STUDY GUIDE RT 244 (Notes from Bushongs text) pg pg !
Radiation Protection & Radiobiology Notes
"um#n B$o%og& "um#n Response To Ion$'$ng R#($#t$on Early Effects of Radiation: When response occurs within minutes or days after exposure. Late Effects of Radiation: When response is not observed for many months or years after exposure. Effects of fetal irradiation: Death, malformation, malignancy, diminished growth. )ompos$t$on of "um#n Bo(& )e%% Theor&* !" of the body is hydrogen and oxygen. #ydrogen: $%" &xygen: '!.(" )arbon: *%.(" +itrogen: '.," +o%e,u%#r )ompos$t$on Water: %" - . simple molecule. /rotein: *!" - . macromolecule. 0at: '" - . macromolecule. &ther: 1" T$ssues #n( -rg#ns* 23he most radiosensitive cells in the human body are Lymphocytes 4 5permatogonia. .un(#ment#% /r$n,$p%es of R#($o0$o%og& 1#2 of Bergon$e #n( Tr$0on(e#u *6 &lder cells are more radioresistant. '6 7ounger cells are more radiosensitive. #ow these principles apply to radiation safety: 3he fetus is more radiosensitive to radiation than a child or adult. B$o%og$, .#,tors 3ffe,t$ng R#($osens$t$4$t& .ge: #umans are most sensitive before birth. 8ender: 0emales are less radiosensitive than males. +o%e,u%#r #n( )e%%u%#r R#($o0$o%og& Irr#($#t$on of +#,romo%e,u%es* 2p.,!%6 0ollows a Linear, +on-threshold dose9response relationship. Radiation Effects on D+.: D+. is the most radiosensitive macromolecule. *6 )ell death '6 :alignant disease 16 8enetic damage R#($o%&s$s of 5#ter* ;ndirect Effect. :ost prevalent in humans. We are mostly water: %" Water STUDY GUIDE RT 244 (Notes from Bushongs text) pg 2 pg ! 2 3he brea<down of water by radiation is harmful. =rea<down products, called free radicals, cause D+. damage. D+. damage can cause somatic and genetic outcomes. D$re,t #n( In($re,t Effe,t Direct Effect: Radiation hits D+. causing cell damage. ;ndirect Effect: ' 5tep process 3he principle action of radiation on humans is the ;ndirect Effect. *6 Radiation brea<s down water molecules. '6 =rea< down products 2free radicals6 damage D+.. S$ng%e6T#rget7 S$ng%e6"$t +o(e% /oisson Distribution: . statistical law. ;f *%% rain drops fell on *%% s>uares, $1" will be wet, 1(" will be dry. E#r%& Effe,ts of R#($#t$on 3,ute R#($#t$on 1eth#%$t&* ?-ray beams are not large or intense enough to cause radiation lethality. Early Effects: 5ee a radiation response within a few days. 1o,#% T$ssue D#m#ge*Re>uires a higher dose to produce a response. Results in tissue atrophy. 5<in: Er&them#- a sunburn-li<e redness. 5ED !% 25<in Erythema Dose to affect !%" of pop.6 at $%% Rad. 8onads: &varies 4 3estes are very sensitive to radiation. /ermanent sterility at !%% Rad. 1#te Effe,ts of R#($#t$on 1o,#% T$ssue Effe,ts 5<in: #igh doses of radiation causes discolored and weathered appearance of s<in. )hromosomes: Damage to lymphocytes can produce both an early and a late response. )ataracts: 3he eye@s sensitivity is age dependent. ;ncrease in age, increases effects. )ataracts at *,%%% Rad 1$fe Sp#n Shorten$ng *% days per rad: 7ou can loose *% days of life for every rad received. Relative safety of occupation: Radiologic 3echnology is considered a safe occupation. R$s8 Est$m#tes Relative Ris<: &bserved cases A Expected cases. Estimate used when you don@t <now the original dose. Excess Ris<: &bserved cases - Expected cases. Estimate using the excess cases induced. .bsolute Ris<: Estimate using ' <nown dose levels. R#($#t$on In(u,e( +#%$gn#n,& STUDY GUIDE RT 244 (Notes from Bushongs text) pg 9 pg ! 