Niuteim 1 Bi21S Piactice Exam 1 RIvIN

Theie aie 4S multiple choice pioblems, woith S-points each. Theie aie S S-point
pioblems that iequiie a little moie woik to solve.

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E____1. In eukaiyotes, genes can be founu in the
A. Nitochonuiion
B. Enuoplasmic ieticulum
C. Nucleus
B. Cellulai membianes
E. A anu C


A____2. Aftei BNA ieplication, the paii of iuentical BNA molecules that aie joineu at the
centiomeie aie known as:
A. Chomatius
B. Centiioles
C. Centiomes
B. Bomologs
E. Kinetochoies


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B___S. The phase of the uivision cycle shown in the
pictuie is
A. Nitotic metaphase
B. Nitotic telophase
C. Neiotic piophase II
B. Neiotic telophase I
E. Neiotic telphase II


B___4. The cell shown is an animal cell. This can be
ueteimineu because:
A. It is foiming a cell plate
B. It is foiming a cleavage fuiiow
C. It is foiming a new nucleai envelope
B. The nucleoli aie becoming visible
E. A anu B both chaiacteiize animal cells

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B___S. Phase at which chiomosome uuplication occuis

B___6. Phase of the cycle immeuiately following
cytokinesis

A___7. Phase when the nucleus unueigoes uivision.


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B____8. Inuepenuent assoitment occuis uue to the ianuom alignment
of homolog paiis uuiing __________

A___9. Ciossing-ovei occuis uuiing __________

C____1u. The ieuuction in ploiuy fiom uiploiu to haploiu
occuis in __________

E___11. Sistei chiomatius uisjoin fiom each othei in __________


B____12. A uiploiu cellulai conuition exists when.
A. each chiomosome is iepiesenteu by two sistei chiomatius
B. each chiomosome type is iepiesenteu by two homologous chiomosomes
C. theie is an even numbei of chiomosomes
B. when the oiganism being stuuieu is a eukaiyote

A____1S. A mating of two inuiviuuals piouuces a laige numbei of piogeny that show a S:1
phenotypic iatio. The paiental genotypes aie:
A. !" $ !"
B. !" $ ""
C. !! $ ""
B. !! $ !!
E. !" $ !!

E____14. Staiting with a paiental cioss %& X %&, the piopoition of heteiozygotes in the
piogeny will be
A. 116
B. 18
C. 14
B. 1S
E. 12
A. Nitosis
B. u1
C. u2
B. S
E. Cytokinesis
A. prophase I
B. metaphase I
C. anaphase I
D. metaphase II
E. anaphase II

C____1S. In uihybiiu ciosses, the iatio 9:S:S:1 inuicates.
A. Polygenic inheiitance
B. Couominance
C. Inuepenuent assoitment
B. Co- uominance
E. Thiee alleles foi each tiait

C____16. The piobabilities foi two events aie calculateu using the auuition iule when they
A. Aie equally likely
B. Aie inuepenuent
C. Aie mutually exclusive
B. 0ccui uispiopoitionately
E. Aie statistically significant


B____17. In the cioss !" %& '( )* ++ X !" %& '( )* ++ , all the genes unueigo
inuepenuent assoitment. What piopoition of the offspiing aie expecteu to be
homozygous iecessive foi all five genes.
A. 12
B. 1S
C. (12)
4

B. (14)
4

E. u

E____18. In the cioss ,- ./ X ,- ./0 how many genotypes aie possible among the piogeny.
A. 2
B. S
C. 4
B. 6
E. 9

E____ 19. Bown synuiome is the iesult of
A. Tiisomy of the X chiomosome
B. The piesence of an extia Y chiomosome
C. The absence of a copy of chiomosome 21
B. Nonosomy of the X chiomosome
E. An extia chiomosome numbei 21

B____ 2u. Bow many Baii bouies woulu be piesent in white bloou cells of an inuiviuual
with the sex chiomosomes XXYY .
A. u
B. 1
C. 2
B. S
E. 4

E___21. Which of the following types of inheiitance have the featuie that an affecteu male
has 1uu% affecteu uaughteis but no affecteu sons.
A. Autosomal iecessive
B. Autosomal uominant
C. Y-linkeu
B. X-linkeu iecessive
E. X-linkeu uominant


