Product Brochure

Lonzas chemical network Diketene and HCN derivatives, heterocycles and basic chemicals catalog
Pharma&Biotech Nutrition Agriculture MaterialsScience PersonalCare
Diketene and HCN derivatives, heterocycles and basic chemicals catalog
Content
About Lonza Introduction Diketene/ketene derivatives
Esters Arylides Alkylamides Pyrazolones Dehydroacetic acid Lonzamon monomers Other diketene derivatives
3 4 6
6 7 8 9 9 10 10
HCN derivatives Heterocycles Basic chemicals Others Alphabetical index
12 14 16 17 18
About Lonza
Lonza is the global leader in the production and support of active pharmaceutical ingredients both chemically and biotechnologically. Biopharmaceuticals are one of the key growth drivers of the pharmaceutical and biotechnology industries. Lonza has strong capabilities in large and small molecules, peptides, amino acids and niche bioproducts which play an important role in the development of novel medicines and healthcare products. In addition, Lonza is a leader in cell-based research, endotoxin detection and cell therapy manufacturing. Furthermore, the company is a leading provider of chemical and biotech ingredients to the nutrition, hygiene, preservation, agro and personal care markets. From 1897 to the present day combining Swiss tradition with global experience, the company has had an enterprising character, adapting its offerings and services to the needs of customers and to changing technologies. Throughout our history, we have maintained a strong culture of performance, results and dependability that is valued by all of our customers. Lonzas cracker in Visp is the back bone of a comprehensive fully backward integrated chemical network. Our product portfolio consists of HCN- and diketene derivatives as well as basic chemicals which are key raw materials and intermediates for many sophisticated applications.
Diketenes/ketenes
Diketene is a colorless liquid produced by dimerization of ketene. It is a highly reactive building block which can be combined with numerous other chemical compounds to make a wide range of products. Because of its high energy content, transport of diketene is forbidden. It is processed further at the site of manufacture. Lonza is one of the worlds leading suppliers of diketene derivatives manufactured in its production facility in Visp, Switzerland. Our diketene derivatives are used in the pharmaceutical, vitamin, agrochemical and pigment industries. The niche markets are in cosmetics, plasticizers, paints. The acetoacyl group in diketene derivatives has a broad functionality which can be used for the production of further products. Lonzas most comprehensive diketene product lines are those made with alcohols (aceto-acetic acid and acrylate derivatives), aliphatic amines (alkylamides) and aromatic amines (arylamides). Lonza uses some of these to produce further components (pyrazolones, aminocrotonates, side chains). The following summary provides an overview of the diketene derivative product groups: Diketene esters (acetoacetates): Major products such as methyl, ethyl, isopropylester of acetoacetic acid are produced in a continuous process and purified by distillation. Minor derivatives are produced batchwise in stirred vessel reactors. The products are used mostly in the dye, agrochemical, pharmaceutical and vitamin industries. Arylamides: A large variety of arylamides are obtained by the reaction of aromatic amines with diketene. Our most important products are AAA, AAOT, AAMX, AAOA, and AAOC; others are made regularly or on special request. These derivatives are used mainly in the production of azo pigments; but also in the dye and agrochemical industries. Alkylamides: Aliphatic amines react with diketene to result in alkylamides. Major products such as monomethyl- or dimethylacetoacetamides are manufactured as aqueous solutions with continuous processes; other derivatives and water-free compounds are produced with batch processes. The (alkyl-) acetoacetamides are used principally in the manufacture of insecticides. The derivatives are also deployed in the pigment, pharmaceutical and polymer industries. DHS/NaDHS: The catalytic dimerization of diketene yields dehydroacetic acid (DHS), which is a solid material. The free acid can be neutralized with sodium hydroxide and is available as the salt NaDHS or its monohydrate NaDHS-H2O. These products are used above all in the manufacture of PVC stabilizers and as preservatives in the cosmetic industries. Acrylic acid esters (acetoacetoxy monomers): Acetoacetoxyethyl methacrylate (AAEMA), the most important product of this group, is made in a multipurpose batch production plant. It is used as a copolymer for coatings and adhesives in emulsion polymerization (waterborne dispersions) or solvent polymerization (high solids), and provides improved mechanical and solvent resistance to water or organic solvents. It also promotes adhesion to metallic, mineral and wood surfaces. Other diketene derivatives: 4-Chloroacetoacetic acid ester is a highly versatile diketene derivative. It can be used in syntheses of various pharmaceutical intermediates. Ketene: Lonza has the specific capability to perform a variety of reactions with ketene. The production of ethyl 4,4,4-trifluoroacetoacetate is one example for such a ketene reaction. For more information about ketene/diketene chemistry and its various derivatives, please ask for specific brochures and related literature or send mail to diketene@lonza.com.
Hydrocyanic acid (HCN)

