Generic Name and Brand Name

Classifi -cation

Action

Dosage

Indication

Contraindication Contraindications

Side Effects

Nursing Responsibi-lity Nursing Responsibi-lities

Methylergonovin Oxytoe maleate cic Drug Methergine

Synthetic drug related to ergonovine. Acts directly on the uterine smooth muscle to stimulate the rate, tone, and amplitude of uterine contraction s. It induces a rapid, sustained tetanic uterotonic effect that shortens the third stage of labor and reduces blood loss. The uterus

Indications IM; IV (Emergencie 1. Prevention s Only) and managemen 0.2 mg q 2 t of 4 hr postpartum following and delivery of postabortal placenta, of hemorrhage the anterior by producing shoulder, or firm uterine during the contractions puerperium. and decreasing Tablets uterine bleeding. 0.2 mg 34 2. During the times per second stage day in the of labor puerperium following for a delivery of maximum of the anterior 1 week. shoulder, but only under full obstetric

Side Effects

Hypertension Pregnancy, associated BEFORE: toxemia, with seizure Take hypertension. or headache. Ergot palpitation, blood hypersensitivit transient pressure y. To induce chest pains., before labor or diarrhea, foul administ taste. threatened ering. spontaneous Notify CNS: abortions. physician Dizziness, Administration if there is before delivery headache, high of the blood . placenta. Use pressure. with CYP3A4 Miscellaneou Assess inhibitors (e.g., s: Sweating, for dyspnea, protease fundal hematuria, inhibitors, tone, water macrolide massage intoxication, antibiotics, the leg cramps, azole fundus nasal antifungal and congestion. drugs). check for relaxatio n.

becomes more sensitive to the drug toward the end of pregnancy.

supervision.

Give only if solution is colorless. Discard if it is cloudy.