Adrenal-Pro + Thyroid Support .

L-Tyrosine

800 mg

Pantothenic acid (B5, calcium d-pantothenate) 500 mg Ashwagandha extract 1.5% withanolides Schisandra extract 1.6% schisandrins Siberian ginseng extract 0.8% eleutherosides Rhodiola extract 3% rosavins Astralagus extract 0.3% astragalosides Vitamin B6 (pyridoxine HCl) 400 mg 300 mg 300 mg 200 mg 152 mg 60 mg

In four vegetable capsules daily. GMO free, no binders, no fillers. 120ct. Purity code: 195 270

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Adrenal-Pro + Thyroid Support is a completely natural product formulated to enhance health by

supporting the adrenal and thyroid glands, reducing stress and fatigue, increasing energy, and providing an improved sense of well being.

Are you constantly

having a hard time waking up in the morning? tired and exhausted and finding your fatigue is not relieved by sleep? feeling stressed and easily irritated by little things? light-headed when standing up quickly? craving salt or salty foods? getting frequent colds or flus? lacking energy especially in the mornings, as well as midday between 3 to 5pm? needing coffee or stimulants to get you through your day? experiencing a lower libido? struggling with pronounced PMS? forgetting things or experiencing foggy thinking? finding that everything seems to require more effort?

If you are, then you may be suffering from adrenal fatigue. Adrenal fatigue refers to a common disorder in which the adrenal glands function at a very low level. It can lead to people feeling deeply exhausted and burnt out. Adrenal-Pro + Thyroid Support is a premium formulation that delivers nutrients necessary for dramatically improving mood and energy, helping the body to cope with stress, reducing the effects of aging and boosting the immune system. Adrenal-Pro + Thyroid Support may be helpful for: adrenal fatigue stress reduced energy or exhaustion lowered immunity PMS hypoglycemia decreased libido diminished mood poor physical and mental performance

Note: This product contains natural ingredients that have demonstrated an ability to support adrenal and thyroid health. It is not intended to treat, prevent or cure any Schedule A disease including anxiety states, diabetes, heart disease, hypertension, obesity, thyroid disease or sexual impotence.

What are the Adrenals and What Do They Do?

The adrenal glands are two small glands, each the size of a grape, located above the kidneys. They are responsible for our bodys fight-or-flight response and they help the body to cope with stress. Each adrenal gland has two compartments, the inner and outer cortex. The inner adrenal cortex regulates the secretion of the hormones epinephrine and nor epinephrine, both of which are responsible for the bodys fight-or-flight response. The outer adrenal cortex is responsible for producing three major hormones: cortisol (a major stress hormone, a natural glucocorticoid or steroid) aldosterone (responsible for sodium and water retention) DHEA (a hormone related to the area of the adrenals that produces the sex hormones)

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What is Adrenal Fatigue?

Adrenal fatigue is a common disorder that affects millions of people throughout North America. As described earlier, the adrenals are our fight-or-flight glands that help us to deal with stress, either immediate or chronic. Prolonged or overly intense stress (physical, mental or emotional) can lead to adrenal fatigue. For example, adrenal fatigue may develop as a result of chronic emotional stress or worry, long hours of work, surgery, poor nutrition, regular consumption of alcohol or medications or chemotherapy. Adrenal fatigue is the consequence of the adrenal glands no longer being able to adequately meet the constant demands to perform. In our high stress culture, the bodys fight-or-flight response is activated so often that eventually our adrenals become depleted and exhausted and fail to function efficiently.

Additional Signs and Symptoms of Adrenal Fatigue include:

mild depression increased effort to perform daily tasks decreased ability to handle stress dry and thin skin hypoglycemia low body temperature nervousness palpitations unexplained hair loss alternating constipation and diarrhea

Cortisol and Its Functions

Cortisol is an important hormone involved in the stress response. It also helps to regulate glucose metabolism, blood pressure, the immune system, liver detoxification and inflammation. When the body is under stress, cortisol will be released. Cortisol, once released, will give the body a quick burst of energy for combat, heightened memory functions and increased immunity. It also helps to maintain the homeostasis (balance and normal functioning) under stress. In our high stress culture, the bodys fight-or-flight response is activated so often that it does not always have a chance to return to normal. This results in chronic stress and chronically high levels of cortisol in the body. Prolonged elevation of cortisol in the bloodstream can have a negative impact on our health such as: lowered immunity levels impaired cognitive performance suppressed thyroid function blood sugar imbalances decreased bone density decreased muscle tissue elevated blood pressure elevated cholesterol increased abdominal fat (which is associated with increased risk of cardiovascular diseases like heart attack or stroke)

Aldosterone and Its Functions

Aldosterone is a hormone that helps balance minerals within the cells of our body, especially sodium, magnesium and potassium, and the fluid within our bloodstream, cells and tissues. It also assists in the regulation of blood pressure. Stress increases the release of aldosterone, causing sodium retention (leading to water retention) and the loss of two important minerals: potassium and magnesium. However, prolonged fatigue can eventually lead to a reduction in aldosterone and a loss of sodium in the body. Salt (sodium) craving is therefore a common symptom in adrenal fatigue.