Hydrogen cyanide is a extremely poisonous colorless or pale-blue liquid that undergoes a wide variety of reactions. Lonza has manufacturing capabilities to offer a solution of hydrogen cyanide in water (hydrocyanic acid) and producing its derivatives. HCN is used in metallurgical and photographic processes. Furthermore, HCN is a starting material for cyanogen chloride, cyanoacetates, cyanohydrins, sodium cyanide, chelating agents and many more. Cyanogen chloride is a functional building block for other Lonza products like cyanuric chloride and malononitrile. The cyanohydrins, give access to a variety of useful organic compounds including the monomer methyl methacrylate, amino acids via the Strecker synthesis, and the chelating agents EDTA and NTA.
Basic chemicals
Beside ketene and HCN chemicals Lonzas cracker related product portfolio also offers a selective number of basic chemicals. The chemicals can be used as starting materials and processed further to yield coatings, colorants, adhesives, medicines, agrochemicals and more.
Icons
Pharma Colorants Agriculture Polymers Nutrition Various
Methyl acetoacetate (MAA)
Ethyl acetoacetate (EAA) C5H10O3
Diketene/ ketene derivatives

Molecular weight CAS RN Minimum assay Minimum stability Melting point ca. Boiling point ca. Density g/cm3 (20C) EU labeling Packaging Transport information
Esters
C5H8O3

116.12 105-45-3 99.0% 2 years 28C 170C 1.077 Xi irritant drums, bulk not restricted

130.14 141-97-9 99.0% 2 years 43C 180C 1.03 drums, bulk not restricted
Isopropyl acetoacetate (IPAA) C7H12O3
Isobutyl acetoacetate (AAisobutyl) C8H14O3
t-Butyl acetoacetate (AA-t-butyl) C8H14O3

144.17 542-08-5 98.5% 2 years 27C 185C 0.998 Xi irritant drums, bulk not restricted

158.20 7779-75-1 98.0% 2 years 20.5C 205C 0.974 drums not restricted

158.20 1694-31-1 98.0% 2 years 38C 71C/15hPa 0.970 drums not restricted
Benzyl acetoacetate (BAA) C11H12O3
N-Benzyl-N-methyl-2-aminoethylacetoacetate (AABME) C14H19NO3
Dodecyl acetoacetate (AAdodecyl) C16H30O3

192.22 5396-89-4 2 years 12C 275C dec. 1.114 Xi irritant drums not restricted

249.31 54527-65-0 95.0% 8 months 175C dec. 1.067 drums not restricted

270.42 52406-22-1 96.0% 23 years 190C/20hPa 0.914 Xi irritant drums not restricted
2-Methoxyethyl acetoacetate Ethyl benzoylacetate-91 (BESethyl-91) C11H12O3

(AAmethoxyethyl)
4-Nitrobenzyl acetoacetate (30% in toluene) (PNBAA 30T) C11H11NO5
C7H12O4

192.22 94-02-0 91.0% 2 years 93C/10Pa drums not restricted

160.16 22502-03-0 97.5% 2 years 118C/26hPa 1.091 T toxic drums not restricted

237.21 61312-84-3 270-330 g/l 9 months F, Xn; R11-38-48/20-63-65-67 iron drums 56.25kg, 187.5kg UN 1993, 3, PG II
Acetoacetanilide (AAA)
Acetoacetanilide, flakes (AAA,flakes) C10H11NO2
Arylides
C10H11NO2

177.20 102-01-2 99.5% 2 years 83.0C Xn harmful paper bags, big bags not restricted

177.20 102-01-2 95.0% 9 months 62.0C Xn harmful big bags not restricted
Acetoacet-o-toluidide (AAOT) C11H13NO2
Acetoacet-m-xylidide (AAMX) C12H15NO2 Pharma Colorants


205.26 97-36-9 99.5% 2 years 89C Xn harmful paper bags, big bags not restricted
Agriculture Polymers Nutrition Various
Acetoacet-o-chloroanilide (AAOC)
Acetoacet-o-anisidide (AAOA) C11H13NO3
Acetoacet-4-chloro-2,5-dimethoxyanilide (ASIRG) C12H14ClNO4

