[ M.Sc.

(CHEMISTRY) PART-I (SEMESTER I & II) ]

SYLLABUS M.Sc. (CHEMISTRY) Part-I (SEMESTER I & II)

(2012-2013) Paper Code Title of Paper No. of Lectures SEMESTER-I MCH 101 MCH 102 MCH 103 *MCH 104 (A) *MCH 104 (B) PRACTICALS MCH 105 MCH 106 SEMINAR I SEMESTER-II MCH 201 MCH 202 MCH 203 MCH 204 PRACTICALS MCH 205 MCH 206 Inorganic Chemistry Organic Chemistry Physical Chemistry Mathematics for Chemists OR Biology for Chemists Inorganic Chemistry Practical Analytical Chemistry Practical 65 65 65 65 65 100 100 70 70 70 70 70 100 100
20

Max. Time Mark s Allowed

3 hrs. 3 hrs. 3 hrs. 3 hrs. 3 hrs. 6 hrs. 6 hrs. hrs.

Inorganic Chemistry Organic Chemistry Physical Chemistry Computer Fundamentals and Programming with C Organic Chemistry Physical Chemistry

65 65 65 65

70 70 70 70

3 hrs. 3 hrs. 3 hrs. 3 hrs.

100 100

100 100
20

6 hrs. 6 hrs. hrs.

SEMINAR II INDUSTRIAL TRAINING:

The candidates will be required to undergo training in a specific industry / R & D Organizations and will have to submit project report followed by its presentation and viva voce. Candidates will be awarded grade for the project report. * Note: B.Sc. Non-medical students will take Biology for Chemists paper while B.Sc. Medical students will take the paper Mathematics for Chemists

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

SEMESTER-I PAPER-MCH 101: INORGANIC CHEMISTRY

Maximum Marks: 70 (i) Semester Examination: 60 (ii) Internal Assessment: 10 Lectures:65 Time: 3 hours Pass marks: 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections: A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions (two from each section) and will be of 1 marks each.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one question from each section: A, B, C and D. Section E is compulsory.

SECTION-A

17 Hrs.

Group Theory : The concept of group, order and classes of group, symmetry elements, symmetry operations and their matrix representation, multiplication tables, point group determination, determination of reducible and irreducible representations, character tables, construction of character tables for C2V and C3V point groups, application of group theory to chemical bonding, use of character tables to determine which metal orbitals are used in and bond formation in Oh, Td and square planar complexes, splitting of d-orbitals under the influence of octahedral, tetrahedral, square planar and trigonal bipyramidal symmetry, the directed valence for Oh and Td symmetry

SECTION-B

16 Hrs.

Applications of Group Theory in Spectroscopy : Symmetry considerations regarding selection rules and spectral intensities, vibronic coupling, vibronic polarization in centrosymmetric complexes and non-centrosymmetric complexes, polarization of electronically allowed transitions, selection rules regarding IR and Raman scattering spectroscopy, fundamentals, overtones and combinations in vibrational spectroscopy, mutual exclusion principle, symmetry symbols for normal modes of vibration, IR and Raman activity of their fundamentals and nature of vibrations in terms of change in internal coordinates in simple molecules like trans N2,F2, SF6

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] SECTION-C 16 Hrs.

Nuclear Chemistry : Nuclear structure, nuclear particles, nuclear forces, packing fraction, mass defect, binding energy, stability of nucleus, magic numbers, nuclear models, radioactivity, equations of radioactive decay and growth, half life and average life, radioactive equilibrium: transient and secular. Nuclear reactions: energetics of nuclear reactions, Q-value of reaction, types of nuclear reactions, nuclear fission and fusion, neutron capture cross section and critical size, principles of working of reactors of nuclear power plants, breeder reactor, detection and measurement of radiation, principles of working of different counters: Geiger Muller, Proportional and Ionisation counters, applications of radioactivity: tracer techniques, neutron activation analysis.

SECTION-D

16 Hrs.

Bioinorganic : Essential and trace elements, importance of metal ions in biological system, Na+/K+ pump, biochemistry of iron, Iron storage and transport pigments, metalloporphyrins, chlorophyll and photosynthetic reaction centre, transport and storage of O2, haemoglobin and myoglobin, mechanism of O2 binding and transport, cooperativity in Hb, Bohr effect, other O2 carrying pigments, hemerythrin and hemocyanin, cytochromes, catalases, peroxidases, iron sulphur proteins. Metalloenzymes: Zn enzymes carboxypeptidase and carbonic anhydrase, Cu enzyme superoxide dismutase, Xanthine oxidase, aldehyde oxidase, nitrogen fixation and nitrogenases, metal deficiency diseases, toxic effects of metals, metal complexes as antitumour agents, chelation therapy, antiarthritis drugs, lithium and mental health

