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2 February 1997
Postoperative
FOCAL POINT
Management of the
★Careful attention to postoperative
management techniques in dogs
Canine Spinal Surgery
that have undergone spinal
surgery will improve surgical
success rates and client
Patient—Part I
satisfaction.
TABLE I
Drugs Used for Postoperative Pain Relief in Canine Spinal Surgery Patients
Dosage Duration
Drug (mg/kg) (hr) Side Effects
Opioids
Morphine 0.25–1.25 IM, SQ 3–5 Emesis; respiratory depression; increased
intracranial pressure
tion of cyclooxygenase, and thereby blocking the pro- The upper motor neuron bladder results from spinal
duction of prostaglandins during the inflammatory cord lesions between the pons and the lumbar spinal
process. NSAIDs have less sedative effect and a longer cord segment 7. Reflex micturition can occur, but vol-
duration of action than opioids. Although not as effec- untary control of urination is lost. Overflow inconti-
tive as opioids for the acute phase of postoperative nence without any attempt to urinate may be present
pain, NSAIDs can be administered 72 hours after in the early stages after surgery.22,24 Usually, urethral
surgery if pain persists. Because all NSAIDs can pro- sphincter tone is exaggerated, and the bladder may be
duce gastric irritation, caution must be exercised with extremely difficult to express.21,24 Several days to weeks
their use in patients that have undergone spinal surgery may pass before the sacral reflex is restored.22 When the
and that have previously received corticosteroids.8,10,14 upper motor neuron bladder persists for a prolonged
A new NSAID, carprofen, which is a weak inhibitor period, the animal urinates without awareness, and a
of cyclooxygenase, has been recently shown to have large residual volume of urine is usually retained after
equal or better analgesic effects than meperidine or pa- voiding.21–24
paveretum (a morphine-based opioid).19,20 Whether
carprofen is associated with gastrointestinal side effects Manual Bladder Expression and Catheterization
is unknown. 19,20 Additional studies are necessary to The primary goal of bladder management immedi-
evaluate its efficacy after spinal surgery. ately after surgery is to maintain normal or reduced
bladder volume and to prevent bladder overdisten-
Adequacy of Analgesia tion.24 Because the abdominal muscles are often tense
A recent retrospective study showed that dogs and after surgery, the bladder may be difficult to palpate.
cats may not be receiving adequate analgesia postopera- Ultrasonography can help determine the extent of blad-
tively; therefore, it is important for veterinarians to an- der distention. Alternatively, the patient can be cathe-
ticipate the likelihood of postsurgical pain and to ad- terized to measure urine volume.
minister appropriate analgesic therapy. 11 Animals Manual expression and intermittent or indwelling
should not be expected to tolerate pain any greater than catheterization can be used to help dogs void urine.
humans would voluntarily tolerate.11 Careful patient Our preference is for manual expression, except in dogs
monitoring and a sound knowledge of the pharmacolo- with excessive urethral tone or when nursing care is fa-
gy of analgesics are necessary to ensure that pain does cilitated by catheterization. Most dogs with lower mo-
not occur during the postoperative period. tor neuron bladders and some with upper motor neu-
ron bladders respond to manual expression. In smaller
BLADDER MANAGEMENT dogs, the caudal abdomen is gently squeezed with the
Bladder management is the most important and thumb and fingers of one hand while supporting the
most challenging issue faced after spinal surgery. Failure dog with the other hand.25 In larger dogs, both hands
to maintain adequate voiding of urine can lead to such are required to express the bladder. The pressure ap-
potentially severe problems as cystitis, bladder atony, plied should be firm enough to create a steady stream
pyelonephritis, and iatrogenic bladder rupture. The of urine.21 Initially, this procedure should be repeated
neurogenic bladder dysfunction that is generally seen in every 4 to 6 hours. This interval can be adjusted later,
patients with spinal cord disease is described on the ba- depending on the amount of bladder distention and
sis of location of the lesions (termed lower motor neuron the volume of urine voided (Figure 2).
bladder and upper motor neuron bladder). Catheterization of the bladder may be necessary in
The lower motor neuron bladder occurs with spinal dogs with neurogenic bladder dysfunction, particularly
cord lesions at the level of the sacral cord, cauda those with hypertonic urethral sphincters. Strict atten-
equina, pelvic nerve, and pudendal nerve. Such lesions tion to aseptic technique (e.g., using sterile catheters
abolish both the voluntary and reflex phases of normal and gloves) helps reduce the incidence of nosocomial
micturition. Consequently, contraction of the detrusor infections caused by bladder catheterization.26 The vul-
muscle is eliminated, and urethral sphincter muscle va or prepuce should be surgically prepared, and a ster-
tone is lost.21–24 The bladder retains urine, and overflow ile lubricant should be applied to the tip of the cathe-
incontinence results. Manual bladder expression is gen- ter.
