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1 .
| . 2000 2 2 2 8 o 7 9 .
2 .
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201 20 2 1 8 o 57 59 .
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201 28 2 5 8o 19 145 .
4 . H . 7 . o
2008 o 298 299 .
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9 6 5 2014 4 55 7 |ournal of 1radiiional Chinc-c Hcdicinc 2014 \ol . 55 ^o . 7
7 .
. 2 20108 | .
2010 8 2 8 o 195 208 .
8 . /
| . 2011 2 2 8 8 o 876877 .
9 .
| . 2008 24 2 2 8 o 402407 .
10 Kara- H Hillcnkamp I . La-cr dc-orpiion ionizaiion of
proicin- wiih molccular ma--c- cxcccding 10 000 dalion-
| . Anal Chcm 1988 60 2 20 8 o 2299 201 .
11 Icnn |B Hann H Hcng CK ci al . Llcciro-pray ionizaiion
for ma-- -pcciromciry of largc hiomolcculc- | . Scicncc
1989 246 2 4926 8 o 64 71 .
12 . IgC .IgA .IgH .C .C4 .CBP
| . 2008 19
2 8 o 124125 .
1 Iihrinogcn Siudic- Collahoraiion Kapiogc S Vhiic IB ci
al . A--ociaiion- of pla-ma fihrinogcn lcvcl- wiih c-iah
li-hcd cardiova-cular di-ca-c ri-k facior- inflammaiory
markcr- and oihcr characicri-iic- o individual pariicipani
mcia analy-i- of 154 211 aduli- in 1 pro-pcciivc -iudic- o
ihc fihrinogcn -iudic- collahoraiion | . Am | Lpidcmiol
2007 166 2 8 8 o 867 879 .
14 Sanchcz Lazaro I| Almcnar L Bcganon L ci al . Inflam
maiory markcr- in -iahlc hcari failurc and ihcir rclaiion
-hip wiih funciional cla-- | . Ini | Cardiol 2007 129
2 8 o 88 9 .
15 hang X Hc HA Chcng L ci al . |oini cffcci- of aniihody
io hcai -hock proicin 60 hypcricn-ion and diahcic- on
ri-k of coronary hcari di-ca-c in Chinc-c | . Clin Chcm
2008 54 2 6 8 o 1046 1052 .
16 hu | uyyumi AA Boii I ci al . Aniihodic- io human
hcari -hock proicin 60 arc a--ociaicd wiih ihc prc-cncc
and -cvcriiy of coronary aricry di-ca-c o cvidcncc for an au
ioimmunc componcni of aihcrogcn-i- | . Ciruclaiion
2001 10 2 8 8 o1071 1075 .
17 Huiiiincn 1 Lcinoncn H 1cnkancn L ci al . Auioimmu
niiy io human hcai -hock proicin 60 Chlamydia pncumon
iac infcciion and inflammaiion in prcdiciing coronary ri-k
| . Aricrio-clcr 1hromh \a-c Biol 2002 22 2 8o 41
47 .
18 hu | Kaia B| uyyumi AA ci al . A--ociaiion of -crum
aniihodic- io hcai -hock proicin 65 wiih coronary calcifi
caiion lcvcl- o -uggc-iion of paihogcn iriggcrcd auioimmu
niiy in carly aihcro-clcro-i- | . Circulaiion 2004 109
2 1 8 o6 41 .
Specific Serum Markers f Heart Failure Patients With Ischemic Cardimypathy and Qi-Deficiency Bld-
Stasis Pattern
YANG Yalig
1
CAO Xuebi
1
XE Yaa
1
WANG Xiaghe
1
HE Jiacheg
2
ZHANG Gag
1
HU Yua
hui

L Juxia
4
2 1 . 252 Ho-piial of Chinc-c PLA Hchci Provincc 071000 m 2 . Shanghai Inivcr-iiy of 1radiiional Chinc-c Hcdicinc m . Cuang anmcn
Ho-piial China Acadcmy of Chinc-c Hcdical Scicncc-m 4 . Ccncral Ho-piial of Bcijing Hiliiary Bcgion 8
ABSTRACT Objective 1o rc-carch ihc -pccira of -crum pcpiidc- and -crum markcr- of hcari failurc paiicni- wiih
i-chcmic cardiomyopaihy and qi dcficicncy hlood -ia-i- paiicrn . Methds 1hc -crum -amplc- from 0 hcari failurc
paiicni- wiih i-chcmic cardiomyopaihy and qi dcficicncy hlood -ia-i- paiicrn 2 oh-crvaiion group 8 and 20 hcalihy pcr
-on- 2 normal conirol group 8 wcrc collccicd . 1hc -pccira of -crum pcpiidc- wa- ohiaincd hy mairix a--i-icd la-cr dc
-orpiion ionizaiion / iimc of flighi ma-- -pcciromciry 2 HALII 10I HS 8 . 1hc -pccira modcl of -crum pcpiidc- wa- c-
iahli-hcd wiih Clinproi iool-2 . 1 and -iaii-iical mcihod- . Results 1hcrc wcrc 47 diffcrcniially cxprc--cd proicin
pcak- in ihc oh-crvaiion group and normal conirol group . 1hc modcl wa- c-iahli-hcd wiih fivc pcak- ohiaincd from
-crccning ihc hc-i markcr- . 1hcrc wcrc low cxprc--ion- of 1866 . 17 Ia 7761 . 49 Ia 1848 . 81 Ia and 207 .
57 Ia in ihc oh-crvaiion group . 1hcrc wa- a high cxprc--ion of 2660 . 54 Ia in ihc oh-crvaiion group . 1hrcc kind- of
amino acid -cqucncc- -uch a- complcmcni C f fihrinogcn and hcai -hock proicin 60 wcrc ohiaincd hy -carching fivc
proicin pcak- in ihc polypcpiidc amino acid -cqucncc daiaha-c . Cnclusin 1hc -pccific markcr- of hcari failurc
paiicni- wiih i-chcmic cardiomyopaihy and qi dcficicncy hlood -ia-i- paiicrn arc complcmcni C f fihrinogcn and hcai
-hock proicin 60 .
Keywrds i-chcmic cardiomyopaihy m -pccira of -crum pcpiidc- m qi dcficicncy hlood -ia-i- paiicrn m hcari failurc m
ma-- -pcciromciry m -crum markcr
2 o 201 09 25 m o 201 12 2 8
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0 7 5 2014 4 55 7 |ournal of 1radiiional Chinc-c Hcdicinc 2014 \ol . 55 ^o . 7