References: 1. Chemical Applications of group theory- F.A. Cotton 2. Symmetry in Chemistry- Jaffe and Orchin 3. Inorganic Chemistry- Meissler and Tarr 4. Bioinorganic- Bertini, Gray, Lippard and Valentine 5. Introduction to Radiochemistry- Fiedlander and Kennady 6. Nuclear and Radiochemistry-Fiedlander, Kennady and Mites 7. Essentials of nuclear Chemistry-H.J. Arnikar

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPER MCH 102: ORGANIC CHEMISTRY

Maximum Marks: 70 (i) Semester Examination: 60 (ii) Internal Assessment: 10 Lectures: 65 Time: 3 hours Pass marks: 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections: A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions (two from each section) and will be of 1 marks each.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one question from each section: A, B, C and D. Section E is compulsory.

SECTION -A
Aromaticity: Introduction to fullerenes, Aromaticity in benzenoid and non-benzenoid compounds, Alternant and non-alternant hydrocarbons, Huckels rule, Anti-aromaticity, Homoaromaticity, Annulenes. Reactive Intermediates: (i) Carbocations : Generation, Structure, Stability, allylic and benzyllic carbocations. Stereochemistry and reactions. Nonclassical carbocations : Phenonium ion, norbornyl system, (ii) Carbanions : Generation, Structure, stability, stereochemistry and general reactions. (iii) Carbenes : Formation, Structure, Singlet & Triplet carbene, Stereochemsitry and reactions. (iv) Nitrenes : Formation, Structure Singlet & Triplet nitrene, Stereochemsitry and reactions. (v) Arynes : Formation, Structure and reactions. (vi) Free radicals : Formation, Structure, Stability, Stereo-chemsitry and reactions. SECTION-B Elimination Reactions: E2, E1 and E1cB mechanism, stereochemistry, product ratio, orientation of double bond, Hoffmans rule, Saytzeff s rule, Factors governing E2 and E1 mechanism. Mechanism and orientation in pyrolytic elimination reactions.
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16 Hrs.

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] Cyclic Elimination: Amine Oxide, Esters,Xanthate, Free redical elimination. Elimination versus substitution. Effect of solvent, Temperature, Nature of Base, Structure of Reactant. Aromatic Elimination: Benzyne, Nucleophilic aromatic substitution, addition elimination.

SECTION-C Pericyclic Reactions:

16 Hrs.

Molecular orbital symmetry, Frontier orbitals of ethylene; 1,3-butadiene; 1,3,5hexatriene and allyl system. Classification of pericyclic reactions. WoodwardHoffmann correlation diagrams. FMO & PMO approach. Electrocyclic reactions: Conrotatory and disrotatory motions, 4n, 4n+2, and allyl systems. Cycloadditions: antarafacial and suprafacial additions, 4n, 4n+2 systems, 2+2 addition of ketenes; 1,3dipolar cycloadditions and chelotropic reactions. Sigmatropic rearrangements: suprafacial and antarafacial shift of hydrogen, Sigmatropic shifts involving carbon moieties. Claisen, Cope and Aza-Cope rearrangements, Ene reactions. SECTION-D Stereochemistry: Stereoisomerism: Introduction and different types of stereoisomerisom. Fisher, Newman and Saw horse representations for organic compounds. Elements of Symmetry, Chirality, Molecules with more than one chiral centre. Threo and Erythro isomers. Stereochemical nomenclature. Prochirality-Enatiotopic and distereotopic atoms, groups and faces. Stereospecific and stereoselective synthesis. Optical activity in the absence of chiral carbon ( biphenyls, alkenes and spiranes). Chirality due to helical shape. 17 Hrs.

References: 1. Advanced Organic Chemistry-Reactions, Mechanism and structure, Jerry March, John Wiley. 2. Advanced Organic Chemistry, F.A. Carey & R.J. Sundberg, Plenum. 3. A guide book to Mechanism in Organic Chemistry, Peter Sykes, Longman. 4. Structure and mechanism in Organic Chemistry, C.K. Ingold, Cornell University Press. 5. Organic Chemistry, R.T. Morrison and R.N. Boyd, Printice Hall. 6. Modern Organic Reactions, H.O. House, Benjamin. 7. Reaction Mechanism in Organic Chemistry, S.M. Mukherji & S.P. Singh. Macmillan. 8. Highlights of organic Chemistry, W.J.L. Nobel, An Advanced Text Book.
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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPER MCH 103 : PHYSICAL CHEMISTRY

Maximum Marks: 70 (i) Semester Examination: 60 (ii) Internal Assessment: 10 Lectures: 65 Time: 3 hours Pass marks: 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections: A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions ( two from each section ) and will be of 1 marks each.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one question from each section : A, B, C and D. Section E is compulsory.