C10H10ClNO2

211.65 93-70-9 99.5% 2 years 103.5C Xn harmful paper bags not restricted


271.70 4433-79-8 98.0% 2 years 104C Xn harmful paper bags not restricted
Acetoacet-5-chloro-2-methoxyanilide (AAMOC) C11H12ClNO3
Potassium N-(acetoacetyl) sulfanilate (AAsulfanil-K) C10H10KNO5S
Alkylamides

241.68 52793-11-0 99.0% 2 years 92C paper bags not restricted

295.36 70321-85-6 96.0% 2 years >300C paper bags, big bags not restricted

N,N-Dimethylacetoacetamide N-Methylacetoacetamide (MMAA) C5H9NO2

(DMAA-80)
N,N-Diethylacetoacetamide (DEAA) C8H15NO2
C6H11NO2

115.13 20306-75-6 70.0% 2 months 110C 1.078 drums, bulk not restricted


Acetoacetamide (AAmid) C4H7NO2
3-Methyl-5-pyrazolone (MP)
Pyrazolones
C4H6N2O

101.11 5977-14-0 98.5% 18 months 52C paper bags not restricted

98.11 108-26-9 99.0% 2 years 217C drums not restricted
3,5-Dimethylpyrazole (DMP)
Dehydroacetic acid (DHS)
C5H8N2
Dehydroacetic acid
C8H8O4
96.13 67-51-6 99.0% 3 years 107C 218C drums not restricted

168.15 520-45-6 99.0% 2 years 109C Xn harmful paper bags not restricted
Dehydroacetic acid, sodium salt

(NaDHS)
Dehydroacetic acid, sodium salt monohydrate (NaDHS-H2O) C8H9O5Na Pharma Colorants
C8H7O4Na
190.13 4418-26-2 99.0% 2 years Xn harmful drums not restricted
208.15 64039-28-7 98.0% 2 years 109C Xn harmful drums not restricted
2-(Acetoacetoxy) ethylmethacrylate
(AAEMA)
Propane-1.1.1-triyltrimethyl tris (acetoacetate) (AATMP) C18H26O9

Lonzamon monomers
C10H14O5
214.21 21282-97-3 95.0% 1 year 60C 100C/1hPa 1.122 Xi irritant drums not restricted
386.4 22208-25-9 92.0% 2 years 30C 300C drums not restricted
Squaric acid (QS)
Diethyl squarate (QS, diethyl) C8H10O4
Other diketene/ketene derivatives
C4H2O4

114.06 2892-51-5 98.5% 2 years 293C 1.82 drums not restricted
170.17 5231-87-8 98.0% 12 months 48C (solidification) 95C/0.1hPa 1.15 T toxic; R21-25-36/37/38-42-43 iron drums UN 2810, 6.1, PG III
Diacetoacet-1,4-phenylenediamide Diacetoacet-o-tolidide (DiAA-o-tolidid) C22H24N2O4

(DiAAphen)
Diacetoacet-2,5-dimethyl-1,4phenylenediamide (DiAA DM) C16H20N2O4
C14H16N2O4
380.45 91-96-3 98.0% 2 years 206C bag-in-box, drums not restricted
10
Diacetoacet-2-chloro-5-methyl-1,4phenylenediamide (DiAA MC) C15H17ClN2O4
Diacetoacet-2,5-dichloro-1,4phenylenediamide (DiAA DC) C14H14Cl2N2O4
Methyl 3-aminocrotonate (ACMe) C5H9NO2
115.13 14205-39-1 98.0% 81C 112C/55hPa Xi irritant drums not restricted
1,4-Butyleneglycolbis (3-aminocrotonate) (BGAC)
Diketene-acetone adduct (DAA) C7H10O3
Thiodiglycolbis (3-aminocrotonate) (TGAC) C12H20N2O4S
C12H20N2O4
256.30 14205-47-1 96.0% 2 years 146C bag-in-box not restricted
142.16 5394-63-8 93.0% 3 months 12C 66C/3mbar 1.094 F flammable drums UN-No.: 1993, 3, PG II
288.37 13560-49-1 96.0% 2 years 88C N environment fibre container UN-No.: 3077, 9, PG III
2,5-Dimethyl-2,4-dihydropyrazol-3-on (DMPO) C5H8N2O
Ethyl 4-chloroacetoacetate (CAAEt) C6H9ClO3 Pharma Colorants

