The Neanderthals or Neandertals are an extinct species of human in
the genus Homo, possibly a subspecies of Homo sapiens. They are very closely related to modern humans, differing in DNA by only 0.3%, which however is twice that of the widest DNA gap found among contemporary humans. Remains left by Neanderthals include bones and stone tools, which are found from Western Europe to central Asia. The species is named after Neanderthal ("Neander Valley"), the location in Germany where it was first discovered. Neanderthals are generally classified by palaeontologists as the species Homo neanderthalensis, but a minority consider them to be a subspecies of Homo sapiens, (Homo sapiens neanderthalensis). The first humans with proto-Neanderthal traits are believed to have existed in Europe as early as 600,000350,000 years ago. The exact date of their extinction is disputed. Fossils found in the Vindija Cave in Croatia have been dated to between 33,000 and 32,000 years old, and Neanderthal artifacts from Gorham's Cave in Gibraltar are believed to be less than 30,000 years old, but a recent study has redated fossils at two Spanish sites as 45,000 years old, 10,000 years older than previously thought, and may cast doubt on recent datings of other sites. Cro-Magnon (early-modern-human) skeletal remains showing some "Neanderthal traits" have been found in Lagar Velho (Portugal) and dated to 24,500 years ago, suggesting that there may have been an extensive admixture of the Cro-Magnon and Neanderthal populations in that region. Several cultural assemblages have been linked to the Neanderthals in Europe. The earliest, the Mousterian stone tool culture, dates to about 300,000 years ago. Late Mousterian artifacts were found in Gorham's Cave on the south-facing coast of Gibraltar. Other tool cultures associated with the Neanderthals include the Chtelperronian, the Aurignacian, and the Gravettian; their tool assemblages appear to have developed gradually within their populations, rather than being introduced by new population groups arriving in the region. With an average cranial capacity of 1600cc, Neanderthal's cranial capacity is known to be notably larger than the 1400cc average for all races of modern humans, indicating that their brain size was at least as large, if not larger. In 2008, a group of scientists produced a study using three-dimensional computer-assisted reconstructions of Neanderthal infants based on fossils found in Russia and Syria. The study indicated that Neanderthal and modern human brains were the same size at birth, but by adulthood, the Neanderthal brain was larger than the modern human brain. They were much stronger than modern humans, having particularly strong arms and hands. Males stood 164168 cm (6566 in) and females about 152156 cm (6061 in) tall. Genetic evidence published in 2010 suggests that Neanderthals contributed to the DNA of anatomically modern humans, probably through interbreeding between 80,000 and 50,000 years ago with the population of anatomically modern humans who had recently migrated from Africa. According to the study, by the time that population began dispersing across Eurasia, Neanderthals genes constituted as much as 1 4% of its genome (roughly equivalent to having one Neanderthal great- great-great-grandparent). tzi the iceman, Europe's oldest preserved mummy, was found to possess an even higher percentage of Neanderthal ancestry. Recent findings suggest there may be even more Neanderthal genes in human, non-African genes than previously expected, at about 20% of the human genome instead. In December 2013, researchers reported evidence that Neanderthals practiced burial behavior and intentionally buried their dead. In addition, scientists reported, for the first time, the entire genome of a Neanderthal. The genome was extracted from the toe bone of a 130,000-year-old Neanderthal found in a Siberian cave.
Denisovan Denisovans or Denisova hominins are Paleolithic-era members of a species of Homo or subspecies of Homo sapiens. In March 2010, scientists announced the discovery of a finger bone fragment of a juvenile female who lived about 41,000 years ago, found in the remote Denisova Cave in the Altai Mountains in Siberia, a cave which has also been inhabited by Neanderthals and modern humans. Two teeth and a toe bone belonging to different members of the same population have since been reported. Analysis of the mitochondrial DNA (mtDNA) of the finger bone showed it to be genetically distinct from the mtDNAs of Neanderthals and modern humans.Subsequent study of the nuclear genome from this specimen suggests that this group shares a common origin with Neanderthals, that they ranged from Siberia to Southeast Asia, and that they lived among and interbred with the ancestors of some present-day modern humans, with about 3% to 5% of the DNA of Melanesians and Australian Aborigines deriving from Denisovans. A comparison with the genome of a Neanderthal from the same cave revealed significant local interbreeding, with local Neanderthal DNA representing 17% of the Denisovan genome, while evidence was also detected of interbreeding with an as yet unidentified ancient human lineage. Similar analysis of a toe bone discovered in 2011 is underway, while analysis of DNA from two teeth found in different layers than the finger bone revealed an unexpected degree of mtDNA divergence among Denisovans. In 2013, mitochondrial DNA from a 400,000 year old hominin femur bone from Spain, which had been seen as either Neanderthal or Homo heidelbergensis, was found to be closer to Denisovan mtDNA than to Neanderthal mtDNA.
