the left anel by moving it sideways. First remove the front and then the rear part P Fig. SIDE 6).
B) Installation STEPl: STEP2: STEP3: STEP4: STEP6: Place the left side panel in position. First place the rear and then the front part and connect the ground wire to the panel (Fig. SIDE 6). Lift up the anel so that it fits around the bottom bar of the subframe (Fig. SIDE 1P . Insert and lock the two sunken screws at the front and inside of the left frame plate (Fig. SIDE 1). Partially insert the bottom screw at the rear. Enough space should be left to place the back panel (Fig. SIDE 2). Fasten the top screw. Re-install the front and the back panel (refer to par. 9.2.3. B and 9.2.1. B).
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136
9.2.5. Right side panel

A) Removal STEPl: STEP2: Remove the back panel, the top cover and the front panel (refer to par. 9.2.1. A, 9.2.2. A and 9.2.3. A). Disconnect the wiring plugs from both reagent door cooling fans. Remove the screws which fasten the fans to the right panel and pullout both housings of the fans (Fig. SIDE 3). Unscrew the two sunken screws at the front and on the inside of the right frame plate (Fig. SIDE 4). Hold the bottom of the panel and remove the two screws at the rear of the side panel (Fig. SIDE 3). Lower the side panel a little in order to clear it from the subframe.
STEP3: STEP4: STEPS:
STEP 5 : Remove the right panel by moving it sideways, first the front and then the rear part (Fig. SIDE 5). B) Installation STEPl: STEP2: STEP3: Place the right side panel in position, first the rear and then the front part (Fig. SIDE 5). Lift up the panel so that it fits around the bottom bar of the subframe (Fig. SIDE 4). Insert and lock the two sunken screws at the front and inside of the right frame plate (Fig. SIDE 4).
STEP 4 : Partially insert the bottom screw at the rear. Enough space should be left to place the back panel (Fig. SIDE 3). Fasten the top screw. STEP5: STEP6: Install both reagent door cooling fans in right side panel. Fasten the fans and connect the wiring plugs (Fig. SIDE 3). Re-install the front panel, the top cover and the back panel. (refer to par. 9.2.3. B, 9.2.2. B and 9.2.1. B).
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Fig. : SIDE 1
/-,,
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&UC
--
Fig. SIDE 2
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Fig. : SIDE 3
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1 I I I I I I A I I II -_
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+; Sub frame
Fig. SIDE 4
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Fig. : SIDE 5
Fig. SIDE 6
9.2.6. The front sliding doors

A) Removal STEPl: It is not necessary but advised to first remove the front panel (refer to par. 9.2.3. A).
STEP 2 : Grasp the door at the bottom (Fig. DOOR 1 & 3). STEP 3 : Lift the front door out of the bottom groove and pull it forward (Fig. DOOR 1 & 3). STEP 4 : Take the door out of the upper groove (Fig. DOOR 2 & 4). STEP 5 : Repeat steps 2,3 and 4 for removal of the second door. REMARK : both sliding doors are identical ! B) Installation STEP 1: Place the door in the upper back groove (Fig. DOOR 4 & 3).
. f3
STEP 2 : Grasp the door at the bottom. Push it up slightly and position it over the back bottom groove, then insert it in the groove (Fig. DOOR 3). STEP 3 : Place the front door in the upper groove (Fig. DOOR 2 & 1). STEP4: Grasp the door at the bottom, push it up slightly and position it over the front bottom groove, then insert it in the groove (Fig. DOOR 1).
STEP 3 : If removed re-install the front bottom panel (refer to par, 9.2.3. B).
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141
Fig. : DOOR 1
Fig. DOOR 2
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142
f- ?, i.;.-:
Fig. : DOOR 3
Fig. DOOR 4
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143
9.3. Chemical modules 93.1. Incubator module
A) Removal of an Incubator module STEP 1: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
WARNING : Verzfi that the mains switch is indeed in the OFF position.
With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in tile MPP 3000 to power the computer system.
WARNING : If the plate carriage is positioned outside the module, push it gently back
inside to avoid causing mechanical damage while removing the module.
STEP 2 : Remove the back panel (refer to par. 9.2.1. A). WARNING : Observe ESD precautions ! STEP 3 : Disconnect the flat cable coming from the interface box on top of the MPP 3000, (Fig. INC 1 & 2) from the incubator module. STEP 4 : Unscrew and remove the four screws which fasten the module to the frame. STEP 5 : Pull out the module gently until the power supply cable is accessible. Disconnect the power supply cable from the Incubator board (Fig. INC 3). STEP6: STEP7: Pull out the module completely. Before storage or shipment, install the transport protection (refer to Fig. 4.19 in chapter installation) and pack the module properly. Use the transport protection and the packing materials from the spare part youre going to use.
B) Installation of an Incubator module WARNING : Observe ESD precautions ! STEP 1: Unpack the module and remove the transport protection (refer to Fig. 4.19 in chapter installation).
STEP 2 : Set the address jumpers properly (depending on the position of the module in the MPP 3000). If the module you install is incubator unit no 9, then transfer the two terminating resistor arrays from the module you have just removed.
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The board on which the jumper setting and installation of the terminating resistors must be done, is located on top of the module (Fig. INC 4). STEP 3 : Insert the module partially and connect the power supply cable (Fig. INC 3). STEP 4 : Insert the module fully and position it so that its carriage is located approximately in the middle of the window opening at the front (Fig. INC 3). STEP5: STEP6: STEP7: Fasten the module by means of the four screws at the rear. Connect the flat cable, coming from the interface box, to the module (Fig. INC 1 & 2). Verify that the module carria e is parallel (in X and Y plane) with the grab. Plate pickup or putdown di B ficulties can occur when the carriage is not parallel with the grab.
Verify or adjust X parallelism (front-rear) according to the following procedure : - The front part of the module should rest on the extruded profile. It should not be possible to push down the front part of the module (floating front). - If not correct, remove the incubator and remove the rear panel from the module (2 screws at the rear and one at each side). - Enlarge (using a file) the holes for the side screws (in the rear panel) more to the front. - Mount the rear panel on the module. Make sure that the angle between rear panel and bottom plate of the module is a little more than 90 degrees. - Mount and fasten the module in the MPP 3000 frame and check that the front of the module rest on the extruded profile. Verify or adjust Y parallelism (left-right) according to the following procedure (MPP 3000 must be switched off !) : - Pull the module carriage completely out and place the I/O adjustment tool plate on the carriage. - Gently lower the grab until one of the thumbs nearly touches the tool plate. - Check the tolerance (difference in visible air gap) between both thumbs and the tool plate, the difference should be as small as possible or at least less than 0.5 mm. - Loosen both screws that hold the black block at the front of the incubator module.
- Adjust the module carriage parallelism by tilting the black block. When correct
lock the black block with both screws. - Remove the tool plate and close the module carriage. STEP 8 : Install the back panel (refer to par. 9.2.1. B). The incubator module is now installed. Since it will be in a slightly different position than the previous module, it might be necessary to re-calibrate the module carriage position and the grab coordinates. Run the CALIBPOS service program and follow the instructions shown on the screen. After terminating this program, the proper coordinates of the newly installed Incubator module are stored. Refer to chapter Calibration for full details.
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-flat
cable
Fig. : INC 1
flat cable .
Fig. INC 2
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Fig. : INC 3
Fig. INC 4
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9.3.2. Washer module