SECTION-A

16 Hrs.

Basic of chemical Thermodynamics : Thermodynamic Properties:- state and path properties.First and second law of thermodynamics. Maxwell relations. Thermodynamic equation of state. Joule Thomson effect . Nearnst heat theorem . Themodynamic entropy. Evaluation of absolute entropy . Third law thermodynamics ,Indentificatoin of statistical and thermodynamic entropy,Determination of Absolute Entropies of Solids,Liquids and Gases. Non ideal systems: - Excess thermodynamic functions . Determinations of partial molar properties . Fugacity and activity . Fugacity of gases . Fugacity of mixture of gases. Concept of fugacity and its experimental determination . Determination of activity and activity coefficients of non electrolytes ,partial molal properties and their determination. Themodynamics and living systems: Simultaneous or coupled reactions . Coupled reactions and metabolism. Free energy utilisation in metabolism . Terminal oxidation chain . Overall metabolic plan . General thermodynamic consideration of living systems .

SECTION-B

16 Hrs.

Statistical Thermodynamics : Concept of distribution. Thermodynamic probability and most probable distribution. Canonical and other ensembles. Statistical mechanics for systems of independent particles and its importance in chemistry. Types of statistics, Maxwell-Boltzmann, Bose-Einstein and Fermi-Dirac statistics. Idea of microstates and macrostates . Thermodynamics probability for the three types of statistics. Derivation of distribution laws(most probable distribution) for the three types of statistics . Lagranges undermined multipliers .Stirlings approximation
6

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] .Molecular partition function and its importance. Translational, Rotational ,Vibrational ,electronic and nuclear partition functions . Expression for internal energy ,entropy, Helmhotz function ,Gibbs function, pressure, work and heat in terms of partition function.

SECTION-C
Electrochemistry

17 Hrs.

Ionics:-Ions in solution , Deviation from ideal behaviour .Ionic activity, Born equation , ion-ion interaction ,Debye Huckel theory of activity coefficients of strong electrolytes , Equation for appreciable concentration . Activity coefficient and its determination .Activities in concentrated solutions . Debye-Huckel limiting law ,Verification of Debye-Huckel limiting law. Bjerrums theory of ion association in electrolyte solutions ,Mean activity coefficients and their experimental determination. Activity coefficients as a function of ion-ion and ion-solvent interactions.Some applications of Conductance Measurements Conductance and Ionic Mobilities :- Ion association. Ion transport. Debye-Huckel ,Onsager equation. Conductance of high frequencies and high potentials. Variation of equivalent conductance with concentration. Modification of Debye-Huckel Onsager equation. Ion pair formation. Ion triplets in electrolyte solutions. Ion triplets and conductance. Ionic conductances and ion- pair formation

SECTION-D

16 Hrs.

Electrocatalysis:- A chemical catalyst and an electrochemical catalyst, Electrocatalysis in redox reactions, Electrocatalysis in reaction involving adsorbed species. Some specific features of electrocatalysis Kinetics of electrode reactions:-The Buttler Volmer equation, the diffusion over potential Bioelectrochemistry:-Cells membranes, membrane potentials and their theories The Hodgkin-Huxley theory of membrane potentials, References: 1. Bockris and Reddy, Modern Electrochemistry ,vol I & II. 2. Glasstone Electrochemistry. 3. Dickerson,Molecular Thermodynamics . 4. Glasstone Thermodynamics for chemists.

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPERMCH 104(A) : MATHEMATICS FOR CHEMISTS (For Students without Mathematics in B.Sc.)
Maximum Marks : 70 (i) University Examination : 60 (ii) Internal Assessment : 10 Lectures : 65 Time : 3 Hours Pass Marks : 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections : A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions (two from each section) and will be of 1 marks each.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one questions from each section : A, B, C and D. Section E is compulsory

SECTION-A
th

16 Hrs.

Matric Algebra : Addition and multiplication, determinants (up to 4 order) inverse, adjoint and transpose of matrices ,special matrices(Symmetric, skew symmetric, hermitian, skew-hermitian, unit ,diagonal ,unitary etc.) and their properties.Matrix equations:Homogeneous,non homogeneous, linear equations and conditions for the solutions,linear dependence and independence .Cayley Hamiltion theorem ,matrix eigenvalues and eigen vectors.

SECTIONS-B

16Hrs.

Coordinate Geometry : Cartesian system of co-ordinates in the plane, slope of a line ,parallel and perpendicular lines, intercepts of a line on the co-ordinate axes .Various forms of equations of a line- parallel to axis slope intercept form ,the point slope form two point form ,intercept form ,normal form and general forms. Trigonmetry : Degree and radian measure of positive and negative angles,relation between degree and radian ,definition of trigonometric functions with the help of unit circle ,Periodic functions ,Cencept of periodicity of trigonometric functions ,values of trigonmertric functions for different angles, trigonometric functions of sum and differences of angles ,additions and subtraction formulae .