Little is known of the precise anatomical features of the Denisovans since the only physical remains discovered thus far are the finger bone and two teeth from which genetic material has been gathered, and a toe bone. The single finger bone is unusually broad and robust, well outside the variation seen in modern people. Surprisingly, it belonged to a female, indicating the Denisovans were extremely robust, perhaps similar in build to the Neanderthals. The tooth that has been characterized shares no derived morphological features with Neanderthal or modern humans. An initial morphological characterization of the toe bone led to the suggestion that it may have belonged to a Neanderthal- Denisovan hybrid individual, although a critic suggested the morphology was inconclusive. This toe bone is currently undergoing DNA analysis by Pbo. Some older finds may or may not belong to the Denisovan line. These includes the skulls from Dali and Maba, and a number of more fragmentary remains from Asia. Asia is not well mapped with regard to human evolution, and the above finds may represent a group of "Asian Neanderthals". Homo sapiens Homo sapiens is the scientific name for the human species. Homo is the human genus, which also includes Neanderthals and many other extinct species of hominid; H. sapiens is the only surviving species of the genus Homo. Modern humans are the subspecies Homo sapiens sapiens, which differentiates them from what has been argued to be their direct ancestor, Homo sapiens idaltu. Scientific study of human evolution is concerned, primarily, with the development of the genus Homo, but usually involves studying other hominids and hominines as well, such as Australopithecus. "Modern humans" are defined as the Homo sapiens species, of which the only extant subspecies is known as Homo sapiens sapiens. Homo sapiens idaltu (roughly translated as "elder wise human"), the other known subspecies, is now extinct. Homo neanderthalensis, which became extinct 30,000 years ago, has sometimes been classified as a subspecies, "Homo sapiens neanderthalensis"; genetic studies now suggest that the functional DNA of modern humans and Neanderthals diverged 500,000 years ago. Similarly, the discovered specimens of the Homo rhodesiensis species have been classified by some as a subspecies, but this classification is not widely accepted. Anatomically modern humans first appear in the fossil record in Africa about 195,000 years ago, and studies of molecular biology give evidence that the approximate time of divergence from the common ancestor of all modern human populations was 200,000 years ago. The broad study of African genetic diversity found the San people to express the greatest genetic diversity among the 113 distinct populations sampled, making them one of 14 "ancestral population clusters". The research also located the origin of modern human migration in south-western Africa, near the coastal border of Namibia and Angola. The evolutionary history of primates can be traced back 65 million years (mya) Primates are one of the oldest of all surviving placental mammal groups. The oldest known primate-like mammal species (those of the genus Plesiadapis) come from North America, but inhabited Eurasia and Africa on a wide scale during the tropical conditions of the Paleocene and Eocene. Molecular evidence suggests that the last common ancestor between humans and the remaining great apes diverged 48 million years ago. The gorillas were the first group to split, then the chimpanzees (genus Pan) split off from the line leading to the humans. The functional portion of human DNA is approximately 98.4% identical to that of chimpanzees when comparing single nucleotide polymorphisms (see human evolutionary genetics). Therefore, the closest living relatives of humans are gorillas and chimpanzees, as they share a relatively recent common ancestor. Humans are probably most closely related to two chimpanzee species: the Common Chimpanzee and the Bonobo. Current estimates of suggested concurrence between functional human and chimpanzee DNA sequences range between 95% and 99%. Early estimates indicated that the human lineage may have diverged from that of chimpanzees about five million years ago, and from that of gorillas about eight million years ago. However, a hominid skull discovered in Chad in 2001, classified as Sahelanthropus tchadensis, is approximately seven million years old, and may be evidence of an earlier divergence. Human evolution is characterized by a number of important changes morphological, developmental, physiological, and behaviouralwhich have taken place since the split between the last common ancestor of humans and chimpanzees. The first major morphological change was the evolution of a bipedal locomotor adaptation from an arboreal or semi- arboreal one, with all its attendant adaptations (a valgus knee, low intermembral index (long legs relative to the arms), reduced upper-body strength). The human species developed a much larger brain than that of other primates typically 1,400 cm in modern humans, over twice the size of that of a chimpanzee or gorilla. The pattern of human postnatal brain growth differs from that of other apes (heterochrony), and allows for extended periods of social learning and language acquisition in juvenile humans. Physical anthropologists argue that the differences between the structure of human brains and those of other apes are even more significant than their differences in size. Other significant morphological changes included the evolution of a power and precision grip, a reduced masticatory system, a reduction of the canine tooth, and the descent