A) Removal of the Washer module STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when tile mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
WARNING : Verify that the mains switch is indeed in the OFF position.
STEP 2 : Remove the back panel (refer to par. 9.2.1. A). WARNING : Always wear protective gloves, while carrying out step 3, to avoid getting
into contact with possibly infectious liquids !
STEP 3 : Remove the drain tubing from both dispense units and the washer module (Fig. WASH 1). The pump drain tubing remains fiied to the module. Remove all wash liquid tubing from washer module.
WARNING
: Respect ESD precautions !
STEP 4 : Disconnect, the flat cable coming from the interface box on top of the MPP 3000 (Fig. WASH 2) and the small flat cable next to it which comes from the wash liquid container units. STEP 5 : Unscrew and remove the four screws which fasten the module to the frame (Fig. WASH 3). WARNING : If the plate carriage is positioned outside the module, push it gently back
inside (only possible when the Z-mechanism is in the upper position) to avoid causing mechanical damage while removing the moduleSTEP6:
Pull back the Washer module until the power supply cable is accessible.
Disconnect the power supply cable (Fig. WASH 4).
STEP 7 : Gently pull out the module while taking care not to damage the power cable. STEP 8 : Before storage or shipment, install the transport protection. Use the transport protection from the spare part youre going to use Installing it must be carried out accordmg following procedure : WARNING : Carrying out the next steps is only possible when the Z-mechanism
upper position. If this is not the case, place it there manually rotating tile eccentric wheel. is in the by gently
A)
Remove the manifold by unscrewing the knurled knob (Fig. WASH 5).
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B)
Pull the plate carriage slightly forward. Slide the long transport bracket at the rear into the module from left to centre position and lock it with the cross-head screw (Fig. WASH 6). Gently push the plate carriage back in until it touches the just installed rear transport bracket. Place the front transport bracket and lock it using the two cross-head screws (Fig. WASH 6). Install the long plastic rod to lock the Z-mechanism (Fig. WASH 6). Mount the rear transport protection plate.
C)
D)
Pack the module and manifold properly. Use the package from the spare part youre going to use. B) Installation of the Washer module WARNING : Respect ESD precaution STEPl: A) B) C> D) STEP2:
!
Unpack the module and the manifold. Remove the transport protection according to the following procedure : Remove the rear transport protection plate. Unscrew the long plastic rod that locks the Z-mechanism. Unscrew and remove, while supporting the module carria e, the two screws that hold the front transport bracket, then remove bracket kFig. WASH 5). Unscrew and remove the screw that holds the rear transport bracket. Slide the bracket to the left and remove it (Fig. WASH 6). Install the manifold and fasten it with the knurled knob (Fig. WASH 5). Partially insert the module and connect the power supply cable (Fig. WASH 4). Check that the power supply cable can not interfere with the manifold drive system while inserting the module. Fully insert the module and position it so that the plate carriage is located approximately in the middle of the front window opening (Fig. WASH 4). Fasten the module with the four screws at the rear (Fig. WASH 3). Connect the flat cable coming from the interface box and the small flat cable coming from the liquid contamer modules (Fig. WASH 2). Connect all drain tubes to the washer and dispense (Fig. WASH 1). Secure the drain tubes with tye wraps Install the back panel (refer to par. 9.2.1. B). modules.
STEP3: STEP4:
STEP 5 :
STEP6: STEP7:
The washer module is now installed. Since it will be in a slightly different position than the previous module, it is necessary to re-calibrate the module carriage position and the grab coordinates. Change in ACT.all the MSCARRDIST value of the washer to 0 (zero). Run the CALIBPOS service program or Autocalibration from the main menu. After terminating this program, the proper coordinates for the newly installed washer module are stored. Refer to chapter Calibration for full details.
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Fig. : WASH
Fig. WASH
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9.3.2.1. Washer sub-modules

WARNING : Always wear protective gloves, while working on the washer module, to
avoid getting into contact with possibly infectious liquids !
A) Replacement of the dispense pump STEPl: Remove the washer module from the MPP 3000 (refer to par. 9.3.2. A).
STEP 2 : Remove the tubes from the in- and outlet valve of the dispense pump. STEP 3 : Disconnect the opto-interruptor flat cable from the power board (JlO). STEP4: STEP5: Unplug the stepping motor cable from the cable harness. Remove the four screws (accessible through the bottom plate of the washer module) that fasten the dispense pump to the pump frame plate.
$9.
-4
STEP 6 : Remove and discard the dispense pump. STEP 7 : Mount the new dispense pump and fasten it with the four screws. STEP 8 : Re-connect the motor cable to the cable harness and the opto-interruptor flatcable to the power board (JlO). STEP 9 : Connect the tube coming from the Ii uid selection valve to the lower nipple and the tubing coming from the mani4old to the upper nipple of the dispense pump* REMARK : the outlet nipple (valve) of the dispense pump has a larger body than the inlet nipple (valve). STEP 10 : Mount the washer module in the MPP 3000 (refer to par. 9.3.2. B) and check its functionality. B) Replacement of the vacuum pumn STEPl: Remove the washer module (refer to par. 9.3.2. A).
STEP 2 : Disconnect the tubing from both pump elbows and the tubing coming from the bottom of the aerosol filter. STEP 3 : Disconnect the sensor cable and the motor cable from the power board (58 and JS). STEP 4 : Remove the four screws (accessible through the bottom plate of the washer module) that fasten the vacuum pump to the pump frame plate. STEP 5 : Remove and discard the vacuum pump (with drain tube). STEP 6 : Mount the new vacuum pump (with drain tube) and fasten it with the four screws. STEP 7 : Connect the sensor cable and the motor cable to the power board (58, J5). STEP 8 : Connect the tubing to the elbows. Secure all tubes with tye wraps.
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STEP 9 : Mount the washer module in the MPP 3000 (refer to par. 9.3.2. B) and check its functionality. C) Replacement of the aerosol filter STEPl: STEP2: STEP3: STEP4: STEP5: STEP6: Remove the washer module (refer to par. 9.3.2. A). Disconnect the tubing from the elbow on top of the aerosol filter. Lift and remove the filter body from the washer module. Disconnect the tubing from bottom nipple and discard the aerosol filter. Connect the tubing to bottom nipple of the new aerosol filter and slide the filter body into the washer module. Connect the tubing to the elbow on top of the aerosol filter. Secure this tubing with a tye wrap. Mount the washer module in the MPP 3000 (refer to par. 9.3.2. B) and check its functionality.
L.
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93.3. Container unit

A) Removal of a container unit STEP 1 : If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable. WARNING : VenB that the mains switch is indeed in the OFF position.
H&h the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
STEP 2 : Remove the three liquid containers. STEP 3 : Remove the back panel and the front panel (refer to par. 9.2.1. A and 9.2.3. A)* STEP 4 : Mark the container unit positions on the MPP 3000 frame. Unscrew and remove the screws that hold the container units (Fig. CONT 1). WARNING : Respect ESD precautions ! STEP5: Disconnect the small flatcable from the rear of the washer module.
c-1
STEP 6 : Gently pull out all container units simultaneously. While doing this, gradually pull out the pipes connected to the container unit connectors (Fig. CONT 2). When accessible disconnect, the signal cable to the washer module from the left container module. STEP 7 : Pull out the container units fully and disconnect the small flat cables from the small board inside the module you want to replace (Fig. CONT 4). STEP 8 : Before storage or shipment, pack the module properly. packing material from the spare part youre going to use. Use the (yj
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B) Installation of a container unit WARNING : Respect ESD precautions ! STFPl: STEP2: STEP3: Unpack the container unit. Remove the two bottom sunken screws from the back of the module and tilt the back panel to create access to the small board inside (Fig. CONT 3). Set all jumpers on the board properly (refer to Fi . CONT 4). If the unit to er the terminating resistor be installed is no 3 (the rightmost unit), then trans B array from the old unit to the new one and put it exactly in the same position, meaning that the little dot on the resistor is positioned at the same side as the sloping line in the box drawn around the resistor connector on the board. (Fig. CONT 4).
STEP 4 : Fasten the back pane1 of the container unit. STEP5: Insert the container units partly and connect the flat cables interconnecting the boards at the rear of the units. Youll have to insert the cables into the units through the side slits.
STEP 6 : Fully insert the units and simultaneously insert the pipes in the receptacles of the modules. Hold the pipes and press them firmly in the receptacles. If necessary (for easier insertion) lubricate the outside of the pipes with a small amount of Vaseline (take care that no Vaseline enters the pipes). STEP7: Position the units in their original osition (refer to the marks on the frame) and fasten them with the screws P Fig. CONT 1). The modules must align with the windows for the liquid containers in the front panel. Install the front panel (refer to par. 9.2.3. B). Insert the liquid containers.
STEP 8 : STEP9:
STEP 10 : Connect flat cable to washer module.
156
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I
Fig. CONT 2
.*. -._- - ----
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Fig. CONT 4
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9.3.4. Dispense module