112.13 2749-59-9 >98.0% 117118C 105115C/8hPa 1.14 Xi irritant not restricted
164.59 638-07-3 97.0% 1 year 8.5C 220C 1.212 T toxic, N environment drums UN-No.: 2922, 8, PGII
11
Ethyl 4,4,4-trifluoroacetoacetate
(ETFAA)
Methyl 3,3-dimethoxypropanoate
(PRSMe,DM)
(E)-Methyl 3-methoxyacrylate
(E-MMA)

C6H7F3O3
C6H12O4
C5H8O3
184.12 372-31-6 98.0% 6 months 39C 131C 1.2586 Xn harmful drums not restricted

148.16 7424-91-1 98.0% 12 months <65C 77C/26mbar 1.06 not restricted

116.12 34846-90-7, 5788-17-0 (linear structure) 98.0% 2 years 23C 95C/100hPa 1.07 not restricted
Methyl 4-methyl-3-oxopentanoate
(OPMe, 4-methyl)
C7H12O3
Pharma Colorants
144.17 42558-54-3 98.0 % 12 months 75C 192C 1.01 drum or iso-container not restricted
Adenine
Cyanuric chloride A (CC A) C3Cl3N3
Cyanuric chloride AS (CC AS) C3Cl3N3
HCN derivatives
C5H5N5

135.13 73-24-5 98.0102.0% 2 years 360C drums not restricted

184.41 108-77-0 99.5% 6 months 145.0147.0C 193C/1013hPa bags in box not restricted

184.41 108-77-0 99.5% 6 months 145.0147.0C 193C/1013hPa big bags not restricted
12
2-Methoxyethyl cyanoacetate Allyl cyanoacetate (CNESallyl) C6H7NO2 Butyl cyanoacetate (CNESbutyl) C7H11NO2
(CNES methoxyet)
C6H9NO3

125.13 13361-32-5 99.0% 2 years 40C 8990C/5 hPa T toxic; R25 drums 200kg UN 3276, 6.1, PG III

141.17 5459-58-5 99.0% 2 years 109.0C/13.0hPa 0.9981.002 drums 200kg not restricted

143.14 10258-54-5 99.0% 2 years 257C/1000hPa iron drums 200kg, container not restricted
Malononitrile (85% in methanol) Chlorosulfonyl isocyanate (CSI) CClNO3S Malononitrile (MDN) C3H2N2
(MDN)
C3H2N2 ; CH4O

141.53 1189-71-5 99.0100.3% 12 months 1060C 1.626 C corrosive; R14-20/21/22-34 drums UN 3264, 8, PG I

66.06 109-77-3 99.0% 18 months 218219C 1.0494 (35C) T toxic, N environment; R23/24/25-50/53 drums UN 2647, 6.1, PG ll

98.11 109-77-3 83.586.5% 2.5 months 19.5C 1.011 (35C) T,N; R10-23/24/25-39/23/24/25-50/53 drums, rail tank wagon UN 2929, 6.1 (3), PG ll
3-Aminocrotononitrile (Diacetonitril) C4H6N2
Sodium dicyanamide (Na-dicyanamide) C2N3Na
1,1,3,3-Tetramethylguanidine (TMG) C5H13N3

82.11 1118-61-2 96.0% 8 months 4067C 0.9520 (77C) drums not restricted

89.03 1934-75-4 97.0% 2 years >260C drums, BB packaging on request not restricted

115.18 80-70-6 99.0% 1 year 162C/1013hPa 0.92 drums, bulk not restricted
13
Akolidine 10 (Pyridine, alkyl derivatives)
Heterocycles
All akolidines contain the following components:

68391-11-7 0.9780.990 iron drum, bulk not restricted


2-Amino-4,6-dimethoxypyrimidine
(ADMP)
2-Chloro-4,6-dimethoxypyrimidine
(DMP, 2-Chlor)
2-(5-Ethyl-2-pyridyl)ethanol
(PRD-2-etol, 5-Et)
C6H9N3O2
C6H7ClN2O2
C9H13NO



151.21 5223-06-3 95.0% 2 years 45C 147149C 1.042 iron drum 200kg not restricted
5-Ethyl-2-methylpyridine (MEP) C8H11N
6-Hydroxynicotinic acid (NS,6-Hydroxy) C6H5NO3
Sodium nicotinate (NS-Na) C6H4NNaO2