of the larynx and hyoid bone, making speech possible. An important physiological change in humans was the evolution of hidden oestrus, or concealed ovulation, which may have coincided with the evolution of important behavioural changes, such as pair bonding. Another significant behavioural change was the development of material culture, with human-made objects becoming increasingly common and diversified over time. The relationship between all these changes is the subject of ongoing debate. The forces of natural selection have continued to operate on human populations, with evidence that certain regions of the genome display directional selection in the past 15,000 years. Red Deer Cave People The Red Deer Cave People were the most recent known prehistoric population that do not resemble modern humans. Fossils dated between 14,500 and 11,500 years old were found in Red Deer Cave and Longlin Cave in China. Having a mix of archaic and modern features, they are tentatively thought to be a separate species of humans that became extinct without contributing to the gene pool of modern humans. Evidence shows large deer were cooked in the Red Deer Cave, giving the people their name. In 1979, the partial skull of a cave dweller was found in Longlin Cave in the Guangxi Zhuang region of China. Further human remains were excavated from Maludong (Red Deer Cave) in Yunnan Province. Fossils of the Red Deer Cave dwellers were radiocarbon dated between 14,500 and 11,500 years of age, using charcoal found in the fossil deposits. During the period the Red Deer Cave people lived, all other prehistoric human species such as Neanderthals were thought to have died out. The Red Deer Cave humans would therefore be more recent than Homo floresiensis (dubbed "Hobbits") dated to 13,000 years ago. In spite of their relatively recent age, the fossils exhibit features of more primitive humans. The Red Deer Cave dwellers had the following distinctive features that differ from modern humans: flat face, broad nose, jutting jaw with no chin, large molars, prominent brows, thick skull bones, and moderate-size brain.
Although the physical features of the Red Deer Cave people suggest that they may be a previously undiscovered species of prehistoric human, the scientists who discovered them are reluctant to classify them as a new species. Chris Stringer of the Natural History Museum in London has suggested that they could be a result of mating between Denisovans and modern humans. Other scientists remain skeptical, suggesting that the unique features are within the variations expected for human populations. Attempts to extract DNA have been so far unsuccessful but are continuing. Only once this is done will it be possible to determine the relationship between this group and other modern humans. Homo floresiensis Homo floresiensis is an extinct species in the genus Homo. The remains of an individual that would have stood about 3 feet (0.91 m) in height were discovered in 2003 on the island of Flores in Indonesia. Partial skeletons of nine individuals have been recovered, including one complete cranium (skull). These remains have been the subject of intense research to determine whether they represent a species distinct from modern humans. This hominin is remarkable for its small body and brain and for its survival until relatively recent times (possibly as recently as 12,000 years ago). Recovered alongside the skeletal remains were stone tools from archaeological horizons ranging from 94,000 to 13,000 years ago. Some scholars suggest that the historical H. floresiensis may be connected by folk memory to ebu gogo myths prevalent on the isle of Flores. The discoverers (archaeologist Mike Morwood and colleagues) proposed that a variety of features, both primitive and derived, identify these individuals as belonging to a new species, H. floresiensis, within the taxonomic tribe of Hominini. Hominini currently comprises the extant species Homo sapiens (the only living member of the genus Homo), bonobo (genus Pan), and chimpanzee (genus Pan); their ancestors; and the extinct lineages of their common ancestor. The discoverers also proposed that H. floresiensis lived contemporaneously with modern humans on Flores. Doubts that the remains constitute a new species were soon voiced by the Indonesian anthropologist Teuku Jacob, who suggested that the skull of LB1 was a microcephalic modern human. Two studies by paleoneurologist Dean Falk and her colleagues (2005, 2007) rejected this possibility. Falk et al. (2005) has been rejected by Martin et al. (2006) and Jacob et al. (2006), but defended by Morwood (2005) and Argue, Donlon et al. (2006). Two orthopedic researches published in 2007 reported evidence to support species status for H. floresiensis. A study of three tokens of carpal (wrist) bones concluded there were similarities to the carpal bones of a chimpanzee or an early hominin such as Australopithecus and also differences from the bones of modern humans. A study of the bones and joints of the arm, shoulder, and lower limbs also concluded that H. floresiensis was more similar to early humans and apes than modern humans. In 2009, the publication of a cladistic analysis and a study of comparative body measurements provided further support for the hypothesis that H. floresiensis and Homo sapiens are separate species. Critics of the claim for species status continue to believe that these individuals are Homo sapiens possessing pathologies of anatomy and physiology. A second hypothesis in this category is that the individuals were born without a functioning thyroid, resulting in a type of endemic cretinism (myxoedematous, ME).
