Question 1

Carbohydrate is stored in the Body principally as

A
Glucose
B
Maltose
C
Sucrose
D
Glycogen
E
Glycosaminoglycons
Question 2
A drug with half life (t1/2) 3hrs, and volume of distribution (Vd) 100ml/kg; Find total body
renal clearance, if patient wt is 70 kg.
A
102.4 L/kg
B
1.6 L/kg
C
7 L/kg
D
21 L/kg
E
29 L/kg
Question 3
Which of the following enzymes catalyzes the formation of uric acid from Purines?
A
Urease
B
Uricase
C
Xanthine oxidase
D
Aspartate transcarbamylase
E
Carbamyl Phosphate
Question 4
Prostaglandins are made within cells
A
On an RNA template
B
On rough endoplasmic reticulum
C
From methionine
D
From progesterone
E
From polyunsaturated fatty Acids
Question 5
A drug is said to reach study state when 5 half-lives have elapsed. In the case of warfarin
(a blood thinner), however, the steady state is dependent not upon the drugs half- life, but
upon the half-life of the clotting factors it inhibits. The clotting factors inhibited by
warfarin have the following half-lives: >Factor II 50hours.>Factor VII 6 hours. >Factor
IX 24 hours >Factor X 36 hours. >>Based on This information, how long will it take a
patient to reach maximal anticoagulation?
A
5 days
B
10 days
C
15 days
D
20 days
E
48 hours
Question 6
Vitamin k is necessary for
A
Ossification Osteoid
B
Formation of fibrinogen (factor I)
C
Formation of prothrombin (factor II)
D
Maturation of magacaryocytes to platelets
E
Maturation of collagen from tropocollagen
Question 7
The PRIMARY effect of calcitinin is to
A
Increase bone reabsorption
B
Inhibit bone reabsorption
C
Increase calcium absorption from intestine
D
Decrease calcium absorption from intestine
E
\(\displaystyle{A and C}\)
Question 8
How many gram Mg present in every 350ml dose >MgCO3 15gm, >Citric Acid
27.4gm, >Syrup 60ml,>H2O qs 350 ml, (Mg= 24.3, CO3= 60)(MgCO3 = 84.3)
A
4.3 g
B
8.7 g
C
87 g
D
19 g
E
21 g
Question 9
Which of the following enteric microorganisms is NOT typically found in the normal
human intestinal flora?
A
Escherichia Coli
B
Salmonella typhi
C
Proteus vulgaris
D
Bacteroides fragilis
E
Pseudomonas aeruginosa
Question 10
Cancer patients want to give him a TPN 250ml I.V. 4 times daily for 5 days. The bottle has
500ml size. The number of bottles used was:
A
5
B
10
C
20
D
15
E
7.5
Question 11
The two genera MOST frequently Associated with bacterial cystitis are
A
Salmonella and shigella
B
Hemophilus influenza
C
Psedomonas
D
E.coli
E
Gonorrhea
Question 12
In which of the following parts of the circulatory System is Blood pressure The LOWEST?
A
Aorta
B
Veins
C
Arterioles
D
Capillaries
E
Large arteries
Question 13
Which of the following Conditions Are NOT mediated by antibody?
A
Hay fever
B
Anaphylaxis
C
Serum sickness
D
Contact dermatitis
E
Autoimmune hemolytic disease
Question 14
Gout is an example of disturbance in the metabolism of
A
Calcium
B
Purines
C
Cholesterol
D
Carbohydrates
E
None
Question 15
Which of the following hormones exerts the LEAST Effect on Calcium metabolism of bone
tissue?
A
Androgen
B
Estrogen
C
Norepinephrine
D
Thyroid hormone
E
Parathyroid hormone
Question 16
Hyperplasia is a condition In which there is
A
An increase in the size of A part , organ or cell
B
An decrease in the size of A part , organ or cell
C
An increase in number of Individual tissue elements or cells in a given organ
D
A congenital defective formation in which there is Incomplete development Of an
organ or part
E
The production of one type of adult tissue by cells which normally produce tissue
of another Type
Question 17
The relative refractory Period of a nerve Corresponds to
A
Sodium permeability changes
B
Decreased potassium permeability
C
Increased potassium permeability
D
Threshold potential That is farther from zero
E
None of the above
Question 18
Which of the following Cells are associated with liberation of histamine?