A) Removal of the dispense module (unper or lower)
STEPl:
If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when the tnains switch is in the ON position. Tllis means that there is mains voltage present in the MPP 3000 to power the computer system. . . c-3
WARNING : VeriY that the mains switch is indeed in the OFF position.
STEP 2 : Remove the back panel (refer to par. 9.2.1. A). WARNING : If the plate carriage tray is positioned outside the module, push it gently back
inside to avoid causing mechanical damage while removing the module.
WARNING : Always
wear protective gloves, while carrying out next step to avoid getting into contact with possibly infectious liquids !
STEP 3 : Open the reagent door (Fig. DISP 1). If this is impossible (the door is locked) carry out step 4, otherwise proceed with step 5. STEP 4 : Unlocking the reagent door requires placing the needle head of the reagent door in the park position (Fig. DISP 2) and positioning the pump drive motor fully backwards (Fig. DISP 3). This can be done using the PARK command of the Bitbus monitor (refer to chapter Troubleshooting). WARNING: Make sure the grab is not in front of one of the dispense modules ! REMARK : In case of complete malfunctioning of the dispense module, placing the needle head in the park position and/or positioning the pump drive motor fully backwards, must be done manually. The needle head can be accessed through the front window of the module, push the needle head fully to the right. By inserting a little hook (art. 08243) through the access hole, at the rear of the module, the door locking pin can be reached and pulled to unlock the door. Or, by inserting a long hook through the access hole, the pump drive motor can be caught and pulled back completely to unlock the reagent door. WARNING : Respect ESD precautions ! STEP 5 : Carefully disconnect the interconnecting flex cable coming from the reagent door (Fig. DISP 1). STEP 6 : Loosen the lock screw in the top left hand corner by first unlocking the nut and then the screw itself (Fig. DISP 3).
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STEP7:
Disconnect from the washer and the dispense module the flat cables coming from the interface box on top of the MPP 3000 (Fig. DISP 4).
STEP 8 : Loosen and remove the four screws at the rear of the module (Fig. DISP 5). STEP 9: Disconnect the drain tubing from the module drain port.
STEP 10 : Pull out the dispense module a little until the power supply connector is accessible (Fig. DISP 5). STEP 11: Disconnect the power supply connector (Fig. DISP 5). STEP 12: Before storage or shipment, re-install the transport protections : the two hexagonal screws to lock the carriage (Fig. DISP 6) and the rear protection plate. Pack the module properly, Use the transport protections and package from the spare part youre going to use. B) Installation of the disuense module (upper or lower) WARNING : Respect ESD precautions ! STEP 1: Unpack the dispense module and remove the transport protections. Dont for et to remove the two hexagonal screws which locks the carriage. Be f ore inserting the module, make sure the power supply cable 1scleared so that it wont get stuck while inserting the module. Also make sure the reagent door is open (Fig. DISP 5). Partially insert the module, (Fig. DISP 5). then connect the power supply cable
STEP2: STEP3:
Fully insert the module. Press it firmly against the frame plate and fasten it at the rear using the four screws (Fig. DISP 5). Fasten the lock screw in the top left hand corner and lock the screw with the nut (Fig. DISP 3).
STEP 4 : Connect the flat cable coming from the interface box on top of the MPP 3000 to the module. Re-connect the flat cable to the washer module (Fig. DISP 4).
STEP5:
Connect the interconnecting flex cable to the module (Fig. DISP 1).
Make (Fig. sure that the pump driver motor
coming
from
the
reagent
door
STJ3P6: STEP7: STEP8:
is positioned
fully
to the
rear
DISP 6).
Place the needle head of the reagent door in the park position (Fig. DISP 2). Close the reagent door. Connect the drain tubing and secure this tubin with a tye wrap. Re-install the back panel (refer to par. 9.2.1. BB.
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The Dispense module is now installed. Since it will be in a slightly different position than the previous module, it is necessary to re-calibrate the module carriage position and the grab coordinates. Change in the ACT.all file the MSCARRDIST value for this module to 0 (zero). Run the CALIBPOS service program or Autocalibration from the main menu. After terminating this program, the proper coordinates for the newly installed Dispense module are stored. Refer to chapter Calibration for full details. C) Removal of the disuense reagent door (uuper or lower) STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable. WARNING : Verify that the mains switch is indeed in the OFF position.
With the mains cable disconnected, the UPS (Uninterruptabie Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
STEP 2 : Remove the right side panel (refer to par. 9.2.4. A). STEP 3 : Open the reagent door. If this is impossible, carry out step 4. Otherwise proceed with step 5. STEP 4 : Unlockin the reagent door requires placing the needle head of the reagent door in t a e park position (Fig. REAG 3) and positioning the pump drive motor fully backwards (Fig. REAG 1). This can be done using the PARK command of the Bitbus monitor (refer to chapter Troubleshooting). WARNING: Make sure that the grab is not in front of one of the dispense modules ! REMARK : In case of complete malfunctioning of the dispense module, placing the needle head in the park position and/or positioning the pump drive motor fully backwards, must be done manually. The needle head can be accessed through the front window of the module, push the needle head fully to the right. By inserting a little hook (art. 08243) through the access hole, at the rear of the module, the door locking pin can be reached and pulled to unlock the door. Or, by inserting a long hook through the access hole, the pump drive motor can be caught and pulled back completely to unlock the reagent door. WARNING : Respect ESD precautions ! STEP5: Disconnect the interconnecting flex cable from the reagent door to the dispense module (Fig. REAG 1).
STEP 6 : Loosen and remove the two nuts that fasten the hinge to the frame plate. Remove the hinge with reagent door. (Fig. REAG 2). STEP 7 : Unlock the small hexagonal screw at the centre of the hinge body. Slide out the shaft and remove the hinge from the door. (Fig. REAGENT 4). STEP 8 : Before storage or shipment pack the door properly. You can use the packing material from the spare part youre going to use.
_-. t&
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D) Installation of the dispense reagent door (upper or lower) WARNING : Respect ESD precautions ! STEPl: STEP2: STEP3: STEP4: Unpack the reagent door. Transfer the removed hinge from the old to the new reagent door (Fig. REAGENT 4). Position the door with the hinge on the MPP 3000 and fasten it slightly using the two nuts. Connect the flex cable from the reagent door to the dispense module (Fig. REAGENT 1). The flex cable must be routed behind the small bar inside the hinge (Fig. REAG 4) Fasten the flex cable with self adhesive tape to the side panel. Slide the needle head to the park position (Fig. REAGENT 3) and close the reagent door Adjust the position (level) of the door until it closes without mechanical resistance, then firmly lock the nuts of the hinge. The door must easily close without being lifted or pushed down. Install the right side panel (refer to par. 9.2.4. B).
STEP5: STEP6: STEP7:
STEP8:
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Fig. : DISP 1
edk block
Fig. DISP 2
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.-
Fig. : DISP 3
Fig. DISP 4
. _ - - - -- -.II~.. .-.-.--... -1.__.-
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Fig. : DISP 5
Fig. DISP 6
., ,.,. _..
_-_--..----
.._.._. ..__---~
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Fig. : REAG
I.-------
Fig. REAG 2
_, ._ . ..__--. _- ._-- . . - _.._ --.- _-..----___-
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Needle blat
Fig. : REAG 3
Fig. REAG 4
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9.3.5. Reader module

A) Removal of the Reader module STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the A4PP 3000 to power the computer system.
WARNING : Venifu that the mains switch is indeed in the OFF position
STEP 2 : Remove the back panel (refer to par. 9.2.1. A). WARNING : If the plate camage or jilter tray is positioned outside the module, push it
gentry back inside to avoid causing mechanical the module. damage while removing
STEP3:
Disconnect the flat cable coming from the interface top of the MPP 3000 from the module. (Fig. READ 1).
box
on
STEP 4 : Unscrew and remove the six screws at the rear of the module (Fig. READ 2). WARNING : Respect ESD precautions ! STEP5: STEP6: STEP7: Pull the module partially out until the power supply cable is accessible. Disconnect the power supply cable (Fig. READ 3). Pull out the module completely. Pull out the filter tray consisting of two round bars. Note,the left one is thicker than the right one, at the front of the module. Loosen the locking ring on the left bar with an Hexagonal key of 3 mm. Remove the ring and all the filters.
STEP 8 : Before stora e or shipment, install the transport protection and pack the module and f ilters properly. In this case, the transport protection is a piece of foam that fits into the opening of the plate carriage tray and under the lamp assembly. Use the transport protection and packing material from the spare part youre going to use (Refer to Fig. 4.23). B) Installation of the Reader module WARNING : Respect ESD precautions ! STEP 1: A) B) Unpack the Reader module and the filters. Remove the transport protection and install the filters as follows: Pull out the filter tray. Loosen the locking ring on the left bar with an Hexagonal key of 3 mm and remove the ring. Slide the filters over the bars in following order : 405nm, 450nm, 492nm, 540nm, 620nm, 690nm, (Fig. READ 4).
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C>
Lock the filters by means of the locking ring and push the filter tray back into the module. Before inserting the module, make sure that the power supply cable is clear so that it wont get stuck while inserting the reader module. Partially insert the module and connect the power supply cable (Fig. READ 3).
STEP2: STEP3:
STEP 4 : Insert the module fully and position it so that the carriage is located approximately in the middle of the window opening at the front (Frg. READ 2). STEP 5 : Fasten the module using six screws at the rear (Fig. READ 2). STEP6: STEP7: Connect the flat cable from the interface box on top of the MPP 3000 to the module (Fig. READ 1). Re-install the back panel (refer to par. 9.2.1. B).
STEP 8 : The filter setting must be stored in the memory of the new reader module. Activate the Unix BBM and type : do setfilters <enter >. Upon the last command executed the reply on the screen should show the following data line : 95 01 C2 01 EC 01 1C 02 6C 02 B2 02 00 00 00 00 Enter quit to exit the Bitbus monitor. The reader module is now installed. Since it will be in a slightly different position than the previous module, it is necessary to re-calibrate the module carriage position and the grab coordinates. Change in the ACT.all file the MSCARRDIST value for the reader to 0 (zero). Run the CALIBPOS service program or Autocalibration from the main menu. After terminating this program, the proper coordinates for the newly installed reader module are stored. Refer to chapter Calibration for full details.
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flat cable
Fig. : READ
Fig. READ
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Fig. : READ
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Fig. READ 4
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9.4. Transport
modules
9.4.1. Input / Output module