Analysis of Denisovan from different websources And so it begins. For years, evolutionary biologists have predicted that new human species would start popping up in Asia as we begin to look closely at fossilised bones found there. A new analysis of bones from south-west China suggests there's truth to the forecast. The distinctive skull (pictured, right) was unearthed in 1979 in Longlin cave, Guangxi Province, but has only now been fully analysed. It has thick bones, prominent brow ridges, a short flat face and lacks a typically human chin. "In short, it is anatomically unique among all members of the human evolutionary tree," says Darren Curnoe at the University of New South Wales in Sydney, Australia. The skull, he says, presents an unusual mosaic of primitive features like those seen in our ancestors hundreds of thousands of years ago, with some modern traits similar to living people. What's more, Curnoe and Ji Xueping of Yunnan University, China, have found more evidence of the new hominin at a second site Malu cave in Yunnan Province. Curnoe has dubbed the new group the Red Deer Cave people because of their penchant for venison. "There is evidence that they cooked large deer in Malu cave," he says. Exactly where the Red Deer Cave people belong in our family tree is unclear. Curnoe says they could be related to some of the earliest members of our species (Homo sapiens), which evolved in Africa around 200,000 years ago and then spread across Asia to reach China. He prefers the idea that they represent a new evolutionary line that evolved in East Asia in parallel with our species, just as Neanderthals did primarily because they look very different to early African members of our species. There are other possible interpretations. Chris Stringer at the Natural History Museum in London, says their distinctive primitive features might suggest they are related to the enigmatic Denisovan people, known from a 30,000 to 50,000-year-old finger bone and tooth found in a Siberian cave. We know that the Denisovans were living in East Asia, and from a DNA analysis, that they mated with our direct ancestors. The Red Deer Cave people, says Stringer, could even be the product of that mating. Although we still do not know exactly where they came from, we do know that the Red Deer Cave people survived until relatively recently. Some of the newly described fossils are just 11,500 years old, suggesting that unlike Neanderthals they made it through the height of the last ice age. They might not have been the only ancient humans to survive so late, says Michael Petraglia at the University of Oxford. We already know of human skeletons with unusual archaic features in south Asia and India that are just 8000 years old. The next step is to analyse DNA extracted from the Red Deer Cave bones, which will tell us more about their owner's evolutionary history whether they mated with any other hominins, for instance, and if they are truly a new species that evolved entirely in East Asia, as Curnoe believes, or are off-shoots of the Denisovan people. Curnoe says an initial attempt to extract good DNA from the fossils failed. "We are doing more work now involving three of the world's major ancient DNA laboratories," he says. "We'll just have to wait and see if we're successful." Source: http://www.newscientist.com/article/dn21586#.UvwlSRXFKM8 A mysterious extinct branch of the human family tree that once interbred with ours apparently lived in a vast range from Siberia to Southeast Asia, mating with just as widely spread a group of modern humans, scientists find. This new research also demonstrates that contrary to the findings of the largest previous genetic studies, modern humans apparently settled Asia in multiple waves of migration, investigators added. These lost relatives, known as the Denisovans, were discovered from at least 30,000-year-old bones and teeth unearthed in the Siberian Denisova cave in 2008. Analysis of DNA taken from these fossils suggested they shared a common origin with Neanderthals, but were nearly as genetically distinct from Neanderthals as Neanderthals were from living people. Source: http://www.livescience.com/16171-denisovans-humans- widespread-sex-asia.html
Conclusion A detailed comparison of the Denisovan, Neanderthal, and human genomes has revealed evidence for a complex web of interbreeding among the lineages. Through such interbreeding, 17% of the Denisova genome represents DNA from the local Neanderthal population, while evidence was also found of a contribution to the nuclear genome from an ancient hominin lineage yet to be identified, perhaps the source of the anomalously ancient mtDNA. There is evidence of a minimum 0.5% Neanderthal gene flow into the Denisovans. The Denisovan genome shared more derived alleles with the Altai Neanderthal genome from Siberia than with the Vindija Neanderthal genome from Croatia and the Mezmaiskaya Neanderthal genome from the Caucasus, suggesting that the gene flow came from a population that was more closely related to the Altai Neanderthal. It has also been observed that the Denisovan genome comprises a component derived from an unknown hominin that diverged long before the modern human/Neanderthal/Denisovan separated, suggesting a possible gene flow from said unknown hominin to Denisovans or a population sub- structure.