SECTION-C

16Hrs.

Calculus : Differential calculus :Functions, continuity and differentiability, rules for differentiation,applications of differential calculus including maxima and minima. Functions of several variables, partial differentiation, Euler theorem co-ordinate transformations(e.g. cartesian to spherical polar)
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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] Intergral calculus : Basic rules for integration,integration by parts partial fraction and substitiution,definite integrals .

SECTION-D
Elementary Differential Equations:

16 Hrs.

Variables separable and exact , first order differential equations .Homogeneous exact and linear equations.Applications to chemical kinetics, secular equilibria,quantum chemistryetc. Permutation and probability Permutations and combinations, probality probability theorems,probality curves, average ,root mean square and most probable errors ,examples from the kinetic theory of gases.

References: 1. The chemistry Mathematics Book ,E. Steiner,Oxford University Press 2. Mathematics for chemistry,Doggett and sucliffe. 3. Mathematical preparationsfor physical chemistry,F. Daniels,McGraw Hill

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPERMCH 104(B) : BIOLOGY FOR CHEMISTS

Maximum Marks : 70 (i) University Examination : 60 (ii) Internal Assessment : 10 Lectures : 65 Time : 3 Hours Pass Marks : 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections : A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions (two from each section) and will be of 1 marks each.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one questions from each section : A, B, C and D. Section E is compulsory

SECTION-A

16 Hrs.

Origin of Life : Unique properties of Carbon, Chemical evolution and rise of living systems. Introudction of biomolecules, building blocks of biomolecules. Cell Structure & Functions : Structure of prokaryotic .& eukaryotic cells, Intrcellular organelles and their functions, Comparison of plant and animal cells. Overview of metaboli c process - catabolism and Anabolism. ATP - the Biological energy currency. Cell Division : Cell division stages of mitosis & meiosis. Significance of cell division and fertilization.

SECTION-B

17 Hrs.

Carbohydrates : Conformation of monosaccharides, structure & functions of important derivatives of monosaccharides like glycosides, deoxy sugars, myoinositol, amino sugars, N-acetyl muramic acid, Sialic acid, disaccharide & Polysaccharides. Structural polysaccharides - cellulose and chitin. Storage Polysaccharides - starch and glycogen. Structure and Biological functions of glucosamino glycans or muco polysaccharides, Carbohydrates of glycoproteins and glycolipids. Role of sugars in Biological recognition. Blood group substances, Ascorbic acid. Carbohydrate metabolism Kreb's Cycle, glycolysis, glycogenesis and glycogenolysis, gluconeogenesis, Pentose phosphate Pathway.

10

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] Lipids : Fatty acids, essential fatty acids, structure and function of triglycerols glycerophospholipids, Sphingolipids, cholesterol, Bile acids, prostaglandins, Lipoproteins composition and function role in atherosclerosis, Properties of lipid aggregates micelles, bilayers, liposomes and their possible biological f unctions, Biological membranes. Fluid mosaic model of membrane structure. Lipid metabolism - oxidation of fatty acids.

SECTION-C

16 Hrs.

Structure of Proteins : Chemical and enzymatic hydrolysis of Proteins to peptides, amino acid. Secondary structure of proteins, forces responsible for holiding of secondary structure, -triple helix, -sheets, super secondary structure, triple helix structure of collagen/Tertiary structure of protein folding and domain structure. Quarternary structure. Amino acid metabolism : Degradation and biosynthesis of amino acids ( An overview), sequence determination : Edman degradation. Chemistry of oxytocin and thyroxine releasing hormone (TRH). Enzymes : Enzymes as biological catalyst and mode of their action.

SECTION-D

16 Hrs.

Structure of Nucleic Acids : Purines and Pyrimidine bases of nucleic acids, base pairing via H-bonding. Structure of ribonucleic acids (RNA) and deoxyribonucleic acids (DNA), double helix model of DNA and forces responsible for holding' it Chemical and enzymatic hydrolysis of Nucleic acids. Replication of DNA: The chemical basis of heredity and overview of replication of DNA. Protein synthesis & Genetic Code: Transcription, translation and genetic code. References: 1. Principles of Biochemistry, A.L. Lehninger, Worth Publishers. 2. Biochemistry, L. Stryer, W.H. Freeman. 3. Biochemistry, J. David Rawn, Neil Patterson. 4. Biochemistry, Voet and Voet, John Wiley. 5. Outlines of Biochemistry, E.E. Conn and P.K. Stumpf, John Wiley.