A) Removal of the Inout (or outnut) module STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
WARNING : Verijj that the mains switch is indeed in the OFF position.
STEP 2 : Remove the front panel (refer to par. 9.2.3. A). STEP3: Unscrew and remove the four phillips screws at the front of the module (Fig. I/O 1).
WARNING : Respect ESD precautions ! STEP 4 : Pull the module partially out and disconnect all cables from the board at the rear of the module (Fig. I/O 2 & 3). The rear of the module is accessible through the window above it. A) Innut module 1 The small flat cable at the left side rear (54, to the alert board). 2 The large flat cable (Jl, internal interface bus). 3I The power supply cable (33). B) Output module 1 The large flat cable (Jl, internal interface bus). 2 The power supply cable (53). 3 The small sensor cable (J5, from the temperature sensor of the storage area). STEP5: STEP6: Slide out the module carefully. Before storage or shipment, install the transport protection (a bushing with a screw in it) and pack the module properly. Use the transport protection and package from the spare part youre going to use.
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B) Installation of the InDut (or output) module WARNING : Respect ESD precautions ! STEP 1: First set the correct jumper settings on the board (Fig. I/O 3). When replacing an output module transfer the resistor arrays (3 pieces) from the removed module. Place them in exactly the same position, meaning that the little dot on the resistor is positioned at the same side as the sloping line in the box drawn around the resistor connector on the board. (Fig. I/O 4).
STEP 2 : Insert the module partially and connect the cables. Refer to the removal procedure step 4 for details about the cables (Fig. I/O 2 & 3). Using a dentists mirror makes it easier to connect the cables to the module. STEP 3 : Fully insert the module Take care not to damage the motor wiring on top of the board, or crimp the wiring of the temperature sensor on the output module . Then insert and lock the four screws at the front. (Fig. I/O 1). STEP 4 : Remove the transport protection inside the module (Fig. 4.18). STEP 5 : Adjust the position of the pins on the plate carriage by using the. following procedure : activate the Untx BBM and enter the followmg mstructlons :
tmsg 4 7 200t (to initialize the input module). tmsg 4 8 203t 1 (to move up the carriage from the input module).
FLsg 4 7 205t (to initialize the output module). tmsg 4 8 20% 1 (to move up the carriage from the output module). The carriage is now in the up position. Loosen the small screws next to the pins Place the tool plate on the carriage (Fig. I/O 4). Adjust the pins position until the tool plate is central with respect to the window sides. Again fasten the positioning pins with the small screws
tmsg 4 7 204t (to move down the carriage from the input module) tmsg 4 7 209t (to move down the carriage from the output module)
Repeat these actions a few times to check whether the tool plate does not hit the window sides. If it does, adjust and check again until the tool plate is properly positioned. Remove the tool plate. Enter quit to exit the Bitbus monitor. STEP 6 : Re-install the front panel (refer to par. 9.2.3. B). Verify that the carriage, when moving out, can open the door and does not hit the front panel. Check that the small pusher block is present at the front of the module carriage system. If not then remove this piece from the old module and glue it on the new module.
.
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Fig. : I/O 1
Fig. I/O 2
..I_. _ __--_-.--..--_..--.-...-. -
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Plllw
Fig. : I/O 3
. Fig. I/O 4 -
---_.- -..-.-- .--.
-11--
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9.4.2. Transport
positioner
A) Removal of the Transport positioner module STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Unintermptable Power Supply) will be activated when tile mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
WARNING : Vet-@ that the mains switch is indeed in the OFF position.
STEP 2 : Remove the top cover.(refer to par. 9.2.2. A). STEP 3 : Remove the bottom front panel and the sliding doors (refer to par. 9.2.3. A, and 9.2.5. A). STEP 4 : Remove both side panels.(refer to par. 9.2.4. A). WARNING : Respect ESD precautions ! STEP5: Loosen the four screws that fasten the Y drive motor to the frame plate. Then slide the motor to the front until the toothed belt can be removed (Fig. TRANS 1). Remove the grab (refer to par. 9.4.3. A).
STEP6:
STEP 7 : Disconnect both flat cables from the interconnecting board (Fig. TRANS 2). STEPS: STEP9: Unscrew and remove the bolts from the shaft holders, at the left and right sides of the frame (Fig. TRANS 3). Lift up and remove the transport positioner assembly (Fig. TRANS 4).
STEP 10: Before storage or shipment, re-install the cover on the vertical shafts and pack the transport positioner properly. Use the packing material from the spare part youre going to use (the transport positioner is fastened on a wooden plate).
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B) Installation of the TransDort Dositioner module WARNING : Respect ESD precautions ! STEPl: STEP2: STEP3: STEP4: STEP5: Unpack the transport positioner. Remove the cover from the vertical shafts for This cover is fastened with three screws at the top and bottom. Remove, using a dry cloth, the protective grease from all shafts. Remove the transport positioner from the wooden plate. Insert the transport positioner in the MPP 3000 frame. (Fig. TRANS 4). Take care that the left shaft holder does not fall off. the grab.
STEP 6 : Position the bottom guide block bearing around the bottom guide shaft (Fig. TRANS 5). STEP 7 : Slide the Y-movement mechanism of the transport positioner almost fully to the right. Insert and lock the shaft holder with the four bolts. (Fig. TRANS 6). STEP8: STEP9: Repeat step 7 for the left side (Fig. TRANS 7). Re-install the toothed belt and fasten the four screws that hold the Y drive motor. The belt tension should be adjusted by shifting the Y drive motor. If the belt is pulled up between 2,7 - 2.9 mm, then the tension measured with a dynamometer should be within 130 - 210 gram. The point of application must be chosen somewhere in the middle of the belt as indicated on Fig. TRANS 8.
STEP 10 : Connect the flat cables to the interconnecting board (Fig. TRANS 2). STEPll: Re-install the grab (refer to par. 9.4.3. B).
STEP 12: Re-calibrate the parallelism of the grab (as described in par. 9.4.3. B). STEP 13: Re-install all panels and the sliding doors. (refer to the procedures in par. 9.2). The transport positioner module is now installed. It is now necessary to recalibrate all position coordinates since all sensors will be in a slightly different position than those from the previous module, . Run the CALPOSAL calibration program and follow the instructions shown on the screen. After terminating this program, the proper coordinates for all module positions are stored. Refer to chapter Calibration for full details.
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Fig. : TRANS 1
Fig. TRANS 2
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Fig. : TRANS 3
-_._-
Fig. TRANS 4
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Fig. : TRANS 5
T
-/
I ,
Fig. TRANS 6
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Fig. : TRANS 7
Fig. TFtANS 8
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9.4.3. The Grab

A) Removal of the Grab STEP 1: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
WARNING : VenB that the mains switch is indeed in the OFF position.
With the mains cable disconnected, the UPS (Unintermptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
STEP 2 : Remove the top cover and the sliding doors (refer to par. 9.2.2. A and 9.2.5. A). WARNING : Respect ESD precautions ! STEP 3 : Unscrew and remove all screws (three at the bottom and three at the top) from the cover for the vertical shafts of the transport positioner. STEP 4 : Place the grab in its upper position and remove the cover (Fig. GRAB 1). Beware not to damage the flex cable inside the cover. STEP 5 : Place the grab in a more down position. STEP 6 : Unscrew and remove the four sunken screws (two on the left and two on the right) that hold the grab cover. Remove the grab cover (Fig. GRAB 2). STEP7: Disconnect the flat cable located at the front of the grab (Fig. GRAB 1).
STEP 8 : While holding the grab, unscrew and remove the two hexagonal screws that attach the grab to the transport positioner (Fig. GRAB 2). Remove the grab. STEP 9 : Before storage or shipment, re-install the cover of the grab and pack the grab properly in an anti-static bag. Use the packing material from the spare part youre going to use. B) Installation of the Grab WARNING : Respect ESD precautions ! STEPl: STEP2: STEP3: Unpack the grab. Unscrew and remove the four sunken screws (two on the left and two on the right) that hold the grab cover. Remove the grab cover (Fig. GRAB 2). Slide the z-movement part of the transport positioner to middle position.
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(-3 \ .T
STEP 4 : Place the grab and lock it slightly by means of the two hexagonal screws (Fig. GRAB 2) then position it horizontally and adjust the square setting according to the following procedure : 1 Place the grab down at the plate storage positions (Fig. GRAB 3 step 1). 21 Observe the air gap between both thumbs (left and right) and the bottom plate. TX-Y to make this air gap as equal as possible by tilting the grab. (Fig. GRAB 3 step 2). 3) When parallelism 1sreached then secure the hexagonal screws tightly. (Fig. GRAB 3 step 3). STEP 5 : Connect the flat cable at the front of the grab (Fig. GRAB 1). STEP 6 : The grab should also be perpendicular with respect to the plate input/output windows. To set this, load the grab with a plate carrier. Insert manually the rab with the plate carrier in the plate output window and manoeuvre $torque) the two vertical shafts of the transporter until the plate carrier in the grab is perpendicular with the window. (Fig. GRAB 4 step 1) If necessary unlock the four nuts that hold the window frame and adjust the position and parallelism of the window with the grab (Fig. GRAB 4 step 2). Fasten the nuts from the window frame (Fig. GRAB 4 step 3) Repeat previous steps for the input window. NOTE : The plate carrier in the grab should not move any direction (y or x) while lowered in the input or output window or on the storage positions. For inspection or fine tuning you can also monitor the change of the grab sensor values using the following procedure : - Activate the Unix BBM and type 200 do windowset <enter >. - The grab sensors values are now displayed at 1 second intervals. The data line looks as follows : bb bb bb bb bb bb bb bb yy yy xx xx bb bb. Where bb are not relevant bytes, yy the Y and xx the X are deflection sensor values. - By lowering the grab, holding a plate carrier, into a window or on the storage then the grab sensor values should not change. - Adjust (torque) the vertical shafts of the transporter for minimal change of the Y deflection sensor values (Fi . GRAB 4 step 1). - Adjust position o Bthe input/output window and storage module for minimal change of the X deflection sensor values (Fig. GRAB 4 step 2). - Enter quit to exit the BBM. STEP 7 : Re-install the grab cover (Fig. GRAB 2). STEP 8 : Place the grab in its upper position and re-install the cover that covers the vertical shafts (Fig. GRAB 1). While doing so, gently guide the flex cable into the cover. the sliding doors STEP 9 : Re-install (refer to par. 9.2.2. B and 9.2.5. B). and the top cover
c3
I 0:
If a new grab is installed, then the sensor values will differ from the original grab. If it is necessary to re-calibrate it. Run the TptCal calibration program and follow the instructions shown on the screen. After terminating this program, the proper sensor values of the newly installed grab are stored. Refer to chapter Calibration for full details. Verify operation by running CALPOSAL or Autocalibration.
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Fig. : GRAB 1
Fig. GRAB 2
_ I
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c-4
Fig. : GRAB 3 -
Fig. GRAB 4
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9.4.4. Position and / or Motor Control board