121.18 104-90-5 1 year 70.9C 178.3C 0.9180.921 iron drum 180kg not restricted

139.11 5006-66-6 97.5100.3% 23 years 314 316C drums not restricted

14
Niacin min. 99.5% (NS fg) C6H5NO2
Niacinamide USP (NSA USP) C6H6N2O
Meta metaldehyde (META tc) C8H16O4

123.11 59-67-6 99.5100.3% 3 years 234.0237.0C paper bags, big bags not restricted

122.13 98-92-0 99.0101.0% 3 years 128.0131.0C bag-in-box 20kg not restricted

176.21 108-62-3 98.099.8% 3 years (10C) 246C bag-in-box 25kg not restricted
Paraldehyde (PARA) C6H12O3
2-Picoline (Picoline,2) C6H7N
4-Picoline (Picoline,4) C5H7N

132.16 123-63-7 99.5% 60 days 0.9930.997 kg/l (20C) iron drum 200kg, bulk not restricted

93.13 109-06-8 99.0% 2 years 66.8C 125130C iron drum 180 kg, bulk not restricted

93.13 108-89-4 >98.0% 3.6C 145.4C 0.954 T toxic; R10, R20/22, R24, R36/37/38 not restricted
Pyrimidine (<0.5% water)

(Pyrimidine W<0.5)
4,6-Dimethoxy-2-[(phenoxycarbonyl)amino]pyrimidine
(ADMP-carbamat)
C4H4N2
C13H13N3O4
Pharma Colorants

80.09 289-95-2 98.5100.0% 2 years 2022C 12224C 1.016 drums not restricted

275.26 89392-03-0 97.0101.0% 2 years 120122C >250C drums not restricted
15
Acetaldehyde (AcAl)
Acetic acid (glacial) (ES 99) C2H4O2
Acetic anhydride (ESanhydrid) C4H6O3
Basic chemicals
C2H4O

44.05 75-07-0 99.5% 1 year 123.5C 21C 0.7840.786 kg/l (15C) drums, bulk not restricted

60.05 64-19-7 99.5100.0% 2 years 15.816.3C 113115C/933hPa 1.050 g/ml (20C) drum 200kg, bulk not restricted
102.09 108-24-7 99.5% 2 years 73C 1.0820 drums 200 kg, rail tanker not restricted
Ammonia techn. (Ammonia tc) NH3
Ammonia aqueous (Ammonia 24) approx. 24.524.9% chemically pure NH3
Nitric acid 65% HNO3

17.03 7664-41-7 99.8% 2 years 33.4C/1013hPa 0.609 rail tanker not restricted

17.03 1336-21-6 24.524.9% 2 years 0.91500.9110 g/ml (15C) drums, road and rail tanker not restricted
63.01 7697-37-2 65.065.5% 33C 121C/1013hPa rail tanker not restricted
Nitrosylsulfuric acid 40%(SS,Nitrosyl40) HNO5S
Malonic acid (MA) C3H4O4

127.08 7782-78-7 39.540.5% 2 years 123C 333C 1.893 rail tanker not restricted

104.06 141-82-2 99% 1 year 134C (Mettler) Xi irritant; R36 bags not restricted
16
2,6-Diethyl-4-methylaniline (DEMA)
2,6-Diisopropylaniline (DIPA) C12H19N
4,4-Dimethoxy-butan-2-one (DMB) C6H12O3
Others
C11H17N

163.26 24544-08-9 >98.0% 1 year 12C 7C 0.945 Xn harmful; R21/22 steel drums, bulk not restricted

177.29 24544-04-5 92.0% 1 year 45C 257C/1013mbar 0.940 R52/53 iron drum 180kg, bulk not restricted

132.16 5436-21-5 >92.0% 2 years 83 81C 16971C 0.9977 drums, bulk not restricted
Valeronitrile (VN) C5H9N Pharma Colorants

Molecular weight CAS RN Minimum assay Minimum stability Melting point ca. Boiling point ca. Density g/cm3 (20C) EU labeling Packaging Transport information 83.13 110-59-8 99.5% 2 years 139141C/1013hPa 0.7990 drums, bulk not restricted
17
Alphabetical index