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPER MCH 105 : INORGANIC CHEMISTRY PRACTICALS

Maximum Marks : 100 (i) Semester Paper : 80 (ii) Internal Assessment : 20 Time : 6 Hours

1. Oxidation Reduction titration: a) Standardisation of KMnO4 and determination of nitrites. b) Standardization of K2Cr2O7 and determination of Fe2+ c) Standardisation of Ce (IV) sulphate and determination of Cu2+ d) Standardisation of Na2S2O3 with KIO3 and determination of Ie) Determination of available Chlorine in bleaching powder. 2. Precipitation Titration: a) Standardisation of AgNO3 by using adsorption indicator. b) Standardisation of thiocyanate solution and determination of Chloride by Volhard Method. 3. Complexometric Titrations: a) Determination of Ca2+ by substitution titration. b) Determination of Al3+ by back titration. c) Determination of Cu2+ and Ni2+ by using masking reagents. d) Determination of total hardness of water by EDTA titration 4. Gravimetric/titrimetric determination of mixed ions: a) Copper-Nickel b) Iron-nickel c) Iron-cobalt d) Copper-Zinc Preparation of following compounds: 1. 2. 3. 4. Preparation of Tetraammine copper(II) sulphate Preparation of Hexammine-cobalt (III) chloride. Preparation of Chloropentamminecobalt(III) chloride Preparation of Tris-thioureacuprous chloride

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPERMCH106:ANALYTICALCHEMISTRY PRACTICAL
Maximum Marks : 100 (i) Semester Paper : 80 (ii) Internal Assessment : 20

Time : 6 Hours

1. To determine the percentage purity of given sample of ZnSO4.7H2O by complexometric titration. 2. To determine the percentage purity of given sample of NiSO4.7H2O by complexometric titration using Erichrome black T. 3. To determine composition of Ca and Mg in the mixture of the given solution. 4. To determine the percentage purity of given sample of KBr using adsorption indicator(Eosin). 5. To determine the strength of ascorbic acid in the given solution of vitamin C tablet by titrating against (a) standard I2 solution (b) standard sodium thiosulphate solution. 6. To determine the amount of H2O2 in the given solution by titrating against (a) standard KMnO4 solution (b) standard sodium thiosulphate solution. 7. To determine the percentage purity of given sample of KI by titrating against standard KIO3 solution. 8. To determine the strength of HCl and CH3COOH solution by titrating it against NaOH pH metrically. 9. To determine the composition of HCl and CH3COOH solution by titrating it against NaOH pH meterically. 10. To determine the strength of HCl and CH3COOH solution by titrating it against NaOH cunductometerically. 11. To determine the strength and composition of HCl and CH3COOH solution by titrating it against NaOH conductometerically. 12. To determine the strength of FeSO4.7H2O solution by titrating it against standard KMnO4 solution potentiometerically. 13. To determine the strength of CuSO4.5H2O solution colorimetrically. 14. To determine the strength of K2Cr2O7 solution colorimetrically

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

SEMINAR
Maximum Marks : 20 Time : Hr.

Every candidate will have to deliver a seminar of 30 minutes duration on a topic which will be chosen by him/her in consultation with the teacher of the department. The seminar will be delivered before the students and teachers of the department. A three member committee (one coordinator and two teachers of the department of different branches) duly approved by the departmental council will be constituted to evaluate the seminar. The following factors will be taken into consideration while evaluating the candidate. 1. Expression 2. Presentation 3. Depth of the subject matter and answers to the questions.

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

SEMESTER-II PAPER- MCH 201: INORGANIC CHEMISTRY

Maximum Marks: 70 (i) Semester Examination: 60 (ii) Internal Assessment: 10 Lectures: 65 Time: 3 hours Pass marks: 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections: A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions (two from each section ) and will be of 1 marks each. INSTRUCTIONS FOR THE CANDIDATES Candidates are required to attempt one question from each section: A, B, C and D. Section E is compulsory.

SECTION-A
Theories of metal ligand bonding

16 Hrs.

Valence bond theory and its limitations, crystal field theory: splitting of d-orbitals in different environments, factors affecting magnitude of crystal field splitting, CFSE and its calculation, structural (ionic radii, Jahn-Teller effects) and thermodynamic effects (hydration and lattice energy) of crystal field splitting, crystal field splitting and magnetic properties of transition metal complexes, ligand field theory: evidences of metal ligand overlap in complexes, molecular orbital theory of coordination complexes: molecular orbital energy level diagrams for octahedral, tetrahedral and square planar complexes showing and bonding in transition metal complexes

SECTION-B

17 Hrs.

Atomic Spectroscopy : Spin and orbital angular momenta, LS and j-j coupling schemes, determination of free ion terms for pn and dn configurations, calculation of number of microstates, determination of ground state terms-Hunds rule, hole formulism, spin-orbit coupling , splitting of S,P,D,F,G,H,I terms under the effect of weak octahedral and tetrahedral fields Free ions in medium and strong crystal fields : Strong field configurations, transitions from weak to strong crystal fields, construction of correlation diagrams, spin cross over in coordination compounds, Orgel diagrams, Tanabe sugano diagrams.