A) Removal of the oosition and / or motor control board STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Uninterruptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
WARNING : Veri! that the mains switch is indeed in the OFF position.
STEP 2 : Remove the back, front and right side panel (refer to par. 9.2.1. A, 9.2.3. A and 9.2.4. A). WARNING : Respect ESD precautions ! STEP 3 : Remove all screws that hold the cover of the board box and remove the cover. Take care not to damage the two flex cables from the transporter. (Fig. POS 1). STEP 4 : Disconnect the filter board with the flex cables from the position board. (Fig. POS 1). STEP5: Disconnect all cables from the motor control board. Unscrew and remove the 4 screws that hold the board. Remove the board (Fig. POS 2). or Disconnect all cables from the position control board. Unscrew and remove the 6 screws that hold the board. Remove the board (Fig. POS 2).
REMARK 1 : Remove the EPROM, IC 4, from the position control board. (Fig. POS 3). A new board is always delivered without EPROM. REMARK 2 : Do not return the motor control boards for repair, discard them. The position control boards can de returned.
..,. -__
._-
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B) Installation of the position and / or motor control board WARNING : Respect ESD precautions ! STEP 1 : Unpack the board. STEP 2 : Install the board. Fasten the motor control board with the 4 screws (Fig. POS 2). Fasten the position control board with the 6 screws (Fig. POS 2). NOTE : The position control board is delivered without EPROM. Transfer the EPROM, IC 4, to the new board. (Fig. POS 3) STEP 3 : Connect all cables to the board. STEP 4 : Connect the filter board with flex cables to position board. (Fig. POS 1). STEP 5 : Re-install the cover plate on the board box and fasten all screws. Take care not to damage or disconnect the two flex cables from the transporter (Fig. POS 1). STEP 6 : Re-install the right side panel, the front panel and the back panel (refer to par. 9.2.4. B, 9.2.3. B and 9.2.1. B).
c \
-. 9
-. _.. .._-_ I _ _..-..-_---_-l-,-
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Fig. : POS 1
Fig. POS 2
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Fig. : POS 3
. . .._ .) . ..I.~... .--__I
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9.4.5. Label decoder board

A) Removal of the label decoder board STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when tile mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer Jystem.
WARNING : Veri that the mains switch is indeed in the OFF position.
STEP2:
Remove the back panel, front panel and right side panel. (refer to par. 9.2.1. A, 9.2.3. A and 9.2.4. A).
WARNING : Respect ESD precautions ! STEP 3 : Remove all screws that hold the cover of the board box and remove the cover. Take care not to damage the two flex cables from the transporter. (Fig. LAB 1). STEP4: Disconnect all wiring from the label decoder board. Unscrew and remove the 4 screws that hold the board. Remove the board (Fig. LAB 2). Beware not to loose the extra spacers under the board since they are absolutely necessary to isolate the board from the metal frame. Before storage or shipment, pack the board properly in an anti-static bag. Use the packing material from the spare part youre going to use.
STEP5:
B) Installation of the label decoder board WARNING : Respect ESD precautions ! STEPl: STEP2: STEP3: Unpack the board. Check and if necessary correct the jumper settings (Fig. LAB 3). When necessary fasten the watchdog board with silicone kit (Fig. LAB 3).
STEP 4 : Install the label decoder board. Fasten the board with the 4 screws (Fig. LAB 2). Do not forget the extra spacers under the board since they are absolutely necessary to isolate the board from the metal frame. STEP 5 : Connect all wires properly. STEP 6 : Check calibration (refer to procedure in Fig. LAB 4). STEP 7 : Re-install the cover plate on the board box and fasten all screws. Take care not to damage or disconnect the two flex cables from the transporter. (Fig. POS 1). STEP8:
._I -... --.. ,. ..._. -. _II . . . .._-..__ _I_
Re-install the right side panel, the front panel and the back panel (refer to par. 9.2.4. B, 9.2.3. B and 9.2.1. B).
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Fig. : LAB 1
Fig. LAB 2
..__ _ _.^___ _ ___. --.____..__ --.
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PROCESSOR j
Fig. : LAB 3
-Ex
Fig. L.AE3 4
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9.5. Power Supplies 9.5.1. The UPS (Uninterruptable Power Supply)
A) Removal of the UPS KJninterruDtable Power SLIDD~V) STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
With the mains cable disconnected, the UPS (Unintermptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the A4PP 3000 to power tile computer system.
WARNING : Veri that tile mains switch is indeed in the OFF position.
WARNING : Respect ESD precautions ! STEP 2 : Remove the back panel (refer to par. 9.2.1. A). STEP 3 : First remove (for safety reasons) the two violet wires from the bottom of the connector located at the rear of the UPS module, indicated with CONTR. SW. Then disconnect the other wires from that connector (Fig. UPS 2). STEP 4 : Disconnect the cable coming out of the UPS from the connector block (Fig. UPS 2). STEP 5 : Unscrew and remove the 10 screws that lock the UPS (Fig. UPS 1). STEP 6 : Remove the ventilation guide, then clear the drain tubings and pull out the UPS. STEP 7 : Before storage or shipment, pack the module properly (anti static). Use the packing materials of the spare part youre going to use.
---.
--.. --.-.
.- ,____.._._ -
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B) Installation of the UPS (Uninterruptable Power Supplv)

WARNING : Respect ESD precautions !
STEPl: STEP2:
Unpack the module. Verify that the voltage and frequency of the new UPS module matches the provided mains power conditions.
: Check that the mains switch is in the off position disconnected before starting the installation ! and the mains cable is
WARNING
STEP3: STEP4: STEP5:
Insert the module in the MPP 3000 frame. Install the ventilation guide and fasten the UPS with the ten screws at the rear. (Fig. UPS 1). Connect the wires from the cable coming out of the UPS, as indicated on Fig. UPS 2. Connect the three upper wires to the connector on the rear of the UPS. Lastly, connect the two bottom violet wires to the connector indicated with CONTR. SW (Fig. UPS 2).
STEP 6 : Re-install the back panel (refer to par, 9.2.1. B). STEP 7 : Verify the functionality of the new UPS module : Switch on the MPP 3000 unit while the power cord is not and should boot connected to the mains. The computer every 30 seconds a beep should be generated by the UPS. Connect the MPP 3000 to the mains, the UPS should now stop beeping. REMARK : In case the UPS generates a intermittend short beep, or does not work at all, then this might be caused by unloaded batteries. Connect the MPP 3000 to the mains power and switch on for some hours. Disconnect the power cable from the mains to check the functionality of the UPS. (refer to step 7 above).
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Fig. : UPS 1
Fig. UPS 2
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9.52. The +SVolt and +/-15Volt
Power Supply
A) Removal of the + SVolt and + /-15Volt Power SUPPI~ STEP 1: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
WARNING : Vet-@ that the mains switch is indeed in the OFF position.
With the mains cable disconnected, the UPS (Unintenuptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the MPP 3000 to power the computer system.
WARNING : Respect ESD precautions ! STEP 2 : Remove the back panel (refer to par. 9.2.1. A). STEP 3 : Disconnect the wiring at the rear of the module (Fig. SVOLT 2). STEP 4 : Unscrew and remove the four screws that hold the module (Fig. SVOLT 1). STEP 5 : Pull out the power supply module. STEP 6 : Remove the housing from the module (Fig. SVOLT 3). REMARK : Do not return this module for repair but discard it B) Installation of the +SVolt and + /-15Volt Power SUPP~V WARNING : Respect ESD precautions ! STEPl: STEP2: Unpack the power supply module. Verify that the voltage setting of the new power supply module matches the provided mains power conditions. Set, when necessary, the selection wire to the correct input mains voltage (220V or 1lOV, refer to Fig. SVOLT 2). Connect a load resistor (1 Ohm/l0 Watt) drawing 5A and a multimeter (range 1OV DC) to the power supply as indicated on Fig. SVOLT 4. Apply the proper mains voltage and when necessary adjust the output voltage between 5,2V and 5,25V DC. Mount the power supply in the housing (Fig. SVOLT 3). Insert the module in the MPP 3000 frame (Fig SVOLT 1).
STEP 3 :
STEP4: STEP5:
STEP 6 : Fasten the module by means of the four screws (Fig. SVOLT 1). STEP 7 : Connect the wiring as indicated in Fig. SVOLT 2. STEP 8 : Re-install the back panel (refer to par. 9.2.1. B).
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Fig. : SVOLT
I eJ 1
+WAW. 83 AUXOUTWlrrU.
Fig. SVOLT 2
( ; ::. :d
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Fig. : SVOLT 3
Fig. SVOLT 4
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9.5.3. The + 24Volt Power Supply