A
Lymphocytes
B
Cytotoxic T cells
C
Plasma cells
D
Mast cells
E
T4 cells
Question 19
Carbon monoxide DECREASES the Amount of
A
Bicarbonate in the blood plasma
B
Carbonic anhydrase available in the lungs
C
Oxygen that can be transported by Hemoglobin
D
Alveolar surface available for gaseous exchange
E
Carbon dioxide that can be transported by the blood
Question 20
Thyroid secretion is stimulated
A
Hypoxia
B
Propylthiouracil
C
Exogenous thyroid hormone
D
High serum iodide concentration
E
Prolonged exposure to a cold environment
Question 21
8meq of KCL was given 3 times daily to patient experiencing hypokalemia. The umber mg
taking per day is (M.wt of K=39, Cl=35.5)
A
596mg
B
1788mg
C
1192mg
D
D) None of the above
Question 22
What is the final percentage of ZnO ointment made by mixing ZnO ointment of the
following strengths : 200 gram of 10% + 50 gram of 20 % + 100gram of 5%
A
10%
B
20%
C
5%
D
100%
E
50%
Question 23
What is a rate of constant of heparin in first order kinetic if 50 units/mL of heparin
remains in solution after 10 days? [Initial concentration of heparin was 5000 units/mL]
A
2.1 day-1
B
0.5 day-1
C
0.46 day-1
D
1.23 day-
Question 24
Which of the following has been shown to have relationship with carcinoma of cervix?
A
Papilloma virus
B
Vericella zoster virus
C
Herpes virus type I
D
Herpes virus type II
E
None of the above
Question 25
What is a rate of constant of the drug having initial concentration of drug 1000mg/cc and
100mg/cc after 90 minutes?
A
0.025 min-1
B
0.5 min-1
C
2.2 min-1
D
3.2 min-1
Question 26
Etiology concerned primarily with :
A
Symptomology
B
Racial origin
C
Causation
D
Language facility
Question 27
Organisms belonging to Which of the following genera Can tolerate the Lowest PH?
A
Veillonella
B
Bacteroids
C
Streptococcus
D
Lactobacillus
E
Stephyllococcus
Question 28
Vitamin A functions to:
A
Prevent pallagra
B
Promote absorption of calcium
C
Promote differentiation of epithelial cells
D
Maintain the integrity of connective tissue
E
Maintain skin hue
Question 29
Which of the following clotting factor is NOT inhibited by warfarin?
A
2
B
7
C
9
D
10
E
12
Question 30
Shingles is caused by ________ virus?
A
Rubella
B
Herpes zoster
C
Herpes simplex
D
New castle disease
E
Papilloma
Question 31
The presence of glucose In the urine proves That the patient has
A
Diabetes mellitus
B
Negative Nitrogen balance
C
Exceeded his renal threshold for glucose
D
Excessive damage to a gromerulus of the kidney
E
None of the above
Question 32
Which of the following is NOT Characteristics of plasmids?
A
Confer conjuGal fertility
B
Carry genetic information
C
Exist as circular RNA Molecules
D
Exist as extrachrosomal Elements in bacteria
E
None of the above
Question 33
The class of hemoglobin responsible for atopic Allergy is
A
IgA
B
IgD
C
IgE
D
IgG
E
IgM
Question 34
A nurse in a surgical ward is transfusing 0.5ml/min of gentamycin sulfate. The dropping of
the solution id 5ml/minute. The patient is receiving an amount of drug per hour
A
150mg/hr
B
300mg/hr
C
2.5mg/hr
D
5mg/hr
E
6mg/hr
Question 35
A script of prednisone 100mg twice a day. The physician would like to taper the prednisone
by approximately 20% daily until the patient is off the medication. How many prednisone
10 mg tabs should be dispensed?