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

SECTION-C

16 Hrs.

Spectral properties of transition metal complexes : Selection rules for electronic transitions, relaxation of selection rules, factors influencing band widths, band shapes and intensities, discussion of electronic spectra of octahedral and tetrahedral d1-d 9 metal ions, calculation of 10 Dq and B with use of Orgel and Tanabe Sugano diagrams, electronic absorption spectra of spin paired complexes, spectrochemical series, comparison of d-d bands with f-f bands, charge transfer spectra,

SECTION-D

16 Hrs.

Magnetic properties of transition metal complexes : Origin of magnetic behaviour, types of magnetic behaviour: diamagnetism, paramagnetism. Types of paramagnetic behaviour: large multiplet separation, small multiplet separation. Ferromagnetism and antiferromagnetism, spin only magnetic moment values, quenching of orbital angular momentum, orbital contribution to magnetic moment, magnetic susceptibility, measurement of magnetic susceptibility by Gouy method, Van Vleck formula for magnetic susceptibility, temperature dependence of magnetic susceptibility. References: 1. Advanced Inorganic Chemistry-Cotton and Wilkinson 2. Theoretical Inorganic Chemistry- Day and Selbin 3. Concise Inorganic Chemistry-J.D. Lee 4. Introduction to Ligand Fields-B.N. Figgis 5. Physical Methods in Inorganic Chemistry-R.S. Drago 6. Introduction to Magnetochemistry-A. Earnshaw

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPER MCH 202 : ORGANIC CHEMISTRY

Maximum Marks : 70 (i) Semester Paper : 60 (ii) Internal Assessment : 10 Lectures : 65 Time : 3 Hours Pass Marks: 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections: A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions ( two from each section ) and will be of 1 marks each.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one question from each section : A, B, C and D. Section E is compulsory.

SECTION-A
Stereochemistry:

16 Hrs.

Methods of resolution of acids, bases, amino acids, alcohols, aldehydes, ketones. Asymmetric synthesis: principle and categories with specific examples of asymmetric synthesis including newer methods involving enzymatic and catalytic reactions. Enantio and diastereoselective synthesis. Methods of determining the configuration. Cram's Rule and Prelog's Rule. Conformational of cyclohexane, Equatorial and axial bonds in chair form of cyclohexane, Monosubstituted cyclohexanes, Conformational analysis of Mono and Disubstituted cyclohexanes Relative stability of conformers.

SECTION-B

16 Hrs.

Stereoisomerism of Disubstituted cyclohexanes ( cis and trans isomers and chirality ), Equilibria of Disubstituted cyclohexanes and related systems. Effect of conformation on reactivity cyclic system Introduction, Conformation of sugars anomeric effect, polycyclic compounds, cyclohexene and cyclohexanones. Geometrical Isomerism : Nomenclature (E & Z) Nature of geometrical isomerism and determination of Configuration Curtin Hammet Principle Study of Physical properties of the isomers, Relative stability and interconversion of Geometrical isomers.

SECTION-C

16 Hrs.

Addition to Carbon Carbon Multiple Bond:Mechanistic and sterochemical aspects of addition reactions involving electrophiles, nucleophiles and free radicals.
17

[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] Regioselectivity and Chemoselectivity. Orientations and reactivity. Addition to cyclopropane ring. Hydrogenation of double bond and triple bond and aromatic rings. Hydroboration, Michael reaction, sharpless asymmetric Epoxidation. Addition to Carbon Hetero Multiple bond: Mechanism of Metal hydrides. Reduction of carbonyl compounds and other functional groups. Dissolving metal reductions and conjugated systems.

SECTION-D

16 Hrs.

Wolf Kishner reduction, Clemmenson reduction, Meerwein pondroff Varley reduction, Wittigs reaction, Addition of Grignards reagent, Organozinc and organolithium reagents to carbonyl and unsaturated carbonyl compounds. Mechanism of condensation reactions involving enolates Aldol, Knoevengel, Claisen, Mannich, Benzoin, Perkin and Stobbe reactions, hydrolysis of erters and amides. Ammonolysis of esters.

References 1. 2. 3. 4. Stereochemistry of Carbon compounds by ernest.L.Eliel, Tata McGraw Hill. Stereochemistry of Organic Compounds , d. Nasipuri, New Age International. Stereochemistry of Organic Compounds , P.S. Kalsi, New Age International. Modern Organic Reactions, H.O. House, Benjamin.