Page Product Abbreviation Page Product Abbreviation

6 1 16 16 9 7 8 8 7 8 8 7 10 12 14 14 14 13 14 13 16 10
A
Acetaldehyde Acetic acid (glacial) Acetic anhydride Acetoacetamide Acetoacetanilide Acetoacet-4-chloro-2,5-dimethoxyanilide Acetoacet-5-chloro-2-methoxyanilide Acetoacet-m-xylidide Acetoacet-o-anisidide Acetoacet-o-chloroanilide Acetoacet-o-toluidide 2-(Acetoacetoxy)ethyl methacrylate Adenine Akolidine 10 Akolidine 11 Akolidine 12 Allyl cyanoacetate 2-Amino-4,6-dimethoxypyrimidine 3-Aminocrotononitrile Ammonia aqueous approx. 24.524.9% chemically pure Ammonia techn. AcAl ES 99 ESanhydrid AAamid AAA ASIRG AAMOC AAMX AAOA AAOC AAOT AAEMA Adenine Akolidine 10 Akolidine 11 Akolidine 12 CNESallyl ADMP Diacetonitril Ammonia 24 Ammonia tc

9 9 9 11 11 10 10 10 8 10 16 11 16 16 15 8 11 9 6
D
Dehydroacetic acid Dehydroacetic acid sodium salt monohydrate Dehydroacetic acid sodium salt Diacetoacet-2-chloro-5-methyl-1,4-phenylenediamide Diacetoacet-2,5-dichloro-1,4-phenylenediamide Diacetoacet-2,5-dimethyl-1,4-phenylenediamide Diacetoacet-1,4-phenylenediamide Diacetoacet-o-tolidide N,N-Diethylacetoacetamide Diethyl squarate 2,6-Diethyl-4-methylaniline Diketene-acetone adduct 2,6-Diisopropylaniline 4,4-Dimethoxy-butan-2-one 4,6-Dimethoxy-2-[(phenoxy-carbonyl)amino]pyrimidine N,N-Dimethylacetoacetamide 2,5-Dimethyl-2,4-dihydro-pyrazol-3-on 3,5-Dimethylpyrazole Dodecyl acetoacetate DHS NaDHS-H2O NaDHS DiAA MC DiAA DC DiAA DM DiAAphen DiAA-o-tolidid DEAA QS, diethyl DEMA DAA DIPA DMB (ADMP-carbamat) DMAA DMPO DMP AAdodecyl

6 7 11 14 14 12

6 6 13 6 11
B
Benzyl acetoacetate N-Benzyl-N-methyl-2-aminoethylacetoacetate Butyl cyanoacetate t-Butyl cyanoacetate 1,4-Butyleneglycolbis(3-aminocrotonate) BAA AABME CNESbutyl AA-t-butyl BGAC
E Ethyl acetoacetate Ethyl benzoylacetate Ethyl 4-chloroacetoacetate 5-Ethyl-2-methylpyridine 2-(5-Ethyl-2-pyridyl)ethanol Ethyl 4,4,4-trifluoroacetoacetate H
6-Hydroxynicotinic acid
EAA BESethyl CAAEt MEP PRD-2-etol, 5-Et ETFAA

4 1 13 12 12
C
2-Chloro-4,6-dimethoxypyrimidine Chlorosulfonyl isocyanate Cyanuric chloride A Cyanuric chloride AS DMP, 2-Chlor CSI CC A CC AS

14
NS,6-Hydroxy

6 6
I Isobutyl acetoacetate Isopropyl acetoacetate M

Malonic acid Malononitrile (85% in methanol) Malononitrile Meta metaldehyde 2-Methoxyethyl acetoacetate 2-Methoxyethyl cyanoacetate 3-Methyl-5-pyrazolone Methyl 3,3-dimethoxypropanoate Methyl 3-aminocrotonate (E)-Methyl 3-methoxyacrylate Methyl 4-methyl-3-oxopentanoate N-Methylacetoacetamide Methyl acetoacetate
AAisobutyl IPAA

6 1 13 13 15 7 13 9 12 11 12 12 8 6
MA MDN MDN META tc AAmethoxyethyl CNES methoxyet MP PRSMe,DM ACMe E-MMA OPMe, 4-methyl MMAA MAA
18
Page Product
Abbreviation

5 1 15 16 7 16
N
Niacin min. 99.5% Niacinamide USP Nitric acid 65% 4-Nitrobenzyl acetoacetate (30% in toluene) Nitrosylsulfuric acid 40% NS fg NSA USP PNBAA 30T SS,Nitrosyl40