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2009 CanPrev Natural Health Products Ltd. 123 Sheppard Ave. E., Toronto ON M2N 3A5

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DHEA and Its Functions

The adrenal cortex also produces small amounts of several of the sex hormones. One of the major sex hormones it produces is DHEA. DHEA is a precursor in the manufacturing of many other hormones such as: estrogen, testosterone, progesterone and cortisol. These hormones are used for energy, vitality and reproduction. Additionally, DHEA plays a major role in stress control. Stress stimulates the body to secrete both cortisol and DHEA. DHEA interacts with cortisol to maintain a balance between them. An imbalance between the two can lead to stress disorders. DHEA has a dampening or calming effect on stress. Thus, the body is usually able to terminate the stress response. However, its success at doing so is dependent upon the amount of available DHEA. Adrenal fatigue often presents itself with decreased levels of DHEA making it very difficult for the body to calm itself down.

Medicinal Ingredients
L-Tyrosine is the vitamin form of the amino acid tyrosine. Amino acids play a central role in the body both as building blocks of proteins and as intermediaries in metabolism. The body makes tyrosine from phenylalanine, which is an amino acid found in beef. Tyrosine serves as a precursor for the synthesis of various hormones including thyroid and pituitary hormones and many of the hormones involved in the stress response. It is also a very important neurotransmitter. Supplementation with L-tyrosine is known to help in the management of various forms of stress, both physical and psychological, as well as sleep deprivation. Some practitioners will recommend L-tyrosine as being helpful for weight loss and improving moods. Pantothenic acid (Vitamin B5, calcium d-pantothenate) is one of eight water-soluble B vitamins. Vitamin B5 is critical to the manufacture of red blood cells as well as sex and stress-related hormones produced in the adrenal glands. It is sometimes referred to as the anti-stress vitamin because it is believed to enhance the activity of the immune system and improve the bodys ability to withstand stressful conditions. Pantothenic acid is also essential for the conversion of fat and sugar into energy. Pantothenic acid is present in most cells in the body but is found in higher amounts in the adrenals because so much energy is required to produce all of the adrenal hormones. Ashwagandha (Withania somnifera) commonly referred to as Indian Ginseng, has been an important herb in the Ayurvedic and indigenous medical systems for thousands of years. Ashwagandha root contains flavonoids and many active ingredients of the withanolide class. Several studies have demonstrated that Ashwagandha has anti-stress, antioxidant, mind-boosting, immune- and thyroid- enhancing and rejuvenating properties. Schisandra extract is a traditional Chinese Herb that possesses adaptogenic properties and supports optimal adrenal function. It enhances the immune system through its antioxidant effects and is believed to promote longevity. It has the ability to increase the energy supply to the brain and body, thus aiding in cognitive function and forgetfulness. In Chinese medicine, it is frequently used to combat fatigue and alleviate stress. Siberian ginseng (Eleutherococcus senticosus) is a medicinal herb used in Traditional Chinese Medicine for increasing stamina, boosting the immune system and increasing longevity. Eleutherosides, the main active components found in Siberian ginseng, are responsible for the plants adaptogenic activity. Scientific research on Siberian ginseng conducted in Russia supports the use of this herb to maintain health and generally strengthen the system. Siberian ginseng may help the body deal with physically and mentally stressful exposures such as heat, cold, physical exhaustion, viruses, bacteria, chemicals, extreme working conditions, noise and pollution. By strengthening the system, it may also help prevent illness. Rhodiola rosea also known as Roseroot, is a traditional folk remedy used to increase physical endurance, work productivity, longevity and resistance to high altitude sickness and to treat fatigue, depression, infections and nervous system disorders. Recent scientific research confirms that rhodiola has adaptogenic properties (an ability to increase resistance to stressors). Astragalus extract (Astragalus membranaceus) has been used in Traditional Chinese Medicine for thousands of years, often in combination with other herbs, to strengthen the body against disease and stress. It contains antioxidants, which protect cells against damage caused by free

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2009 CanPrev Natural Health Products Ltd. 123 Sheppard Ave. E., Toronto ON M2N 3A5

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radicals (by-products of cellular energy). It has been prescribed for centuries for general weakness or chronic illness and to increase overall vitality. Vitamin B6 (pyridoxine HCL) also called pyridoxine, is one of eight water-soluble B vitamins. Pyridoxine is considered to be an anti-stress vitamin because it is believed to enhance the activity of the immune system and improve the bodys ability to withstand stressful conditions. In addition, Vitamin B6 is an important co-factor for a large number of enzyme pathways in the adrenal glands and almost every body system relies on this vitamin for optimal function. Some important enzymes that require Vitamin B6 include those that are responsible for amino acid (protein) metabolism, the formation of essential fatty acids and the formation of certain neurotransmitters. Vitamin B6 also helps the body to properly assimilate proteins and fats.

