CELL DIVISION

Mitosis in Animal Cell

Mitosis is a process of cell division which results in the production of two
daughter cells from a single parent cell. The daughter cells are identical to
one another and to the original parent cell.

In a typical animal cell, mitosis can be divided into four principals stages:

• Prophase: The chromatin, diffuse in interphase, condenses into

chromosomes. Each chromosome has duplicated and now consists of
two sister chromatids. At the end of prophase, the nuclear envelope
breaks down into vesicles.

• Metaphase: The chromosomes align at the equitorial plate and are

held in place by microtubules attached to the mitotic spindle and to
part of the centromere.

• Anaphase: The centromeres divide. Sister chromatids separate and

move toward the corresponding poles.

• Telophase: Daughter chromosomes arrive at the poles and the

microtubules disappear. The condensed chromatin expands and the
nuclear envelope reappears. The cytoplasm divides, the cell
membrane pinches inward ultimately producing two daughter cells
(phase: Cytokinesis).
 ENGAGE

IN THE WOMB
You are given the picture as shown below:

1. What do you observe?

2. How the foetus develop?

3. What is the main process that occurs during fetus

development?
 EMPOWER
STEPS
1. Mitosis is the type of cell division that produces new cell for growth and to
replace old cell that damaged or dead.
2. There are four main phases of mitosis:
- Prophase
- Metaphase
- Anaphase
- Telophase
3. Log on the web side and observe the animation to answer the question.
http://www.cellsalive.com/mitosis.htm

RESULT

Interphase
Prophase

Metaphase
Anaphase

Telophase
Cytokinesis
Questions

1. What is the role of mitosis in living organisms

2. How mutation occurs during mitosis?
3. Explain the example of mitosis application.

Answers:

1. Mitosis is important to maintain the diploid chromosome number in the cell. This is ensure
that chromosome number during sexual reproduction is remain from generation to the next
generation.

2. Mutation of the cell is due to mistake in replication of DNA as cell repair to divide, damage
to the DNA by radioactive and carcinogenic substances and destruction to the orderly
movement of chromosomes during cell division.

3. (i) Cloning in plant : tissue culture is the process of growing cell artificially in the
laboratory that produces genetically identical clone.
(ii) Cloning of animal : reproductive cloning that produces and entire animal that is
genetically identical to parent animal. While therapeutic cloning
apart of person (skin, heart, liver) are duplicated to produce a clone
in the treatment of disease
 ENHANCE

The diagram shows phases of mitosis of a plant cell in incorrect order

1 4

2
5

3 6

1. Based on the diagram, match the following figure with the correct
1
statements.
A Chromosomes completely arrive at the poles. _______________________
B Nuclear membrane disappear. _________________________
C. Paired centriol move to opposite ends of the cell ._____________________
D.Synthesis of new organelles, synthesis of protein and chromosome.
___________________
E. Sister chromatids line up at the spindle equator. ___________________
F. Chromatid condense and become visible under light microscope observation.
_____________________
G. Cell is ready for cytokinesis.________________________