5 1 15 15 8 10 15
P Paraldehyde 2-Picoline 4-Picoline Potassium N-(acetoacetyl)sulfanilate Propane-1,1,1-triyltrimethyl tris(acetoacetate) Pyrimidine (<0.5% water) S Sodium dicyanamide Sodium nicotinate Squaric acid T 1,1,3,3-Tetramethylguanidine Thiodiglycolbis(3-aminocrotonate) V Valeronitrile
PARA Picoine,2 Picoline,4 AAsulfanil-K AATMP Pyrimidine W<0.5

3 1 14 10
Na-dicyanamide NS-Na QS

3 1 11
TMG TGAC

16
VN
www.lonza.com
Administration/ technical service

Switzerland
Lonza Ltd Muenchensteinerstrasse 38 4002 Basel Tel + 41 61 316 81 11 contact@lonza.com
Sales offices
Europe
Lonza Benelux BV Aluminiumstraat 1 PO Box 3148 NL-4823 AL Breda Tel +31 76 542 51 00 contact.nl@lonza.com Lonza Biotec sro Okruzn 134 CZ-281 61 Koum Tel +42 0321 738 654 contact.cz@lonza.com Lonza France Srl 55, rue Aristide Briand FR-92309 Levallois-Perret Cedex Tel +33 1 40 89 99 00 contact.fr@lonza.com Lonza Cologne GmbH Nattermannallee 1 DE-50829 Kln Tel +49 221 99 1990 info.cologne@lonza.com Lonza Ltd Representation Office Dunahz III. lpcshz II. em 2 Borros tr 7 HU-1095 Budapest IX Tel +36 1 215 94 19 contact.hu@lonza.com Lonza Ltd Representation Office ul. Smolenskiego 4 m 15 PL-01-698 Warsaw Tel +48 22 833 87 45 contact.pl@lonza.com Lonza Ibrica S.A.U. (Unipersonal) Va Augusta, n18, 2a Pta, izda ES-08006 Barcelona Tel +34 93 238 54 60 contact.es@lonza.com Lonza Biologics plc Suite 3, Building A The Courtyard Severn Drive Tewkesbury Business Park GB-Tewkesbury GL20 8GD Tel +44 1684 292 728 contact.uk@lonza.com
Asia
Lonza Guangzhou Ltd 39, Jinhui Road Haizhu District CN-Guangzhou 510288 Tel +86 20 8433 8998 contact.cn@lonza.com Lonza Japan Ltd Kyowa Shinkawa Bldg 8F 2-20-8, Shinkawa, Chuo-ku JP-Tokyo 104-0033 Tel +81 3 5566 0612 contact.jp@lonza.com
USA
Lonza Inc. 90 Boroline Road Allendale, NJ 07401 Tel +1 201 316 9200 contact.allendale@lonza.com
The information contained herein is believed to be correct and corresponds to the latest state of scientific and technical knowledge. However, no warranty is made, either expressed or implied, regarding its accuracy or the results to be obtained from the use of such information. Some products may not be available in all markets or for every type of application. Any user must make his own determination and satisfy himself that the products supplied by Lonza Group Ltd and the information and recommendations given by Lonza Group Ltd are (i) suitable for intended process or purpose, (ii) in compliance with environmental, health and safety regulations, and (iii) will not infringe any third partys intellectual property rights. 2011 Lonza Ltd

Product Brochure

Enviado por

Dados do documento

Descrição original:

Título original

Direitos autorais

Formatos disponíveis

Compartilhar este documento

Compartilhar ou incorporar documento

Opções de compartilhamento

Você considera este documento útil?

Este conteúdo é inapropriado?

Direitos autorais:

Formatos disponíveis

Product Brochure

Enviado por

Direitos autorais:

Formatos disponíveis

Lonzas chemical network Diketene and HCN derivatives, heterocycles and basic chemicals catalog

Pharma&Biotech Nutrition Agriculture MaterialsScience PersonalCare

Diketene and HCN derivatives, heterocycles and basic chemicals catalog

HCN derivatives Heterocycles Basic chemicals Others Alphabetical index

Diketene and HCN derivatives, heterocycles and basic chemicals catalog

Hydrocyanic acid (HCN)

Diketene and HCN derivatives, heterocycles and basic chemicals catalog

Methyl acetoacetate (MAA)