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPER MCH 203 : PHYSICAL CHEMISTRY

Maximum Marks : 70 (i) Semester Paper : 60 (ii) Internal Assessment : 10 Lectures : 65 Time : 3 Hours Pass Marks: 35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five sections: A, B, C, D and E. Sections A, B, C and D will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer questions ( two from each section ) and will be of 1 marks each.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one question from each section : A, B, C and D. Section E is compulsory.

SECTION-A

16 Hrs.

Basics of quantum chemistry : Introduction of quantum chemistry, operators, postulates of quantum chemistry, eigen value and eigen function, normalization and orthogonality, schrodinger wave equation on the basis of postulates of quantum chemistry Application of quantum chemistry to simple systemsTranslational motion of particle : Particle in one dimensional box, particle in three dimensional box-rectangular and cubical box , particle with finite potential barrier,One finite potential barrier, two finite potential barrier, the quantum mechanical tunneling Vibrational motion of particle : Harmonic oscillator obeys Hookes law ,The harmonic oscillator is conserved, the equation for a harmonic oscillator model of a diatomic molecule contains the reduced mass of a molecule, a harmonic oscillator accounts for IR spectrum of a diatomic molecule, physical interpretation of and 2 Rotational motion of particle : Rigid rotator- rotation in one plane , rotation in space. Hydrogen and like atoms : Spherically symmetric potential and the Hamiltonian, spherical coordinates , schrodinger wave equation in terms of r, ,. radial eigen functions, atomic orbitals of hydrogen like atoms, significance of the quantum numbers n, l, m. graphical representation of the orbitals

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

SECTION- B

16 Hrs.

Approximate methods: Variation principle-linear and non linear variation theory, Perturbation theory-Ist and IInd order perturbation, application of variation and perturbation theory to He atom, Molecular orbital theory : LCAO approximation, the H2 + ion, the LCAO MO wave fuction of H2+ ion, electron density and bonding in H2 +, physical representation , bond order, charge density calculation, free valence ,conjugated molecules, Huckel MOT of conjugated systems ,Huckel rule of aromaticity, applications of Huckel MOT to ethylene, butadiene, the extended Huckel theory. Theory of angular momentum : Angular momentum, quantum mechanical operator for angular momentum, ladder operator, eigen function and eigen values of angular momentum using ladder operator, orbital and spin motion, spin angular momentum, addition of angular momentum, coupled and uncoupled representation of angular momentum

SECTION-C

16 Hrs.

Introduction of chemical kinetics : Order and molecularity of reaction ,influence of temperature on reaction rates, Theories of reaction rates : Arrhenius equation and its limitations, collision and absolute reaction rate theory, unimolecular reaction, Lindmann theory, the Hinshelwood theory, the RRK theory ,the RRKM theory, statitstical derivation of rate equation(Eyring equation) ,thermodynamic formulation of reaction rates, free energy of activation ,heat of activation and its relationships with various kinds of activation energies, relationship between stearic factor and entropy of activation, transmission coefficient,

SECTION-D

16 Hrs.

Complex reactions : Parallel, reversible, consuctive, branching, free radical and chain reactions steady state treatment Reaction in solutions : Primary and secondary salt effects effect of polarity and nature of solvent on rate of reaction Catalysis : Introduction , characteristics of catalytic reactions, acid base catalysis , enzyme catalysis, Michaelis Menten equation, effect of temperature on enzyme catalysis, oscillating reactions.

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] Refernces: 1. Kinetics and mechanism by A.A Frost & R.G Pearson, John-Wiley ,& sons Inc.,N.York. 2. Physical Chemistry by P.W. Atkins. 3. Chemical kinetics methods by C.Kalidas, New Age International Publishers. 4. Introduction to Quantum Chemistry ,A.K.Chandra, Tata McGraw Hill. 5. Quantum Chemistry by I.N . Levine, Prentice Hall. 6. Quantum Chemistry by R.K. Prasad. 7. Physical Chemistry by Puri Sharma Pathania 8. Physical Chemistry by Gurdeep Raj 9. Physical Chemistry by Gurthu 10. Quantum Chemistry by Donald A McQuarie

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPERMCH 204 : COMPUTER FUNDAMENTALS AND PROGRAMMING WITH C

Maximum Marks : 70 (i) Semester Paper : 60 (ii) Internal Assessment : 10 Lectures : 65 Time : 3Hours Pass Marks:35%

INSTRUCTIONS FOR THE PAPER-SETTER

The question paper will consist of five Sections A, B, C, D and E. Section A, B, C and D each will have two questions from the respective sections of the syllabus and will carry 12 marks each. Section E will consist of 8 short-answer question (two from each section) and each part will be of 1 marks.