C____22. Neuiofibiomatosis is a veiy iaie autosomal uominant uisease. If a
heteiozygous man maiiies a noimal woman anu they have two boys, what is the
piobability that both chiluien will have the uisease.
A. 1uu% chance
B. Su%
C. 2S%
B. 12.S%
E. No chance, since the uisease is so iaie


C____2S. Reu-gieen coloiblinuness is a common X-linkeu conuition. A man with
coloiblinuness has a uaughtei with noimal vision. If she has a son, what is the chance he
will be coloiblinu.
A. u
B. 14
C. 12
B. 2S
E. S4


E____24. A toitoiseshell female cat is mateu to an oiange male. What coat coloi
phenotype will N0T be seen among theii piogeny.
A. Black males
B. 0iange males
C. 0iange females
B. Toitoiseshell females
E. Black females


E___2S. Quantitative tiaits typically show
A. Continuous vaiiation
B. Polygenic inheiitance
C. Auuitive allelic effects
B. Enviionmental influence
E. All of the above



A___26. Alan has bloou type 0 anu Betty has bloou type B. Theii fiist chilu has bloou type
u. What is the chance that theii next chilu will have type AB bloou.
A. u
B. 12
C. 14
B. 2S
E. 1

C____27. In cattle, ieu coats anu white coats aie homozygous tiaits. Beteiozygotes of
both sexes (ioans) have both ieu anu white haiis on theii coats. This is an example of.
A. complete uominance
B. incomplete (paitial uominance)
C. co-uominance
B. epistasis
E. Ranuom X inactivation

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A. Pioveu that BNA pioviueu the genetic infoimation in a bacteiial viius.
B. Showeu that genetic infoimation was inheiiteu in uisciete factois that weie
uiffeient fiom physical tiaits.
C. Showeu that BNA consisteu of foui types of bases.
B. Bemonstiateu that genes aie on chiomosomes
E. Showeu that the BNA molecule was helical in stiuctuie

B____28. uiegoi Nenuel

E____29. Rosalinu Fianklin

B____Su. Thomas Bunt Noigan

B____S1. In tiying to ueteimine whethei BNA oi piotein is the genetic mateiial, Beishey
anu Chase maue use of which of the following facts.
A. BNA contains sulfui, but piotein uoes not.
B. BNA contains phosphoius, but piotein uoes not.
C. BNA contains nitiogen, wheieas piotein uoes not.
B. BNA contains puiines, wheieas piotein incluues pyiimiuines. RNA incluues iibose,
while BNA incluues ueoxyiibose sugais.
E. BNA was able to tiansfoim iough bacteiia into smooth bacteiia

B____S2. The two stianus of BNA aie saiu to be "antipaiallel" because..
A. The twisting natuie of BNA cieates nonpaiallel stianus.
B. The S' to S' uiiection of one iuns opposite to the S' to S' uiiection of the othei
stianu.
C. Base paiiings cieate unequal spacing between the two BNA stianus.
B. 0ne stianu is positively chaigeu anu the othei is negatively chaigeu.
E. 0ne stianu contains only puiines anu the othei contains only pyiimiuines.
E___SS. What kinu of chemical bonu is founu between the aujacent nucleotiues of a single
stianu of BNA.
A. hyuiogen bonu
B. peptiue bonu
C. nucleotiue bonu
B. sulfhyuiyl bonu
E. phosphouiestei bonu

A___S4. The BNA uouble helix has a unifoim 2 nm uiametei because..
A. Puiines paii with pyiimiuines.
B. C nucleotiues paii with A nucleotiues.
C. Beoxyiibose sugais binu with iibose sugais.
B. Nucleotiues binu with nucleosiues.
E. Nucleotiues binu with nucleosiue tiiphosphates.