A
160
B
79
C
20
D
200
E
100
Question 36
The most common cause for megaloblastic anemia is
A
Gastric bleeding
B
Lack of dietary iron
C
Lack of dietary folic acid
D
Lack of dietary pyridoxine
E
Lack of absorption of bit B12
Question 37
Which of the following substances are considered to be chemical mediators for vascular
dilatation At the initial phase of acute inflammation? >> I. Seratonin. >> II. Histamine. >>
III. Bradykinin
A
I only
B
III only
C
I and II only
D
II and III only
E
All of the above
Question 38
Alpha cells in the islands of Langerhans Are the source of
A
Insulin
B
Glucagon
C
Glycogen
D
Secretin
E
Thiamine
Question 39
Which of the Following Cell types Is associated with antibody formation?
A
Basophil
B
Monocyte
C
Eosinophil
D
Neutrophil
E
Plasmacell
Question 40
A was admitted to ER And was given kcl injections As 60 mg every 12 hours For 3 days.
The patient was taking 3ml in each injection. The label of the injection is 60 mg/3ml . The
number of injections the patient received is :
A
3
B
4
C
5
D
6
E
8
Question 41
Nitroglycerin 0.4mg #100; iSL pm CP, MR q5min x 2, your label directions?
A
Dissolve under the tongue one tablet as needed for chest pain. May repeat every 5
minutes if pain persists, to a maximum of 2 additional doses
B
Take nitroglycerin 0.4mg SL as needed and may repeat every 5 minutes if pain
persists, to maximum of 2 doses.
C
Take nitroglycerin 0.4mg SL as needed and may repeat every 5 minutes if pain
persist, to maximum of 2 doses
D
Give nitroglycerin 0.4mg SL as needed and may repeat every 5 minutes if pain
persist, to maximum of 2 doses
Question 42
Agents that would be suitable for a patient who has a known allergy to acetyl salisylic acid
(ASA) Include which of the following?
A
Diclofenac
B
Propoxyphene
C
Ibuprofen
D
Indomethacin
E
Naproxen
Question 43
Myxedema is an endocrine disturbance resulting from
A
Secondary hyperthyroidism in children
B
Primary hyperthyroidism in adults
C
Hyperpituitarism in adults
D
Hypothyroidism in children
E
hypothyroidism in adults
Question 44
Rheumatic fever is a Disease which
A
Can result from a transient Bacteremia by Viridans streptococci
B
Is preceded by a group of A streptococcal infection of the heart
C
Develops as a sequela to group a streptococcal
D
Affects the glomeruli of the kidney
E
All of the above
Question 45
Find Cp (plasma concentration.) for a drug, if the dose is 50 mg iv, and wt=140lb and
volume of distribution (Vd) = 1.61 L/kg
A
102.4L/hr
B
161 L/hr
C
261 L/hr
D
140 L/hr
E
50 L/hr
Question 46
How many 4mg tabs are needed? Weight of the child = 44lb Rx: >Ondensetron HCL -
0.15mg/kg/tsp. >Cherry Syrup qs 60ml
A
4 tabs
B
6 tabs
C
9 tabs
D
12 tabs
E
10 tabs
Question 47
An insurance company puts a plan to cover the lowest price medication and also covers the
10% higher than the lowest price. You have the following data. Based on daily dose. What
medications should be covered by this company?
A
25mg/day (25mg/$ 2.20)
B
100mg QID (50mg/$0.30)
C
40mg/BID (20mg/$0.45)
D
12mg/BID (12mg/$0.91)
Question 48
Which of the following is NOT a function of liver
A
Detoxification
B
Gluconeogenesis
C
Formation of plasma protein
D
Secretion of digestive enzymes
E
Regulation of blood sugar level
Question 49
The km value of an enzyme Is numerically Equal to
A
Half the Maximum velocity expressed in moles/litre
B
Velocity of a reaction divided by substrate concentration
C
Substrate concentration In moles /litre necessary to achieve Half the maximum
velocity Of a reaction
D
Maximum velocity divided by half the substrate concentration in moles necessary
to Achieve maximum velocity
E
Substrate concentration divided by Velocity of a reaction
Question 50
The physiological active form of vitamin D produced in the kidney is
A
1,25-dihydroxycholecalciferol
B
25,hydroxycholecalciferol
C
7-dehydrocholesterol
D
Cholescalciferol
E
Ergostero