A) Removal of the +24Volt Power SUDDI~ STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
WARNING : Ven$ that the mains switch is indeed in the OFF position. With the mains cable disconnected, the UPS (Unintemsptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltage present in the h4PP 3000 to power the computer system.
WARNING : RespectESD precautions ! STEP2: Remove the back panel, the top cover and the left side panel. (refer to par. 9.2.1. A, 9.2.2. A and 9.2.4. A).
STEP 3 : Disconnect the wiring from the power supply (Fig. 24VOLT 3). STEP 4 : Unscrew and remove the 8 screws at the rear of the module (Fig. 24VOLT 1). STEP 5 : Pull out the module from the MPP 3000 frame STEP6: Remove the rear plate which is attached to the module (Fig. 24VOLT 2).
STEP 7 : Before storage or shipment, pack the PSU properly (anti static). Use the packing material of the spare part youre going to use.
.. I -.;. 9: i $2
_.-. . -. ..- -_-...._ .--.. - . . -..--_~
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B) Installation of the +24Volt Power SUDDI~ WARNING : Respect ESD precautions ! STEPl: STEP2: Unpack the power supply. Set the jumper for the proper mains input voltage : Install a bridge between A and B for 120V AC operation or install a bridge between B and C for 220V AC operation (Fig 24VOLT 3) Connect a load drawing 5A and a multimeter (range 30V DC) to the power supply as indicated on Fig. 24VOLT 4. Apply the proper mains voltage and when necessary adjust the output voltage between 25,2V and 25,25V DC. Remove the protective grid from the fan.
STEP3:
STEP4:
STEP 5 : Attach the rear plate to the new power supply as indicated in Fig. 24VOLT 2. Attention : distance A > B, otherwise the holes in the plate are not properly positioned when the module is inserted in the MPP 3000). STEP 6 : Insert the module and fasten it by means of the 8 screws (Fig. 24VOLT 1). STEP 7 : Connect the wiring as indicated in Fig. 24VOLT 3. STEP8: Re-install the panels. (refer to par. 9.2.4. B, 9.2.2. B and 9.2.1. B).
._~ --
.---- --
..----l-_--
--.
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Fig. : 24VOLT 1
Fig. 24VOLT 2
.. ._ _
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Fig. : 24VOLT 3
Fig. 24VOLT 4
._._
-_._,.-
--
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9.6. The Control System 9.6.1. The Computer

A) Removal of the Computer STEP 1: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
WARNING : Verify that the mains switch is indeed in the OFF position. U&h the mains cable disconnected, the UPS (Unintermptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltagepresent in the MPP 3000 to power the computer system. STEP 2 : Remove the back panel, the top cover and left side panel. (refer to par. 9.2.1. A, 9.2.2. A and 9.2.4. A). WARNING : RespectESD precautions ! STEP 3 : Disconnect all cables from the rear of the computer. Some cable connectors are locked with two screws. ( Fig. COMP 4). STEP 4 : Unscrew and remove the screws of the upper holder plate. Now remove the holder plate (Fig. COMP 1). STEP 5 : Remove the computer from its bottom holder (Fig. COMP 2). STEP 6 : Open the computer by removing the four screws at the rear (Fig COMP 4). Slide the top cover a little forward and lift it to remove. WARNING : RespectESD precautions ! STEP 7 : Remove the Bitbus interface board. (Fig. COMP 3). STEP 8 : Remove the Ethernet board. STEP 9 : Close again the computer housing. STEP 10 : Before storage or shipment, pack the computer properly. Use the packing material of the spare part youre going to use. B) Installation of the Comnuter WARNING : RespectESD precautions ! STEP 1 : Unpack the computer. Open the computer by removing the four screws at the rear (Fig COMP 4). Slide the top cover a little forward and lift it to remove. REMARK : Installation instructions for options are described in the included documentation provided with the computer.
. _ ...-..-.__---..-.-.-. --_.
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STEP 2 : Install and fix the Ethernet board in the lowest position. STEP3: STEP4: STEP5: STEP6: STEP7: STEP8: Install and fix the Bitbus interface board above the Ethernet board. Close again the computer housing. Put the computer in the bottom holder (Fig. COMP 2). Place the upper holder and lock it with the three screws (Fig. COMP 1). Connect all cables at the rear of the computer (Fig. COMP 4). Lock the connectors with the provided screws. Re-install the left side panel, the top cover and back pane1 . (refer to par. 9.2.4. B, 9.2.2. B and 9.2.1. B).
C) Hard drive of the computer REMARK : The hard drive in the new computer is not yet configered for Unix ! This new hard drive must be loaded with Unix and the MPP 3000 application software. Refer to the software installation procedures in the Installation chapter. Then a complete calibration must be performed to set the values in the ACT-all file. Run Autocalibration or CALPOSAL. Users protocols must be generated again. Only when you are sure that the hard drive in the defective computer is still OK ou can transfer this hard drive to the new computer. This eliminates a new installation o r all the software. In this case put the new hard drive in the defective computer before shipment for repair
.__...--..-
- .-- _--. -.--~-
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Fig. : COMP 1
//
Fig. COMP 2
. - .__, I_--I
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JUMPER
SETTING
........
.........
..
. .
..
. .
l fzJ . .
Fig. : COMP 3
\\ h
I I
J ,
5 6
Fig. COMP 4
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,- _.. 5, c. .
9.6.2. Internal Controller
boards
A) Removal of an internal controller board STEPl: If the MPP 3000 is switched ON, first perform a complete Unix shutdown procedure, then switch off the MPP 3000 and disconnect the mains cable.
WARNING : Verify that the mains switch is indeed in the OFF position. with the mains cable disconnected, the UPS (Unintemcptable Power Supply) will be activated when the mains switch is in the ON position. This means that there is mains voltagepresent in the MPP 3000 to power the computer system. STEP 2 : Remove the top cover (refer to par. 9.2.2. A). For access to the transport internal controller board, the right side panel must also be removed (refer to par. 9.2.4. A). REMARK 1 : There exists two different types of internal controller boards. A stri ped version which is used for the washer, reader and dispense modules. A completely illed up version (HCT type) is used for the incubators and the transport system.
REMARK 2 : A spare part internal controller boards is always delivered without EPROM. REMARK 3 : There are six internal controller boards. Five of them, are the incubator, washer, upper dispense, lower dispense and reader internal controller boards. They are mounted m a box in the upper part of the MPP 3000. The internal controller board for the transport is mounted in a box at the right frame plate, just under the reagent doors. STEP 3 : Remove all the screws from the top cover. Remove the cover from the box. (Fig. INT 1). WARNING : RespectESD precautions ! STEP 4 : Disconnect all cables (power supply cable, bitbus cables, bus flatcable) from the board that must be exchanged. STEP 5 : Remove the EPROM, IC 3, from the board (Fig. INT 2). STEP6: REMARK panel. Remove the two screws on the connector side of the board. Remove the c-2
boardby slidingit overthe holderclips.