Ethyl acetoacetate (EAA) C5H10O3

Diketene/ ketene derivatives

Isopropyl acetoacetate (IPAA) C7H12O3

Isobutyl acetoacetate (AAisobutyl) C8H14O3

t-Butyl acetoacetate (AA-t-butyl) C8H14O3

Benzyl acetoacetate (BAA) C11H12O3

N-Benzyl-N-methyl-2-aminoethylacetoacetate (AABME) C14H19NO3

Dodecyl acetoacetate (AAdodecyl) C16H30O3

2-Methoxyethyl acetoacetate Ethyl benzoylacetate-91 (BESethyl-91) C11H12O3

4-Nitrobenzyl acetoacetate (30% in toluene) (PNBAA 30T) C11H11NO5

192.22 94-02-0 91.0% 2 years 93C/10Pa drums not restricted

Acetoacetanilide, flakes (AAA,flakes) C10H11NO2

Acetoacet-o-toluidide (AAOT) C11H13NO2

Acetoacet-m-xylidide (AAMX) C12H15NO2 Pharma Colorants

Agriculture Polymers Nutrition Various

Diketene and HCN derivatives, heterocycles and basic chemicals catalog

Acetoacet-o-anisidide (AAOA) C11H13NO3

Acetoacet-4-chloro-2,5-dimethoxyanilide (ASIRG) C12H14ClNO4

Diketene/ ketene derivatives

Acetoacet-5-chloro-2-methoxyanilide (AAMOC) C11H12ClNO3

Potassium N-(acetoacetyl) sulfanilate (AAsulfanil-K) C10H10KNO5S

241.68 52793-11-0 99.0% 2 years 92C paper bags not restricted

N,N-Dimethylacetoacetamide N-Methylacetoacetamide (MMAA) C5H9NO2

N,N-Diethylacetoacetamide (DEAA) C8H15NO2

Acetoacetamide (AAmid) C4H7NO2

101.11 5977-14-0 98.5% 18 months 52C paper bags not restricted

98.11 108-26-9 99.0% 2 years 217C drums not restricted

Dehydroacetic acid (DHS)

96.13 67-51-6 99.0% 3 years 107C 218C drums not restricted

Dehydroacetic acid, sodium salt

Dehydroacetic acid, sodium salt monohydrate (NaDHS-H2O) C8H9O5Na Pharma Colorants

190.13 4418-26-2 99.0% 2 years Xn harmful drums not restricted

208.15 64039-28-7 98.0% 2 years 109C Xn harmful drums not restricted

Agriculture Polymers Nutrition Various

Diketene and HCN derivatives, heterocycles and basic chemicals catalog

Propane-1.1.1-triyltrimethyl tris (acetoacetate) (AATMP) C18H26O9

Diketene/ ketene derivatives

386.4 22208-25-9 92.0% 2 years 30C 300C drums not restricted

Squaric acid (QS)

Diethyl squarate (QS, diethyl) C8H10O4

Other diketene/ketene derivatives

114.06 2892-51-5 98.5% 2 years 293C 1.82 drums not restricted

Diacetoacet-1,4-phenylenediamide Diacetoacet-o-tolidide (DiAA-o-tolidid) C22H24N2O4

Diacetoacet-2,5-dimethyl-1,4phenylenediamide (DiAA DM) C16H20N2O4

380.45 91-96-3 98.0% 2 years 206C bag-in-box, drums not restricted

276.29 24731-73-5 98.5% 2 years 171C paper bags not restricted

304.38 24304-50-5 98.0% 2 years 232C paper bags not restricted

Diacetoacet-2-chloro-5-methyl-1,4phenylenediamide (DiAA MC) C15H17ClN2O4

Diacetoacet-2,5-dichloro-1,4phenylenediamide (DiAA DC) C14H14Cl2N2O4

Methyl 3-aminocrotonate (ACMe) C5H9NO2

324.77 41131-65-1 97.0% 5 years 192C paper bags not restricted

345.18 42487-09-2 97.0% 5 years 197C paper bags not restricted

115.13 14205-39-1 98.0% 81C 112C/55hPa Xi irritant drums not restricted

1,4-Butyleneglycolbis (3-aminocrotonate) (BGAC)

HCN derivatives Heterocycles Basic chemicals Others Alphabetical index

63.01 7697-37-2 65.065.5% 33C 121C/1013hPa rail tanker not restricted