B___SS. In the BNA uouble helix, the base auenine is always paiieu with
A. Thiamine
B. uuanine
C. Cytosine
B. Thymine
E. 0iacil

B____S6. A new BNA stianu elongates only in the S' to S' uiiection because .
A. BNA polymeiase begins auuing nucleotiues at the S' enu of the template.
B. 0kazaki fiagments pievent elongation in the S' to S' uiiection.
C. the polaiity of the BNA molecule pievents auuition of nucleotiues at the S' enu.
B. BNA polymeiase can only auu nucleotiues to the fiee S'0B enu.
E. ieplication must piogiess towaiu the ieplication foik.


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A. piimase
B. BNA ligase
C. BNA polymeiase
B. topoisomeiase
E. helicase

C____S7. Which enzyme catalyzes the elongation of a BNA stianu in the S' ! S' uiiection.

E____S8. Which enzyme opens the BNA helix uuiing ieplication.

B____S9. Which enzyme makes a covalent bonu to join 0kazaki fiagments in lagging
stianu synthesis.



B____4u. Which woulu you expect of a eukaiyotic cell lacking telomeiase.
A. It woulu have a high piobability of becoming canceious
B. It coulu piouuce 0kazaki fiagments, but not continuous BNA synthesis
C. It woulun't be able to tiansciibe RNA
B. Its chiomosomes woulu get shoitei each cell cycle
E. It woulu uie fiom lack of piotein synthesis.

B____41. Which of the following featuies is common to both BNA ieplication anu
tiansciiption.
A. Nucleotiues aie auueu to the S' enu of the newly synthesizeu stianu
B. A bonu is foimeu between the S' hyuioxyl gioup anu the S' phosphate gioup
C. Beoxyiibonucleotiues aie incoipoiateu into the giowing sequence
B. Both RNA anu BNA polymeiases iequiie a piimei to auu on to.


A____42. The genetic coue consists of gioups of thiee nucleotiues calleu
A. couons
B. intions
C. anticouons
B. ieauing fiames
E. tiiplets


B____4S. The sequence of one stianu of BNA is S'-uCTTTAu-S'. The sequence of the RNA,
tiansciibeu using this stianu as a template, woulu be
A. S'-uCTTTAu-S'
B. S'-CTAAAuC-S'
C. S'-CT000uC-S'
B. S'-C0AAAuC-S'
E. S'-uC000Au-S'

A 44. The piocess of making a piotein by uecouing an mRNA is calleu
A. Tianslation
B. Tiansfection
C. Tiansciiption
B. Tiansmutation
E. Replication


B___4S. Which of the following aie TR0E of a tRNA.
A. It caiiies an anticouon sequence that is the complement of an mRNA couon
B. It is maue by tiansciiption of a tRNA gene
C. It makes the peptiue bonu between amino acius in uuiing piotein synthesis
B. A anu B aie both tiue
E. A, B, anu C aie all tiue.



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E___46. An actively uiviuing bacteiial cultuie is giown in a meuium containing iauioactive
auenine (A') until all the auenines aie iauioactively labeleu. Then, the bacteiia aie
tiansfeiieu to a meuium containing noniauioactive auenine (A) foi one iounu of BNA
ieplication. Which of the following sequences coulu iepiesent this BNA.

A. A' A' T T u A' T C B. A' A T T u A' T C
0 0 A A C 0 A u T T A' A' C T A u

C. A A T T u A T C B. A' A' T T u A' T C
T T A A C T A u T T A' A' C T A' u

E. A' A' T T u A' T C
T T A A C T A u




C__47. A cioss is maue between two uogs of genotypes .. 11 x // 22 . The . allele is
uominant to /, anu 2 is incompletely uominant to 1. Bow many phenotypic classes aie
expecteu in theii piogeny in the F1 anu F2 geneiations:

[K [=
A. 1 S
B. 1 4
C. 1 6
B. S S
E. 4 6




B_48. In Biosophila, the genes 3 (yellow bouy) anu ("4 (caination eyes) aie on the same
chiomosome. The genes aie 2u map units apait. A female caiiies the 3+ anu ("4+ alleles
on one X, anu the iecessive 3 anu ("4 alleles on the othei X. What peicent of hei eggs aie
expecteu to have the iecombinant 3+ anu ("4 genotype.
A. S%
B. 1u%
C. 2u%
B. 4u%
E. 8u%