9 Leu<emia: Linear, +on-threshold. ,-( year latent period. '% year Bat ris<B period. 3hyroid )ancer: Linear, +on-threshold dose9response relationship. =one )ancer: Radium watch-dial painters developed bone cancer. 5<in )ancer: 0ollows a threshold dose9response relationship. =reast )ancer: .tomic blast survivors who received *% Rads plus, exhibited a ris< factor of ,:*. Lung )ancer: Cranium miners show a ris< factor of :*. Liver )ancer: B3horotrastB contrast agent, caused liver cancer after *!-'% year latent period. Tot#% R$s8 of +#%$gn#n,& &verall .bsolute Ris< of :alignancy: 2p.,(6 .pproximately *% cases9*% $
persons9rad9year, '! years after exposure. R#($#t$on #n( /regn#n,& ;rradiation in Ctero: #igh dose may interrupt fertility. 0irst two wee<s: 3he first two wee<s of pregnancy may be the safest. . high dose may produce a spontaneous abortion. 3his is an all or none dose9response relationship. :aDor organ formation: 0rom the 'nd - *%th wee< of gestation. #igh rad dose will produce s<eletal, organ and )+5 abnormalities. 5ummary of effects "e#%th /h&s$,s )#r($n#% /r$n,$p%es of R#($#t$on /rote,t$on* 3ime, Distance and 5hielding. +$n$m$'e T$me* Eeep exposure time as short as possible. Exposure F exposure rate x time +#x$m$'e D$st#n,e* Cse the longest 5;D possible from the source. Doubling the distance drops the exposure by , times. 3echnologist should be as far from the source as practical. +#x$m$'e Sh$e%($ng* ;nsert shielding between the source and person. #alf Galue Layer of Lead 2at %<Gp6: .*Hmm Lead. 3enth Galue Layer of Lead 2at % <Gp6: .$,mm Lead. Dose 1$m$t (D1) Definition: Ensures that radiation wor<ers have the same ris< as those in safe industries. 3here is no patient DL. 5ummary of DL: 5ummary of +)R/ Dose Limit Recommendations. 25ee the last page of this guide.6 3nnu#% D1 $s st$%% : rem;&r (:< mS4;&r) )umu%#t$4e D1 $s Rem x #ge (< mS4 x #ge) E(u,#t$on#% )ons$(er#t$ons STUDY GUIDE RT 244 (Notes from Bushongs text) pg 4 pg ! 4 .L.R. principle: :aintain radiation exposures .s Low .s Reasonably .chievable. =6R#&s #n( /regn#n,& Radiobiology of /regnancy: T$me (epen(en,e 2first ' wee<s are safest6 4 (ose (epen(en,e 2'%% Rad dose will certainly cause radiation effects6. 3he /regnant Radiographer: DL F ! m5v9H months. 5hould wear ' film badges, one at collar, one at waist. /regnancy in Diagnostic Radiology 0etal Dose by Exam: .n ./ L-5pine exam of the mother gives the highest fetal dose. Des$gn$ng for R#($#t$on /rote,t$on Des$gn of =6r#& 3pp#r#tus Re>uirements of the )ontrol /anel: :ust show two things. *6 Display conditions of exposure. '6 /ositively indicate when x-rays are being produced. R#($#t$on /rote,t$on Des$gns .or =6r#& E>u$pment 5ource-to-;mage Distance ;ndicator: . tape measure. :ust be accurate to within '" of 5;D. )ollimation: Light localiIed, variable aperture. :ust be within '" of 5;D. *6 Light LocaliIer: Light bulb. '6 Gariable .perture )ollimation: )an be adDusted by the 3echnologist. 16 ?-ray field9 light field agreement. :ust be within '" of the 5;D. /ositive =eam Limitation 2/=L6: .utomatic )ollimators. :ust be accurate to within '" of the 5;D. =eam .lignment Device 2cross-hair target6: Line up the cross-hair target for proper tube9film alignment. 