GUVIClean

Prospectus
Oct.2013

HAI:TheProblem
HealthcareAssociatedInfectionsareaseriousproblem:
Affect~1in20patients1 Resultin$28B$45Bperyearinadditionalhealthcareexpenditures2,4 In2002theestimatednumberofHAIsinU.S.hospitalswasestimatedtobe1.7M withnearly100,000oftheseHAIsresultingindeath.3 AveragecostperHAI~$20,000$26,000.4 HAIhasbecomesuchasignificantexpensethatsection5001(c)oftheDeficit ReductionActstatesthathospitalswillnolongerreceivereimbursementfromCMS forselectedconditionsrelatedtoHAI,addingsignificanteconomicburdento numerousU.S.hospitals. HAIscausedbyinfectiousagents:bacteria,fungi,virusesorotherpathogens HAIsareassociatedwithavarietyofriskfactors,including:

1. 2. 3. 4.

Indwellingmedicaldevicessuchasbloodstream,endotracheal,andurinarycatheters Surgicalprocedures Injections Contaminationofthehealthcareenvironment Transmissionofcommunicablediseasesbetweenpatientsandhealthcareworkers Overuseorimproperuseofantibiotics

http://www.hhs.gov/ash/initiatives/hai/index.html Hospitalacquiredinfectionsonly:http://www.hhs.gov/ash/initiatives/hai/exec_summary.html Klevins,etal.EstimatingHealthCareAssociatedInfectionsandDeathsinU.S.Hospitals,2002 Scott,TheDirectMedicalCostsofHealthcareAssociatedInfectionsinU.S.HospitalsandtheBenefitsofPrevention,March2009

HAIInPrimaryCare
PrimaryCareProvidershavespecialchallenges Firstlineofcare:Dontalwaysknowwhattheyaregettingintountildiagnosis iscomplete Facilitiesaretypicallylimited Challengeswithpointofcaresterilizationofcommonlyusedinstruments BPCuffs,Stethoscopes,Otoscopes,PatellaHammers,TuningForks, Trays,Bottles,Ophthamoloscopes,Endoscopes,Proctoscopes, ExaminationLights,Thermometers,MeasuringTapes,andthelike Sendinginstruments/equipmentouttobesterilizedisexpensiveand inconvenientandrequiresmultipleredundanciesof instruments/equipment Pointofusesterilizationishighlypreferred,buttheequipment(typically autoclave)isexpensiveandtimeconsumingandmaydamagecertain instruments. Aninexpensive,effective,simpleandfastmethodofpointofuse disinfection/sterilizationisneededforPrimaryCareapplications.

TheSolution:GUVIClean
GUVICleanisasimple,pointofusecabinetusedto disinfecttypicalprimarycareinstrumentsatpointofuse. Itissimple,quickandeffectiveaswellasinexpensive GUVICleanutilizesGermicidalUVIllumination, combinedwithspecializedfixturing andreflectordesign andmaterialstomoreeffectivelydisinfect/sterilize commonuseinstruments Additionaltreatments(ebeam,sanitizinggases,etc.) mayalsobeusedinGUVICleantoensuresanitary instrumentsinatimelymanner) GUVICleanusesinterlocksandsmartsensorstoensure safetyoftheuser,enablingpointofuse disinfection/sterilizationintheexaminationroom.

GUVICleanthebettersolution
PatentPendingGUVI chamber Utilizingmaterialsand designsthatarehighly reflectiveofUVCforfull internalreflectionofGUVI Utilizesfixturing materials anddesignsthatarehighly transmissive ofUVCforfull exposureofallareastreated FullGUVIexposuretoenable disinfection/sanitizationina simple,safe,lowcostpoint ofusecabinet

GUVIClean

AccessoriesforGUVISterilizers
PatentPendingBPCuff withextensionstringsfor hanginginGUVIChamber withoutobstructionof GUVItoCuff PatentPendingQuartz ClipandOtherUVC transparentfixturing for unobstructedexposureof itemstobe disinfected/sterilizedto GUVI FullGUVIexposureto enableeasyandfull disinfection/sterilization inasimpledesign.

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GUVICuff

QuartzClip

MarketPotential:US
PrimaryCare: 209,000PracticingPCPs:1 62KUnitsAnnually Dentist 195,941PracticingDentists:2 58KUnitsAnnually Totalest.USTAM(EAU):120KUnits,$90MUS Annually(assumes$750USEachperGUVIClean) Other(SpecializedCare,NonPCPClinics,Therapy,etc.) notincluded
1. 2. http://www.ahrq.gov/research/findings/factsheets/primary/pcwork1/index.html...Assumes3examinationroomsperPCP,oneGUVICleanper examinationroomand10yeartransitiontoGUVIClean http://kff.org/other/stateindicator/totaldentists/ Assumes3workroomsperDentist,oneGUVICleanperroomand10yeartransitiontoGUVIClean

Approach
LicenseAvailablefromUSCIPTechTransferOffice (SCRF#01044)tosuitableentrepreneurial designer/manufacturer Keystosuccess: Effective,lowcostdesignandmaterials selection Proofofefficacy FindinganexcellentMFG/Selling/Distribution Partner

GUVICleanthebettersolution
Pointofusesimplicity Lowcostperformance FastandEffective Disinfection/Sterilization SafeandEffectiveDesign LessRedundantInstrument InventoryRequired LineofTransmissive Fixturing

GUVIClean