: The transport internal controller board is mounted in a box on the right side
STEP 7 : Remove all screws that hold the cover of the board box and remove the cover. Take care not to damage the two flex cables from the transporter. (Fig. INT 3). STEP 8 : Disconnect all cables (power supply cable, bitbus cable, bitbus terminating resistor plug, bus flatcable) from the board (Fig INT 5) STEP 9 : Remove the EPROM, IC 3, from the board (Fig. INT 5). STEP 10 : Remove the four screws that hold the board and remove board.
; :. \ -3
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STEP 11 : Before storage or shipment, pack the board properly (in an anti-static bag). Use the packing material of the spare part youre going to use. B) Installation of an internal controller board WARNING : Respect ESD precautions ! STEPl: STEP2: Unpack the board. Insert the EPROM, IC3 ( removed from the old board) (Fig. INT 2 or Fig INT 5).
STEP 3 : Set the node code with Dip switch SW1 refer to Fig. INT 7. Refer to Fig INT 6 for the transport system node setting. STEP4: Set all jumpers, J3,55,56 and J8, properly (refer to Fig. INT 6).
STEP 5 : Install the board by sliding it over the holder clips and fasten it with the two screws. STEP6: Connect all cables back to the board. Do not forget to connect the bus terminator connector of the transport internal controller board. Re-install the box cover (refer to Fig. INT 1 or INT 3). Re-install the panels (refer to par. 9.2.2. B or par. 9.2.4. B).
STEP7: STEP8:
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no 1
Fig. : INT 1
Fig. INT 2
-I_ __. ._ _.._ _--....I-~ ____. _..-... -. ---.
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Fig. : INT 3
Fig. INT 4
_._
.--.~-- ..-- -__
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Fig. : INT 5
Fig. INT 6
_. --- .--.
.~.. -.-i_- .__
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SrnInG 3
1 L 2 - ON (1) 3 t,. 8
on
(0,
SFmINC 1
1 1 t/r
- ON (1) 8
or?
(0)
YASIER
SnTIWG 1
- 0 (1) 2 1 1 3 t/m a
on
(0)
smxnc.
4 - on (1) -1 t,. 3 5 t/m a - on (0)

lLl-am(l) -2 1 4 t/m
llT?ImS
- 011
(0)
Fig. : INT 7
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SPARE PART INFORMATION
213
10. Spare Part Information

This chapter provides the following information : Teknika Code : = computer reference information. Description : = the name or a short description of the spare part. Recstock : = the recommended stock level when 1 to 5 MPP 3000 units are installed in the field Trade-in parts are parts which have been in usage, repaired, checked and released by the original manufacturer, based on the same functional quality criteria as for original new parts. These parts are functionally identical to new parts but, they can show small indications of usage. Trade-in parts are provided at a much lower transfer price than those for new spare parts. Only those parts and tools mentioned in this spare part list can be procured. Some spare parts will have transport protections installed. These protections must be reinstalled on parts which you want to return to Organon Teknika. Returned parts must also be packed correctly, so whenever possible re-use the original packaging materials. Neglecting this may lead to a total loss of the returned spare part and will create additional charges. Missing packaging items can be ordered on special request, refer to the list of packaging materials in this chapter. REMARK : Parts which have been in usage inside the MPP 3000 system must first be disinfected (using the Box Disinfection Method) before returning them to Organon Teknika for repair.
TEKNIKA
CODE :
DESCRIPTION : REC.STOCK :
Sales nackapes 00167 00168 Accessories 08205 08277 08278 08279 08466 80257 80258 80259 08515 Various 06956 07175 08255 08281 08480 07236 08359 07624 08467 08207 08208 08743
ODtions
Sales package MPP 3000 version 220V / 50Hz (for contents refer to chapter Installation) Sales package MPP 3000 version 120V / 60Hz (for contents refer to chapter Installation)
Set (10 PCS) of plate carriers, Standard (colour black) Set (10 PCS) of plate carriers, Dynatech R (colour green) Set (10 PCS) of plate carriers, Nunc F/C (colour bleu) Set (10 PCS) of plate carriers, Nunc U (colour red) Set (60 PCS) of dispense disposables Kit (180 PCS) of 50ml reagent containers Kit (108 PCS) of lOOm1reagent containers Kit (56 PCS) of 200ml reagent containers Set (10 PCS) cleaning tools for incubator modules
Workstation keyboard UK Workstation keyboard US Mouse, serial version Barcode scanner EVGA colour display 15 MPP 3000 Control Software SC0 UNIX Open Desktop Operating manual Lubrication oil ACCU Lube box of 10 fuses 8A 5x20mm box of 10 fuses 15A 6.4x32mm Set of service cards
07265 07398 07330
Set of transparent sliding doors Liquid container Filter 650nm
215
TEKNIKA
CODE :
DESCRIPTION REC.STOCK :
Soare Darts
General 07602 07622 07623 Tube coupler Transportation bolt Table wheel set (4 pc) Power modules 07151 07154 07189 07203 07158 07159 Power supply 5V +/-15V Power supply 24V 40A UPS 220V / 50Hz UPS 120v / 60Hz Power cord assy 220V Power cord assy 120V Transport modules 08304 08352 08303 07297 07299 08302 07424 Plate Input or Output Control board for plate Input or Output Transport positioner Position control board Motor control board Grab Label decoder board Incubator module
07378 Incubator module
07305
Incubator board
Washer module 0830 1 08300 074 13 07412 05054 08299 07319 08476 Washer module Manifold Aerosol filter Set (10 PCS)filter sheets Dispense pump assy Vacuum pump assy Liquid container unit Connector for liquid container 1 2 2
216
TEKNIKA
CODE :
DESCRIPTION : REC.STOCK :
Dispense module 08298 07436 08651 08297 08296 Reader 07324 07233 07326 07327 07328 07329 07460 07331 Reader module Air filter for lampblock Filter 405nm Filter 450nm Filter 492nm Filter 540nm Filter 620nm Filter 690nm Dispense stationary module Dispense control board Spring pump driver Dispense reagent door Hinge for reagent door
Control system 07266 07228 07234 Tools 07625 07626 08191 08242 08245 08243 08244 08271 08272 08273 08274 08276 08280 Service manual Disinfection aid for MPP 3000 Hoisting bracket set MPP 3000 disinfection set (tubing set for 07626) Field test plate (for Reader) Release hook for Dispense door Adjustment tool for Plate input or output Dummy service plug for Washer Service extension cable for Plate input or output Service extension cable 6 pins for module power Service extension cable 4 pins for module power Service Bitbus extension cable Service 37 pins bus extension cable Bitbus controller board Internal controller board HCT (for Transport, Incubators) Internal controller board (for Washer, Reader, Dispense)
217
TEKNIKA
CODE :
DESCRIPTION REC.STOCK :
Trade-in snare Darts 18340 18341 18343 18344 18345 18346 18347 18348 18349 18350 18351 18352 18353 18354 18355 18356 18357 18358 18361 Label decoder board Position control board Internal controller board (for Washer, Reader, Dispense) Internal controller board HCI (for Transport, Incubators) Grab Reader module Washer module Incubator module Plate Input or Output module Transport positioner Dispense reagent door Dispense stationary module UPS 120v / 60Hz UPS 220V / 50Hz EVGA monitor Computer PC486 Power supply 24V 40A Bitbus controller board Computer 486-66 PackaPing materials (Refer to Technical Note MPP 3OOO.S.04, for detailed information) 07603 Set of main packaging materials for MPP 3000 unit
This set includes following items :
07209 : Top
07212 : Outer sleeve
07215 : Inner sleeve 07240 : Pallet 07256 : Lower buffer (2 pc) 07389 : Side profile (2 pc) 07390 : L-shape profile (2 pc) 07391 : Upper buffer (2 pc) 07172 : Bar (2 PC), 07173 : Eperan buffer A (4 pc) 07174 : Eperan buffer B (4 pc) 07622 Transportation bolt
218
TEKNIKA 08501
CODE :
DESCRIPTION : REC.STOCK : 1
Set of transport protections This set includes following items : 07604 : for Input and Output module 07611 : for Incubator modules 08288 : for Washer module 07615 : for Dispense modules 08216 : Bufferblock grab 08217 : Foamblock transport system 08506 : Protection reader
07355 07356 07357
07359 07360 07361 07362 07363 07364 07365 07367 07368 07369 07370
07373
07374 08477
Inner carton, for article codes : (08304, 18349,07378, 18348,07316) Outer carton, for article codes : (08304, 18349,07378, 18348,07316) Polyether corner, for article codes : (07154, 18357,08304, 18349,07378, 18348,07316,08303,18350, 08302, 18345,08301,18347,07324,18346,08298,18352, 08297, 18351) Inner carton, for article codes : (08301, 18347,07324,18346,08297,18351) Outer carton, for article codes : (08301,18346,07324,18346,08297,18351) Polyether plate, for article codes : (08297, 18351) Inner carton, for article codes : (07154,18357,08298,18352) Outer carton, for article codes : (07154,18357,08298,18352) Carton, for article code : (0715 1) Polyether buffer, for article code : (07151) Outer carton, for article codes : (07189,18354,07203,18353) Esperan corner, for article codes : (07189,18354,07203,18353) Inner carton, for article codes : (08302, 18345) Outer carton, for article codes : (08302, 18345) Outer carton, for article codes : (08303, 18350) Sleeve, for article codes : (08303, 18350) Box, for article codes : (08301, 18347,07324,18346)
DIAGRAMS
219
11. Illustrations
and diwrams
This chapter provides the electronic board schematics and layouts. 11.1. ImDortant
notice :
The schematics and layouts are provided for reference only ! You should not try to perform any repair on the boards. Only those parts mentioned in the spare part list will be provided. Single components for the boards are not available and can not be ordered. Refer to the service philosophy explained in the Introduction chapter of this manual.
DIAGRAMS
-..-_ ^_.
Service
Manual
MPP
3000
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770
DIAGRAMS
221
Fig. 11.1.1. : Layout Internal Controller board HCT
_,_. __ _ -..-.-.-. - --- -_..,_ -__ ---_ --
DIAGRAMS
222
DIAGRAMS
223
Fig. 11.21. : Layout Internal Controller board, stripped version
5----l-
DIAGRAMS
224
~31t:;:::::E::I;:::::5::: a-.... e-..r..*..-----. . . . . . . . . . . . . . . .
i !
DIAGRAMS
22s
Fig. 11.3.1. : Layout Incubator board
ORGANONTEKNIKA f--
r ICI
a-
I____._ . ..^_ .-..-__ ---- ~-_-._ -.-
DIAGRAMS
Fig. 11.3.2. : Diagram and layout Incubator Sensor interconnection board
LC .. 54:. W.,,E f-s:, .
K3
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R2 Rl r-7
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1
II
HI
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I R4-/
I IT7
K3
II
T ac,
I so2
2 b
DIAGRAMS
227
Fig. 11.4. : Diagram and layout Container unit sensor board
NC
ORCANON IEKNIKA
.._.
. --. -~ ------_ -,--.___ ..__ ___I
228
3
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H
L I
l;i
DIAGRAMS
229
Fig. 11.5.1. : Layout Washer control board
ORGANON 1tKNIKA
I:
*a -kY nu
DIAGRAMS
230
.F IL
I i
I I
DIAGRAMS
231
Fig. 11.6.1. : Layout Washer power board
\
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06m
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. . ..~_ .-~-.- -- -..-
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DIAGRAMS
232
I ,
3
r
-, 2: m!
I
DIAGRAMS
233
Fig. 11.7.1. : Layout Dispense control board
>
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X=:=== nnnnnn
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.-... -
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DIAGRAMS
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Go to Table OF Contents .-,_ _. _-
__. ._.._-. _ ._
DIAGRAMS
235
Fig. 11.8.1. : Layout Pump control board
3 9,
I Q \
00 00
OOl
Q, 0,
, Kl Kl KJ
DIAGRAMS
236
Fig. 11.9. : Diagram and layout Transmitter and Receiver board for needle head
I I
: :
1 I
__ I-. . -t-~^ -..---.
DIAGRAMS
237
Fig. 11.10. : Diagram and layout Alert board
6
EVIC
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ORGANON TEKNIKA '