0iltration: '.!mm .luminum at (% <Gp. Des$gn of /rote,t$4e B#rr$ers 3ypes of Radiation: /r$m#r& R#($#t$on* 3he useful beam. *6 :ost of the radiation comes from primary beam. '6 :ost dangerous. 16 #ardest to shield against. /r$m#r& B#rr$ers* .ny wall to which the useful beam can be directed. Se,on(#r& R#($#t$on* ' types *6 5catter Radiation: )omes from the patient. '6 Lea<age Radiation )omes from the tube. Se,on(#r& B#rr$ers* 3he control booth barrier is a secondary barrier. Do not have to contain lead. R#($#t$on Dete,t$on #n( +e#surement STUDY GUIDE RT 244 (Notes from Bushongs text) pg : pg ! : T&pes of Dos$meters* *6 0ilm =adges: Csed most often. #ave a limited range. +ot reusable. '6 3hermoluminescent Dosimeter 23LD6: #ave a wide range. .re reusable. R#($#t$on /rote,t$on /ro,e(ures Est$m#t$on of /#t$ent Dose 5<in Dose: Easiest to measure using 3LD@s. 8onadal Dose: ;mportant because of suspected genetic response. GSD- 8enetically 5ignificant Dose. =one :arrow Dose: ;mportant because bone marrow is the target organ believed responsible for leu<emia. Re(u,t$on of -,,up#t$on#% Exposure* Do not aim the tube toward the control booth barrier. /ersonne% +on$tor$ng* Re>uired when you will receive more than *9,th the DL. 0ilm =adges: )heap, easy to use, easy to process, accurate and have been used for decades. 3LD: +ewer, can be worn for up to 1 months. /oc<et ;oniIation )hamber: :ust be charged daily before use. /#t$ent "o%($ng* Radiology personnel should never be used to hold patients. Cse family or friends of patient. Re(u,t$on of Unne,ess#r& /#t$ent Dose Cnnecessary Examinations: 3he technologist has no control over this. Repeat Examinations: 3he J * reason for high patient dose. Due to patient positioning over the photo-cells. Radiographic 3echni>ue: Cse high <Gp techni>ue to reduce patient dose. 3he ;mage Receptor: Cse the fastest film9screen combination to reduce patient dose. /atient /ositioning: =e sure the useful beam does not intercept the gonads if patient is seated for extremity films. 5pecific .rea 5hielding: 3he lens of the eye, breasts and gonads are fre>uently shielded from the primary beam. .rom N)R/ Report No? @ 1$m$t#t$on of Exposure to Ion$'$ng R#($#t$on Issue(* Summ#r& of Re,ommen(#t$ons .. -,,up#t$on#% exposures *. Effective dose limits a6 3nnu#% :< mS4;&r (: Rem;&r) b6 )umu%#t$4e < mS4 x 3ge ( Rem x 3ge) '. E>uivalent dose annual limits for tissues and organs a6 Lens of eye *!% m5v 2*! Rem6 b6 5<in, hands and feet !%% m5v 2!% Rem6 STUDY GUIDE RT 244 (Notes from Bushongs text) pg @ pg ! @ =. 8uidance for emergency occupational exposure 2not listed6 ). /ublic exposures 2annual6 are *9*%th the occupational exposures. *. Effective dose limit, continuous or fre>uent exposure * m5v 2%.* Rem6 '. Effective dose limit, infre>uent exposure ! m5v 2.! Rem6 1. E>uivalent dose limits for tissues and organs a6 Lens of eye *! m5v 2*.! Rem6 b6 5<in, hands and feet !% m5v 2! Rem6 ,. Remedial action for natural sources: a6 Effective dose 2excluding radon6 K! m5v b6 Exposure to radon decay products K( x *%-1 Lh m-1 D. Education and training exposures 2annual6 *. Effective dose limit *m5v 2%.* Rem6 '. E>uivalent dose limit for tissues and organs a6 Lens of eye *! m5v 2*.! Rem6 b6 5<in, hands and feet !% m5v 2! Rem6 E. Embryo-fetus exposures 2monthly6 *. E>uivalent dose limit %.! m5v 2.%! Rem6 0. +egligible individual dose 2annual6 %.%* m5v 2.%%* Rem6