Cautions/Warnings for Adrenal Pro + Thyroid Support

As with any natural health product, you should consult a health care practitioner on the use of this product especially if you are taking any medication including antibiotics, dopamine, anti-hypertensives, anti-psychotics, anti-coagulants, birth control pills or thyroid hormones or if you have any medical condition including diabetes, hyperthyroidism, Graves Disease or an auto-immune disorder.

Specific Interactions/Cautions
Vitamin B6 is one of the few water-soluble vitamins that can become toxic if taken in large or moderate doses over a long period of time. Chronic intake of over 500 mg of B6 per day can result in toxicity if taken daily for many months or years with reports of doses as low as 150 mg per day causing problems (although the problem seems to be with the liver breaking down large doses at once therefore spreading the doses into three 50mg doses throughout the day would likely not cause a problem).

Frequently Asked Questions

Who should take Adrenal-Pro + Thyroid Support ? Our high stress culture puts many demands on the bodys stress response particularly our adrenal and thyroid glands. Anyone who may be suffering from chronic stress, or looking for natural support for general well being should consider taking Adrenal-Pro + Thyroid Support. What is the best way to take Adrenal-Pro + Thyroid Support? You should take two (2) capsules of Adrenal-Pro + Thyroid Support twice daily with food. Take two (2) capsules in the morning and two (2) capsules at night. If you find that taking the two (2) at night keeps you awake then it is recommended to take the second dose earlier in the afternoon. How does Adrenal-Pro + Thyroid Support work? Adrenal-Pro + Thyroid Support is specially formulated to support both the adrenal and thyroid glands, increase energy, reduce stress and fatigue and provide an improved sense of well being. Each medicinal ingredient in Adrenal-Pro + Thyroid Support was selectively chosen for its ability to enhance adrenal and thyroid gland functioning. Does Adrenal-Pro + Thyroid Support have any adverse effects? No known adverse effects have been reported. However, as with any natural health product you should consult a health care practitioner on the use of this product. A few individuals may experience mild stomach discomfort or queasiness if the product is taken on an empty stomach. It is always recommended to be taken with food. Im on medication for a low functioning thyroid, can I still take Adrenal-Pro + Thyroid Support? Adrenal-Pro + Thyroid Support is formulated to support the adrenal and thyroid glands. It contains medicinal ingredients which may increase thyroid hormones and may have an additive effect when combined with thyroid medications such as: Synthroid, Levoxyl, and Levothroid. You should consult with your health care practitioner prior to consuming Adrenal-Pro + Thyroid Support. You and your health care practitioner can best determine if you could benefit from Adrenal-Pro + Thyroid Support.

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What does adaptogenic mean? Stress adaptation is the bodys ability to respond to a stressor with little or no prolonged stress hormone reaction. Adaptogenic herbs enhance the ability of the body to resist stressors and are often called the great equalizers. Adaptogens exert a normalizing influence on the body by neither overstimulating nor inhibiting normal body function and providing a generalized tonifying effect. How long will I need to take Adrenal Pro + Thyroid Support? The recommended length of time to take Adrenal Pro + Thyroid Support is approximately three (3) months. It takes a long time for the body to recover and restore itself after periods of prolonged or intense stress. If you feel you need to take Adrenal Pro + Thyroid Support for longer than three months, then you would be advised to consult with a health care practitioner to further investigate your ongoing fatigue. After stopping Adrenal Pro + Thyroid Support you may restart the supplement if you anticipate that you will be going through future periods of stress like moving, starting a new job, or traveling.

References
Balch, Phyllis (2002). Prescription for Herbal Healing. Avery Publishing, New York. Chen, Judy T., Robert Wesley, Robert Shamburek, et al. Meta-Analysis of Natural Therapies for Hyperlipidemia: Plant Sterols and Stanols versus Policosanol. Pharmacotherapy, Volume 25, Number 2, 2005. Das, UN. Folic acid says NO to vascular diseases. Nutrition, 2003 Jul-Aug: 19(7-8); 686-92 Garlic [Monograph] www.naturaldatabase.com. P 1-8. Haas, Elson m. Staying Healthy with Nutrition. The Complete Guide to Diet & Nutritional Medicine. Celestial Arts, Berkeley, California. Hoffmann, D. Hawthorn: The Heart Helper. Alternative and Complementary Therapies. April/May 1995. Holub, Darren J. and Bruce J. Holub. Omega-3 fatty acids from fish oils and cardiovascular disease. Molecular and Cellular Biochemistry 263: 217-225, 2004. Lust, John (2005). The Herb Book. Beneficial Books, New York. Murray, Michael T. (1996). Encyclopedia of Nutritional Supplements. Prima Health Publishing, California. Notoginseng [Monograph] www.naturaldatabase.com. P 1-2. Riemersma RA, et al Tea flavonoids and cardiovascular health. Q J Med 2001; 94:277-282 Zimmerman, Marcia and Jayson Kroner (2006). 7-Syndrome Healing. Supplement Essentials for the Mind and Body. Nutrition Solution Publishing, California, USA

For more information call 888 226 7733 or visit adrenal.ca

2007 CanPrev Natural Health Products Ltd. 123 Sheppard Ave. E., Toronto ON M2N 3A5

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