erally straightforward, but voiding occurs only as long Catheters are made of a variety of materials, includ-
as external pressure is applied.23 In rare instances, inner- ing plastic, rubber, metal, glass, and nylon.26 Some dogs
vation to the internal sphincter via the hypogastric may have an inflammatory reaction to a particular type
nerve can remain intact, resulting in a bladder that is of catheter, but such responses seem to vary among
difficult to express.22,24 dogs and catheters. 27 A red rubber feeding tube or
TABLE II
Drugs Used for Pharmacologic Management of Neurogenic Bladder Dysfunction
Drug Dosage Clinical Effects Side Effects
Phenoxybenzamine 5–15 mg SID, PO α-Adrenergic; reduces hypertonicity Hypotension, tachycardia
of internal urethral sphincter
Dantrolene 1–5 mg/kg BID, PO Direct skeletal muscle relaxant Weakness, hepatotoxicity
BID = twice daily, PO = orally, SID = once daily, TID = three times daily.
reduced by using the α-adrenergic blocking agent phe- muscle atrophy and fibrosis may be prevented.36,37
noxybenzamine. Response to treatment depends on the A well-designed physical therapy program can de-
type of lesion. An assessment of effectiveness may re- crease the duration of hospitalization and help to im-
quire several days. Treatment should be discontinued prove patient attitude and mental status.37 Initiation of
after 1 to 2 weeks if no clinical response is seen.22–24,33 physical therapy depends on the location and severity
Detrusor contractility may be enhanced with the of the lesion; the surgical technique performed; and the
cholinergic drug bethanechol. The extent of detrusor animal’s condition, attitude, and demeanor.
atony determines the clinical response to this drug. If
no response is seen after 1 week of treatment, therapy Cold Therapy
should be considered to be ineffective. In addition, Cold therapy using the conduction of cold with cold
bethanechol has a weak nicotinic effect on the bladder packs, cold water, or ice may be indicated in the first
neck, which can increase urethral outflow resistance. 12 to 48 hours after surgery. Local hypothermia de-
For this reason, bethanechol may be used most effec- creases nerve conduction velocity (creating mild analge-
tively in combination with phenoxybenzamine. sia), causes vasoconstriction (reducing edema), and re-
Bethanechol should not be used if urethral obstruction laxes skeletal muscles.36–39
is suspected.22–24,33 Cold packs should be placed over a sterile, water-
The tone of the external urethral sphincter, which impermeable dressing and should be kept in place for 5
consists of skeletal muscle, may be reduced by using di- to 10 minutes, two to four times daily. Treatments
azepam.22–24,33 Less frequently used drugs for bladder should never exceed 30 minutes because extended cold
management include dantrolene, phenylpropanola- therapy sessions may lead to vasodilatation and subse-
mine, and propantheline.22–24,33 quent edema formation.36
Commercially produced cold packs that are available
PHYSICAL THERAPY for human physical therapy can be adapted for use in
After spinal surgery, patients are often recumbent and dogs. A simple ice pack can be constructed by filling a
confined to their cages. Physical therapy plays a key plastic bag with ice, wrapping the bag in a towel, and
role in hastening successful recovery. Physical therapy placing the bag on the wound.36–39
can improve muscular strength and speed the healing of
inflamed and injured tissues while helping to maintain Heat Therapy
the normal range of motion in joints.34–36 In addition, Heat therapy is indicated from 48 to 72 hours after
and preemptive use of analgesic agents to manage pain dogs and cats in a veterinary teaching hospital: 258 Cases
results in less patient apprehension and distress when (1983–1989). JAVMA 202(9):1485-1994, 1993.
12. Bednarski RM: Anesthesia and pain control. Vet Clin North
the important phases of bladder management and
Am Small Anim Pract 19(6):1223–1238, 1989.
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nose and treat urinary tract infections. Contin Educ Pract Vet 13(2):181–191, 1991.
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apy, heat therapy, massage, and passive and active exer- 16. Plumb DC: Veterinary Drug Handbook. Ames, IA, Iowa
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Drs. Jerram and Hart are affiliated with the Department of and sedative effects of carprofen and papaveretum in the
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The Compendium February 1997 Small Animal
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