INSTRUCTIONS FOR THE CANDIDATES

Candidates are required to attempt one question from each section : A, B, C and D . Section E is compulsory. SECTION-A 17 Hrs. Computer organization : Hardware, Software, Programming languages with special reference to BASIC, Fortran and C. Binary representation : Binary numbers, Conversion of decimal to binary and binary to decimal, Idea of Octal and hexa-decimal numbers. Problem solving : Problem analysis, Algorithm development, Program Coding, Program Compilation and execution.

SECTION-B

16 Hrs.

Introduction to C : Historical development of C, The C character set, Constants, variables and keywords, Types of C constants and variables, C keywords. C instructions : Type declaration instruction, Arithmetic instructions, Integer and float conversion, Type conversion in assignment, Hierarchy of operations, Writing of a first program in C, Control Instructions in C. Simple problems with sequential structure.

SECTION-C

16 Hrs.

Decision and control structure : The if statement, The if-else statement, The nested if-else statement, Use and hierarchy of logical operators, Conditional operators. Loop control structure : The while loop, The for loop, Nesting of loops, The dowhile loop, Break and continue statements. Case control studies : Decision using switch, The go to statement, Simple problems with Selective and repetitive structures

SECTION-D

16 Hrs

Introduction to functions, Role of functions, Uses of functions, Passing arguments between functions: Call by value, Call by reference.
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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ] Function declaration, Function Prototype. An introduction to Pointers, Pointer arithmetic. Array: An introduction to one Dimensional and multidimensional, Initialization.

References: 1. Let Us C by Yashavant Kanetkar, (BPB Publications, New Delhi). 2. Programming in ANSI by E. Balgurusamy, Tata McGraw-Hill Publishing Co. I.T., New Delhi. 3. Programming with Fortran-77 by Ran Kumar, Tata McGraw-Hill Publishing Co. I.T., New Delhi

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPERMCH 205 : ORGANIC CHEMISTRY PRACTICALS

Maximum Marks : 100 (i) Practical Examination : 80 (ii) Internal Assessment : 20 Time : 6 Hours

1 .Qualitative Organic Analysis: S eparation and Purification of components of binary mixture (solid/solid, solid/liquid, liquid/liquid) on the basis of solubility behaviour and solvent extraction and their identification and conformation by chemical tests and preparation of suitable derivative.

Organic Synthesis: Benzoylation Oxidation Aldol condensation Sandmeyer's reaction Benzfused Heterocycles Cannizzaro's reaction Friedel Crafts reaction Aromatic electrophilic substitution

: : : : : : : :

Hippuric acid Adipic acid/p-Nitrobenzoic acid Dibenzalacetone/Cinnamic acid p-Chlorotoluene Benzimidazole p-Chlorobenzaldehyde as substrate -Benzoylpropionic acid p-Nitroaniline / p-Iodoaniline

The products may be characterized by spectral techniques. References 1. Vogels's Textbook of Practical Organic Chemistry, 5th Edition ELBS (Longman), 1996. 2. Practical Organic Chemistry by F.G. Mann and B.C. Saunders, 5th Edition, Orient Longman Limited, 1986.

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

PAPERMCH 206 : PHYSICAL CHEMISTRY PRACTICALS

Maximum Marks : 100 (i) Practical Examination : 80 (ii) Internal Assessment : 20 Time : 6 Hours

1.To determine the molecular weight of given polymer by viscosity method. 2. To determine the atomic parachors of C,H and O. 3.To compare the cleansing powers of two samples of detergents by surface tension method. 4. . To determine the interfacial tension between two immiscible solvents. 5. To determine the density of given liquids with the help of pyknometer 6.To find out the value of coefficient of expansion for the given liquid with the help of pyknometer. 7. To find out the molar refractivities of homologous series of alcohols and also find out the atomic refractivities of C and H. 8. To find out the molar refractivity of the given solid. 9. To find out the equilibrium constant for the given reaction, KI+I2-KI3 by partition method. 10. To determine the rate constant of the hydrolysis of ethyl acetate catalysed by an acid and also find out the half life period of the reaction. 11. To determine the order of saponification of ethylacetate with NaOH. 12.To study the adsorption of acetic acid on activated charcoal and prove the validity of Freundlich adsorption isotherm.

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[ M.Sc. (CHEMISTRY) PART-I (SEMESTER I & II) ]

SEMINAR
Maximum Marks : 20 Time : Hr.

Every candidate will have to deliver a seminar of 30 minutes duration on a topic which will be chosen by him/her in consultation with the teacher of the department. The seminar will be delivered before the students and teachers of the department. A three member committee ( one coordinator and two teachers of the department of different branches) duly approved by the departmental council will be constituted to evaluate the seminar. The following factors will be taken into consideration while evaluating the candidate. 1. Expression 2. Presentation 3. Depth of the subject matter and answers to the questions.

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