Afghanistan was not always religiously homogeneous, and Zoroastrians, Buddhists, Jews, and Greeks all left an imprint

on its early history. Following Alexander the Great's brief occupation in the 4th century BCE, the successor-state Seleucid Empire controlled the area until 305 BCE when they gave much of it to the Indian Maurya Empire as part of an alliance treaty. The Mauryans brought Buddhism from India and controlled southern Afghanistan until about 185 BCE when they were overthrown.

In the 7th century, the Umayyad Arab Muslims entered into the area now known as Afghanistan after decisively defeating the Sassanians in the Battle of Nihawand (642 CE). Following this colossal defeat, the last Sassanid Emperor, Yazdegerd III, became a hunted fugitive and fled eastward deep into Central Asia. In pursuing Yazdegerd, the Arabs chose to enter the area from north-eastern Iran[7] and thereafter into Herat, where they stationed a large portion of their army before advancing toward the rest of Afghanistan. The Arabs exerted considerable efforts toward propagating Islam amongst the locals.

A large number of the inhabitants of the region of northern Afghanistan accepted Islam through Umayyad missionary efforts, particularly under the reigns of Hisham ibn Abd al-Malik (caliph from 723 to 733) and Umar ibn AbdulAziz (caliph from 717 to 720).[8] During the reign of Al-Mu'tasim Islam was generally practiced amongst most inhabitants of the region and finally under Ya'qub-i Laith Saffari, Islam was by far, the predominant religion of Kabul along with other major cities of Afghanistan. Later, the Samanids propagated Islam deep into the heart of Central Asia, as the first complete translation of the Qur'an into Persian occurred in the 9th century. Since the 9th century, Islam has dominated the country's religious landscape. Islamic leaders have entered the political sphere at various times of crisis, but rarely exercised secular authority for long. The remnants of a Shahi presence in Afghanistan's eastern borders were expelled by Mahmud of Ghazni during 998 and 1030.[9] The 1979 Soviet invasion in support of a communist government triggered a major intervention of religion into Afghan political conflict, and Islam united the multiethnic political opposition. Once the Soviet-backed Marxist-style regime came to power in Afghanistan, the People's Democratic Party of Afghanistan (PDPA) moved to suppress religion. The "atheistic" and "infidel" communist PDPA imprisoned, tortured and murdered many members of the religious establishment.[11][12] After National Reconciliation talks in 1987 Islam became once again the state religion and the country removed the word "Democratic" from its official name. From 1987-1992 the country's official name was the Republic of Afghanistan[13] but today it is an Islamic Republic. For Afghans, Islam represents a potentially unifying symbolic system which offsets the divisiveness that frequently rises from the existence of a deep pride in tribal loyalties and an abounding sense of personal and family honor found in multitribal and multiethnic societies such as Afghanistan. Mosques serve not only as places of worship, but for a multitude of functions, including shelter for guests, places to meet and converse, the focus of social religious festivities and schools. Almost every Afghan has at one time during his youth studied at a mosque school; for some this is the only formal education they receive.