6 RWZ krzl
DIAGRAMS
238
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DIAGRAMS
239
Fig. 11.11.1. : Layout Plate I/O board
a-?%
@. -
J-L -
2 25 Y 1L- :6 G II w/_ I_1 R5L_

rI L a
Cl 5
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I-L -
G -
J 3
t TEKNIKA
13.
DIAGRAMS
L ._
r 1
II
r-
2 E s
r
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DIAGRAMS
241
Fig. 11.12.1. : Layout Position control board
242
Fig. 11.13. Diagram Motor control board
--l
DIAGRAMS
243
Fig. 11.13.1. : Layout Motor control board
d
2.
DIAGRAMS
244
Fig. 11.14. : Diagram and layout Filter board for position control board
POSIT BOARD
POS. INT.
DIAGRAMS
245
Fig. 11.15. : Diagram and layout Position interconnection board for grab CC
r 1
EVIC
DIAGRAMS
246
/; i: .-:
Fig. 11.16. : Diagram and layout Grab sensor board
i:%c PI RI1 LOOK RIO 1.Y f-
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DIAGRAMS
247
DIAGRAMS
248
Fig. 11.17.1. : Layout Grab control board
0 0
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TECHNICAL
NOTES
249
12. Technical Notes

This chapter contains a list of the released Technical Notes related the MPP 3000 system
12.1. TN Index MPP 3000 TN no. : 01 OlA 02 03 04 05 06 07 08 09 09A 10 11 12 13 14 15 16 17 18 19 20 21 22 23 23A Subject : Date : December 1990 September 1991 May 1992 August 1992 February 1993 May 1993 December 1993 November 1993 December 1993 December 1993 January 1994 February 1994 April 1994 July 1994 April 1994 May 1994 April 1994 pending July 1994 May 1994 pending pending cancelled Ref 17 August 1994 August 1994
Installation MPP 3000 Installation MPP 3000 Replacement Reader Software Erratic Microelisatest Results Packing of spare parts Incubator module alignment Use of Blue Carriers Washer Interface Firmware Introduction Hystory Cards MPP SW 1.0, Firmware change MPP SW 1.0, Firmware change Modification Dispense Door Modification Electrical Wiring Modification NCR-PC Motherbrd Introduction new computer Modification Washer Down Sensor Cable I/O Module Mechanical Stop Home Control Delay Action Relay on Monitor Power on Modification Label Decoder PCB Incubator X-drive Error Log Codes Overview Modem Communication Start-up Hints Design Change Grab Sensor Pcb New Transport Firmware and Updating Appl. Software Update, UNIX V3 Appl. Software Update, UNIX V3
REMARK manual.
: The information of these TNs is already integrated in this service
New released technical notes which you may receive should be classified in this chapter to keep this service manual always complete and up to date
TECHNICAL
NOTES
250
FOR YOUR OWN NOTES
I I \
2:
-. _
.. I .l__-..-ll..-l

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Go to Table OF Contents

Service instructions for the Microplate Processor 3000.

Date of printout of this manual: 21 September, 1994

note : Specifications may be modified without prior notification.

of this manual : 21 September, 1994

Return to Opening Page

2.1.1. Central control system 2.1.3. Chemical processing module

overview of the modules

3.2. Detailed description 3.2.1. Power supplies 3.2.1.1. UPS module

~~~~~-----~ 37 procedure ___________-____________________________---------------------requirements 37 37 37 37 41 42 42 51 55 or update 57 59

____--___-__________---------------------------------------93 94 95 96 96 97 97 97 99 103 105 109 113

-^-l ..--. __^

8.1. Cleaning procedure procedure

to Replacement instructions tools

9.1. Recommended 9.2. Panels

195 198 202 202 206

__-____________---__________________ -_______________-________________ 213

in the MPP 3000

in the MPP 3000 unit

in the MPP 3000 unit are listed on

Any service activity performed logging card.

1 - PROCESSOR 2 - MPP-3000-m 3 - MONITOR 4 - KEYBOARD

A short technical description following paragraphs.

3.2.1. Power supplies

computer system.Only the computer systemwith monitor is kept powered during a

(this output is not used in the MPP 3000)

INCUMT'ION STATION I I I HEATING /COOLING CONTROL Y

3.2.3. Washer module

,, ,?r: -,.,:\, ,?; I:

Three wash liquid container Refer to Fig. 3.6.

. Fig. 3.6 : Container module

3.2.5. Dispense module

pump disposablesand needles.

Go to Table OF ..-. Contents . --. -_-.

3.2.6. Reader module

-.. - . ..-.. .-.-----.--

INT. TMNSPORT i IDENTIPICAT. (X11.2.3) I

outputmodule.Also uponrequest, the outputmoduleejectsthis stackof plate

SYSTEM MPP 3000 OPERATING ENVIRONMENT

To maintain setviceability, minimum of unobstructed requirements: A properly grounded outlet

(15 A at 12OV) to the MPP 3000. instrument. as a

(4 feet) of the installed

using the same type of phone

lines as that are used for a FAX-machine

at the time of order

CUSTOMER SURVEY FOR SYSTEM MPP 3000~ SYSTEM DELIVERY/INSTALLATION REQUIREMENTS

dock and the location

must take into account

dock and the

CHECKLIST FOR OT-REPRESENTATIVE PRE-INSTALLATION SITE INSPECTION

FOR A OF MPP 3000

SATISFACTORY ACITON REQUIRED SATISFACTORY ACTION ACTION REQUIRED REOUIRED

Temperature Comments: Room relative

range : 15C to 25C

lights. The instrument

path of air draft.

3.50 kg (772 Ibs).

side of the table.

Comments: [] [J SATISFACTORY ACTION REQUIRED Electrical

1. A properly 120V) Comments:

to the MPP 3000.

2. The AC power Comments: 3. To ensure devices

must be within of the MPP Power

~~~~~-----~ 37 procedure _-__________________---------------------requirements 37 37 37 37 41 42 42 51 55 or update 57 59

__--_-__________---------------------------------------93 94 95 96 96 97 97 97 99 103 105 109 113

---- -_-__________ 213